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Medfarm: Jurnal Farmasi dan Kesehatan
Published by Akademi Analis Farmasi dan Makanan Sunan Giri Ponorogo
ISSN : 23548487     EISSN : 27159957     DOI : -
Core Subject : Health, Science,
Chemistry Medicine & Pharmacology Public Health
Jurnal MEDFARM merupakan terbitan dari lembaga jurnal dibawah naungan Lembaga Penelitian dan Pengabdian Masyarakat (LP2M) Akademi Analis Farmasi dan Makanan Sunan Giri Ponorogo. Topik atau pembahasan dari Jurnal MEDFARM lebih terfokus pada bidang Farmasi, Obat Tradisional, Makanan, Minuman dan Kesehatan
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 63 Documents
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PRAFORMULASI dan EVALUASI SEDIAAN KAPSUL DARI JAHE MERAH (Zingiber officinale) sebagai ANTIDISMINORHEA Isma Oktadiana
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 11 No 1 (2022): MEDFARM: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v11i1.99

Abstract

Red ginger is a tuber rhizome that grows wild in Indonesian soil and is often used as medicine. This study aims to develop and test red ginger (Zingiber officinale) extract capsules. Red ginger extract (active component), corn starch (filler), Vivapur 101 (adsorbent), Aerosil (absorbent), Talc (glidan), and magnesium stearate are among the constituents in this product (lubricant). The purpose of this study was to develop and test red ginger extract capsules. The results showed that the weight uniformity test for capsule preparations met the criteria for the average weight and did not deviate, and the disintegration time test for capsules met the requirements of less than 15 minutes.
EVALUASI PERSENTASI KESESUAIAN DENGAN PEDOMAN 3 PENGGUNAAN ANTIBIOTIK DAN ANTIVIRUS PADA PASIEN COVID-19 NON VENTILATOR DI RSUD BANGIL Vincentina Yenny Triamyanti; Rika yulia; fauna herawati; Abdul Kadir Jaelani
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 11 No 2 (2022): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v11i2.94

Abstract

Coronavirus (Covid-19) is an infectious disease caused by the SARS-CoV-2 virus. Most people infected with this virus develop mild to moderate respiratory illness and recover without requiring special treatment. However, people who are older and have comorbid will experience severe illness and require medical attention that can lead to death. The aimed of this study was to provide an overview of the evaluation of the use of antibiotics and antivirals in non-ventilated Covid-19 patients at Bangil Hospital. The method used is Defined Daily Dose (DDD/100 patient-days) and One Way ANOVA analysis. Based on the DDD/100 patient-days value, the most widely used antibiotic group was Moxifloxacin and the most common antiviral group was Remdesivir. Meanwhile, based on different tests on the use of antibiotics and antivirals, it is known that there is no significant difference between those who use antibiotics and do not use antibiotics and those who use antivirals without using antivirals. Thus it can be concluded that the use of antibiotics and antivirals has no effect on the patient's recovery rate.
PENGETAHUAN, SIKAP DAN PRAKTIK MASYARAKAT KECAMATAN KINTAMANI TERHADAP PENGGUNAAN OBAT TRADISIONAL Dewi Puspita Apsari; Ni Putu Wintariani
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 11 No 2 (2022): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v11i2.95

Abstract

Background: Complementary Alternative Medicine (CAM) is very popular among people. Nevertheless, an inappropriate combination of CAM and conventional medicine can lead to adverse drug reactions (ADR). This is very limited known by the public. Therefore, it is necessary to conduct research on the knowledge, attitudes, and practices of using CAM in Kintamani District. Methods: This cross-sectional quantitative study was conducted from June to Agustus 2021. The target population in this study was 102 people in Kintamani District who were more than or equal to 18 years old and using CAM maximum of a year before. Descriptive data were processed using SPSS (21.0) to describe the knowledge, attitudes, and practices of CAM. Pearson correlation test was conducted to determine the relationship between demographic characteristics on knowledge and attitudes to use CAM. Results: The level of knowledge Kintamani District regarding the use of CAM is sufficient as many as 71 (69.61%) people. In addition, 95 (93%) people have a positive attitude about using CAM. In practice, 44 (42.3%) people use herbs in the category of CAM that is often used. Information about CAM they got from the family was 37 (29.6%) and was used to treat hypertension as many as 35 (32.8%) respondents. Conclusion: People in Kintamani District, Bangli have sufficient knowledge and a positive attitude towards the use of CAM. In addition, most people use traditional medicine to treat hypertension
COMPARATIVE ANALYSIS OF SERVICE QUALITY BETWEEN PUBLIC AND PRIVATE HOSPITALS, USING SERVQUAL MODEL: A CASE STUDY OF PESHAWAR, PAKISTAN Abdul Rasool Khoso; Farhan Akhtar; Arshad Ali Narejo; Sajjad Ali Mallah; Kainat Vighio; Darya Khan Sanjrani
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 11 No 2 (2022): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v11i2.102

