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All Journal Biologi Edukasi : Jurnal Ilmiah Pendidikan Biologi Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Celebes Biodiversitas : Jurnal Sains dan Pendidikan Biologi Jurnal Profesi Medika: Jurnal Kedokteran dan Kesehatan AGROLOGIA : Jurnal Ilmu Budidaya Tanaman Biopendix: Jurnal Biologi, Pendidikan dan Terapan Molucca Medica Jurnal Karya Abdi Masyarakat PAMERI : Pattimura Medical Review Rumphius Pattimura Biological Journal
Nindatu, Maria
Jurusan Biologi Fakultas MIPA Universitas Pattimura Ambon
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Journal : PAMERI : Pattimura Medical Review

 1 
PERBANDINGAN EFEK PEMBERIAN MADU DAN N-ACETYLCYSTEINE TERHADAP GAMBARAN HISTOPATOLOGIS GINJAL MENCIT (Mus musculus) YANG DIBERIKAN PAPARAN ASAP ROKOK Debby Sanders; Maria Nindatu; Marissa Matinahoru
PAMERI Vol 1 No 2 (2019)
Publisher : Fakultas Kedokteran Universitas Pattimura

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (2460.867 KB) | DOI: 10.30598/pamerivol1issue2page71-87

Abstract

Honey is a natural ingredient that contains antioxidants. In addition there are also synthetic antioxidants such as N-Acetylcysteine ​​which can neutralize free radicals and prevent kidney damage.This study aims to compare the effects of honey and N-Acetylcysteine ​​on histopathological features of kidney mice given exposure to cigarette smoke.This study uses true experimental with post test only control group design approach. Samples were grouped randomly into control groups and intervention groups. The intervention group was given honey and N-Acetylcysteine ​​then given exposure to cigarette smoke, then observed the difference using the Kruskal-Wallis test and continued with the Mann-Whitney test. The sample of this study uses mice (Mus musculus) male with a body weight of ± 20-30 gr. The results showed no significant difference, with p> 0.05 (P = 0.749) between Honey and N-Acetylsysteine ​​against renal glomerular atrophy of mice given exposure to cigarette smoke. Furthermore, there was a significant difference with p <0.05 (P = 0.029) between honey and N-Acetylsysteine ​​against renal tubular necrosis of mice given exposure to cigarette smoke.
Co-Authors Abraham Simatupang Adriana Hiariej, Adriana Adrien Jems Akiles Unitly Alien Bastian Amos Killay Camelia Gracia Pattinasarany Deansatya Febrian Wambrauw Debby Sanders Eka Astuty Farah Noya Faustinus Sarbunan Gasperz, Westi C Gratia Mayaut Hosyiana Putri Matauseja Huningkor, Yusuf Hutagalung, Inggrid Kailola, Natalie Laura B. S. Huwae Leny Noya Marissa Matinahoru Martha Kaihena Moniharapon, Debby Nia D. Laratmase Nia Laratmase Noya, Farah Prichilia Daro Rahel Hendrijete de Kock Sanaky, Marliyati Siska Teurupun Stesiana Latuputty Sulfiana , Suyono Lateke Theopilus W Watuguly Titus Frendi Wedilena Uniarti, Anik Yandris Kapuate Yolanda, Denny Yuniasih MJ Taihuttu Yuniasih Taihuttu