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Formulasi Dan Evaluasi Sediaan Face Mist Spray Minyak Atsiri Serai Dapur (Cymbopogon citratus) Sebagai Pelembab Yeni Maria; Titi Agni Hutahaen; Abdul Basith
Indonesian Journal of Health Science Vol 3 No 2a (2023): Terus Melaju Untuk Indonesia Maju
Publisher : PT WIM Solusi Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54957/ijhs.v3i2a.515

Abstract

Serai dapur (Cymbopogon citratus) adalah tanaman yang mengandung minyak atsiri dengan komposisi senyawa antioksidan yang berpotensi sebagai zat aktif dalam sediaan face mist spray sebagai pelembab alami wajah yang digunakan untuk memperlambat penuaan dini yang disebabkan oleh radikal bebas. Penelitian ini bertujuan untuk menentukan minyak atsiri sereh dapur (Cymbopogon citratus) dapat diformulasikan menjadi bentuk sediaan face mist spray. Penelitian ini merupakan penelitian true experimental laboratory menggunakan jenis penelitian kuantitatif dengan desain penelitian yang digunakan adalah Completely Randomized Design atau Rancangan Acak Lengkap (RAL). Evaluasi pada sediaan yaitu dilakukan uji organoleptis, uji pH dan uji kelembaban wajah. Berdasarkan hasil penelitian, menunjukkan bahwa minyak atsiri serai dapur (Cymbopogon citratus) dapat digunakan sebagai zat aktif dalam pembuatan sediaan face mist spray. Dan formulasi yang sediaan face mist spray yang terbaik diperoleh pada F2 yaitu dengan konsentrasi minyak astiri serai dapur (Cymbopogon citratus) sebanyak 3gr
FORMULASI DAN UJI EVALUASI SEDIAAN STICK BALSEM DARI MINYAK ATSIRI SERAI DAPUR (Cymbopogon citratus) SEBAGAI ANALGESIK DAN AROMATERAPI RELAKSAN Ellyza Audhina Rachman; Titi Agni Hutahaen; Ainu Zuhriyah
Jurnal Farmasi Medica/Pharmacy Medical Journal (PMJ) Vol. 6 No. 2 (2023): Vol. 6, No.2, 2023
Publisher : Sam Ratulangi University

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Lemongrass essential oil (Cymbopogon citratus) has potential as a medicine because it contains chemical compounds citronellal, citronellol, geraniol which work as analgesics and aromatherapy. One of the pharmaceutical preparations that can be used for analgesic and aromatherapy is a stick balm preparation because it can treat mild scale pain and stress. The aim of this study was to analyze the chemical compounds in citronella essential oil using the GCMS tool, to formulate it as a stick balm which has a function as an analgesic and aromatherapy as well as to evaluate the preparation. The method in this study is true experimental laboratory. Lemongrass essential oil is formulated into 4 different preparations. The results of testing citronella essential oil using GCMS did not meet the expectations of the researchers because the results did not read the compound being sought. The results of the data read the chemical compound groups that are thought to have the same function as citronellal, citronellol, geraniol. Aldehydes and alcohols. Lemongrass essential oil can be formulated into 4 balm sticks with different concentrations. Evaluation test of stick balm organoleptic test, homogeneity test, pH test, adhesion test, spreadability test, analgesic test, aromatherapy test and irritation test. The results of all preparation evaluation tests have met Indonesian national standards.  
The Effect of taro tuber (colocasia esculenta L) infusion formulation on reducing cholesterol levels in female mice (mus musculus): Effect of taro tuber (colocasia esculenta L) infusion formulation on reducing cholesterol levels in female mice (mus musculus) intan khoiriyah; titi agni hutahaen; ainu zuhriyah
Jurnal Farmasi Medica/Pharmacy Medical Journal (PMJ) Vol. 6 No. 2 (2023): Vol. 6, No.2, 2023
Publisher : Sam Ratulangi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/pmj.v6i2.50557

Abstract

Cholesterol is an essential building material for the body for the synthesis of important substances such as cell membranes and insulating materials around nerve fibers, as well as sex hormones, and kidney children, vitamin D, and bile acids. This study aims to determine which group of phytochemical compounds contained in liquid extract of taro tuber (Colocasia esculenta L.) has activity as a lowering of cholesterol levels and to determine whether taro tuber infusion (Colocasia esculenta L.) can reduce cholesterol levels in female mice. The dose used was the F1 dose of 0.3 ml/30 gram BW/day, the F2 dose was 0.6 ml/30 gram BW/day and the F3 dose was 0.9 ml/30 gram BW/day, in the K+ group using simvastatin 10 mg and K- using aqua injection. The results showed that at a dose of 0.3 ml/30 grams BW/day there was a relatively high reduction in cholesterol levels, namely 61 mg/dL, at a dose of 0.6 ml/30 grams BW/day it decreased by 48.8 mg/dL and at a dose of 0.9 ml /30 gram BW/day decreased with a low average of 19.4 mg/dL. However, a dose of 0.9 ml/30 gram BW/day is the best dose because it can reduce cholesterol levels quickly