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Medula

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Published by Universitas Halu Oleo

ISSN : 23391006 EISSN : 24430218 DOI : http://dx.doi.org/10.33772/medula

Core Subject : Health, Science,

Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Nursing Public Health

MEDULA mengundang kontribusi bagi penelitian original dan fundamental pada bidang kesehatan sebagai sebuah artikel yang melewati proses review.

Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)

Articles 7 Documents

Search results for , issue "Vol 2, No 2 (2015)" : 7 Documents clear

Korelasi Peningkatan Kadar Trigliserida Terhadap Pembentukan Small Dense LDL Pada Pasien Diabetes Melitus Tipe 2 Musyarrafah Musyarrafah; Christiana Lethe; Joko Widodo
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 2, No 2 (2015)
Publisher : Halu Oleo University

Type 2 diabetes increases of triglyceride level due to change of Low Density Lipoprotein (LDL)concentrations, with regard to both numbers and sizes of LDL particles. Small, dense LDL particles are more atherogenic than larger, buoyant LDL and that Apo B is more accurate measure than LDL with regard to predicting cardiovascular disease in patient with type 2 diabetes. This study to determine the correlation between elevated of triglyceride concentration to small dense LDL production in patient with type 2 diabetes. This study was cross sectional design. The subject in this study was type 2 diabetes patient with age more than30 years old (n=33). Triglyceride was analyzed by enzymatic-colorimetric method. Small dense LDL production was calculated by ratio of LDL/Apo B <1.2. Data analysis was performed with Spearman test with significance level of 0.05. The result showed that elevated of triglyceride concentration with small dense LDL formation (ratio of LDL/Apo B <1.2) found on 11 (33.4%) patient, while patient with the elevated of triglyceride concentration and non formation of small dense LDL (ratio of LDL/Apo B≥1,2) found on 9 (23.3%) patient. There was significantly correlation (p=0.027, r= -0.385) between the elevated of triglyceride concentration to the small dense LDL production. In conclusion, the elevated of triglyceride concentration lead to formation of small dense LDL in type 2 diabetes patient. Furthermore, LDL/Apo B ratio could be used as standard parameter to predict cardiovascular disease.Keyword: Type 2 diabetes, triglyceride, Apoliprotein B, small dense LDL.

Uji Efek Antidiabetik Ekstrak Daun Andong (Cordyline fruticosa L. A. Cheval) Mus musculus yang Diinduksi Streptozotosin Parawansah Parawansah; Sifak Giatna; Muhammad Ilyas Yusuf
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 2, No 2 (2015)
Publisher : Halu Oleo University

The plant andong leaf is a medicinal plant that has not been widely used and contains phenolic, flavonoids,tanins and saponins has many benefits, one of which lower blood glucose levels. This study aim to look at the effects of decrease in blood glucose levels in mice that induced by STZs. The method used was experimental research design is RAL with treatment variations leaf extracts 15%, 30% and 45%, glibenclamid as positive control and Na. CMC negative control. The results were analyzed by ANOVA and continued with Duncan. The results showed that there is a very real difference in the treatment given, andong leaf extracts concentrations is themost effective extracts 15% with the average is 17,67 mg/dL on the hour to three.Key words : Leaf andong, antidiabetic, Mus musculus, streptozotocin.

Pengaruh Ekstrak Labu Siam (Sechium edule (Jacq.) Swartz) Terhadap Waktu Koagulasi Pada Mus musculus Nuralifah Nuralifah; Wa Ode Tika Ertia Wahid; Muhammad Ilyas Yusuf
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 2, No 2 (2015)
Publisher : Halu Oleo University

Chayote (Sechium edule (Jacq.) Swartz) is a type of vegetable that contains most of the calcium, the calcium in the blood which stimulates the release of thromboplastin phospholipid that will catalyze changes that have not been activated prothrombin into thrombin active. The purpose of this study was to prove the existance fromthe effect of squash extracts against coagulation time in mice. This study is experimental, which is divided into 5 treatment consisted of 3 repetitions. Extracts of squash as the test material is made a concentration of 100 mg / kg, 200 mg / kg, and 300 mg / kg. Observations made by looking fibrin threads formed on the fracture capillary tube ± for 2-6 minutes after exiting the first blood. The study was conducted in the laboratory of Pharmacology Bina Husada Kendari. Statistical analysis of the results obtained from the ANOVA showed that extracts of squash has an effective effect with 15.33 seconds at a concentration of 300 mg / kg. Results of ANOVA and LSD test showed extracts of squash has an effect on coagulation time significantly.Keywords: coagulation time, extract of squash, Sechium edule (Jacq.) Swartz

