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Jurnal Kedokteran Diponegoro
Published by Universitas Diponegoro
ISSN : -     EISSN : 25408844     DOI : -
Core Subject : Health,
Medicine & Pharmacology
JKD : JURNAL KEDOKTERAN DIPONEGORO ( ISSN : 2540-8844 ) adalah jurnal yang berisi tentang artikel bidang kedokteran dan kesehatan karya civitas akademika dari Program Studi Kedokteran Umum, Fakultas Kedokteran, Universitas Diponegoro Semarang dan peneliti dari luar yang membutuhkan publikasi . JURNAL KEDOKTERAN DIPONEGORO terbit empat kali per tahun. JURNAL KEDOKTERAN DIPONEGORO diterbitkan oleh Program Studi Kedokteran Umum, Fakultas Kedokteran, Universitas Diponegoro Semarang.
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Articles 8 Documents
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Search results for , issue "Vol 11, No 6 (2022): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)" : 8 Documents clear
Patient With RHD Ec MR Severe, MS Moderate And Trombus In LV, When We Do The Surgeom In Cut Meutia Regional General Hospital Yuri Savitri; Helma Humairah; Jauza Raudhatul Jannah Mendrofa; Nurul Afni; Della Vega Nisha Ayuna
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 11, No 6 (2022): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v11i6.35993

Abstract

Rheumatic heart disease (RHD) is damage of the heart valves due to acute rheumatic fever (ARF) which results from the body’s autoimmune response to Streptococcus pyogenes (group A Streptococcus bacteria) infection which is a throat infection. Acute rheumatic fever is one of the most important causes of cardiovascular morbidity and mortality in the developing countries. A 25-years-old male patient, domiciled in Alue Dalam, Darul Aman, East Aceh, admitted to emergency department of Cut Mutia hospital, the patient was brought to the hospital by his family at 05.0o pm on January 27th, 2022. Patient referred from Graha Bunda hospital. Patient was admitted to the hospital with complaints shortness of breath. Shortness of breath is felt during activity and worsens at night. Shortness of breath since yesterday. The patient also complained of pounding. The pounding has been felt for five days before arriving at the hospital. The patient also has chest pain, and tired easily. Past medical history such hypertension and diabetes mellitus are denied. Physical examination before treatment was obtained: the patient looked restless, weakness, and akker. Echocardiography examination showed the MR Severe, MS moderate, AR moderate, TR moderate, PH mild, AML calsification, all chamber dilatation, and thrombus LV. The patient was given initial treatment in Cut Mutia General Hospital.
Relationship Between Physical Activity During COVID-19 Pandemic and Depression Rates in College Students: Analytical Observational Studies among First Year Medical Students at Universitas Diponegoro Semarang Salafudin Salafudin; Innawati Jusup; Endang Kumaidah; Lusiana Batubara
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 11, No 6 (2022): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jkd (dmj).v11i6.36250

Abstract

Background: The COVID-19 pandemic has an impact on every individual. Lifestyle changes and reduced physical activity are some of them. Less physical activity will affect a person's psychological problems, one of which is depression. Depression is a common mental disorder with depressed mood, loss of interest or pleasure, decreased energy, feelings of guilt or low self-esteem, sleep or appetite disorders, and reduced concentration. Aim: Determine the relationship of physical activity during the COVID-19 pandemic with the level of depression in first-year students of the Faculty of Medicine, Diponegoro University. Methods: The research design is observational analytics with a cross-sectional approach. The study used the International Physical Activity Questionnaire (IPAQ) and Beck Depression Inventory-II (BDI-II), presented in the google form and disseminated through social media. Respondents filled out one hundred seventy-six questionnaires. The purposive sampling method obtained respondents included in the inclusion and exclusion criteria as many as 114 respondents. The data were tested with the Chi-Square test to assess correlations between variables. Results: We found a significant association between physical activity during the COVID-19 pandemic and depression rates (p=0.043). There is a link between sex and physical activity and depression levels (p=0.007), and there is a significant association between age and physical activity and depression levels during the COVID-19 pandemic (p=0.00).
Effect of Plum Fruit Extract (Prunus Domestica L) on Hepar Histology in Male Wistar Rats (Rattus Norvegicus) Induced Alloxan Ganesha Aji Pratama; Indah Saraswati; Desy Armalina; Puspita Kusuma Dewi
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 11, No 6 (2022): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jkd (dmj).v11i6.36243