Abstract

Health care industry is the integration and combination of various sectors offering quality and services to treat patients with preventive, curative, rehabilitative and palliative care. The healthcare system of Pakistan faces the challenges in providing quality as well as services as a whole, which is still supposed to be relatively poor to deliver satisfactory health care service to its citizens. Keeping in the view the nature of study, the researcher applied the quantitative method approach for obtaining the appropriate results, furthermore one sample T-test was performed to get the precise consequences of the data. For the particular purpose the SERVQUAL model which consists of five different service quality dimensions distinctively empathy, tangibility, assurance, timeliness, and responsiveness was applied. utilize to determine the local people/patients actual perception about the health care quality delivered by public and private sector hospital in Peshawar, Pakistan. A convenient based sample (n=150) was embraced from five hospital (3 public and 2 private) located in Peshawar. The results of the study identified the quality gaps in the service quality in various dimensions of SERVQUAL model. The result reveals that private hospitals are far better in term of empathy, tangibility, timeliness, and responsiveness, showing big difference between both hospitals. However, there is very little difference between the mean values of the service quality construct ‘assurance’ among the private having mean value (M=3.67; SD=.5258) and public (M=3.10; SD=7415) hospitals. It is because of qualified doctors with high expertise in the field of medicines/surgery and generally serving public hospitals as a permanent employees. Thus the study concluded that private hospitals are far away better from each perspective than the public due to the increasing trend of the resources availability. Since, majority of respondents who avail health care’s from the private hospitals were found satisfied in term of assurance, tangibility, timelines, responsiveness and tangibility as compared to the patients of public hospitals in Peshawar city. Finally the study recommends that, the public hospitals should implement feedback mechanism of its customers to get the actual picture of service quality and any deficiency in service quality should be serious considered for better outcomes. Furthermore government should also introduce value added rewards and facilities for the workforce of public hospitals to motivate them to better health service quality as for the sustainable development and betterment of public sectors
UJI TOKSISITAS AKUT FRAKSI N-HEKSAN BAWANG LANANG HITAM (Allium sativum L.) PADA MENCIT PUTIH JANTAN Nurul Adi Aryani; Eka Wisnu Kusuma
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 11 No 2 (2022): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v11i2.103

Abstract

Bawang lanang hitam ialah tumbuhan yang banyak dipakai jadi obat tradisional maka dibutuhkan guna tahu tingkat keamanannya. Penelitian dilakukan secara eksperimental dengan tujuan untuk mengetahui nilai LD50 dan gejala toksik dari pemberian fraksi n-heksan bawang lanang hitam terhadap mencit putih jantan dengan uji toksisitas akut. Pengamatan dilakukan secara intensif 30 menit, 4 jam pertama setelah perlakuan dan dilanjutkan 24 jam setelah perlakuan dengan dosis oral fraksi n-heksan bawang lanang hitam 2,38 mg/20gBB, 2,97 mg/20gBB dan 3,57 mg/20gBB. Gejala toksik yang diamati meliputi perubahan berat badan, tingkah laku, perubahan warna dan kerontokan bulu, dan feses. Dari hasil pengamatan menunjukkan bahwa fraksi n-heksan bawang lanang hitam tidak menimbulkan efek toksik atau masuk dalam kategori praktis tidak toksik pada hewan uji yang dibuktikan dengan tidak adanya kematian pada hewan uji setelah 24 jam perlakuan.
ANALISIS KELENGKAPAN ADMINISTRASI RESEP NARKOTIKA PADA APOTEK RAWAT JALAN RSI SITI RAHMAH KOTA PADANG SUMATERA BARAT Siska Ferilda; Elsa Marcellinda; Sri Wahyuni; Sandra Tri Juli Fendri
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 11 No 2 (2022): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v11i2.106

