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Jurnal Insan Farmasi Indonesia
Published by Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin
ISSN : 26213184     EISSN : 26214032     DOI : https://doi.org/10.36387/jifi
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology Physics
Focus and Scope Jurnal Insan Farmasi Indonesia (JIFI) is a broad-based primary journal covering all branches of pharmacy and its sub-disciplines that contains complete research articles, short communication and review articles. JIFI is a forum for the publication of quality and original works that open discussions in the field of pharmacy and health sciences.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 12 Documents
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Search results for , issue "Vol 5 No 2 (2022): Jurnal Insan Farmasi Indonesia" : 12 Documents clear
EVALUASI DRUG RELATED PROBLEMS PENGGUNAAN OBAT ANTIDIABETES PADA PASIEN DIABETES MELITUS TIPE 2 DI INSTALASI FARMASI RAWAT INAP RUMAH SAKIT TK.III DR. R. SOEHARSONO Nazhipah Isnani; Muliyani Muliyani; Muhammad Zaini; Putri Sheila Wardhani
Jurnal Insan Farmasi Indonesia Vol 5 No 2 (2022): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v5i2.920

Abstract

Diabetes mellitus is a disease characterized by hyperglycemia and disturbances of carbohydrate, fat and protein metabolism associated with absolute or relative deficiency of insulin action and/or secretion. The purpose of this study was to determine the characteristics of type 2 DM patients and whether there were DRPs (Drug Related Problems) using antidiabetic drugs in patients with Type 2 Diabetes Mellitus at the Inpatient Pharmacy Installation of Tk.III Hospital Dr. R. Soeharsono period 2019-2020. This research is a non-experimental research with a descriptive research design with a retrospective approach. The sampling technique used was total sampling with a sample of 42 patients taken from the medical records of type 2 DM patients who received antidiabetic drugs at the Inpatient Pharmacy Installation of Tk.III Hospital Dr. R. Soeharsono Banjarmasin. From the results of this study, type 2 diabetes was mostly experienced by women, 25 patients (60%) with an age range of 41-60 years (62%), with the most diabetes complications being hypertension (59.5%). The results of the study of 42 patients studied, there were 22 patients (52.3%) who experienced DRPs by category in a row, namely drug interactions (33.3%), drugs without indications (14%), indications without drugs (4 ,7%), wrong drug (2.4%), under dos
The UJI EFEKTIFITAS GEL KOMBINASI EKSTRAK DAUN BELUNTAS (Pluchea indica L. Less) DAN RIMPANG JAHE MERAH (Zingiber officinale Roscoe) TERHADAP BAKTERI Propionibacterium acne DAN Staphilococcus epidermidis Mindiya Fatmi; Agung Eru Wibowo; Deni Rahmat
Jurnal Insan Farmasi Indonesia Vol 5 No 2 (2022): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v5i2.946

Abstract

Beluntas leaf (Pluchea indica L. Less) and red ginger rhizome (Zingiber officinale Roscoe) is a plan have activity as antibacterial causes acne. Beluntas leaf contain antibacterial compounds from alkaloid, flavonoid free type flavonol, steroid and tannin. Red ginger rhizome extract compounds flavonoid, essential oil, polifenol, and saponin. This study aim to develop gel product extract combination from beluntas extract and red ginger rhizome at concentration 1: 1; 1: 2 and 3:2 formulated in gel, then tested the physical characteristic and gel microbiology tested on P. acne and S. epidermidis. Beluntas leaf and red ginger rhizome extracted by maceration in ethanol 96%, and carbopol 934 as gel base. Physical characteristic test comprise homogeneity, organoleptic, pH, dispersion gel and viscosity. Microbiology tested use method diameter of inhibition zone with Medi-Klin Gel® as positive control. The result show homogeneous gel preparation, with brownish green color, ginger smell, pH 5,83-6,07, spreadability 5,1-5,7 cm, viscosity 690000 cp-1460800 cp. effect of adding extract beluntas leaf and red ginger rhizome to gel preparation, in both single and combination extracts. Antibacterial evaluation showed that formula 3 give the best effectiveness with 5,92 mm zone of inhibition against P. acnes and 4,15 mm against S. epidermidis.
KORELASI ANTARA KADAR GULA DARAH DENGAN KUALITAS HIDUP PASIEN DIABETES MELLITUS DI FASILITAS PELAYANAN KESEHATAN PRIMER Abdul Mahmud Yumassik; Riza Alfian; Akhmad Riski; Soraya Soraya; Welinda Dyah Ayu; Leonov Rianto
Jurnal Insan Farmasi Indonesia Vol 5 No 2 (2022): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v5i2.989