Abstract

Background: The condition of blood glucose levels exceeding normal limits is hyperglycemia. Hyperglycemia can lead to complications in organs. Glucose levels that exceed normal limits can be reduced by chemical drugs but have side effects such as hypoglycemia and hepar damage. Therefore, the public needs safe alternative treatment with minimal side effects. Consuming fruit is an alternative treatment for plums. Plums contain flavonoids that can increase adiponectin levels which play an important role in regulating blood glucose levels. Researchers are interested in conducting this study because there has been no research on the influence of plums on hyperglycemia. Objective: Analyzing the effect of giving plum (Prunus domestica L) extract on hepar histology of male Wistar rats (Rattus norvegicus) hyperglycemic with alloxan induction. Method: The type of research is experimental, with a posttest design and only a control group design. Total of 35 Wistar were divided into five groups i.e., negative control (K-) was given aquadest, positive control (K+) and treatment group induced with intraperitoneal alloxan 150 mg/kgBW/day, treatment group 1 (KP 1), treatment group 2 (KP 2), treatment group 3 (KP 3) given peroral 100, 200, 300 mg/kgBW/day plum extract. Days 0, 3, 7 and 14 measure blood glucose levels. On the 14th day the Wistar was dissected and made a preparatory block followed by hematoxylin-eosin staining. Observations were conducted under the microscope with magnification of 100x and or 400x and assessed necrosis on hepar using Mordue scores. Result: The group that was given plum extract after being given Alloxan (KP 1, KP 2, and KP 3) had significant differences from the group given only Alloxan (K+), which means the administration of plum extract can suppress blood sugar levels and lower the necrosis rate of hepar rats. Conclusion: Blood sugar levels and necrosis rates in the rat group with the administration of the plum extract at a dose of 300 mg/kgBW/day were lower than doses of 100 mg/kgBW/day and 200 mg/kgBW/day.
Bibliometric Analysis of Publication on Protein Nanoparticle Using VOSviewer Riska Kurnelia Ananda; Asep Bayu Dani Nandiyanto
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 11, No 6 (2022): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v11i6.35942

Abstract

Background: A Study to determine the development of research can be done by bibliometric analysis technique. There are many studies that have been carried out on bibliometric analysis. However, research on bibliometric analysis of published data in the field of protein nanoparticles that has been carried out specifically to determine research development has not been carried out. Objective: This study aims to examine the development of protein nanoparticle research through a bibliometric approach. Methods: The article data was obtained from the Google Scholar database using the publish or perish reference manager software. The keyword "Protein Nanoparticles" is used with a publication time span from 2012 to 2022. Data processing uses Microsoft Excel. Computational mapping using VOSviewer. Results: The article data obtained and considered relevant were 390 articles. The results of the analysis of the development of protein nanoparticle publications in the last 10 years show quite frequent fluctuations. Research fluctuations occurred in 2012 to 2020. There was a decline in 2020-2022 from 35 in 2020 to 19 in 2022. In 2012 and 2014 research on protein nanoparticles became popular, with 47 studies each. Conclusion: Based on the results of mapping the collected article data, it can be seen that the keyword protein nanoparticles is still rarely used in research. It can be concluded that the field of protein nanoparticles is still very likely to be researched and associated with other terms, this will have a higher impact on the novelty of the research.
Mat Pilates Exercise Increase Hip Flexibility in Young Adults with Obesity Naufal Prima Wianto; Erna Setiawati; Dwi Pudjonarko; Tanti Ajoe Kesoema
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 11, No 6 (2022): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jkd (dmj).v11i6.32278

