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Jurnal Sains dan Kesehatan

jsk
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Published by Universitas Mulawarman

ISSN : 23030267 EISSN : 24076082 DOI : https://doi.org/10.25026/jsk

Core Subject : Health, Science, Agriculture,

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology

Jurnal Sains dan Kesehatan (J. Sains. Kes) (e-ISSN 2407-6082, p-ISSN 2303-0267), is a national journal with ISSN and published four times a year in 2015. In 2016 the publishing frequency changed to twice a year. In 2021 the frequency increased to six times a year. Jurnal Sains dan Kesehatan is published online by the Faculty of Pharmacy, Mulawarman University, Samarinda City, East Kalimantan. Since 2019, the Jurnal Sains dan Kesehatan has been accredited to SINTA. Jurnal Sains dan Kesehatan publishes manuscripts (Original research Article, review articles, and Short communication) on original work, either experimental or theoretical in the following areas: Pharmaceutics, Pharmaceutical Chemistry, Pharmacology & Toxicology, Pharmaceutical Biotechnology & Microbiology, Pharmacy practice & Hospital Pharmacy, Case Study & Full clinical trials, Clinical Pharmacy, Medicine, and other related fields. The purpose of publishing the Jurnal Sains dan Kesehatan is to provide scientific information about the development of science and technology in the field of Science and Health. Lingkup naskah Jurnal Sains dan Kesehatan mencakup bidang ilmu: Kimia Farmasi Biologi Farmasi Farmakologi Teknologi Farmasi dan Farmasetika Farmasi Klinik dan Komunitas Kedokteran dan Bidang ilmu lain yang terkait Tujuan penerbitan Jurnal Sains dan Kesehatan adalah memberikan informasi ilmiah tentang perkembangan ilmu pengetahuan dan teknologi bidang Farmasi dan yang terkait

Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi

Articles 20 Documents

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Search results for , issue "Vol. 4 No. 3 (2022): Jurnal Sains dan Kesehatan (J. Sains Kes.)" : 20 Documents clear

Aktivitas Antiulseratif Berbagai Tanaman Herbal dan Prospek Masa Depan Sebagai Tanaman Budidaya : Anti-ulceritis Activity of Various Herbal Plants and Future Prospects as Cultivated Plants Hafizh Zahra; Rosa Berlina Haridas; Gusnia Meilin Gholam; Aprijal Ghiyas Setiawan
Jurnal Sains dan Kesehatan (J. Sains Kes.) Vol. 4 No. 3 (2022): Jurnal Sains dan Kesehatan (J. Sains Kes.)
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Peptic ulcer disease (PUD) is one of the most common gastrointestinal disorders in individuals aged 20-50 with 1081 cases of death (0.08%) in Indonesia. The main risk factors for PUD include the use of non-steroidal anti-inflammatory drugs, Helicobacter pylori infection, alcohol, smoking, and physical stress. Nowadays, PUD treatment has transformed using secondary metabolites of herbal plants to compete with allopathic treatment adverse effects. Through this systemic review, several herbal plant metabolites from various studies are responsible for gastroprotective, inhibition of certain neurotransmitters, proton pump repression, or different anti-inflammatory effects. The literature search was carried through extensive databases (PubMed, Science Direct, Semantic Scholar, Springer Link, SAGE, and Google Scholar) with keywords linked with PUD. The scope of the data investigated included plant species, groups of metabolites, in vivo application doses, metabolites mechanism of action, and analytical methods.

Prevalensi Malnutrisi Balita di Desa Karimunting, Kec. Sungai Raya, Kab. Bengkayang, Provinsi Kalimantan Barat: Malnutrition Prevalence of Toddler in Karimunting Village, Sungai Raya District, Bengkayang Regency, West Kalimantan Province Intan Aryanti; Rachma Hidana; Yolanda Safitri; M. Ikhsan Jufri; Putrya Hawa; Dwi Monik Purnamasari; Elies Fitriani
Jurnal Sains dan Kesehatan (J. Sains Kes.) Vol. 4 No. 3 (2022): Jurnal Sains dan Kesehatan (J. Sains Kes.)
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Indonesian children are still experiencing a double burden of malnutrition, both in undernutrition and overnutrition. Based on study, there is an intergenerational effect, such as short condition of parents as a child will affect the next generation’s growth and development and will increase the risk of cognitive delay. This result of this study is expected to help and become a reference for local and national governments in order to manage strategies for handling malnutrition and to achieve national health resilience. This research is descriptive cross-sectional study with total sampling. The study used secondary data of 322 children under 5 years old from Sungai Raya District Health Center from July-August 2021, originating from 7 unit health centre (posyandu). The data obtained in the form of age, body weight (BW), body length (BL)/height (BH) and classified according to the WHO curve (W/Age, BH/age, BW/BH) then calculate the Z score. The result showed that children under 5 yo in short and very short stature children were 13% and 19%. Children with overweight and obesity based on BW/BH in this study were 7 % and 5 %. In conclusion, there was a double burden malnutrition which exceeds the national average.

