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Narwanto
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Jember Medical Journal (JMJ)
Published by Universitas Jember
ISSN : -     EISSN : 29630428     DOI : 10.19184
Core Subject : Health, Science,
Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
ember Medical Journal (JMJ) publishes peer-reviewed original articles, case reports and literature review in basic medical research, clinical research, and applied medical science. This journal is published twice (May and November) by Faculty of Medicine Universitas Jember. Articles are original research that needs to be disseminated and written in English or Indonesia. All submitted manuscripts will go through the double-blind peer review and editorial review before being granted with acceptance for publication. Jember Medical Journal was issued for the first time in 2022. JMJ recieved the ISSN 2963-0428 for online version in 2022.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 14 Documents
 1   2 
Resistant Starch Tipe 3 Modified Cassava Flour (MOCAF) Sebagai Prebiotik Pada Tikus Model Diabetes Mellitus Jauhar Firdaus; Elly Nurus Sakinah
Jember Medical Journal Vol. 1 No. 1 (2022)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (587.644 KB) | DOI: 10.19184/jmj.v1i1.149

Abstract

Prebiotik telah dikenal luas memiliki manfaat dalam kesehatan manusia. Sebagai prebiotik alternatif, resistant starch tipe 3 (RS3) memiliki beberapa kelebihan yakni tidak menyebabkan konstipasi maupun diare, RS3 juga menurunkan glukosa darah dan meningkatkan kadar Glucagon Like Peptide-1 (GLP-1) yang memiliki peran utama dalam mekanisme kontrol glukosa darah pada pasien dengan diabetes mellitus (DM). Salah satu bahan yang bisa digunakan sebagai sumber RS3 adalah Modified Cassava Flour (MOCAF). Tujuan dari penelitian ini adalah untuk menganalisis peran RS3 MOCAF sebagai prebiotik alternatif pada tikus diabetes mellitus. Penelitian ini menggunakan hewan coba tikus wistar jantan (Rattus novergicus) model diabetes dengan memberi injeksi streptozotocin (stz) sebanyak 35mg/KgBB secara intraperitoneal. Dilakukan pemeriksaan kadar glukosa darah pada awal penelitian dan setelah induksi stz untuk menentukan kondisi diabetes, dikatakan diabetes jika kadar glukosa darah lebih dari 200mg/dL. Diet RS3 diberikan sebanyak 20 gram/hari selama 4 minggu. Pemberian diet RS3 MOCAF mampu menurunkan kadar glukosa darah puasa dari 494 mg/dL menjadi107 mg/dLdan glukosa darah post prandial dari 526 mg/dL menjadi 96 mg/dL. Analisis mikrobiologi menunjukkan bahwa bakteri yang paling banyak tumbuh pada pemberian diet RS3 MOCAF adalah Lactobacillus Sp. RS3 MOCAF memiliki peran sebagai prebiotik dan mampu menurunkan kadar glukosa darah pada tikus model diabetes melitus.
Effectivity of Pyridoxine as Adjuvant Therapy of Phenytoin in Patients with Epilepsy at Soebandi Regional Hospital Jember Yovita Karina Pandan Putri; Cholis Abrori; Komang Yunita Wiryaning Putri
Jember Medical Journal Vol. 1 No. 1 (2022)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (548.189 KB) | DOI: 10.19184/jmj.v1i1.150