Abstract

Diabetes mellitus is a metabolic symptom caused by an increase in blood glucose due to impaired insulin secretion, insulin resistance, or both. Blood glucose levels above the normal limit have an influence on the quality of life of diabetes mellitus patients. The study was conducted with a cross sectional design. Data collection was carried out prospectively during the period from May to June 2022. The sample in this study was patients with diabetes mellitus in one of the primary health care centers in Banjarmasin City. Quality of life data was collected using the EQ-5D questionnaire, while blood glucose levels data was obtained from medical record patient. A total of 75 samples participated in this study. The results showed that the mean fasting blood sugar level was 162,95 mg/dL. The mean value of the sample's quality of life score based on the EQ-5D index was 0,739. There is a significant correlation between blood glucose levels and the quality of life of patients with diabetes mellitus. The results of the correlation indicated that the lower the blood glucose level of patients with diabetes mellitus, the higher their quality of life.
PERBEDAAN PENURUNAN TEKANAN DARAH PASIEN HIPERTENSI YANG DIBERIKAN TERAPI AMLODIPIN PADA PAGI HARI DAN MALAM HARI DI PUSKESMAS BAYANAN KABUPATEN HULU SUNGAI SELATAN Khalisah; Nurul Mardiati; Lisa Setia; Saidillah
Jurnal Insan Farmasi Indonesia Vol 5 No 2 (2022): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v5i2.1012

Abstract

Research of amlodipine drug therapy time against a decrease in blood pressure showed different results, it had a significant and insignificant effect. Research aimed to identify differences blood pressure reduction hypertension patients who give amlodipine drug therapy in the morning with night at the Puskesmas Bayanan Hulu Sungai Selatan Regency. This research method is obsevasional descriptive with Pre and post test design. There are two groups in this design, namely hypertension patients who give amlodipine drug therapy in the morning and night, blood pressure measured before and after 10 days observation, then compared between the difference in the decrease blood pressure of patients given amlodipine drug therapy in the morning and night. Results of respondents who give amlodipine drug therapy in the morning experienced average decrease in blood for systole -13.67 mmHg and diastole -6.33 mmHg. Amlodipine therapy at night experienced an average decrease in blood for cystole -19 mmHg and diastole -10.33 mmHg. Wilcoxon sigh test results for pressure systole values Asymp.sig. 0.007 and diastole pressure values Asymp.sig. 0.003 or <0.05 which states hypothesis is accepted, or there is a difference between a decrease blood pressure of hypertension patients give amlodipine drug therapy in the morning and night.
EVALUASI PENYIMPANAN SEDIAAN FARMASI DI GUDANG PUSKESMAS SE KOTA BANJARMASIN Amaliyah Wahyuni; Reda; Noor Aisyah; Fitrah Shafran ilahi
Jurnal Insan Farmasi Indonesia Vol 5 No 2 (2022): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v5i2.1056

