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Journal : Indonesian Journal of Pharmaceutical Education

Pengaruh Puasa Ramadhan Terhadap Tekanan Darah Dan Profil Lipid Pada Pasien Hipertensi Studi Kasus : Denpasar Selatan I Wayan Happy Candra Dinata; Dhiancinantyan Windydaca Brata Putri; Gusti Ngurah Agung Windra Wartana Putra; I Gusti Ngurah Mayun
Indonesian Journal of Pharmaceutical Education Vol 3, No 3 (2023): September-Desember 2023
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v3i3.21914

Abstract

Hypertension is the most common cardiovascular disease in society. Management of hypertension can be pharmacological and non-pharmacological. One of the nonpharmacological therapies for hypertension is fasting therapy. Ramadan fasting is fasting that is obligatory for Muslims and has been set in the month of Ramadan for one month (29 or 30 days). Fasting changes a person's eating and drinking patterns which affect the body's metabolism which results in increased production of angiotensinogen which impacts blood pressure and increases in High-density Lipoprotein cholesterol. The purpose of this study was to determine the effect of Ramadan fasting on blood pressure and lipid profiles in hypertensive patients. This study used a pre-experimental research design with the One Group Pretest-Posttest model. The sampling method used non-probability sampling with purposive sampling technique. Measurements were taken before the fasting month of Ramadan and one month of fasting. Data analysis using the Wilcoxon test. The results of the study in the form of systolic and diastolic blood pressure before fasting with one month of Ramadan fasting, the mean ± SD respectively were 145 ± 17.45 p-value (0.001); 87.70 ± 9.82 p-value (0.001). For lipid profiles (cholesterol, triglycerides, HDL, LDL) before fasting with one month of Ramadan fasting, the mean ± SD respectively were 181.60 ± 26.63 p-value (0.001); 113.65 ± 43.91 p-value (0.001); 53 ± 7.71) p-value (0.001); 116.30 ± 18.38 p-value (0.001). This study concluded that there was a decrease in systolic and diastolic blood pressure, and an improvement in fasting lipid profile levels during Ramadan fasting in hypertensive patients.
Perbaikan Profil Lipid pada Masyarakat Muslim Hiperlipidemia dengan Puasa Ramadhan di Denpasar Selatan Ni Putu Juli Martasari; Dhiancinantyan Windydaca Brata Putri; I Gusti Lanang Made Rudiartha; Putu Yudhistira Budhi Setiawan
Indonesian Journal of Pharmaceutical Education Vol 3, No 3 (2023): September-Desember 2023
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v3i3.21913

Abstract

Ramadan fasting is an activity to refrain from eating and drinking, which is very beneficial for health, one of which is in improving lipid profile levels that are disturbed or commonly called hyperlipidemia because fasting can reduce saturated fatty acid intake, increase fiber intake, reduce carbohydrate and alcohol intake. Hyperlipidemia is a lipid metabolism disorder characterized by an increase or decrease in lipid fraction levels in plasma such as an increase in total cholesterol, LDL, and triglyceride levels and a decrease in HDL levels. This study aims to determine the effect of Ramadan fasting on the lipid profile of hyperlipidemia patients in the Kepaon Islamic village community. This research is a quantitative study, with a pre-experimental research design using the One Group Pretest-Posttest model with purposive sampling taking. The examination includes total cholesterol, LDL, HDL, and triglycerides before and one month after fasting. The results of this study showed significant changes in the form of decreases in total cholesterol, triglycerides, and LDL levels with average values as follows 221.60±40.59 to 189.85±19.27; 149.65±66.07 to 103.10±43.96; and 153.20±34.23 to 116.60±18.91 with a p-value significance of 0.001. And there was an increase in HDL levels with an average value of 38.55±8.89 to 57.10±13.55 with a p-value significance of 0.001. This study can be concluded that Ramadan fasting decreases total cholesterol, triglycerides, and LDL levels and increases HDL levels.