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All Journal Rekayasa: Jurnal Penerapan Teknologi dan Pembelajaran Indonesian Journal of Cancer Chemoprevention Indonesian Journal of Biotechnology Indonesian Journal of Chemical Science Jurnal Eurekamatika Pattimura Proceeding : Conference of Science and Technology
Amalina, Nur Dina
Pharmacy Study Program, Faculty Of Mathematics And Natural Sciences, Semarang State University, Semarang
Agriculture, Biological Sciences & Forestry Astronomy Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Energy Engineering Immunology & microbiology Industrial & Manufacturing Engineering Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Physics

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Cytotoxic Activity of Hyptis Pectinate Extracts on MCF-7 Human Breast Cancer Cells Nur Dina Amalina; Meiny Suzery; Bambang Cahyono
Indonesian Journal of Cancer Chemoprevention Vol 11, No 1 (2020)
Publisher : Indonesian Society for Cancer Chemoprevention

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14499/indonesianjcanchemoprev11iss1pp1-6

Abstract

Hyptis pectinata (L.) poit, popularly known in the world as “comb bushmint” is a medicinal plant commonly used for the treatment of throat and skin inflammations, bacterial infection, pain and cancer. The objective of this research is to determine the cytotoxic and antiproliferative effect under Hyptis pectinata ethanolic extract (HPE) treatment on breast cancer cells. The effect HPE of on cytotoxicity was examined by MTT assay on MCF-7 breast cancer cells. This assay also used to determine cell proliferation over 3 days of treatment with 1.5 – 100 µg/mL HPE. HPE showed that exhibited cytotoxic effects with IC50 value of 30 µg/mL for 24 hours and changes the physiological morphology on MCF-7 cells. Interestingly, the treatment of HPE for 48 and 72 hours highly decreases cell viability on MCF-7 with dose and time-dependent manner compared to untreated cells. These results indicate that HPE has antiproliferative activities and maybe the potential to be developed as a natural chemotherapeutic agent.Keywords: Hyptis pectinata (L.) poit extract, cytotoxicity, antiproliferative, MCF-7 cells
BUKTI ALTERNATIF INTERPOLASI KOMPLEKS RUANG LEBESGUE DENGAN EKSPONEN PEUBAH Dina Nur Amalina; Denny Ivanal Hakim
Pattimura Proceeding 2021: Prosiding KNM XX
Publisher : Pattimura University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1044.705 KB) | DOI: 10.30598/PattimuraSci.2021.KNMXX.61-66

Abstract

Co-Authors Agung Putra Bambang Cahyono Bayu Tirta Dirja Damar Nurwahyu Bima Denny Ivanal Hakim Edy Meiyanto Encum Sumiaty, Encum Endang Susilaningsih Harjito - Ika Putri Nurhayati Kurniasari, Laviona Tiara Masta, Al Azhary Meiny Suzery Murbangun Nuswowati Nanik Wijayati Pangesti Drawina Sri Kadarwati Taufiqurrachman Nasihun Yan Wisnu Prajoko