Abstract

Background:Young adult with obesity may experience in decreased hip flexibility. Decreased hip flexibility can be caused by excessive fat mass around the joint, lack of physical activity, resulting in muscle stiffness. Flexibility can be improved by Mat Pilates exercises which combined static and dynamic movements. Objective:To prove increasing hip joint flexibility of young adult with obesity after doing Mat PilatesMethods:This study used experimental study with comparison group pre-test and post-test design. The participants were 38 young adults with obesity lived in Semarang selected by purposive sampling technique. The participants were divided into experiment group and control group. The experiment group was instructed to do Mat Pilates (3 times a week) for 4 weeks and the control group was instructed to do their usual activity. The hip flexibility was measured with sideward leg splits before and after experiment. The collected data was analyzed using paired t, independent t test.Results:There was a significant increase in the value of sideward leg splits after doing Mat Pilates (p < 0,05), from 98,46±9,73 to 112,82±11,22 for left sideward leg splits and from 99,63±10,20 to 111,39±12,99 for right sideward leg splits. The increase in the value of sideward leg splits in the experiment group was higher than the control group (p < 0,05). It was occured for both left sideward leg splits and right sideward leg splits.Conclusion:Mat Pilates increased hip joint flexibility of young adult with obesityBackground:Young adult with obesity may experience in decreased hip flexibility. Decreased hip flexibility can be caused by excessive fat mass around the joint, lack of physical activity, resulting in muscle stiffness. Flexibility can be improved by Mat Pilates exercises which combined static and dynamic movements. Objective:To prove increasing hip joint flexibility of young adult with obesity after doing Mat PilatesMethods:This study used experimental study with comparison group pre-test and post-test design. The participants were 38 young adults with obesity lived in Semarang selected by purposive sampling technique. The participants were divided into experiment group and control group. The experiment group was instructed to do Mat Pilates (3 times a week) for 4 weeks and the control group was instructed to do their usual activity. The hip flexibility was measured with sideward leg splits before and after experiment. The collected data was analyzed using paired t, independent t test.Results:There was a significant increase in the value of sideward leg splits after doing Mat Pilates (p < 0,05), from 98,46±9,73 to 112,82±11,22 for left sideward leg splits and from 99,63±10,20 to 111,39±12,99 for right sideward leg splits. The increase in the value of sideward leg splits in the experiment group was higher than the control group (p < 0,05). It was occured for both left sideward leg splits and right sideward leg splits.Conclusion:Mat Pilates increased hip joint flexibility of young adult with obesity
A 28-Year-Old Male Patient With Right Heart Failure Due To Pulmonary Hypertension Yuri Savitri; Wina Yunida M Siregar; Viola Septina; M Fathul Arif; Arini Nashirah; Narisha Amelia Putri
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 11, No 6 (2022): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v11i6.35882

Abstract

Abstract Right Heart Failure (RHF) as a rapidly progressive syndrome with systemic congestion in the setting of impaired RV filling and/or decreased RV outflow output. A 28-year-old male patient, a photographer, lived in North Aceh was admitted to the ED of Cut Meutia Hospital. He was admitted with worsening dyspnea since 2 days before, initiated after a periode of fever. He also complained of fatigue, palpitations in ordinary activities and chest pain occasionally. He had history of presyncope and syncope. He denied any history of hypertension, type 2 diabetes, allergies, and active smoking. He had no congenital or family history of heart disease. Physical examination revealed full of conciousness with slightly abnormal vital sign. He had malar rash, dilated jugular vein. The apex of the heart shifts to the axilla anterior line, S1>S2 with systolic murmur (+). ECG showed complete RBBB with RAD and chest x-ray showed cardiomegaly. The transthoracic echocardiogram revealed severe TR (Tricuspid Regurgitation), dilatation of RARV (Right Atrium Right Ventricle), with severe PH (Pulmonary Hypertension). The patient was diagnosed with RHF (Right Heart Failure) caused by primary PH. The patient was placed on intravenous furosemide, spironolacton, digoxin, and sildenafil. Treatment and lifestyle modification were expected to improve the quality of life.
Mat Pilates Excercise Increaase Peak Expiratory Flow Rate in Young Adults with Obesity Nugrahani Wiraningrum; Erna Setiawati; Tanti Ajoe Kesoema; Yuswo Supatmo
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 11, No 6 (2022): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jkd (dmj).v11i6.32628

