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Hadi Barru Hakam Fajar Siddiq
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Lembaga Penelitian dan Pengabdian Masyarakat Akademi Farmasi Jember. Jl. Pangandaran No. 42 Antirogo, Jember
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INDONESIA
Jurnal Ilmiah Farmasi Akademi Farmasi Jember
Published by Akademi Farmasi Jember
ISSN : 25034707     EISSN : 2615756X     DOI : https://doi.org/10.53864/jifakfar
Core Subject : Health,
Medicine & Pharmacology
Jurnal Ilmiah Farmasi Akademi Farmasi Jember merupakan Jurnal yang menampung artikel ilmiah hasil penelitian di seluruh bidang Farmasi, seperti Farmasi Bahan Alam, Kimia Farmasi, Farmasetika, Farmasi Klinis, Farmasi Komunitas, dan bidang farmasi lainnya.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 70 Documents
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HUBUNGAN TINGKAT PENGETAHUAN DENGAN TINDAKAN PENCEGAHAN KANKER SERVIKS PASCA PENYULUHAN PADA WANITA USIA SUBUR Farida Anwari, Acivrida Mega Charisma
JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER 2017: Desember - Vol.2 No.2
Publisher : AKADEMI FARMASI JEMBER

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (460.727 KB) | DOI: 10.53864/jifakfar.v2i2.23

Abstract

Cervical cancer is the number one cause of death in Indonesian women. Cervical cancer is a malignant tumor that grows inside the cervix / cervix is the lowest part of the uterus that attaches to the top of the vagina. The high number of cases is due to limited access to screening, treatment and lack of information and services to the disease. This cervical cancer can be detected early by doing pap smaer examination.This study aims to determine the relationship between the knowledge level of cervical cancer and its prevention measures in women of childbearing age in Kabupatn Gresik East Java.Design The research used is descriptive, data collection using questionnaires given to women participants counseling in Gresik district of East Java with the total population of 68 respondents and the number of samples were 53 respondents, the selection of respondents based on age is fertile age (15-46 years), married and sexually active.The result of this research by using chi square test showed that there was no significant correlation between age with cervical cancer prevention at post counseling (ρ = 0.187 α = 0.05), there was a significant correlation between level of knowledge with precancement of cervical cancer at post counseling (ρ = 0.025 α = 0.05).It is hoped that this research can be a reference for health workers in counseling about cervical cancer in women of childbearing age throughout Indonesia, and suggest that people can increase their knowledge about servical cancer and can take precautions by avoiding the risk factors of cervical cancer.Keywords : Knowledge of cervical cancer, cervical cancer risk factor, Prevention of cervical cancer
PERBEDAAN KADAR PROTEIN PADA ASI DAN SUSU FORMULA BAYI USIA 0-6 BULAN Rizki Yuniarti, Hadi Barru Hakam Fajar Siddiq, Siti Nur Azizah
JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER 2019: Juli - Vol.3 No.1
Publisher : AKADEMI FARMASI JEMBER

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53864/jifakfar.v3i1.39

Abstract

Protein is the main nutrient needed at the beginning of life, especially babies, but many things that cause the baby cannot be breastfed by his mother. The alternative is to give cow milk as a substitute for ASI. This study aims to determined the differences in protein levels and what protein levels were found in breast milk and formula cow's milk for children aged 0-6 months in Jember Regency. The kjehdahl method was selected, namely destruction, distillation, and titration to determined protein levels in breast milk and formula milk. From the results of the experiment, it was found that protein levels were 0.28%, 0.36% and 0.17% for formula A, B and ASI milk. The results of the SPSS analysis test using the T test showed a significance value of 0,189 (p0.05). These results indicate that there are no differences in the levels of protein contained in formula milk and breast milk.Keywords: breast milk, formula milk, protein content, kjehdahl method.
ISOLASI DAN KARAKTERISASI BAKTERI SELULOLITIK ASAL JERAMI PADI DI PERSAWAHAN BOGOR BARAT Siti Nur Azizah
JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER 2017: Juli - Vol.2 No.1
Publisher : AKADEMI FARMASI JEMBER

