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Analgesic Activity of Ethanol Extract of Temu Giring Rhizome (Curcuma heyneana Val & Zijp) in Mice Marianne; Khairunnisa; Wilda
Indonesian Journal of Pharmaceutical and Clinical Research Vol. 1 No. 2 (2018): Indonesian Journal of Pharmaceutical and Clinical Research
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (800.784 KB) | DOI: 10.32734/idjpcr.v1i2.535

Abstract

Temu giring (Curcuma heyneana Val & Zijp) is a traditional medicinal plant that is believed in community as an analgesic. The objective of this research was to determine the analgesic activity of the C. heyneana rhizome by using infra red (IR) thermal induction method in mice. Mice were divided into 7 groups. Group 1 served as negative control, group 2,3,4,5 served as treatment groups which is given ethanolic extract of C. heyneana rhizome at dose of 5, 25, 125, and 625 mg/kg respectively, group 6 and 7 served as comparable groups, given antalgin 65 mg/kg and morphine sulphate 1.3 mg/kg respectively. The observation have been done, included to pain resistance of mice which exposed by infra red (IR) every 10 minutes for 80 minutes. The data were analyzed by ANOVA at the significance level of 95%. Ethanolic extract of C. heyneana at the doses of 25, 125, and 625 mg/kg had significant effect to reduce the pain compared to the negative control (p<0.05). Ethanolic extract of C. heyneana rhizome at dose of 125 mg/kg, had the same effect to antalgin 65 mg/kg (p≥0.05), while the ethanolic extract of C. heyneana at the dose of 625 mg/kg had the same effect as morphine sulfate 1.3 mg/kg (p≥0.05). It can be concluded that ethanolic extract of C. heyneana rhizome has analgesic activity. Keywords: temu giring, analgesic, Curcuma heyneana, rhizome
PEMBINAAN MASYARAKAT SEBAGAI APLIKASI GERAKAN MASYARAKAT CERDAS MENGGUNAKAN OBAT (GeMa CerMat) Khairunnisa; Embun Suci Nasution
ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat Vol. 2 No. 2 (2017): ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1140.13 KB) | DOI: 10.32734/abdimastalenta.v2i2.2304

Abstract

Masalah penggunaan obat tidak rasional merupakan masalah yang menjadi perhatian besaroleh Kementerian Kesehatan Indonesia. Pada masyarakat seringkali dijumpai berbagai masalahdalam penggunaan obat, misalnya penggunaan obat bebas secara tidak tepat dan kurangnyapemahaman tentang cara menggunakan, cara menyimpan dan membuang obat-obatan secara tidaktepat. Hal ini disebabkan masih kurangnya pemahaman masyarakat dan perilaku yang salah dalampenggunaan obat. Oleh karena itu, untuk meningkatkan pemahaman masyrakat dalam penggunaanobat perlu dilakukan edukasi kepada masyarakat mengenai pemilihan obat dan penggunaan obatyang rasional melalui pelatihan yang merupakan bagian dari Gerakan Masyarakat CerdasMenggunakan Obat (GeMaCerMat).Pelatihan GeMaCerMat ini menggunakan metode Cara Belajar Ibu Aktif (CBIA). Metode inisesuai digunakan untuk melakukan edukasi tentang penggunaan obat rasional terutama dalampenggunaan obat swamedikasi dan metode ini kami tawarkan dalam kegiatan pengabdian ini.Hal inikarena sasaran dari pengabdian ini merupakan ibu rumah tangga yang mempunyai peranan pentinguntuk mengambil keputusan dalam penggunaan obat di keluarga. Metode CBIA ini dibagi dalam 3tahapan: kegiatan I dan II dilakukan dalam kelompok, dan kegiatan III dilakukan secara individualdi rumah dan dievaluasi dalam pertemuan berikutnya.Hasil dari kegiatan pengabdian masyarakat ini sangat membantu dan dapat memberikanmanfaat yang baik kepada masyarakat karena kegiatan ini dapat memberikan dampak yang cukupbesar terhadap kesehatan masyarakat. Kegiatan pengabdian ini terbukti mampu meningkatkanpersepsi dan pemahaman masyarakat terhadap penggunaan obat-obatan secara rasional terutamaobat-obatan yang diguna sebagai pengobatan swamedikasi. Metode kegiatan CBIA sebagai metodepembelajaran kepada masyarakat banyak digunakan dan sangat efektif sebagai metode edukasikesehatan kepada masyarakat.
Study on Acute Oral Toxicity of Ethanolic Extract of Annonasquamosa Leaves in Mice (Musmusculus) Khairunnisa; Dita Utami, Andini; Marianne
Indonesian Journal of Pharmaceutical and Clinical Research Vol. 1 No. 1 (2018): Indonesian Journal of Pharmaceutical and Clinical Research
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1025.288 KB) | DOI: 10.32734/idjpcr.v1i1.205