Abstract

Pengelolaan obat merupakan salah satu kegiatan pelayanan kefarmasian. pengelolaan obat adalah hal penting dan perlu dilakukan dengan baik, karena pengelolaan obat yang baik akan menjamin kelangsungan ketersediaan dan keterjangkauan pelayanan obat yang efektif, efisien dan rasional. Penelitian ini bertujuan untuk mengetahui pengelolaan obat di Puskesmas Kayu Tangi Banjarmasin dan faktor yang menyebabkan ketidaksesuaian. Penelitian ini adalah penelitian deskriftif non eksperimental dilakukan secara prospektif dan retrospektif. Pengumpulan data menggunakan lembar observasi berdasarkan SOP Kefarmasian di Puskesmas. Populasi dan sampel adalah seluruh data pengelolaan obat yang meliputi perencanaan, permintaan, penerimaan, penyimpanan, distribusi, pengendalian, administrasi dan pelaporan di Puskesmas Kayu Tangi Banjarmasin pada bulan Februari – April 2022. Analisis data dilakukan dengan menghitung persentasi kesesuaian. Hasil penelitian menunjukkan 96% kegiatan sudah sesuai yaitu kegiatan perencanaan, permintaan, penerimaan, distribusi, pengendalian, administrasi dan pelaporan. 4% tidak sesuai yaitu meliputi kegiatan penyimpanan. Faktor yang menyebabkan ketidaksesuaian diantaranya penyimpanan obat yang tidak disusun secara alfabetis dan farmakologi karena ruang yang tidak cukup untuk penyimpanan obat tersebut.
UJI STABILITAS FISIK SEDIAAN MASKER GEL PEEL-OFF EKSTRAK ETANOL DAUN KENITU (Chrysophyllum cainito L.) Gina Septiani Agustien; Nitya Nurul Fadilah; Dina Fitri Nusyifa
Jurnal Insan Farmasi Indonesia Vol 5 No 2 (2022): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v5i2.1064

Abstract

Kenitu leaves contain flavonoids which function as antioxidants that can counteract the bad effects of free radicals, the antioxidant effect will be better if formulated in topical dosage forms. One of the topical dosage forms for use on the face is a peel-off gel mask, its use is easy to remove like an elastic membrane. This study aims to determine the physical stability of the peel-off gel mask preparation of kenitu leaves ethanol extract. The research method was experimental by making three peel-off gel mask formulations based on variations in extract concentration, namely F1 (2%), F2 (4%) and F3 (8%). Evaluations were carried out on the physical stability of the preparation, including organoleptic observations, homogeneity, pH, adhesion, dispersibility, drying time of the preparation, and viscosity. The results showed that the physical stability test of the peel-off gel mask preparation of kenitu leaves ethanol extract could be formulated in the form of a peel-off gel mask preparation, and the best mask formula was F1 with an extract concentration of 2%.
REVIEW : STUDI ETNOBOTANI FARMAKOLOGI DAN FITOKIMIA PANDANUS TECTORIUS DI INDONESIA Ardi Rustamsyah; Siti Nuraeni; Faizah Min Fadhlillah; Dani Sujana; Mimin Kusmiyati
Jurnal Insan Farmasi Indonesia Vol 5 No 2 (2022): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v5i2.1080

Abstract

“Pandan Laut” (Pandanus tectorius) pandanaceae family, Pandanus odoratissimus is a synonym for P.tectorius. Pandanus fasicularis Lam is also a synonym of P.tectorius , P.odoratissimus. P.tectorius is a shrub that is still not widely used. P.tectorius is also type of plant from the pandan family that grows wild along the coast. P.tectorius is abundant in South Asia, Tropical Australia. This plant in Indonesia grows wild along the northern coast of Java, the Thousand Islands, Sumatra and other Islands. This review aims to provide information on ethnobotany, pharmacological and phytochemical activities of P.tectorius, using the method of literature study from several studies on ethnobotany, pharmacological and phytochemical activities of P.tectoriu, sea pandanus leaves have the potential as a mat sieve material, the fruit has the potential for antioxidant, cytotoxic, antibacterial, analgesic, antihyperlipidemic, antihyperglycemic, antimicrobial and anti- inflammatory activity
UJI INVIVO AKTIVITAS DIURETIKA EKSTRAK ETANOL 70% DAUN UNGU (Graptophyllum pictum (L) Griff) PADA MENCIT PUTIH JANTAN GALUR WISTAR Recta Olivia Umboro; Dedent Eka Bimmaharyanto; Fitri Apriliany; Iva Rinia Dewi
Jurnal Insan Farmasi Indonesia Vol 5 No 2 (2022): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v5i2.1137