Abstract

Phenytoin is an antiepileptic drug  used as monotherapy for partial and generalized tonic-clonic seizures for more than 50 years. Pyridoxine is a water-soluble vitamin widely used for seizure patients  unresponsive to standard treatment regimens. This study was conducted to determine the effect of pyridoxine as adjuvant therapy in epilepsy patients receiving phenytoin and to determine the relationship between age, gender, type of epilepsy, and duration of therapy on the incidence of seizures in epilepsy patients at Soebandi Regional Hospital Jember. This research is an observational analytic study with a cross sectional design. The data was taken from the patient's medical record at Soebandi Hospital Jember. The number of samples in each treatment group was 18 samples so the total number of samples in this study was 36 samples. Samples were taken using total sampling technique. Data analysis was performed using Chi-Square  test on bivariate analysis and The Logistic test on multivariate analysis. The sample in this study was dominated by male patients (52.8%), aged 19-59 years (52.8%), had epilepsy with generalized seizure type (86.1%), and received therapy for < 3 years (77.8%). The results of bivariate and multivariate analysis showed correlation between the administration of pyridoxine and the incidence of seizures, indicating that phenytoin therapy with pyridoxine adjuvants was more effective than monotherapy phenytoin. Other factors such as gender, age, type of epilepsy, and duration of therapy were not proven to have a correlation  with the incidence of seizures in epilepsy patients at Soebandi Hospital Jember.        
Sinonasal Bone Destruction caused by Frontal Meningioma Invasion related with Respiratory Tract Infection Incident: A Case Report Novan Krisno Adji; Komang Yunita Wiryaning Putri; Laksmi Indreswari; Muhammad Yuda Nugraha
Jember Medical Journal Vol. 1 No. 1 (2022)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (766.779 KB) | DOI: 10.19184/jmj.v1i1.151

Abstract

Meningioma is uncommonly found in extracranial. Extracranial meningioma can be extension from primary intracranial tumors that accompany osteolytic changes in the skull or causes bone destruction. In this article, we report about intracranial meningioma in the frontal region that extend to the sinonasal bone causes bone destruction and being predisposing factor for respiratory tract infection. A 47-years old female brought to the emergency department due to dyspnea and fever since a week ago and there was found a lump in the frontal region. During the surgical procedure, there was invasion of tumor and caused sinonasal bone destruction. The endotracheal tube (ETT) can be seen from the surgical field. In this case the patient was threated pneumonia infection, it can be related as complication of sinonasal bone destruction that caused by invasion of meningioma to extracranial manifestation. The clinical important that must be informed to the patient the possibility of recurrent respiratory tract infection incidents.
Analisis Kualitatif Refleksi Diri Dokter Muda tentang Pembelajaran pada Stase Psikiatri di Fakultas Kedokteran Universitas Jember/RSD Dr. Soebandi Jember Inke Kusumastuti; Justina Evy Tyaswati; Alif Mardijana
Jember Medical Journal Vol. 1 No. 1 (2022)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (638.156 KB) | DOI: 10.19184/jmj.v1i1.153

Abstract

Rotasi klinik di bagian Psikiatri dapat memberikan tantangan berbeda bagi dokter muda (DM) yang nantinya dapat memengaruhi proses dan hasil pembelajaran serta pandangan mereka terhadap psikiatri. Penelitian ini bertujuan untuk mengeksplorasi pengalaman pembelajaran selama stase psikiatri pada dokter muda. Analisis dilakukan terhadap naskah refleksi diri yang dituliskan dokter muda Fakultas Kedokteran Universitas Jember (FK UNEJ) yang telah menyelesaikan stase psikiatri di RSD Dr. Soebandi Jember pada bulan Juli 2019-Juni 2021. Naskah dianalisis secara tematik untuk mendapatkan beberapa tema. Didapatkan 102 naskah refleksi diri yang ditulis oleh 27 DM laki-laki dan 74 perempuan. DM memiliki pandangan yang berbeda-beda terkait anggapan awal terhadap psikiatri/rotasi klinik di bagian psikiatri serta hal-hal yang dipelajari selama pelaksanaan stase baik secara personal maupun . Meskipun secara umum DM menganggap pelaksanaan stase sudah berlangsung baik, mereka berharap agar pembelajaran bisa dilakukan pada latar yang lebih variatif dan dilakukan secara lebih aplikatif. Peneliti selanjutnya dapat memfokuskan pembahasan pada topik tertentu dan melakukan kajian kualitatif secara lebih mendalam atau menggunakan metode kuantitatif dengan jumlah sampel lebih besar untuk meningkatkan kekuatan dan generalizability penelitian.    
Physical Water Quality and Intestinal Protozoa Contamination on Household Water in Ajung District, Jember Regency Dicky Setiawan; Wiwien Sugih Utami; Laksmi Indreswari; Yunita Armiyanti; Bagus Hermansyah
Jember Medical Journal Vol. 1 No. 1 (2022)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (640.261 KB) | DOI: 10.19184/jmj.v1i1.155