Abstract

ABSTRAK: Obat golongan narkotika merupakan salah satu obat yang digunakan sebagai analgetika dan peredarannya harus dengan resep dokter serta pengeluarannya diapotik mesti ada pelaporan. pelayanan resep harus terlebih dahulu dilakukan telaah salah satunya adalah melakukan telaah administratif yang meliputi nama pasien, umur pasien, jenis kelamin pasien, berat badan pasien, nama dokter, nomor SIP dokter, alamat dokter, nomor telepon dokter, paraf dokter dan tanggal resep. Tujuan penelitian ini adalah untuk mengetahui persentase perparameter kelengkapan administratif resep di Apotek rawat jalan RSI Siti Rahmah Padang periode januari – maret 2022 . Penelitian dilakukan di Apotek rawat jalan RSI Siti Rahmah dengan menggunakan metode rancangan penelitian non eksperimental yang bersifat deskriptif analitik. Populasi pada penelitian ini lembar resep narkotika. Hasil penelitian akan menunjukkan resep narkotika pada apotek rawat jalan RSI Siti Rahmah tidak satupun yang lengkap dengan nilai 100% dan resep narkotika yang lengkap pada semua sample dengan nilai 0%. Lembar resep yang memenuhi kelengkapan administratif resep dengan rincian ada nama pasien 100%, umur pasien 84%, jenis kelamin 0%, berat badan 0%, tinggi badan 0%, nama dokter 75%, nomor SIP 48,7%, alamat 86,3%, paraf dokter 27,3%tanggal resep 84,7%, unit asal 50%, nama obat 100%, dosis 100%, jumlah obat 100%, cara penggunaan 99,7%. berdasarkan hasil yang diperoleh didapatkan kelengkapan administrassi yang terpenuhi 100% hanyalah terkait nama pasien, nama obat, dosis dan jumlah obat sedangkan kelngkapan administrasi yang lainnya tidak terpenuhi 100%.
UJI DAYA HAMBAT MADU HUTAN BADUY SEBAGAI SUBSTRAT PADA BUNGA TELANG (Clitoria ternatea L) MELALUI METODE BIOTEKNOLOGI FERMENTASI KOMBUCHA DALAM MENGHAMBAT PERTUMBUHAN BAKTERI PATOGEN Kusumiyati Kusumiyati; Diyan Yunanto Setyaji; M. Fariz Fadillah; Firman Rezaldi
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 11 No 2 (2022): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v11i2.109

Abstract

Telang flower (Clitoria ternatea L) fermented by kombucha is a probiotic drink produced by a consortium of bacteria and yeast. The raw material in this kombucha fermentation is in the form of telang flowers that have been cold from the previous boiling process. This study aims to determine the antibacterial activity of telang flower kombucha with different concentrations of Baduy forest honey. The concentration of Baduy forest honey consisted of 20%, 30%, and 40% (w/v) where each treatment was repeated 3 times. The positive control used in this study was kombucha made from green tea. Sterile aquadest is a treatment positioned as a negative control. The disc diffusion method is one of the methods used in antibacterial testing by measuring the diameter of the inhibition zone. Telang flower kombucha fermentation has activity as a broad-spectrum antibacterial source. This can be indicated by the potential to prevent the growth of Staphylococcus aureus, Staphylococcus epidermidis, Pseudomnonas aeruginosa, and Escherichia coli bacteria. Baduy forest honey concentration of 40% is the best concentration in fermented kombucha flower telang as an antibacterial and has the potential as the latest functional drink from fermented biotechnology products.
REVIEW ARTICLE: ANALISIS KANDUNGAN LOGAM BERAT DENGAN BANTUAN LIGAN ASAM TANAT SECARA SPEKTROFOTOMETRI VISIBLE fawandi fuad alkindi; Reine Risa Risthanti; Merfy Jong
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 11 No 2 (2022): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v11i2.123