Abstract

Abstract. The aims of this study were to determine the potential for acute oral toxicity of ethanolic extract of A.squamosa leaves with LD50 and the histopathological changes in liver and kidney of mice.This research used experimental method as per fixed dose method. The number of animals used in this research were 20 female mice. The study was divided into 2 steps, there were sighting and main studies. The control group was given Na-CMC 0.5%, the treatment groups were given ethanolic extract of A.squamosa leaves with doses of 5, 50, 300, 2,000 and 5,000 mg/kg bw. The results showed that the ethanolic extract of A.squamosa leaves with doses of 2,000 and 5,000 mg/kg bw did not show any toxicity signs. At a dose of 5,000 mg/kg bw caused hydropic degeneration, necrosis hepatocyte, glomerular atrophy, and tubular dilatation. There was no mortality was observed.It was estimated that LD50 of ethanolic extract of A.squamosa leaves was higher than 5,000 mg/kg bw and the extract were practically non-toxic. Keywords: Acute Toxicity, Annona squamosa, Ethanolic Extract
TINDAK BAHASA GURU DALAM PEMBELAJARAN BAHASA INDONESIA DI KELAS VIII SMPN 7 BANJARMASIN Khairunnisa; Fatah Yasin, Moh.; Noortyani, Rusma
LOCANA Vol 2 No 2 (2019): LOCANA: JURNAL TUGAS AKHIR MAHASISWA
Publisher : Program Studi Pendidikan Bahasa dan Sastra Indonesia, Fakultas Keguruan dan Ilmu Pendidikan, Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jtam.v2i2.28

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PENERAPAN METODE FRAME BY FRAME DALAM PEMBUATAN ANIMASI TATA CARA HAJI SESUAI SUNNAH RASUL MENGGUNAKAN APLIKASI 3DS MAX Aldina Syahfaridzah; Khairunnisa; Dharmawati
METHOMIKA: Jurnal Manajemen Informatika & Komputerisasi Akuntansi Vol. 5 No. 1 (2021): METHOMIKA: Jurnal Manajemen Informatika & Komputersisasi Akuntansi
Publisher : Universitas Methodist Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46880/jmika.Vol5No1.pp9-16

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Advances in technology in the field of information are developing very rapidly at this time, especially information in the field of animation. The animation is a visual form that moves and is used to present information and learning that is difficult to understand if delivered in general. The use of animation media is specially made to find out the procedures for the Hajj pilgrimage in order to increase knowledge for someone who wants to perform the Hajj or want to know the Hajj procedures because Hajj is the fifth pillar of Islam where if someone carries it out, much wisdom will be gained. Information about the pilgrimage procedures is packaged with 3D animation and created using 3Ds Max application and the frame by frame method, where all movements of the animation are arranged using frames. So that the resulting learning media, namely animated videos that add insight and information for someone because it is packaged with media that is more attractive and easy to understand, namely animation.
Perlindungan Anak Pasca Perceraian Orang Tua Iksan; Adnan; Khairunnisa
Fundamental: Jurnal Ilmiah Hukum Vol. 9 No. 1 (2020): Fundamental: Jurnal Ilmiah Hukum
Publisher : Sekolah Tinggi Ilmu Hukum Muhammadiyah Bima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34304/fundamental.v1i1.9