Abstract

Intestinal protozoa infections are still a major health problem in worldwide. The prevalence of intestinal protozoa infections are relatively high in countries facing lack of safe drinking water and lack of suitable sanitation facilities. Lack of sanitation facilities, open defecation, and contamination of environmental feces can make water quality worse, both in terms of physically, chemically, and biologically. Physical water quality is poor when the household water used daily does not meet the standard parameters of the physical water quality standard. The purpose of this study was to determine the relationship between physical water quality and intestinal protozoa contamination in household water in Ajung District, Jember Regency. This type of research is an observational analytic study with a cross sectional research design. The research method used is the correlation method, namely the relationship between physical water quality and intestinal protozoa contamination in household water. The population in this study is household water in Ajung District, Jember Regency. Data analysis consisted of univariate analysis to see the distribution and percentage of temperature, total dissolves solid, color, odor, and intestinal protozoa contamination in household water, and then bivariate analysis using the Chi-square test to analyze physical water quality and intestinal protozoa contamination. The conclusion is there is a relationship between physical water quality and intestinal protozoa contamination in household water.
Hubungan antara Infeksi COVID-19 dengan Preeklamsia pada Ibu Hamil Dita Diana Parti; Elly Nurus Sakinah; Cindy Meylania Pradana; Ricky Roosdiana Dewi
Jember Medical Journal Vol. 1 No. 1 (2022)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (617.077 KB) | DOI: 10.19184/jmj.v1i1.157

Abstract

Ibu hamil ialah kelompok yang rentan terinfeksi COVID-19 akibat adanya perubahan fisiologis di masa kehamilan dan cenderung mempunyai kondisi klinis yang lebih buruk. Berdasarkan penelitian sebelumnya, ibu hamil dengan COVID-19 yang parah berisiko mengalami preeklamsia 5 kali lipat dibandingkan ibu hamil dengan COVID-19 tanpa gejala. Identifikasi hubungan infeksi COVID-19 dengan preeklamsia pada ibu hamil sangat penting dilakukan untuk membantu menentukan langkah penanganan yang tepat. Penelitian ini ditulis menggunakan metode literature review. Sumber pustaka atau data yang digunakan dalam penelitian ini didapatkan dari publikasi ilmiah baik internasional maupun nasional yang tercantum dalam Pubmed, Science Direct, dan Google Scholar dengan kata kunci “COVID-19, preeclampsia, SARS-CoV-2, angiotensin converting enzyme (ACE2), renin-angiotensin system (RAS)”. Review dilakukan terhadap 16 jurnal internasional dan 4 jurnal nasional. Infeksi COVID-19 berhubungan dengan kejadian preeklampsia. Risiko preeklamsia pada ibu hamil dengan COVID-19 meningkat sebanding dengan derajat keparahan COVID-19 yang diderita. COVID-19 dapat menyebabkan preeklamsia melalui beberapa mekanisme, yakni melalui disfungsi endotel, peningkatan kaskade koagulasi, dan peningkatan respon inflamasi. Infeksi COVID-19 dapat memicu terjadinya down-regulasi pada Renin-Angiotensin System (RAS) akibat pengikatan SARS-CoV-2 pada reseptor ACE2. Kondisi ini dapat mengakibatkan terjadinya disfungsi endotel yang nantinya menyebabkan preeklamsia. Infeksi COVID-19 dapat memicu terjadinya preeklamsia melalui peningkatan aktivitas kaskade koagulasi, yaitu perubahan pada PT (prothrombin time), BT (bleeding time), aPTT (activated Partial Thromboplastin Time), dan CT (clotting time). Infeksi COVID-19 juga diketahui dapat meningkatkan respon inflamasi yang ditandai adanya peningkatan nilai pada CRP (C-reactive protein), D-dimer, dan NLR (neutrophil lymphocyte ratio) yang pada akhirnya juga memicu terjadinya preeklamsia.
Lokasi Lesi Sistem Saraf Pusat pada Pemeriksaan Magnetic Resonance Imaging Pasien Covid-19 dengan Stroke: Tinjauan Naratif Moh. Nur Indra Caesar; Muhammad Ihwan Narwanto; Jauhar Firdaus
Jember Medical Journal Vol. 1 No. 1 (2022)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (565.169 KB) | DOI: 10.19184/jmj.v1i1.198