Penentuan Kualitas Madu Ditinjau dari Kadar Sukrosa dengan Metode Luff Schoorl: Determination of Honey Quality in terms of Sucrose Content with the Luff School Method Novriyanti Lubis; Sofi Sofiyani; Effan Cahyati Junaedi
Jurnal Sains dan Kesehatan (J. Sains Kes.) Vol. 4 No. 3 (2022): Jurnal Sains dan Kesehatan (J. Sains Kes.)
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Determining of the quality of honey reviewed from sucrose level with Luff Schoorl method had been done. On this research, 4 samples was taken and obtained from center market in Garut city. The samples were tested quantitatively by luff schoorl method. The principle of this method was iodometry because of iodide ion used as the basis for the determination of sugar levels. The results showed that sucrose level from 4 samples, such as A, B, C, and D honey were of 1.29; 9.12; 13.91; and 5.64% sequentially. These things showed that only A honey samples had sucrose level which corresponds to the rules of standard quality of honey, while the other three samples such as B, C, and D honey had the sucrose level did not match to the rules of standard quality.The quality standard of honey accordance to SNI 01-3545-2004 was ? 5%.

Profil Hematologi Pasien Covid-19 Berdasarkan Beratnya Kasus: Haematology Profile of Covid-19 Patients Based on the Severity of Cases Taureni Hayati; Mirna Albertina Wijaja; Sri Murtiyani Kusumastuti
Jurnal Sains dan Kesehatan (J. Sains Kes.) Vol. 4 No. 3 (2022): Jurnal Sains dan Kesehatan (J. Sains Kes.)
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

This study aims to determine the hematology profile of Covid-19 patients based on the severity of the case. The method used is descriptive. Data collection techniques are patient clinic data, complete patient blood, NRL, and ALC. The results of the study are a) characteristics of COVID-19 patients in weight that cases in women are more than men, b) the absence of the influence of hemoglobin levels in COVID-19 patients, c) hematocrit values do not affect the incidence of COVID-19, d) there is an effect of leukocytes on the symptoms of COVID-19 patients, e) there is no influence of platelets with the incidence of COVID-19, and f) there is an effect of NLR on the symptoms of COVID-19 patients, and g) there is an effect of ALC on the symptoms of COVID-19 patients. The conclusion of this study is a) there are differences in leukocyte, NLR, and ALC profiles in COVID-19 patients, b) there is no difference in hemoglobin, hematocrit, and platelet profiles in the symptoms of COVID-19 patients, and c) there are significant differences in hematological profiles in COVID-19 patients can help classify COVID-19 patients based on the severity of cases.

Karakteristik Fisik Morfologi, pH, dan Waktu Alir Serbuk Serat Ampas Kelapa sebagai Bahan Pengisi Sediaan Farmasi: Physical Characteristics Morphology, pH, and Flow Time of Coconut Pulp Fiber Powder as a Filling Material for Pharmaceutical Preparations Amatullah Syarifah; Tuti Sri Suhesti; Rehana
Jurnal Sains dan Kesehatan (J. Sains Kes.) Vol. 4 No. 3 (2022): Jurnal Sains dan Kesehatan (J. Sains Kes.)
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Utilization of coconut pulp fiber is still low so that it can be used in the pharmaceutical industry. This study aims to determine the physical characteristics of morphology, pH, and flow time of coconut pulp fiber powder as a filler in pharmaceutical preparations. The procedure of this research was started by making coconut pulp fiber powder, morphological characteristic test, pH test, and flow time test. The results of this study are: (1) Morphological characteristics test, coconut pulp fiber powder has a slightly yellowish white color, tasteless, odorless, and roughness of 426-600 m which means it is in accordance with pharmaceutical grade; (2) the pH of the powder is 6.43 which means it is close to neutral; and (3) the flow time test showed a result of 4.73 grams/second, which means the powder can flow well. In conclusion, coconut pulp powder can be used as a filler in pharmaceutical preparations.