Analisis Penggunaan Insektisida Malation dan Temefos Terhadap Vektor Demam Berdarah Dengue Aedes aegypti di Kota Kendari Sulawesi Tenggara Mubarak Mubarak; Tri Baskoro Tunggul Satoto; Sitti Rahmah Umniyati
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 2, No 2 (2015)
Publisher : Halu Oleo University

Malathion and temephos insecticides have long been used at Kendari Municipality in the program of Ae.aegypti mosquito as vector of DHF; however, DHF cases are still relatively high. At Kendari Municipality there is no report on susceptibility status of Ae. aegypti larva and mosquito against malathion and temephos insecticides. This study aimed to identify association between frequency and duration of malation and temephos usage with the susceptibility status of Ae. aegypti larva and mosquito at Kendari Municipality and to identify resistance mechanism of Ae. aegypti larva and mosquito. This study was an observational analytic and subjects of the study were Ae. aegypti larva and mosquito collected from five county in Kendari. Susceptibility status of Ae. aegypti larva and mosquito against malathion and temephos was qualitatively assessed through biochemical test and quantitatively assessed through bioassay test. The statistical analysis perform by using Pearson and One Way Anova. as result, biochemical test of Ae. aegypti larva at counties of Kadia, Rahandouna, Kasilampe and Labibia had tolerant status with average score 2.49; 2.15; 2.05; 2.50 and at Abeli had susceptible status with average score 1.77. Biochemical test of test larva from Kadia, Rahandouna, Kasilampe, Labibia and Abeli showed susceptibility status 0%, 3.33%, 23.33%, 0% and 16.67% subsequently. The result of bioassay test of Ae. aegypti larva against temephos at Kasilampe was resistant (73.3%), at Rahandouna was tolerant (89.3%) and Kadia, Labibia and Abeli were susceptible (100%). The result of bioassay test of susceptibility status of Ae. aegypti mosquito against malathion was 100% for all counties. In conclusion, frequency and duration of use of malathion and temephos through biochemical test not affected significantly against downgrading susceptibility status of Ae. aegypti larva; whereas through bioassay test there was significant effect. Increase of non specific esterase enzyme in Ae. aegypti larva using biochemical test was not because temephos and malathion usage but because there were other unknown factors.Keywords: Aedes aegypti, temephos, malathion, bioassay test, biochemical test, insecticides.

Pengaruh Latihan Progressive Muscle Relaxation Terhadap Status Fungsional Dalam Konteks Asuhan Keperawatan Pasien Kanker dengan Kemoterapi di RS Dr.Wahidin Sudirohusodo Makassar Haryati Haryati; Ratna Sitorus
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 2, No 2 (2015)
Publisher : Halu Oleo University

Chemotherapy is one of the cancer treatment that could provide many side effects and decrease the functional status and quality of life cancer patients. Progressive muscle relaxation (PMR) training is one of the nursing intervention that leads to decreased physical and phsycological effect from chemotherapy. The purpose of this study was to identify the effect of progressive muscle relaxation training on functional status in the context of the nursing care for cancer patients with chemotherapy. This study was a quasi experimental using a nonequivalent control group with pretest and posttest design. The sample was cancer patients who received chemotherapy and inpatient in RS Dr. Wahidin Sudirohusodo Makassar. A concecutive sampling was used as the sample collection method and 48 subjects were obtained this study, divided into two groups, each group consisted of twenty four subjects as intervention group who were given PMR training twice a day for seven days, and twenty four subjects as control group who were not given PMR training. The instrument that used in this study were demography form and Functional Living Index-Cancer to measure functional status which consisted 22 questions with 7-point Likert-Type linear analog scale. A T test was used to examine the differences of the mean of functional status scores and each dimension. The finding showed that there was a significant increased of the mean of functional status after PMR training in intervention group (p=0,000). It means that PMR training has an effect in increasing level of functional status in cancer patients with chemotherapy. It is recommended to apply PMR training as a nursing intervention to cancer patients with chemotherapy and suggested to conduct futher research using more samples.Key Word: cancer, chemotherapy, functional status, progressive muscle relaxation

