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All Journal Jurnal Biologi Tropis JIMKI : Jurnal Ilmiah Mahasiswa Kedokteran Indonesia
Nur Feby Febiana Agistany
Universitas Mataram
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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HIPERTENSI, DIABETES MELLITUS, DAN OBESITAS SEBAGAI FAKTOR KOMORBIDITAS UTAMA TERHADAP MORTALITAS PASIEN COVID-19: SEBUAH STUDI LITERATUR Luh Ade Dita Rahayu; Jannatul Cahya Admiyanti; Yumna Iftinan Khalda; Fatikha Rudia Ahda; Nur Feby Febiana Agistany; Sastraningsih Setiawati; Nabila Indah Shofiyanti; Cut Warnaini
JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia Vol 9 No 1 (2021): JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia Volume 9.1 Edisi Maret - Juli
Publisher : BAPIN-ISMKI (Badan Analisis Pengembangan Ilmiah Nasional - Ikatan Senat Mahasiswa Kedokteran Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53366/jimki.v9i1.342

Abstract

Background: COVID-19 patients with comorbid diseases have a higher mortality rate than patients without congenital diseases. The most common comorbids found in COVID-19 patients are diabetes mellitus, hypertension, and obesity. The prevalence of COVID-19 patients with diabetes mellitus reached 41.7%, hypertension reached 56.6%, and obesity reached 41.7%. Methods: The method used in this paper is literature review from various references and focused on the correlation of comorbid with the risk of death in COVID-19 patients. The references are being retrieved from NCBI and Google Scholar. Overall, 21 sources were used which were obtained from various data bases including PubMed, ScienceDirect, Researchgate, and WHO. Discussion: There is an increase in ACE-2 expression which causes a high susceptibility to SARS-CoV-2 infection on COVID-19 patient with hypertension. Impaired T-cell function and increased levels of interleukin-6 (IL-6) also play an important role in increasing the severity on COVID-19 patient with diabetes. Obesity can cause abnormalities in the secretion of cytokines, adipokines, and inferferon which will disrupt the immune system in the human body. Conclusion: The complex pathophysiological mechanisms of hypertension, diabetes mellitus, and obesity as comorbid in COVID-19 patients increase the severity and mortality risk.
Inguinal Hernia: Diagnosis and Management Nabila Aisyah Putri; Nur Feby Febiana Agistany; Raditya Bayu Farizil Akhyar; Salsabila Chauna; Wardha Novia Annisa; Zikrul Haikal
Jurnal Biologi Tropis Vol. 23 No. 1 (2023): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v23i4b.5721

Abstract

The inguinal hernia is the subcutaneous part of the peritoneum containing the abdominal viscera that exits through the inguinal canal or directly through the abdominal wall. Most patients do not realize they have an inguinal hernia until swelling arises in the thigh fold area or pain in the groin area. The purpose of this literature review is to provide an update regarding the diagnosis and management of inguinal hernias. The diagnosis of an inguinal hernia is largely based on the history and physical examination, whereas imaging is rarely performed unless there is a certain suspicion. Surgical management can be performed on patients with symptoms, while asymptomatic patients can be subjected to conservative therapy.
Co-Authors Cut Warnaini Fatikha Rudia Ahda Jannatul Cahya Admiyanti Luh Ade Dita Rahayu Nabila Aisyah Putri Nabila Indah Shofiyanti Raditya Bayu Farizil Akhyar Salsabila Chauna Sastraningsih Setiawati Wardha Novia Annisa Yumna Iftinan Khalda Zikrul Haikal