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Jurnal Ilmiah Farmasi Akademi Farmasi Jember

jurnal_ilmiah_farmasi
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Published by Akademi Farmasi Jember

ISSN : 25034707 EISSN : 2615756X DOI : https://doi.org/10.53864/jifakfar

Core Subject : Health,

Medicine & Pharmacology

Jurnal Ilmiah Farmasi Akademi Farmasi Jember merupakan Jurnal yang menampung artikel ilmiah hasil penelitian di seluruh bidang Farmasi, seperti Farmasi Bahan Alam, Kimia Farmasi, Farmasetika, Farmasi Klinis, Farmasi Komunitas, dan bidang farmasi lainnya.

Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)

Articles 70 Documents

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PENGARUH PEMBERIAN METIL PREDNISOLON INJEKSI TERHADAP Rosida, Yulia Rahmawati, Kukuh Judy Hand
JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER 2016: April - Vol.1 No.1
Publisher : AKADEMI FARMASI JEMBER

Methyl Prednisolone Injection is a type of corticosteroid drug with the works being categorized adrenokortikoid, anti-inflammatory and immunosuppressant . The purpose of this study was to determine the effect of Methyl prednisolone injection against dengue patient's recovery. This reseach was conducted in February in which the peak of endemic dengue. This reseach uses posttest design with the method of data collection is done by observation of secondary data, that is Methyl Prednisolone therapy injection of the patient's medical record and performed with the processing and tabulation system diagram and analysis using SPSS. From the 13 dengue patients were sampled study concluded that administration of Methyl Prednisolone injection affect total thrombosis and not affect temperature body of patient's recovery.Keywords : Methyl Prednisolone Injection, Total thrombosis, Temperature body, Dengue Patient’s

PENENTUAN AKTIVITAS ANTIOKSIDAN DAN KADAR FENOL TOTAL PADA EKSTRAK KULIT BUAH PISANG (Musa acuminata Colla) Rosida, Diyan Ajeng RA
JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER 2017: Juli - Vol.2 No.1
Publisher : AKADEMI FARMASI JEMBER

Antioksidan merupakan senyawa yang mampu menghambat oksidasi molekul lain. Tubuh tidak mempunyai sistem pertahanan antioksidatif yang berlebihan, sehingga tubuh membutuhkan antioksidan eksogen. Kekhawatiran terhadap efek samping antioksidan sintetik menjadikan antioksidan alami menjadi alternatif yang dipilih. Flavonoid merupakan senyawa fenolat (hidroksil fenolik) yang mampu bertindak sebagai antioksidan dan umumnya terdapat pada tanaman. Salah satu limbah tanaman yang mempunyai kandungan flavonoid adalah kulit buah pisang (Musa acuminata). Tujuan dari penelitian ini adalah untuk menetapkan kadar flavonoid total dan melakukan pengujian aktivitas antioksidan kulit buah pisang menggunakan diphenyl picryl hydrazil hydrate (DPPH) sebagai radikal bebas. Metode ekstraksi yang digunakan adalah remaserasi dengan pelarut etanol 96%. Penetapan kadar flavonoid total menggunakan katekin sebagai standar dan pengujian DPPH menggunakan metode spetrofotometri. Hasil penelitian menunjukkan kandungan flavonoid total ekstrak etanol kulit buah pisang sebesar 0,79 ± 0,03 %b/b, aktivitas antioksidan tertinggi dalam IC50 terhadap DPPH sebesar 70,41 mg/L.Kata Kunci : kulit buah pisang, flavonoid total, aktivitas antioksidan, IC50

PENGARUH VARIASI KONSENTRASI HPMC SEBAGAI GELLING AGENT TERHADAP SIFAT FISIK GEL ANTIJAMUR EKSTRAK LENGKUAS (Alpinia galanga (L.) Swartz) Mikhania C.E., Agnis Pondinekaria Aditama, Sri Agita Ningrum
JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER 2019: Juli - Vol.3 No.1
Publisher : AKADEMI FARMASI JEMBER

The aim of this research was to know the influence of HPMC variation concentration as gelling agent againts physical properties antifungal extract galangal gel (Alpinia galanga (L) Swartz). Pre-experimental the one shot case study was used as the research design. Gel is formulated into three formulas with various concentration of HPMC 2% (F1), 3% (F2), and 4% (F3). The materials used in this research were galangal extract, propylenglycol, glycerin, methyl paraben, and aquadest. The result showed that the variation concentration of HPMC give influence to physical properties of organoleptic gel (form, smell and colour), viscosity, and spreadibility of gel but did not influence homogeneity and pH of the gel.Keywords: gel, galangal extract, HPMC