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Perkawinan sebagai sesuatu yang sacral bagi umat islam terkadang akan berakhir dengan perceraian karena disebabkan oleh berbagai hal. Perceraian ini pun dikemudian hari juga terkadang akan memunculkan masalah terutama siapa dan bagaimana tanggung jawab orang tua yang telah bercerai berkaitan dengan pemeliharaan anak. Dalam berbagai kasus ketika pasangan suami istri bercerai maka hak-hak anak terkadang diabaikan oleh kedua belah pihak baik dilakukan secara sengaja maupun tidak. Oleh karena itu, perlu upaya perlindungan agar hak-hak anak dapat terpenuhi. Berdasarkan latar belakang tersebut peneliti mencoa mengangkat judul penelitian perlindungan anak pasca perceraian orang tua. Metode yang digunakan adalah yuridis-normatif. Dengan alat pengumpul datanya adalah dokumentasi/mengkaji dari aspek kepustakaan. Hasil penelitian menunjukan bahwa sesungguhnya peraturan yang dibuat oleh Negara sudah cukup memberikan perlindungan kepada anak pasca perceraian orang tua. Ketentuan mengenai siapa yang punya tanggung jawab utama dalam memnberikan nafkah kepada anak setelah bercerai, tentu bapaknya. Apabila bapak sudah tidak menyanggupinya baru diserahkan kepada Ibunya. Apabila ketentuan tersebut di langgar maka ada ketentuan pidana yang mengatur khususnya pasal 76A dan 76B. Hal ini sebagaimana termuat dalam Undang-Undang Nomor 23 Tahun 2002 kemudian di revisi dengan Undang-Undang Nomor 35 Tahun 2014 tentang Perlindungan anak.
Validity And Reliability of he English Summative Test For Second Semester of he Fifth Grade in Academic Year 2019/2020 Khairunnisa; AnniHolila Pulungan; Rahmad Husein
International Journal of Educational Research & Social Sciences Vol. 2 No. 1 (2021): February 2021
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijersc.v2i1.21

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The validity and reliability of the test is very important before the test is used to measure student achievement. This study aims to analyze the validity and reliability of the summative English test for fifth grade public elementary schools 058238 Bukit Rata in the academic year 2019/2020, and to investigate the quality level of the summative test of English in elementary schools. This research is a quantitative descriptive study. The subjects in this study were students of grade V public elementary school 058238 Bukit Rata in the academic year 2019/2020. The data analysis technique used is quantitative analysis by testing the validity, reliability, level of difficulty, distinguishing power, and tricking effectiveness. The data obtained were analyzed using the ANATES version 4 program and manual calculations using Microsoft Excel. The results showed that, the level of validity of the English test in grade 5 elementary school before the revision based on material aspects, construct aspects and language aspects obtained a percentage of 73% with a good category. After being revised, based on material aspects, construct aspects and language aspects obtained a percentage of 90% with a good category. The reliability test was carried out twice, namely the questions before expert validation and after expert validation. The results of the reliability test on the first question were the value of -0.084 in the unreliable category because the value was ≤ 0.700. Furthermore, the second test of English test reliability was carried out. The results of the second test reliability test, namely the KR 20 formula with the help of the Excel program obtained a value of 0.413 in the sufficient category. The level of validity and reliability of the English test in grade 5 elementary schools. Before the revision, the number of valid questions was 4 valid questions or 16% of the total questions. Furthermore, the number of questions that can be accepted is 17 questions, but 13 questions are not valid. So it is necessary to improve the overall problem. After the revision was made, the number of valid questions was 16 valid questions or 64% of the total questions. Furthermore, the number of questions that can be used is 15 questions, because one significant question has a low difference power, so the question is not used. The validity and reliability of the English test in fifth grade public elementary school 058238 Bukit Rata should be revised becausereliability is used as an indicator in believing the value of a test because it has consistency. While the test must be valid because it is used as a development and evaluation of a test. In addition, validity is also needed to determine the feasibility of items.
ANALISIS HAMBATAN PEMBELAJARAN JARAK JAUH OLEH GURU PADA MASA PANDEMI COVID-19 DI SDN 41 AMPENAN Dwi Septina, Lensi; Khairunnisa; Siti Istiningsih
JURNAL ILMIAH PENDAS: PRIMARY EDUCATION JOURNAL Vol 1 No 2 (2020): Desember 2020
Publisher : Program Studi PGSD, FKIP, Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/pendas.v1i2.63