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (607.994 KB) | DOI: 10.53864/jifakfar.v2i1.18

Abstract

Kandungan selulosa pada jerami padi tergolong tinggi yaitu sekitar 35%. Sebagai senyawa yang paling melimpah di dunia, selulosa dari jerami padi dapat digunakan sebagai sumber penghasil bakteri selulolitik yang dapat menghasilkan enzim selulase sebagai katalis yang bermanfaat dalam bidang industri, pertanian dan kesehatan. Tujuan dari penelitian ini adalah untuk mendapatkan isolat bakteri selulolitik asal jerami padi di Desa Kampung Jawa Kelurahan Setigede Kecamatan Bogor Barat dengan cara isolasi dan karakterisasi isolat yang didapat pada medium CMC agar. Hasil isolasi pada media CMC agar diperoleh sebanyak 5 isolat bakteri selulolitik yaitu isolat J1, J2, J3,J4 dan J5. Hasil skring aktivitas selulolik secara semikuantitatif menggunakan metode congo red menunjukkan bahwa isolat J2 memiliki nilai IAE tertinggi yaitu 1,84. Hasil karakterisasi secara fisik yaitu makroskopis dan mikroskopis serta karakterisasi secara biokimia sesuai petunjuk Bergey’s Manual of systematic bacteriology menunjukkan bahwa isolat J2 memiliki kemiripan dengan Bacillus sp.Kata kunci: Bakteri selulolitik, jerami padi, karakterisasi bakteri
AKTIVITAS ANTITUBERKULOSIS EKSTRAK KULTUR CAIR Streptomyces ENDOFIT RIMPANG Kaempferia galanga TERHADAP Mycobacterium tuberculosis RESISTEN Siti Nur Azizah, Mikhania Cristiningtyas Eryani
JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER 2019: Desember - Vol.3 No.2
Publisher : AKADEMI FARMASI JEMBER

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (393.566 KB) | DOI: 10.53864/jifakfar.v3i2.34

Abstract

The objective of this research was to examine the antituberculosis activity of drug resistant stains using liquid culture extracts Streptomyces Kaempferia galanga rhizomes. The endophytes Streptomyces, there were KJ.3A, KJ3B, KJ.4, and KJ.11. Two resistant strain of Mycocacterium tuberculosis were used, there were HE strain which resistant to isoniazid dan etambutol and SR stainswhich resistant to streptomisin and rifampisin. The liquid culture extracts of Streptomyces endophytes was obtained from centrifugation method by growing Streptomyces colony into YMB media Antituberculosis activity was using Lowen-stein Jensen (LJ) methode after incubation for 8 weeks. The result showed that the four liquid culture extracts Streptomyces endophytes have not been able to inhibit the growth of Mycobacterium tuberculosis in both HE and SR strainsKeywods: Antituberculosis, endofit Streptomyces, resistant M. tuberculosis
STABILITAS FISIK EMULGEL MELOKSIKAM MENGGUNAKAN METODE FREEZE THAW ASA FALAHI
JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER Vol 4, No 2 (2021): JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER
Publisher : AKADEMI FARMASI JEMBER

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (451.1 KB) | DOI: 10.53864/jifakfar.v4i2.75

Abstract

Emulgel is a semi-solid preparation, in the form of an emulsion where the viscosity is increased by the addition of the gelling agent. Emulgel can be used for formulations of active substances that are difficult to dissolve in water. Meloxicam is a first-line treatment to treat rheumatoid arthritis and osteoarthritis. The aim of the study was determine the stability of the physical properties of emulgel meloxicam with the Freeze thaw test. The research design used was quasi experimental. In this study there were 2 storage temperatures, the freeze temperature of 4-8oC and thaw temperature of 40-48oC. The treatment was carried out in 3 cycles for 6 days. Physical stability test of organoleptic (color, odor, and dosage form) showed no difference during storage. Physical stability test of homogenity also showed no difference during storage. Physical stability of the emulsion type showed that there was no phase separation in the emulsifying gel during storage. Significance of pH is 0,083 (p 0,05), viscosity is 0,083 (p0,05), and spreadabilityis 0,102 (p 0,05) can be interpreted that the physical stability of pH, viscosity and dispersion power has no significant difference. From all research data, it can be seen that the meloxicam emulgel preparation did notchanges in physical stability after passing 3 cycles.
POTENSI EKSTRAK ETANOL KULIT BUAH PISANG (Musa acuminata Colla) SEBAGAI OBAT LUKA BAKAR TERHADAP TIKUS GALUR WISTAR PENDERITA DIABETES Rosida, Sri Winarsih, Diyan Ajeng R.
JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER 2016: Desember - Vol.1 No.2
Publisher : AKADEMI FARMASI JEMBER