Pola Peresepan Antipsikotik Pasien Skizofrenia Di RSJ Mutiara Sukma Provinsi NTB Tahun 2020: Antipsychotic prescribing patterns for Schizophrenia Patients at RSJ Mutiara Sukma NTB Province In 2020 Candra Eka Puspitasari; Ni Made Amelia Ratnata Dewi; Siti Rahmatul Aini; Raisya Hasina; Iman Surya Pratama
Jurnal Sains dan Kesehatan (J. Sains Kes.) Vol. 4 No. 3 (2022): Jurnal Sains dan Kesehatan (J. Sains Kes.)
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Prevalensi skizofrenia di NTB menempati urutan ketiga nasional yaitu mencapai 9,6%. Terapi primer skizofrenia adalah antipsikotik untuk mencegah timbulnya kekambuhan gejala. Penelitian ini bertujuan untuk mengetahui pola peresepan obat antipsikotik pada pasien skizofrenia. Penelitian ini merupakan penelitian non eksperimental dengan analisis data secara deskriptif dan pengambilan data dilakukan secara retrospektif tahun 2020. Data yang digunakan antara lain data penggunaan terapi berdasar data rekam medis. Hasil yang diperoleh menunjukkan bahwa obat yang paling banyak diresepkan adalah golongan atipikal yakni Risperidon (44,32%). Sedangkan untuk peresepan kombinasi terdapat kombinasi terbanyak yakni Risperidon-Klozapin (34 kali atau 47,89%).

Efektivitas Deferasirox pada Pasien Thalasemia Mayor: Artikel Review: Efficacy of Deferasirox for Thalassemia Mayor: Review Article Naksa Garnida Arfie; Bambang Subakti Zulkarnaen; Sudarmanto Sudarmanto
Jurnal Sains dan Kesehatan (J. Sains Kes.) Vol. 4 No. 3 (2022): Jurnal Sains dan Kesehatan (J. Sains Kes.)
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Thalassemia is a heterogeneous grouping of genetic disorders resulting from decreased synthesis of the alpha or beta chains of hemoglobin. Anemia and iron overload are the main causes of morbidity and mortality due to thalassemia disease. Iron chelation has improved the survival and quality of life of patients with thalassemia major. Deferasirox (DFX) was developed as monotherapy for the treatment of transfusion iron overload. Search data in this literature study using an electronic database, namely Science Direct, Pubmed with the keywords thalassemia, deferasirox and efficacy. The search results obtained 1015 articles and 5 articles that matched the inclusion and exclusion criteria. The total patients in this study were 410 people from 5 countries. The results of the review article found that deferasirox was effective in reducing iron in the body as seen from the LIC (Liver Iron Concentration), T2* heart and serum ferritin in patients with thalassemia major.

Pengaruh Penambahan Ekstrak Aloe vera Terhadap Karakteristik Fisik Basis Polietilen Glikol Sediaan Suppositoria: The Effect of Aloe vera Extract Addition to Physical Characteristic of Polyethylene Glycol Suppository Base Mirhansyah Ardana; Wilujeng Cahya Arundina; Sabaniah Indjar Gamma
Jurnal Sains dan Kesehatan (J. Sains Kes.) Vol. 4 No. 3 (2022): Jurnal Sains dan Kesehatan (J. Sains Kes.)
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Ekstrak Aloe vera berpotensi untuk dikembangkan menjadi sediaan suppositoria karena terbukti memiliki aktivitas laksatif. Pada penelitian ini sejumlah ekstrak yang dosisnya telah dikonfersi dicampurkan dengan basis suppositoria polietilen glikol (PEG). Kemudian dilakukan evaluasi karakteristik fisik meliputi kekerasan, disolusi, dan titik leleh terhadap basis dan sediaan suppositoria yang mengandung ekstrak. Hal ini bertujuan untuk melihat pengaruh penambahan ekstrak terhadap karakteristik basis PEG suppositoria yang telah dioptimasi komposisinya, sehingga akan mempermudah formulator untuk melakukan penyesuaian komposisi basis terhadap persyaratan sediaan suppositoria yang baik. Hasil pengujian menunjukan bahwa ekstrak tidak mengubah kekerasan basis suppositoria, tetapi mempengaruhi disolusi dan titik leleh basis. Ekstrak Aloe vera mempercepat disolusi basis dari 37,163 menit menjadi 36,933 menit dan meningkatkan titik leleh basis dari 62,967 °C menjadi 80,467 °C. Dari data yang diperoleh dapat disimpulkan bahwa basis PEG yang ditambahkan ekstrak Aloe vera tidak memerlukan penyesuaikan komposisi karena perubahan yang terjadi masih sesuai dengan persyaratan dan tidak mempengaruhi performa sediaan dalam hal pelepasan zat aktif.