Abstract

Traditionally, daun ungu plant (Graptophyllum pictum (L) Griff) has been known to have pharmacological effects that can help with a variety of health issues. This plant’s flavonoid compounds content is thought to have diuretic activity in this plant is believed to have activity. The purpose of this study is to determine the diuretic activity and optimal dose of etanol extract of 70% daun ungu administered orally to male white mice. This is an experimental study with a completely randomized design (CRD) that includes 1 negative control group (Na.CMC 0.5%), 1 positive control group (furosemide 40 mg) and 3 test groups of 70% daun ungu ethanol extract doses of 10 mg/kg BW, 25 mg/kg BW and 40 mg/kg BW with urine volume test parameters. One-way ANOVA and Kruskal-Wallis statistical test were used to analyze the data. The results showed that one-way ANOVA revealed a P < 0.05 (0.012), and P ≤ 0.05 (0.051) for the Kruskal-Wallis test. It can be concluded that 70% daun ungu etahanol exctract has effective diuretics, with an optimal dose
PENGARUH SUHU PENYEDUHAN TERHADAP EFEK DIURETIK TEH HIJAU PADA MENCIT JANTAN GALUR SWISS Agustina Susilowati; Nur Karim Kusuma Ramadhan
Jurnal Insan Farmasi Indonesia Vol 5 No 2 (2022): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v5i2.1148

Abstract

Tea (Camelia sinensis L.) is a beverage that is familiar to the community and is drunk by brewing it. Green tea contains chemicals such as polyphenols, tannins, steroids and flavonoids. This study aimed to determine the effect of temperature brewing of green tea in the diuretic effect of male swiss strain mice. This research is an experimental study with 25 mice which were divided into five groups, group I (CMC Na 1%), Group II (Furosemide dose 5.2 mg/KgBB), Group III,IV and V (green tea brewed at 50oC,70oC dan 90oC ) with a brewing time of 5-15 minutes. Urine measurements were performed every 1 hour for 6 hours. Data analysis was carried out using the One-Way ANOVA test followed by the LSD test with a 95% confidence level. The results showed that the diuretic effect at a brewing temperature of 50oC was not significantly different (p> 0.05) with the diuretic effect at 70oC but the average volume of urine at 50oC was greater than 70oC. Diuretic effect at temperature 90oC was significantly different (p<0.05) compared to 50oC and 70oC. The diuretic effect of green tea can be optimal, if the brewed at a temperature of 50oC and 70oC for 5-15 minutes.
PENGARUH PEMBERIAN EKSTRAK ETANOL DAUN RAMBUSA (Passiflora foetida Linn) TERHADAP KADAR KREATININ DALAM DARAH TIKUS WISTAR JANTAN Evi Mulyani; Halida Suryadini; Aditama Reyhan
Jurnal Insan Farmasi Indonesia Vol 5 No 2 (2022): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v5i2.1252

Abstract

Rambusa (Passiflora foetida, Linn) is one of the plants that empirically has potential as a medicine that has been used by the people of Central Kalimantan. Rambusa is reported to have many medicinal properties, one of which is anti-diabetic. In addition to its potential as a medicine, the Rambusa plant with its diversity of ingredients also has the potential to be detrimental to the body both at the cellular level and even organs that function vitally such as the kidneys. The aim of the study was to describe the kidney function of Wistar rats after administration of ethanol extract of the leaves of the Rambusa. The method in this study was carried out in vivo in male Wistar rats with serum creatinine (Scr) as a parameter of kidney function. The extract was given orally at doses of 1 mg/kg, 1.5 mg/kg, and 2 mg/kg and 2,5 mg/kgBB, respectively. each group for 7 (seven) days. The results showed that Scr levels were still within normal limits, namely between 0,578-1,128 mg/dl, and there was no significant difference between the control group and the treatment group.

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