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (164.746 KB) | DOI: 10.53864/jifakfar.v1i2.13

Abstract

Kulit buah pisang merupakan salah satu bahan alami yang dapat digunakan dalam proses penyembuhan luka bakar. Hal ini disebabkan adanya kandungan flavonoid yang memiliki aktivitas antioksidan sehingga dapat mempercepat fase inflamasi dan meningkatkan sintesis kolagen. Tujuan dari penelitian ini membuktikan ekstrak etanol kulit buah pisang (Musa acuminata Colla) dalam proses penyembuhan luka bakar pada tikus galur wistar penderita diabetes. Metode penelitian menggunakan desain pre and post control group. Sebanyak enam belas ekor tikus dibagi menjadi 4 kelompok perlakuan. Kelompok I (kontrol negatif) diberi basis, kelompok II, III dan IV (kelompok perlakuan) diberi ekstrak etanol kulit buah pisang dengan dosis 25%, 50% dan 75%. Sebelum dibuat model luka bakar, tikus diinduksi aloksan dengan dosis 150 mg/kg BB selama tiga hari. Tikus yang digunakan sebagai model luka bakar adalah tikus dengan kadar gula darah diatas 200 mg/dL. Model luas luka bakar sebesar 225 mm2. Pemberian ekstrak kulit buah pisang secara topikal dilakukan tiap hari selama 16 hari. Pengukuran luas luka diamati pada hari ke 4, 8, 12 dan 16. Hasil penelitian menunjukkan bahwa ekstrak kulit buah pisang (Musa acuminata Colla) berpotensi sebagai obat luka bakar pada tikus putih penderita diabetes (p 0,05).Kata Kunci : Musa acuminata, Luka bakar, Diabetes
UJI AKTIVITAS EKSTRAK LABU AIR (Lagenaria siceria) TERHADAP LUKA BAKAR TIKUS JANTAN GALUR WISTAR Holdin Eka Prilia, Rosida
JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER 2017: Desember - Vol.2 No.2
Publisher : AKADEMI FARMASI JEMBER

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (292.286 KB) | DOI: 10.53864/jifakfar.v2i2.29

Abstract

Water pumpkin (Lagenaria siceria) is a useful plant in Indonesian. People used water pumpkin flesh as a drug wound, especially as wound burning. This study was prove the activity of water pumpkin flesh extract as wound burning in male rats Wistar strain. The method in this research used experimental. This study used 25 male rats Wistar strain divided into 5 groups. The positive control group was given bioplacenton, the negative control group was given CMC-Na base gel, the other group was given water pumpkin gel extract at doses 2.5%, 5% and 7.5%. compount of water pumpkin extract are flavonoid and saponin. This compount have activity as a burn medicine in male rats wistar strain. At activity level 2.5% has activity 40,06%, at dose 5% has activity 49,75%, and at dose 7.5% has activity 60,11%. Water pumpkin gel extract at 2.5%, 5%, 7.5% dose had different activity with negative control group with CMC-Na gel base, but no significant difference (sig 0,05) 25%, 50%, 75%.Keyword : Healing burn medicine, Water Pumpkin, and male rats wistar strain.
ANTIBACTERIAL ACTIVITY Streptomyces spp. ENDHOPHYTIC TO Staphylococcus aureus AND Eschericia coli Siti Nur Azizah
JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER Vol 4, No 1 (2021): JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER
Publisher : AKADEMI FARMASI JEMBER