PENGARUH VARIASI KONSENTRASI GLISERIN TERHADAP SIFAT FISIK OBAT KUMUR EKSTRAK DAUN BELUNTAS (Pluchea indica L.) MIKHANIA CHRISTININGTYAS ERYANI
JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER Vol 4, No 2 (2021): JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER
Publisher : AKADEMI FARMASI JEMBER

Mouthwash is an aqueous solution used as a cleanser to improve oral health, aesthetics, and breath freshness. The purpose of this study was to determine the effect of variation concentration of glycerin in beluntas leaf extract (Pluchea indica L.) on the physical properties of mouthwash. Extraction was using maceration method with 5000 ml of 96% ethanol as a solvent. Beluntas leaf extract mouthwash was made in 3 formulas with different glycerin concentration which were 10% (F1), 15% (F2) and 20% (F3). Evaluation includes organoleptic, pH and viscosity tests. The organoleptic test of the mouthwash on the three formulations was brown in color, tasted slightly sweet and had a distinctive minty smell. pH of three formulas were 6.16 - 6.20. Data processing using One Way Anova showed that there was no effect of glycerin variations concentration to pH of mouthwash but there was an effect of glycerin variations concentration to the viscosity of mouthwash.

PENGARUH VARIASI KONSENTRASI AMILUM Zea mays (L) SEBAGAI BAHAN PENGHANCUR SECARA GRANULASI BASAH TERHADAP SIFAT FISIK TABLET PARASETAMOL Dewi rashati, Amirul Fauziah
JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER 2017: Juli - Vol.2 No.1
Publisher : AKADEMI FARMASI JEMBER

This research is aims to determine the effect of variation concentration starch Zea mays (L) as disintegration agent in wet granulation to physical characteristics paracetamo. This research used eperimental method by one shot case study. Paracetamol as active ingredient, starch zea mays (L)as desintegrant agent, PVPK30 as binding agent, avicel as filler and Mg stearat as lubricants. The result of SPSS showed significant (p0,05), that means no difference in the three formulation. The first test is weight uniformity show that from column A and B qualify weight requirement range, hardness test. Showed significant (p0,05) that means nodifference in the three formulation. Friability test showed significant (p 0,05) the last is disintegration time test showed that significant (P0,05) no difference in the three formulation. The research of physic characteristic of the tablet showed that hardness test and time test not qualif. Analysis SPSS showed (p0,05) no difference in the three formulation and amilum had no effect on physical test of paracetamol tablet.Keywords: zea mays (L),paracetamol,physicial characteristic

PENGARUH VARIASI KONSENTRASI HPMC SEBAGAI GELLING AGENT TERHADAP SIFAT FISIK GEL ANTINYAMUK DAUN KENIKIR (Tagetes erecta L.) Mikhania C.E., Asa Falahi, Dewi Ratna Sari
JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER 2019: Desember - Vol.3 No.2
Publisher : AKADEMI FARMASI JEMBER

The aim of this research was to understand the influence of HPMC variation concentration to the physical characteristic anti mosquito gel of extract kenikir leaves (Tagetes erecta L.). Pre-experiment the one shot case study was used as the research design. The variation of HPMC concentration were 2%; 2,5% and 3%. The materials used in this research were kenikir leaves extract, propylenglycol, methyl paraben, jasmine oil and aquadest. The result show that the variation concentration of HPMC give influence to physical properties of organoleptic gel (form, colour), pH and viscosity. The variation concentration of HPMC did not influence homogeneity, spreadibility and smell of the gel.Keywords : Kenikir leaves, HPMC, Anti Mosquito Gel.

The Prescription Pattern And Rationality Of Antibiotics Usage In General Surgery Polyclinic Patient At RSD Kalisat In October - December 2020 CHURORI RORIK CAHYONO
JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER Vol 4, No 2 (2021): JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER
Publisher : AKADEMI FARMASI JEMBER

ABSTRACTBackground research: Antibiotics are the most widely used drug class in the world due to the high incidence of bacterial infections. The high use of antibiotics but not balanced with the rational use of antibiotics can have a negative impact, one of which is resistance. Objective: This study was conducted to examine the prescribing pattern and rationale for the use of antibiotics in the Kalisat Jember Hospital. Research method: This study used a descriptive design, data collection was carried out retrospectively which was taken from October to December 2020 at the surgical clinic at the Kalisat Jember area hospital. Result and coclusion: Based on the calculation results, the number of samples used in this study were 263 prescription sheets with antibiotics. From the results of the study, it was found that the most prescribed pattern of antibiotic prescribing was cefixime as many as 165 prescriptions (62.74%) and the most antibiotic preparations prescribed in tablet form were 253 prescriptions (96.20%). From the results of the study, it was also found that the rationality of the use of antibiotics, namely the accuracy of the dose of 100%, the accuracy of the frequency of 99.24% and the accuracy of the duration of 100%.Keywords: Antibiotic, rational, prescription