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Penelitian ini bertujuan untuk mengetahui pelaksanaan pembelajaran jarak jauh dan hambatan yang dihadapi dalam pelaksanaan pembelajaran jarak jauh serta strategi yang digunakan oleh guru dalam melaksanakan pembelajaran jarak jauh. Penelitian ini menggunakan pendekatan kualitatif deskriptif. Populasi dalam penelitian ini adalah guru SDN 41 Ampenan dengan jumlah 9 guru. Teknik pengumpulan data dalam penelitian ini menggunakan observasi dan wawancara. Teknik analisis data yang digunakan adalah Interactive Analysis Model. Hasil penelitian menunjukan terdapat dua hambatan dalam pelaksaan pembelajaran jarak jauh yaitu kurangnya dukungan serta pengetahuan orangtua dalam pelaksanaan jarak jauh dan kurangnya kemampuan guru melaksanakan pembelajaran jarak jauh secara daring.
Psychopathology in Entrepreneurship in Medan, North Sumatra Elvinawanty, Rianda; Chaiyadi, Soemarco; Amelia, Firda; Khairunnisa
Journal of Research in Business, Economics, and Education Vol. 2 No. 6 (2020): December Edition
Publisher : Kusuma Negara Business School

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Entrepreneurs in conducting their business can experience failures that can occur at any time. As a result of the failure of entrepreneurship is very diverse, such as stress, depression, and experiencing mental stress. This research aimed to explain the psychopathological picture of failed entrepreneurs. This research used qualitative research methods and the sampling technique used is purposive sampling technique. Data obtained through interview and observation methods. The reason researchers used this research technique was to find more about psychopathological aspects of failed entrepreneurs. The results showed that entrepreneurship psychopathology has a significant role in determining success and failure in entrepreneurship. Of all the subjects, the sense of distrust is the aspect that has the most significant role.
Evaluation of Supplement Consumption on North Sumatera Regional Police Headquarters Personnel Munazar; Wiryanto; Khairunnisa
Indonesian Journal of Pharmaceutical and Clinical Research Vol. 3 No. 2 (2020): Indonesian Journal of Pharmaceutical and Clinical Research
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/idjpcr.v3i2.4333

Abstract

The purpose of his study was to determine the factors that influence the consumption pattern of supplements, and to prove the potential interactions of anti-cholesterol, antihypertensive, anti-uric acid, and antidiabetic drugs with supplements. This research is a descriptive research with a survey method. Data collection was carried out on 373 North Sumatera Regional Police Headquarters Personnel. This study used the dependent variable, namely the pattern of supplement consumption, while the independent variables were age, gender, health status, perception, information sources and physical activity. The results of the study using descriptive statistical tests presented using tables and percentages. The results showed that the factors that influenced the pattern of supplement consumption were male (57.1%); 30-49 years old (62.5%); healthy condition (63%); perception as a stamina enhancer (61.7%); sources of information (62.2%) and strenuous physical activity (49.9%). There are synergistic interactions of anti-cholesterol drugs with supplements and antagonistic interactions of antihypertensive, anti-diabetic, anti-gout drugs with supplements.