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (455.406 KB) | DOI: 10.53864/jifakfar.v4i1.50

Abstract

The objective of this research was to known antibacterial activity of 4 endhophytic Streptomyces namely Streptomyces griseorubiginosus,   Streptomyces vellosus, Streptomyces diastaticus and Streptomyces griseoruber against Staphylococcus aureus and Eschericia coli and measure the biggest antibacterial activity which is indicate by clear zone diameter. Antibacterial activity by using agar plug diffusion method showed that Streptomyces vellosus has capable to inhibits growth of Staphylococcus aureus but not with Eschericia coli and Streptomyces diastaticus has capable to inhibits growth of Eschericia coli but not with Staphylococcus aureus. The clear zone of  Streptomyces vellosus and          Streptomyces diastaticus are 5,18 mm and 7 mm respectively.                Streptomyces griseoruber and Streptomyces griseorubiginosus can’t grow during isolation.  Keyword: Streptomyces vellosus, Streptomyces diastaticus, agar plug diffusion method
UJI AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL BIJI EDAMAME (Glycin max (L) Merril) DENGAN METODE DPPH Hadi Barru Hakam Fajar Siddiq, Rosida, Erika Fauziah Prabawati
JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER 2016: April - Vol.1 No.1
Publisher : AKADEMI FARMASI JEMBER

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (221.103 KB) | DOI: 10.53864/jifakfar.v1i1.8

Abstract

Antioxidants are compounds that can inhibit oxidation reactions with the free radicals and molecules are highly reactive. According to the previous research, edamame (Glycin max (L)Merril) plant is one of the plants that contains isoflavon compound that serves as an antioxidant. This study aims to determine the antioxidant activity of edamame extracts. This study is an experimental study. Edamame beans extract obtained by remaceration during 24 hours using 96% ethanol. The concentration of edamame beans extract were make different concentration from 90 ppm, 121,3 ppm, 143 ppm, 173,1 ppm. The extract then added with 0,02 g of DPPH free radicals that have been disolved in 100 mL of 96% ethanol. Those solutions were measured at wavelength 516,5 nm by an UV-Vis spectrophotometer. Vitamin C used as positive control. The result of Antioxidant activity of edamame beans extract has IC50value of 177,2 ppm and Vitamin C as a control has a IC50value 0,18 ppm.It means that 177,2 ppm of edamame beans extract classified as low antioxidant.Keywords : edamame beans (Glycin max L Merril, Antioxidant activity, DPPH method
PENGARUH PENAMBAHAN ASAM SITRAT PADA EKSTRAKSI DAUN JATI (Tectona grandis Linn.f.) TERHADAP SIFAT FISIK SEDIAAN SHEER LIPSTICK Mikhania C.E., Kukuh Judy Handojo, Lailatul Fitriyah
JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER 2017: Desember - Vol.2 No.2
Publisher : AKADEMI FARMASI JEMBER

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (275.149 KB) | DOI: 10.53864/jifakfar.v2i2.24

Abstract

The aim of this study was to know the influence of citric acid addition on teak leaf (Tectona grandis Linn.f.) extraction to the physical properties of sheer lipstick. Physical properties of sheer lipstick include organoleptic test and pH test. The result data for organoleptic test of sheer lipstick color using teak leaves extracted with 3% citric acid addition (F1) was yielded pink, 5% (F2) was red and 7% (F3) was dark red. The organoleptic test of the aroma from three formulas has the same particular odor of essence strawberry. Data of pH test result from three formulations of sheer lipstick using teak leaves extracted with 3% citric acid (F1) was 3,867 ± 0,115, 5% (F2) was 3,467 ± 0,208 and 7% (F3) was 3,233 ±0,057. Data analysis of pH using One Way Anova obtained significance value 0,004 (p 0,05) therefore can be interpreted that there was significant difference of pH from all formulation. From the results it can be concluded that the preparation sheer lipstick using teak leaf extract with addition of citric acid 3%, 5% and 7% influence physical properties of color and pH, but didn’t influence odor.Keywords: citric acid, teak leaf, sheer lipstick

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