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All Journal Biologi Edukasi : Jurnal Ilmiah Pendidikan Biologi Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Celebes Biodiversitas : Jurnal Sains dan Pendidikan Biologi Jurnal Profesi Medika: Jurnal Kedokteran dan Kesehatan AGROLOGIA : Jurnal Ilmu Budidaya Tanaman Biopendix: Jurnal Biologi, Pendidikan dan Terapan Molucca Medica Jurnal Karya Abdi Masyarakat PAMERI : Pattimura Medical Review Rumphius Pattimura Biological Journal
Nindatu, Maria
Jurusan Biologi Fakultas MIPA Universitas Pattimura Ambon
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Computer Science & IT Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Other

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Journal : Jurnal Profesi Medika: Jurnal Kedokteran dan Kesehatan

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Aplikasi Ekstrak Kulit Buah Naga Merah (Hylocereus polyrhizus) Pada Nata De Coco Dalam Menurunkan Kadar Kolesterol Total, LDL, Dan Meningkatkan HDL Pada Mencit (Mus musculus) Watuguly, Theopilus Wilhelmus; Uniarti, Anik; Nindatu, Maria
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 13, No 1 (2019): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (232.29 KB) | DOI: 10.33533/jpm.v13i1.691

Abstract

Hypercholesterolemic sufferers generally consume conventional drugs using hypolipidemic drugs to reduce cholesterol levels. But this type of drug also has side effects. In addition to consuming hypolipidemic drugs, increased cholesterol levels can be suppressed by regulating dietary patterns by controlling nutrient intake in a balanced manner as needed. Red dragon fruit skin extract (Hylocereus polyrhizus) applied to nata de coco is believed to reduce cholesterol levels because both contain fiber which can be used for dietary needs, and improve the digestive process. The purpose of this study was to determine the application and determine the dose of red dragon fruit skin extract (Hylocereus polyrhizus) in nata de coco in reducing total cholesterol, LDL and increasing HDL in mice (Mus musculus). The type of research used is experimental research using the Pre-Post Test Only Control Group Design research design that uses 18 mices with different doses of 1: 1 and 1: 2 doses. ANOVA statistical test on the results of the study showed that effective treatment in reducing total cholesterol, LDL, and increasing HDL was treated with extracts of red dragon fruit skin (Hylocereus polyrhizus) in a 1: 2 nata de coco. Thus it can be concluded that the higher the dosage given to mice tested it showed a significant reduction in cholesterol levels.
Co-Authors Abraham Simatupang Adriana Hiariej, Adriana Adrien Jems Akiles Unitly Alien Bastian Amos Killay Camelia Gracia Pattinasarany Deansatya Febrian Wambrauw Debby Sanders Eka Astuty Farah Noya Faustinus Sarbunan Gasperz, Westi C Gratia Mayaut Hosyiana Putri Matauseja Huningkor, Yusuf Hutagalung, Inggrid Kailola, Natalie Laura B. S. Huwae Leny Noya Marissa Matinahoru Martha Kaihena Moniharapon, Debby Nia D. Laratmase Nia Laratmase Noya, Farah Prichilia Daro Rahel Hendrijete de Kock Sanaky, Marliyati Siska Teurupun Stesiana Latuputty Sulfiana , Suyono Lateke Theopilus W Watuguly Titus Frendi Wedilena Uniarti, Anik Yandris Kapuate Yolanda, Denny Yuniasih MJ Taihuttu Yuniasih Taihuttu