Garuda - Garba Rujukan Digital

p-Index From 2019 - 2024

1.931

P-Index

This Author published in this journals

All Journal Biosfer: Jurnal Tadris Biologi KOVALEN: Jurnal Riset Kimia Jurnal Kimia Mulawarman Journal of Islamic Pharmacy Jurnal Farmasi Sains dan Komunitas (JFSK) Jurnal Kreativitas PKM BERNAS: Jurnal Pengabdian Kepada Masyarakat Bakti Cendana: Jurnal Pengabdian Masyarakat Jurnal Sains dan Edukasi Sains Jurnal Biosense Aptekmas : Jurnal Pengabdian Kepada Masyarakat Journal of The Indonesian Society of Integrated Chemistry

Maximus M Taek

Universitas Katolik Widya Mandira

Author-ID : 5569670

Religion Aerospace Engineering Agriculture, Biological Sciences & Forestry Arts Humanities Astronomy Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Mathematics Mechanical Engineering Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Transportation Veterinary Other

Published : 13 Documents Claim Missing Document

Claim Missing Document

Articles

1 2

KAJIAN SENYAWA HEXOSE DAN MALIC ACID SEBAGAI INHIBITOR PAPAIN LIKE PROTEASE (PLPro) CORONA VIRUS Yohanes Bare; Frederiksen Novenrius Sini Timba; Sukarman Hadi Jaya Putra; M A Yohanita Nirmalasari; Dewi Ratih Tirto Sari; Maximus M Taek
JURNAL BIOSENSE Vol 5 No 01 (2022): Edisi Juni 2022
Publisher : Program Studi Biologi, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas PGRI Banyuwangi, Jalan Ikan Tongkol No 01, Telp (0333) 421593, 428592 Banyuwangi 68416

Papain-like protease is a SARSCOV-2 protease that functions for ubiquitination in host cells. Caffeine compounds have been widely reported to have antioxidant, anti-inflammatory, antidiabetic, and antiobesity activities. However, hexose and malic acid compounds in coffee rind as potential inhibitors of the papain-like protease SARSCOV2 have not been reported. This study investigated the potential of malic acid and hexose compounds as PLPro inhibitor agents in inhibiting SARSCOV2 ubiquitination. In silico studies were used to identify the potential of the two compounds by interacting hexose and malic acid compounds with papain-like protease (PLPro) proteins with the Molegro virtual Docker 5 program. Next, the ligand-protein complex visualization was done with discovery studio version 5.0. hexose and malic acid compounds showed interactions with papain-like protease proteins on several active site residues. The interactions showed inhibition of ubiquitination and stimulation of interferon in host cells. The two compound complexes – PLPro protein showed hydrophobic interactions, hydrogen bonds, and van der Waals forces, which contributed to the formation of bond energy and strong bonds between compounds and proteins. In this study, it was concluded that hexose and malic acid compounds have the potential to act as inhibitors of papain-like protease (PLPro) protein.

Berberine: A Potential Inhibitor of Dihydrofolate Reductase- Thymidylate Synthase (DHFR-TS) for Malaria Yohanes Bare; Dewi Ratih Tirto Sari; Angeliana Desimaris Nita; Maximus M Taek
Biosfer: Jurnal Tadris Biologi Vol 13, No 1 (2022): Biosfer: Jurnal Tadris Biologi
Publisher : UNIVERSITAS ISLAM NEGERI RADEN INTAN LAMPUNG

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24042/biosfer.v13i1.11145

The goal of this study was to genetically link natural materials derived from Tinospora crispa L with Berberine to dihydrofolate reductase-thymidylate synthase (DHFR-TS). Method: The ligand berberine (CID: 2353) was obtained from Pubchem, while the protein DHFR-TS (PDB ID 2bl9) was obtained from Protein Data Bank. The ligands and proteins interacted with HEX 8.0.0.0 and were visualized with Discovery Studio. The researchers discovered a positive interaction between berberine and DHFR-TS, observed at four amino acid residues that bind to the protein TYR125, ILE121, LEU45, and MET54. Van der Waals interactions, hydrogen bonds, Pi-Sulfur, Pi-Alkyl, and Pi-Stalked interactions all contribute to strength and stability. In conclusion, berberine has the potential to act as a DHFR-TS inhibitor and thus prevent malaria.ABSTRAK: Tujuan penelitian ini adalah memanfaatkan bahan alam yang berasal dari Tinospora crispa L dengan kandungan utama Berberin dengan dihydrofolate reductase-thymidylate synthase (DHFR-TS) secara genetik. Metode, Ligan berberin (CID: 2353 ) diperoleh dari Pubchem sedangkan protein DHFR-TS (PDB ID 2bl9) diperoleh dari Protein Data Bank, ligan dan protein diinteraksikan menggunakan HEX 8.0.0.0 dan divisualisasikan menggunakan discovery studio. Ditemukan interaksi positif antara berberin dan DHFR-TS yang menunjukkan interaksi pada empat residu asam amino yang berikatan dengan protein. Mereka adalah TYR125, ILE121, LEU45 dan MET54. Beberapa interaksi yang dilakukan Van der Waals, ikatan hidrogen, Pi-Sulfur, Pi-Alkyl dan Pi-Stalked juga memberikan dukungan dalam rangka meningkatkan kekuatan dan stabilisasi. Kesimpulannya, berberin memiliki potensi fungsi sebagai penghambat DHFR-TS dan mengarah pada malaria.