Abstract

Background: Obesity is one of the main problems that keep growing in the world including in Indonesia. Obesity can cause various health problems, one of which is respiratory problems and decreased of pulmonary function parameters in the form of peak expiratory flow rate (PEFR). One of the methods that can be used to increase the pulmonary function parameters of the peak expiratory flow is Mat Pilates exercise. Mat Pilates exercise works by strengthening the core area between the pelvis, abdomen and back, which aims to increase the strength, flexibility and endurance of the respiratory muscles, by that Mat Pilate exercise can increase the peak expiratory flow. However, there have not been any studies that discuss the effect of Mat Pilates exercise on the peak expiratory flow rate in obese young adults.Aim: To prove that Mat Pilates exercise can increasae peak expiratory flow rate of young adults with obesity.Methods: This study used quasi experimental pretest and posttest design and was done in August until October 2020. The subjects were 33 female aged 18-23 years with BMI>27, divided in 2 groups. Experimental group (n=15) was instructed to do 8 weeks of Mat Pilates exercise (3 times a week) and control group (n=18) was instructed to not do any exercise. Peak expiratory flow rate was measured with peak flow meter. Data’s significance was analyzed with Paired T Test and Independent T Test.Results : A significant increase (p<0,001) in peak expiratory flow rate before and after Mat Pilates Exercise. The peak expiratory flow rate at the pretest between the 2 groups was no significant differences (p=0,841). The posttest peak expiratory flow rate of Mat Pilates exercise group (339,44 ± 53,71) was significant (p=0,027) higher than the control group (294,26 ± 56,97). The increase of PERF on Mat Pilates exercise group (45,00 ± 37,27)  is higher significantly (p=<0,001) than the increase on control group (4,07 ± 14,98).Conclusion: Mat Pilates exercise can increase peak expiratory flow rate in young adult with obesity.
A Bibliometric Analysis of Nanocrystalline Cellulose Research as Medical Implant Using VOSviewer Deaniar Hafilah; Asep Bayu Dani Nandiyanto
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 11, No 6 (2022): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v11i6.35896

Abstract

Background: Nanocrystalline cellulose has potential for biomedical applications due to its abundant material availability, biodegradability, biocompatibility, and low weight. Research on nanocrystalline cellulose as medical implants has rarely been studied in the past 10 years, although this material has tremendous potential such as bone implants and cardiovascular implants. Objective: This study aims to analyze the development of research on nanocrystalline cellulose as medical implants using a bibliometric approach with computational analysis using VOSviewer. Methods: The article data was obtained using the Publish or Perish software by retrieving the database from Google Scholar. The keyword “nanocrystalline cellulose, medical implants, biomedical" is used with the publication time span from 2012 to 2020. Data processing uses Microsoft Excel. Computational mapping using VOSviewer. Results: Research on the application of nanocrystalline cellulose has been carried out several times, this can be proven from computational mapping analysis using VOSviewer which shows the term "nanocrystalline cellulose" is in the same cluster as the term "medical implant". However, research on the application of nanocrystalline cellulose as medical implants is still rarely carried out, this is evidenced by the small frequency indicated by the two terms. Conclusion: Based on the results of mapping the collected article data, research on the application of nanocrystalline cellulose as medical implants is an interesting topic. However, this topic is still rarely studied. Therefore, this review can be a starting point for selecting the topic of research on the application of nanocrystalline cellulose materials as medical implants as a consideration for determining the research theme to be taken.

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