Abstract

Stroke dengan infeksi SARS-CoV-2 merupakan komplikasi penyakit yang serius. Fakta menunjukkan bahwa stroke memiliki persentase kematian sebesar 49%, sehingga stroke dengan infeksi SARS-CoV-2 memiliki risiko kematian yang lebih tinggi dengan manifestasi penyakit yang lebih parah. Tujuan dari penelitian ini adalah untuk mengetahui lokasi pemeriksaan lesi pasien stroke dengan COVID-19 menggunakan Magnitude Resonance Imaging (MRI). Metode penelitian yang digunakan adalah penelitian deskriptif analitik dengan menggunakan tinjauan literatur. Sumber data pada penelitian tinjauan literatur ini diambil dari artikel penelitian nasional dan internasional dengan menggunakan basis data PubMed, Science Direct, Cochrane Library, dan Portal Garuda. Hasil dari penelitian ini didapatkan 24 artikel yang memenuhi kriteria inklusi sebagai sampel. Data yang diekstraksi menunjukkan bahwa lokasi anatomi lesi sistem saraf pusat pada pasien stroke dengan infeksi SARS-CoV-2 yaitu pada cerebrum, cerebellum dan ganglia basalis. Lokasi lesi pada otak besar paling sering ditemukan di lobus frontal dan parietal, diikuti oleh lobus temporal. Dari penelitian ini dengan menggunakan metode tinjauan literatur didapatkan gambaran lesi hiperintensitas melalui pemeriksaan MRI dengan berbagai lokasi lesi mulai dari lobus frontalis, parietalis, temporalis, occipitalis, insula, dan basal ganglia, serta cerebellum. Munculnya lesi pada pasien stroke dengan COVID diduga akibat hiperkoagulabilitas yang menyebabkan tromboemboli dan pada pemeriksaan MRI tampak adanya gambaran lesi hiperintensitas.
Evaluation of Pain after Laminectomy Fusion with Fentanyl Transdermal Patch and Paracetamol Infusion: Case Report Taufiq Gemawan; Adelia Handoko; Aris Prasetyo; Saski Yasmin Alfina; Eprila Darma Sari; Lida Hutami Putri; Aprilia Tiyan Fatmawati
Jember Medical Journal Vol. 1 No. 1 (2022)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (653.774 KB) | DOI: 10.19184/jmj.v1i1.199