The Effect of Ethanol Extract of Marsilea crenata Presley Leaves on Rotenone-Induced Zebrafish Locomotor Activity Burhan Ma'arif; Faisal Akhmal Muslikh; Destiya Argo Pamuji Fihuda; Husnul Khotimah; Maximus M. Taek; Mangestuti Agil
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 19, No 2 (2022)
Publisher : Sanata Dharma University

Neurodegenerative diseases are mostly experienced by postmenopausal women and are often caused by estrogen deficiency, so it is necessary to replace the hormone estrogen in the form of phytoestrogens. One of the plants that contain phytoestrogens is Marsilea crenata. The objective of this study is to see if giving rotenone-induced zebrafish a 96% ethanol extract of M. crenata leaves increases locomotor activity. This research was conducted by inducing 5 µg/L rotenone as a compound that will interfere with the locomotor activity of zebrafish. Next, treatment was given with 96% ethanol extract of clover in each group with a dose of 2.5; 5; 10; and 20 mg/mL to determine the effect of the extract on increasing locomotor activity of rotenone-induced zebrafish. Observations were made by looking at the quantity of zebrafish swimming every five minutes until day 28. The treatment of 96% ethanol extract of M. crenata leaves could significantly increase zebrafish motility at the optimum dose of 2.5 mg/mL, because every week the zebrafish locomotor activity increased compared to the negative control. M. crenata leaves extract is proven to prevent neurodegenerative diseases. However, further research needs to be done on the degenerative effects of rotenone every week.

Profil Senyawa Metabolit Sekunder dalam Minyak Atsiri Tumbuhan Legundi (Vitex trifolia Linn) yang Tumbuh di Pulau Timor Christiani Dewi Q. M. Bulin; Gerardus D. Tukan; Angela Nona; Maximus Markus Taek
Journal of Islamic Pharmacy Vol 7, No 2 (2022): J. Islamic. Pharm.
Publisher : Universitas Islam Negeri Maulana Malik Ibrahim Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jip.v7i2.17698

Penelitian ini dilakukan dengan tujuan untuk mengetahui profil senyawa-senyawa metabolit sekunder dalam minyak atsiri daun tumbuhan legundi (Vitex trifolia Linn) yang tumbuh di Pulau Timor. Minyak atsiri dari sampel daun tumbuhan legundi diekstraksi menggunakan distilasi uap air dengan menggunakan sampel yang masih segar sedangkan analisis senyawa metabolit sekunder dalam minyak atsiri dilakukan dengan GC-MS. Hasil penelitian yang terdapat dalam sampel minyak atsiri daun legundi asal Pantai Paradiso, Kelurahan Oesapa Barat, Kota Kupang sebanyak 49 senyawa. Senyawa-senyawa yang dominan ada 12 yakni trans- Kariopillen 25,43%, 1,2-asam Benzendikarbosilik 14,16%, Sabinen 7,57%, 1,8-Sineol 4,17%, Kariopillen oksida 3,71%, Skareol 3,21%, α-Humulen 3,07%, α-Terpinenil asetat 2,36%, Sitronella 2,30%, 3-Sikloheksanol 1,76%, α-Pinen 1,76%, β-Pinen 1,68%.