Abstract

Limbah adalah bahan buangan yang dapat menurunkan kualitas lingkungan, seperti logam berat. Logam berat yang terakumulasi dalam tubuh manusia secara berlebih dapat membahayakan kesehatan hingga menyebabkan kematian, sehingga perlu dilakukan analisis logam berat. Metode yang digunakan untuk menganalisis logam berat dengan bantuan asam tanat adalah spektrofotometri visible pada berbagai kondisi, akan tetapi litetatur mengenai topik tersebut masih jarang ditemukan di Indonesia. Review article bertujuan untuk menentukan kondisi reaksi optimal kompleks logam dengan asam tanat agar dapat digunakan untuk analisis dengan metode spektrofotometri visible. Pengelompokan data hasil article review ini dapat ditemukan pada berbagai database, seperti Google Scholar, Science Direct, Pubmed, dan SpringerLink. Terdapat kriteria inklusi dalam article review ini adalah artikel yang membahas terkait logam berat yang dapat dideteksi dengan spektrofotometer visibile menggunakan asam tanat dan analisis logam gengan bantuan ligan asam tanat, sedangkan kriteria eksklusinya adalah bentuk artikel review, dan ditemukan hasil penelusuran sebanyak 17 jurnal berdasarkan kriteria inklusi dan eksklusi. Preparasi sampel dapat dilakukan dengan cara mendestruksi basah sampel kemudian menggunakan masking agent jika sampel mengandung lebih dari satu ion. Kondisi reaksi untuk menganalis logam berat dengan asam tanat adalah nilai pH dari asam hingga basa, jenis logam yang dianalisis, dan konsentrasi ligan yang mempengaruhi perubahan warna, rasio konsentrasi dan panjang gelombang kompleks logam-asam tanat. Modifikasi ligan asam tanat juga dapat meningkatkan selektivitas dalam menganalisis logam berat secara spektrofotometri visible.
POTENSI EKSTRAK ETANOL BIJI JINTEN HITAM (NIGELLA SATIVA L.) MENURUNKAN KADAR GLUKOSA DARAH PADA TIKUS PUTIH (Rattus norvegicus) JANTAN KONDISI HIPERGLIKEMIK. Ivan Charles Seran; Agustinus Alfred
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 11 No 2 (2022): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v11i2.126

Abstract

Diabetes mellitus is a disease characterized by elevated blood sugar levels, one of which is often exposed to free radicals. The purpose of this study was to determine the effects of hypoglycemia and ethanol extract on black cumin seeds. This may affect the reduction in blood glucose levels and the increase in weight gain and food intake induced by alloxan in laboratory rats. This study is an experimental laboratory study using only a post-test class design. Subjects of this study were his 30 male Wistar rats who were adjusted for his type 2 diabetes using alloxan induction. The rats he divided into six groups. group II negative control alloxan 150 mg/kg body weight; group III positive control glibenclamide 0.45 mg/kg body weight; kg body weight, Group V black cumin seed ethanol extract dosage 200 mg/kg body weight. The results showed that black seed ethanol extract at doses of 100, 200, and 400 mg/kg body weight reduced blood glucose levels and increased body weight and food intake in experimental rats. The most effective dose is 400 mg/kg body weight.
PENGUJIAN EFEK DIURETIK INFUSA DAUN KOPI (Coffea arabica L.) PADA TIKUS PUTIH JANTAN GALUR WISTAR Suharyanisa Suharyanisa; Jon Kenedy Marpaung; Ivan Elisabeth Purba; Bengi Simahara
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 11 No 2 (2022): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v11i2.139

Abstract

Diuretik bekerja pada ginjal dengan cara meningkatkan eksresi air dan natrium klorida. Kecenderungan masyarakat mengonsumsi diuretik berbahan kimia menyebabkan banyaknya efek negatif yang ditimbulkan. Penggunaan bahan alam sudah banyak diteliti untuk menggantikan obat-obatan kimia. Salah satu bahan alam yang memiliki khasiat yaitu tanaman kopi. Tanaman kopi yang digunakan bagian daunnya mengandung senyawa-senyawa antioksidan (flavonoid, alkaloid, saponin, kafein dan polifenol) yang bermanfaat sebagai anti inflamasi (anti peradangan), anti kanker, diuretik, antimikroba dan aktivitas antioksidan. Infusa Daun Kopi (IDK) diperoleh menggunakan teknik infusa dengan pelarut akuades kemudian digunakan pada 25 ekor tikus yang dibagi menjadi 5 kelompok. Kelompok I (negatif) Na-CMC 0,5 %, kelompok II (positif) Furosemid 3,6 mg/kgBB, kelompok III, IV, V IDK dosis 10, 20, 40% diberikan secara oral. Tikus diberi akuades secara oral dengan dosis 15 ml/kgBB. Tikus di letakkan di dalam kandang metabolik, kemudian pemeriksaan fisik urin dilakukan setiap 1 jam sekali selama 6 jam. Hasil penelitian menunjukkan bahwa IDK dengan dosis terbaik adalah 40% yang memberikan peningkatan volume urin, memberi pengaruh terhadap pH urin, memberi pengaruh terhadap berat jenis urin, memberi pengaruh terhadap warna urin dan memberi pengaruh terhadap kejernihan urin.

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