Abstract

Pain can occur due to many things, one of which is trauma and surgical procedures. Fentanyl transdermal patch and paracetamol are analgesics that can be used as alternatives to control the pain. The use of the fentanyl transdermal patch is easy to use because it is needle free, the duration of use can be up to 72 hours, and it is used for chronic with moderate to severe intensity. Paracetamol is also an NSAID that is easy to find and often used. The following is a case series regarding three patients with a diagnosis of Lumbar Tumor at L4-L5 vertebrae, Spinal Cord Injury at C6-C7 vertebrae, Canal Stenosis at L4-S1 vertebrae who received a laminectomy fusion procedure. The three patients received fentanyl transdermal patch and paracetamol therapy as postoperative management. Almost all patients reported a decrease in pain scale after using fentanyl transdermal patch and paracetamol, monitoring pain using the Number Pain Rating Scale (NPRS) and Behavioral Pain Rating Scale (BPS) at the 6th, 12th, 24th and 48th hours postoperatively. Differences can occur due to internal and external factors. In this case, most patients felt a decrease in pain scale at 12 and 24 hours after receiving fentanyl transdermal patch and paracetamol therapy, so that it can be used as an option for postoperative pain management.
Risk Factors of Cryptosporidium spp. Infection Through Drinking Water Sources in Farming Communities in Sukowono District Jember Regency Muhamad Dwi Eka Putra; Wiwien Sugih Utami; Dini Agustina; Bagus Hermansyah; Irawan Fajar Kusuma
Jember Medical Journal Vol. 2 No. 1 (2023)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (430.767 KB) | DOI: 10.19184/jmj.v2i1.204

Abstract

Cryptosporidiosis is a zoonotic, emerging water-borne and protozoan disease. This parasite infects the digestive and respiratory tracts of human and various animals. This study aims to determine the risk factors of Cryptosporidium spp. infection through drinking water sources in farming communities in Sukowono District, Jember Regency and using an observational analytic study with a cross-sectional approach. The research sample was reviewed using observational sheets and stool samples with concentration method and using modified Ziehl-Neelsen staining on research subjects’ samples based on inclusion and exclusion criteria totaling 52 people. The results of this study indicate the characteristics of the research subjects in Sukowono District, Jember Regency, dominated by female gender (57.7%), adult age category (42.3%), elementary school graduate (53.8%), and identified as a farmer or rancher (34.6%). The examination of stool samples showed Cryptosporidium spp. an infestation in 1 (one) person. The results of the bivariate analysis using the Fisher's Exact alternative test obtained p of 0.601 (p>0.05). The conclusion is that the majority of research subjects use unhealthy well water as drinking water source, there is one person infected, also all factors from drinking water sources are not at risk of this parasitic infection in Sukowono District, Jember Regency.
Relation between Hypertension Knowledge and Behavior with Blood Pressure on Hypertensive Farm Workers in Mumbulsari Public Health Center Working Area Alyssandra Afqorina Agung; Yuli Hermansyah; Angga Mardro Raharjo; Jauhar Firdaus; Pipiet Wulandari
Jember Medical Journal Vol. 2 No. 1 (2023)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (801.101 KB) | DOI: 10.19184/jmj.v2i1.283

Abstract

The prevalence of hypertension in Indonesia is still relatively high. One of them is hypertension experienced by people who work as farm workers. The high prevalence of hypertension can be caused by the lack of knowledge and behavior of farm workers regarding hypertension. Knowledge about hypertension affects the formation of hypertension control behavior so that it has an impact on blood pressure values. The purpose of this study was to determine the relationship between knowledge and behavior about hypertension with the blood pressure of hypertensive farm workers in the work area of the Mumbulsari Jember Health Center. This study used subjects of agricultural workers who had hypertension in the working area of the Mumbulsari Jember Health Center. The study was conducted by measuring the subject's knowledge about hypertension using the Hypertension Knowledge-Level Scale (HK-LS) questionnaire, the subject's behavior regarding hypertension using the High Blood Pressure – Self Care Profile – Behavior Scale (HBP-SCP-BS) questionnaire, and blood pressure using a digital sphygmomanometer. The results of the study obtained included the majority of subjects had knowledge with sufficient category of 61.90%, behavior with sufficient category of 57.14%, and blood pressure with stage 1 hypertension category of 47.61%. Bivariate analysis with the Mann-Whitney test did not show a significant association between knowledge and blood pressure, but there was a significant relationship between behavior and blood pressure.

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