Profil Senyawa Metabolit Sekunder Dalam Minyak Obat Ramuan Tradisional Masyarakat Sandosi Adonara Dan Masyarakat Lamatuka Lembata Maria Vitriani Barek Sabon; Gerardus Diri Tukan; Christiani Dewi Q. M. Bulin; Maximus Taek
JURNAL KIMIA MULAWARMAN Vol 20 No 1 (2022)
Publisher : Jurusan Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Mulawarman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30872/jkm.v20i1.1134

Penelitian ini dilakukan dengan tujuan untuk mengetahui tumbuh-tumbuhan yang digunakan dalam pembuatan minyak obat tradisional masyarakat Sandosi di pulau Adonara dan masyarakat Lamatuka di pulau Lembata serta kandungan senyawa dalam minyak obat tradisional yang digunakan dan manfaat senyawa-senyawa yang terkandung. Metode penelitian yaitu wawancara untuk mengetahui jenis-jenis tumbuhan yang digunakan dalam pembuatan ramuan minyak obat, serta analisis senyawa dalam sampel ramuan minyak obat tradisional menggunakan GC-MS. Hasil penelitian yang diperoleh bahwa tumbuhan yang digunakan dalam pembuatan ramuan minyak obat tradisional masyarakat Sandosi yakni 3 jenis tumbuhan dan masyarakat Lamatuka 45 jenis tumbuhan. Senyawa dominan dari hasil analisis GC-MS ramuan minyak obat tradisional masyarakat Lamatuka antara lain: senyawa asam laurat, asam miristat, Dilauri, Tridecanal, asam oleat, oleamide, 1,3-dipalmitin, trilaurin, trioctanoin dan corwin. Sedangkan senyawa dominan pada ramuan minyak obat tradisional masyarakat Sandosi Adonara antara lain: senyawa asam laurat, asam palmitat, asam oleat, delta decalactone, oxacyclododecan-2-one, 10-undecenyl chloride, 9-octadecenal, asam tridekanoat, ethyl trans-3-(2-oxo-5-methylcyclohexyl) propionate, delta dodecalactone, trioctanoin, 10-Undecenoic acid, methyl ester dan oleamide

Penguatan Kapasitas Pengelolaan BUMDes Di Desa Pariti, Kecamatan Sulamu Kabupaten Kupang-NTT Anselmus Boy Baunsele; Erly G. Boelan; Gerardus Diri Tukan; Maximus M. Taek; Maria Agustin Lopes Amaral; Hildegardis Missa; Adri Gabriel Sooai; Alfry A. J. Sinlae; Paulus A. K. L. Ratumakin; Adrianus Ketmoen
Bakti Cendana Vol 6 No 1 (2023): Bakti Cendana: Jurnal Pengabdian Masyarakat
Publisher : LPPM Universitas Timor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32938/bc.6.1.2023.37-48

Badan Usaha Milik Desa (BUMDes) merupakan suatu badan usaha berbadan hukum, yang bertujuan untuk dapat meningkatkan perekonomian desa khususnya untuk peningkatan kesejahteraan masyarakat. Kegiatan penguatan kapasitas pengelolaan BUMDes dan sharing pengalaman pengelolaannya dalam kegiatan pengabdian pada masyarakat ini, bertujuan untuk dapat memberikan pengetahuan dan pengalaman baru bagi masyarakat. Kegiatan ini dilaksanakan di Desa Pariti, Kecamatan Sulamu, Kabupaten Kupang. Kegiatan ini diikuti oleh 20 oang peserta diantaranya Pemerintah Desa, pengurus BUMDes Gempar dan tokoh masyarakat. Metode pelaksanaan berupa sosialisasi melalui ceramah dan diskusi, sharing pengalaman dengan Kepala Desa Hadakewa serta hasil tes kemampuan (pre test dan post test). Kesimpulan dari hasil kegiatan ini yaitu terdapat peningkatan kemampuan terhadap substansi dan sistem tata kelola BUMDes. Kedepannya kegiatan ini dapat dilanjutkan dengan menghadirkan narasumber-narasumber yang telah sukses mengelola BUMDes

SOSIALISASI POLA HIDUP BERSIH DAN SEHAT DALAM UPAYA PENCEGAHAN STUNTING DI DESA MANLETEN KABUPATEN BELU Anselmus Boy Baunsele; Ambrosius Faofeto; Hildegardis Missa; Aloysius Djalo; Sardina Ndukang; Anggelinus Nadut; Gerardus D. Tukan; Maximus M. Taek; Adri Gabriel Sooai
Aptekmas Jurnal Pengabdian pada Masyarakat Vol 6 No 1 (2023): APTEKMAS Volume 6 Nomor 1 2023
Publisher : Politeknik Negeri Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36257/apts.v6i1.4839