Korelasi Antara Pola Makan, Cara Menggosok Gigi, Pengetahuan dan Sikap dengan Status Karies Gigi Pada Siswa Sekolah Menengah Pertama Riszki Riszki; Sulastrianah Sulastrianah
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 2, No 2 (2015)
Publisher : Halu Oleo University

Dental Caries is one of the most common mouth disease in children. According to the data obtained from Public Health Centre in North Buton regency, since 2011 to 2013 there were 304, 141 and 167 cases of dental caries respectively in Kulisusu District, placing the dental caries at the eigth rank. The aim of this study is to determine the correlation between dietary habit, way of teeth brushing, knowledge and attitude in dental health with dental caries status at SMPN 4 Kulisusu in North Buton regency in 2014. The design of this study is analytic observational with cross sectional approach. The population was consist of 98 students and the samples were obtained by total sampling method. A questionnaire was distributed to measure dietary habit, way of teeth brushing, knowledge and attitude. The Dental caries status was obtained using DMF-T Index.The data analyzed by conducting Somer’s test at the significance level 0,05. The result of this study showed that 60,2% respondent have poor dietary habit, 68,4% respondent not brushing their teeth with good manner, 39,8% respondent do not have good knowledge about dental health and 51,0% respondent do not have good attitude in dental care.According to DMF-T index, 10,2% have very high index, 25,5% have high index, 37,8%, have moderate index, 18,4% have low index and 8,1% have very low index. The conclusions of the study showed that there were statistically significant relationships between dietary habit, way of teeth brushing and attitude with dental caries status (p = 0,001, 0,000, and 0,031 respectively). Knowledge has no statistically significant relationship with dental caries status (p-Value = 0,867).Keywords: dental caries status, dietary habit, way of teeth brushing, knowledge, attitude, Junior high School

Perbandingan Metode Proporsi dengan Metode Resazurin Microtiter Assay (Rema) untuk Deteksi Mycobacterium tuberculosis yang Resisten Terhadap Rifampisin Yenti Purnamasari; Sartini Sartini; Faisal Attamimi; Muh. Nasrum Massi
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 2, No 2 (2015)
Publisher : Halu Oleo University

Tuberculosis (TB) is one of the high infectious diseases in Indonesia caused by Mycobacteriumtuberculosis. Drugs which used for tuberculosis therapy has been widely reported experiencing resistance, while inappropriately treatment will lead to not effective and efficient care. Culture in Lowenstein Jensen medium is a gold standard to perform the drug susceptibility but it takes a long time to get results, therefore, new methods were developed to replace it, one of them is colorimetric method. This research aimed to compare Rifampicin susceptibility test in colorimetric method use REMA and culture method use Lowenstein Jensen medium. This study was a cross sectional with experimental laboratory design used 42 sputums from patients with tuberculosis, done at October 2010 until March 2011. In this research, 5 samples rifampicin resistant have been detected. As a results, we founded Rifampicin susceptibility test of REMA have 80 % sensitivity, 100 % specificity, 100 % PPV, and 97 % NPV when compared with culture method.Keywords:Proportion, Resazurin, Mycobacterium tuberculosis, Resistance

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Home Page

OAI Link

Editorial Team

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Contact Name Sulastrianah

Contact Email sulastrianahmuhtadi@gmail.com

Phone +6285242541601

Journal Mail Official sulastrianahmuhtadi@gmail.com

Editorial Address Kampus Hijau Bumi Tridharma Anduonohu Kendari Universitas Halu Oleo Fakultas Kedokteran

Location Kota kendari, Sulawesi tenggara INDONESIA

Abstract

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Contact Name
Sulastrianah

Contact Email
sulastrianahmuhtadi@gmail.com

Phone
+6285242541601

Journal Mail Official
sulastrianahmuhtadi@gmail.com

Editorial Address
Kampus Hijau Bumi Tridharma Anduonohu Kendari Universitas Halu Oleo Fakultas Kedokteran

Location
Kota kendari,

Sulawesi tenggara

INDONESIA