Profil Pengetahuan dan Keyakinan Vaksinasi Covid-19 Aztrazeneca dan Sinovac sebagai Upaya Pencegahan Covid-19 pada Warga Surabaya: Profile of AztraZeneca and Sinovac Covid-19 Vaccination Knowledge and Belief as an Effort to Prevent Covid-19 in Surabaya Ira Purbosari; Muhammad Wahyono
Jurnal Sains dan Kesehatan (J. Sains Kes.) Vol. 4 No. 3 (2022): Jurnal Sains dan Kesehatan (J. Sains Kes.)
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Coronavirus disease infection 2019 (Covid-19) has infected tens of millions of people in a worldwide pandemic. The main cause of COVID-19 is SARS-CoV-2. Prevention of transmission is carried out by vaccination against COVID-19. The absorption capacity of COVID-19 is still low, so an analysis of the knowledge and confidence profile of COVID-19 vaccination in the community is carried out. The main thing from this research is to look at the relationship between knowledge of people's attitudes towards Covid-19 vaccination. The method used for data sampling is analytic observational research with cross sectional method, with 380 Surabaya residents as respondents who were selected by consecutive sampling technique through questionnaire data collection. The population of this study were all residents of Surabaya who had completed the phase I and phase II vaccinations. In this study, using a data collection sheet to record secondary data on AEFI incident sheets from the Surabaya City Health Office and using a survey method through questionnaires distributed to subjects. Data analysis used statistical analysis of logistic test. From the results of the study, as many as 77.8% of the public knew about the COVID-19 vaccine, categorized with a very good score. This high score indicates a high level of public trust. So this is proven by the increasing level of confidence by 83.1%, it is proven that respondents have a positive attitude towards the success of controlling COVID-19. This study shows that there is a 94.7% relationship between knowledge of public attitudes towards Covid-19 vaccination, therefore knowledge and belief need to be carried out to the community so that the intention to carry out COVID-19 vaccination increases, so that it will suppress the rate of virus transmission.

Front Cover, Editorial Information, Table of Content, Author Guideline, Back Cover Journal Editor
Jurnal Sains dan Kesehatan (J. Sains Kes.) Vol. 4 No. 3 (2022): Jurnal Sains dan Kesehatan (J. Sains Kes.)
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

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Contact Name
Rolan Rusli

Contact Email
rolan@farmasi.unmul.ac.id

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+6285222221907

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admin@farmasi.unmul.ac.id

Editorial Address
Gedung Administrasi Fakultas Farmasi Jl. Penajam, Kampus Unmul Gunung Kelua, Kota Samarinda, Kalimantan Timur, Indonesia, 75119

Location
Kota samarinda,

Kalimantan timur

INDONESIA

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Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name Rolan Rusli

Contact Email rolan@farmasi.unmul.ac.id

Phone +6285222221907

Journal Mail Official admin@farmasi.unmul.ac.id

Editorial Address Gedung Administrasi Fakultas Farmasi Jl. Penajam, Kampus Unmul Gunung Kelua, Kota Samarinda, Kalimantan Timur, Indonesia, 75119

Location Kota samarinda, Kalimantan timur INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Contact Name
Rolan Rusli

Contact Email
rolan@farmasi.unmul.ac.id

Phone
+6285222221907

Journal Mail Official
admin@farmasi.unmul.ac.id

Editorial Address
Gedung Administrasi Fakultas Farmasi Jl. Penajam, Kampus Unmul Gunung Kelua, Kota Samarinda, Kalimantan Timur, Indonesia, 75119

Location
Kota samarinda,

Kalimantan timur

INDONESIA