ANALISIS POLIFENOL EKSTRAK TEH TUBRUK KEMASAN MENGGUNAKAN SPEKTROFOTOMETRI UV-VIS Hadi Barru Hakam Fajar Siddiq, Rizka Del Rizka Della Yunita Dewi, Jati Riyuwani
JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER 2016: Desember - Vol.1 No.2
Publisher : AKADEMI FARMASI JEMBER

The purpose of this research is determine the polyphenol content of brewed tea. Sample were used three sample. Polyphenol compounds of packaged tea were extracted using percolation method with ethanol 70%. Qualitative test were used using FeCl3 reagent and quantitative test polyphenol content were determined using UV-Vis spectrophotometry method with Folin Ciocalteau reagent. Galic acid was used as comparator in this research. The result of qualitative test is all sample of packaged tea containing polyphenol. Polyphenol content sample A, B, and C, with peercolation method were respectively 0,538; 0,554; and 0,470; %b/b.Keyword: packaged tea, polyphenol, percolation, UV-Vis spectrophotometry

AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL 96% KULIT PISANG RAJA (Musa paradisiaca L) TERHADAP Escherichia coli Agnis Pondinekaria Aditama, Rizqiyah Akbar Mauliddah
JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER 2017: Desember - Vol.2 No.2
Publisher : AKADEMI FARMASI JEMBER

Banana peel is a material that can be used as a natural antibacterial because of its secondary metabolites content. The present study aimed to evaluate antibacterial activity of ethanol 96% extracted from banana (Musa paradisiaca L) peel against Escherichia coli. Result of phytochemical screening indicated that banana peel extract has alkaloid, flavonoid (tannin), and saponin compound that can act as antibacterial. Banana peel extract showed antibacterial activity that was proved by clear zone formed around disk paper. Sample of 64% extract concentration had the largest inhibition zone (9.6 mm) compared to sample of 16% and 32% concentration, inhibition zone of which was 4.4 mm and 6.26 respectively. One Way Anova analysis showed that sample of 64% concentration was significantly different from negative control, 16%, and 32% concentration. Nevertheless, there was no significant difference between 16% and 32% concentration.Keywords: Musa paradisiaca L, Escherichia coli, antibacterial

PENGGUNAAN KATALIS MgF2 DALAM SINTESIS SENYAWA TURUNAN AMOKSISILIN Hadi Barru Hakam Fajar Siddiq
JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER Vol 4, No 1 (2021): JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER
Publisher : AKADEMI FARMASI JEMBER

The synthesis of amoxicillin derivatives was carried out by reaction of amoxicillin with p-aminophenol which was catalyzed by MgF2. The aims of this research was to characterize amoxicillin derivatives. The compounds have been characterized by physical and chemical tests including organoleptic test, melting point test, pH test, Rf value test and maximum wavelength test. The results showed that the compounds having physical characteristics including organoleptic was brown powder and bitter taste with 238°C melting point. The chemical characteristic showed that Rf value was about 0.6, a pH was 6,1 and a maximum wavelength was 311 nm.

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Hadi Barru Hakam Fajar Siddiq

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jifakfar@gmail.com

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Lembaga Penelitian dan Pengabdian Masyarakat Akademi Farmasi Jember. Jl. Pangandaran No. 42 Antirogo, Jember

Location
Kab. jember,

Jawa timur

INDONESIA

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Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name Hadi Barru Hakam Fajar Siddiq

Contact Email hakamfajar@gmail.com

Phone +62331338888

Journal Mail Official jifakfar@gmail.com

Editorial Address Lembaga Penelitian dan Pengabdian Masyarakat Akademi Farmasi Jember. Jl. Pangandaran No. 42 Antirogo, Jember

Location Kab. jember, Jawa timur INDONESIA

Abstract

Abstract

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Abstract

Abstract

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Abstract

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Abstract

Contact Name
Hadi Barru Hakam Fajar Siddiq

Contact Email
hakamfajar@gmail.com

Phone
+62331338888

Journal Mail Official
jifakfar@gmail.com

Editorial Address
Lembaga Penelitian dan Pengabdian Masyarakat Akademi Farmasi Jember. Jl. Pangandaran No. 42 Antirogo, Jember

Location
Kab. jember,

Jawa timur

INDONESIA