The healty lifestyle is a habits that needs to be used as a principle of life by every people to improving the life quality especially for the health sector. The good comprehension of health can help every people for stunting prevention. Stunting is a kind of disease that caused by the poor nutrition of meals for the children for their growing period. By the community service program of public education of high nutrition food for the parents to increase the nutrition grade for these children is expected to prevent the potential for stunting in these children. In addition, this community service program give the new experience for the community to utilize the ingridients food to create the high nutrition food with low price and can produce in every household. Babanas and corn are abundantly available in Manleten Village and always consumed by the conventional processing can be produced to be a new variant of food that can be a new food reference

Pelatihan Penyusunan Administrasi dan Laporan Keuangan BUMDES Nekbaun Desa Baumata Timur Viany Cecilia Pah; Adrianus Ketmoen; Maria Augustin Lopes Amaral; Alfry Aristo J. Sinlae; Paskalis A. Nani; Paulus A. K. L. Ratumakin; Maximus M. Taek; Gerardus D Tukan; Anselmus Boy Baunsele; Erly Grizca Boelan
BERNAS: Jurnal Pengabdian Kepada Masyarakat Vol. 4 No. 2 (2023)
Publisher : Universitas Majalengka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31949/jb.v4i2.4932

Sebagai suatu badan usaha yang ada di desa, BUMDes wajib dikelola dengan baik dengan memperhatikan penataan administrasi dan laporan keuangan BUMDes. Oleh karena itu semua aktivitas usaha BUMDEs wajib dicatat dan dibukukan. Melihat pentingnya hal ini maka Tim Pengabdian Universitas Katolik Widya Mandira melaksanakan kegiatan penguatan kapasitas BUMDes berupa Pelatihan penyusunan administrasi dan laporan keuangan bagi BUMDes Nekbaun yang ada di Desa Baumata Timur. Tujuan dari kegiatan pelatihan ini adalah untuk menambah pengetahuan masyarakat khususnya pengelola BUMDes dalam penataan administarsi dan pengelolaan keuangan BUMDes. Kegiatan Pelatihan ini dilaksanakan dengan menggunakan metode ceramah dan diskusi kemudian dilanjutkan dengan latihan studi kasus. Hasil dari kegiatan pelatihan ini adalah peserta mendapat pengetahuan baru mengenai pencatatan administrasi dan laporan keuangan. Selain itu ditemukan adanya kelemahan pada Sumber Daya Manusia sehingga pencatatan terhadap aktivitas dan kondisi BUMDes tidak terekam dengan baik. Dengan adanya kegiatan pelatihan penyusunan administrasi dan laporan keuangan dapat menambah pengetahuan dan ketrampilan pengelola BUMDes dalam melaksanakan seluruh aktivitas BUMDes

Penggunaan Sabut Kelapa Teraktivasi NaOH sebagai Adsorben Metilen Biru: Utilization of Coconut Fiber NaOH-Activated as Blue Methylene Adsorbent Anselmus Boy Baunsele; Erly Grizca Boelan; Aloisius Masan Kopon; Maximus M. Taek; Gerardus D. Tukan; Hildegardis Missa
KOVALEN: Jurnal Riset Kimia Vol. 9 No. 1 (2023): April Edition
Publisher : Chemistry Department, Mathematics and Natural Science Faculty, Tadulako University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/kovalen.2023.v9.i1.16274

Methylene blue is a textile dye with carcinogenic and mutagenic properties which can cause various problems for the environment and organisms, therefore it is necessary to treat the waste. This study describes the adsorption of methylene blue using base-activated coconut coir. Coconut coir as waste was prepared into 80 mesh-sized powder and then activated using NaOH solution. The base-activated coconut fiber was then used for methylene blue adsorption under several optimization conditions such as pH, contact time, concentration, and adsorption isotherm. The determination of methylene blue was adsorbed by the adsorbent measured using UV-VIS. The pH and contact time results were 7 and 75 minutes, respectively, with the adsorption capacity (qe) of 1.98 mg g-1 and 99.91%. The isotherm adsorption of blue methylene followed the Langmuir isotherm model with the maximum adsorption capacity (Qmax) of 0.2 mg -1. The result showed that the coconut fiber base activated could be used as a dye adsorbent.

Penyesuaian Anggaran Dasar dan Anggaran Rumah Tangga Bumdes Ina Huk Berdasarkan Peraturan Pemerintah Nomor 11 Tahun 2021 dan Peraturan Menteri Desa Pembangunan Daerah Tertinggal dan Transmigrasi Nomor 3 Tahun 2021 Paulus Adrianus K. L. Ratumakin; Maria O. Krisdayanti; Adrianus Ketmoen; Anselmus Boy Baunsele; Erly G Boelan; Gerardus Diri Tukan; Maximus M Taek; Maria Augustin Lopes Amaral; Paskalis A Nani; Alfry Aristo Jansen Sinlae; Priscilla M. A Hornay
Jurnal Kreativitas Pengabdian Kepada Masyarakat (PKM) Vol 6, No 5 (2023): Volume 6 No 5 Mei 2023
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jkpm.v6i5.9253

ABSTRAK Badan Usaha Milik Desa (BUMDes) sebelumnya didefinisikan hanya sebagai badan usaha. Namun setelah Undang-Undang Cipta Kerja disahkan, BUMDes merupakan badan usaha yang berbadan hukum. Konsekuensinya ada beberapa perubahan regulasi dan kelengkapan dokumen yang dituntut untuk pengurusan badan hukum BUMDes. Salah satunya yakni penyesuaian Anggaran Dasar (AD)/ Anggaran Rumah Tangga (ART) BUMDes. AD/ART BUMDes merupakan rujukan peraturan dasar dan turunan dalam pengelolaan BUMDes. Tantangan dalam penyusunan AD/ART yakni tidak semua warga desa, bahkan Pemerintah Desa dan Pengurus BUMDes paham proses penyusunan, substansi AD/ART, serta struktur dalam AD/ART. Karena itu, pelatihan penyusunan AD/ART sesuai regulasi baru dibutuhkan untuk memperbaiki, sekaligus menyepakati poin substansial dalam isi AD/ART BUMDes. Kegiatan ini dilakukan di LPPM Universitas Katolik Widya Mandira yang melibatkan 15 orang peserta dari perwakilan pengurus BUMDes Ina Huk, pemerintah desa, BPD, pelaku usaha, tokoh masyarakat, perwakilan perempuan, kaum muda dan warga Desa Mata Air, Kecamatan Kupang Tengah, Kabupaten Kupang. Kata Kunci: BUMDes, Anggaran Dasar, Anggaran Rumah Tangga ABSTRACT Village-owned Enterprises (BUMDes) were previously only defined as business entities. However, after the Job Creation Law was passed, BUMDes is now a legal entity. Consequently, there have been several regulatory changes and the complete documents required for managing BUMDes legal entities. One of them is the adjustment of the BUMDes Statutes (AD)/Bylaws (ART). BUMDes AD/ART is a reference for primary and derivative regulations in BUMDes management. The challenge in preparing AD/ART is that not all villagers, even the Village Government and BUMDes management, understand the drafting process, the substance of AD/ART, and the structure of AD/ART. Therefore, training on drafting AD/ART following the new regulations is needed to improve and, at the same time, agree on essential points in the contents of BUMDes AD/ART. This activity was carried out by the LPPM of Widya Mandira Catholic University which involved 15 participants from BUMDes Ina Huk officials, village government representatives, BPD, business actors, community leaders, women's representatives, youth and residents of Mata Air Village, Kupang Tengah District, Kupang Regency. Keywords: Village-owned Enterprises, Statutes (AD), Bylaws (ART)

Co-Authors Adilson de Castro Ruas Adri Gabriel Sooai Adrianus Ketmoen Alfry Aristo Jansen Sinlae Aloisius Masan Kopon Aloysius Djalo Ambrosius Faofeto Angela Nona Angeliana Desimaris Nita Anggelinus Nadut Anselmus Boy Baunsele Bare, Yohanes Burhan Ma'arif Christiani Dewi Q. M. Bulin Destiya Argo Pamuji Fihuda Erly Grizca Boelan Faisal Akhmal Muslikh Gerardus Diri Tukan Hildegardis Missa Husnul Khotimah Juvencio de Castro Ruas Lodowik Landi Pote Lusia Ina Dai M A Yohanita Nirmalasari Mangestuti Agil Maria Aloisia Uron Leba Maria Augustin Lopes Amaral Maria O. Krisdayanti Maria Vitriani Barek Sabon Noemia A. Ruas Paskalis Andrianus Nani Paulus Adrianus K. L. Ratumakin Priscilla M. A Hornay Sardina Ndukang Sari, Dewi Ratih Tirto Sisilia Daeng Bakka Mau Timba, Frederiksen Novenrius Sini Viany Cecilia Pah Yustina Dwisofiani Lawung

Title

Found 13 Documents
Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title Search

Found 13 Documents Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title

Found 13 Documents
Search