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All Journal Justek : Jurnal Sains Dan Teknologi Journal of Public Administration Studies JURNAL FARMASIMED (JFM) Al Ashriyyah Jurnal Manajemen dan Budaya Talimi

Parhan, Parhan

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Author-ID : 1877693

Religion Arts Humanities Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Education Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Mathematics Medicine & Pharmacology Social Sciences Other

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Penetapan Kadar Na-Siklamat Pada Minuman Serbuk Instan Dan Minuman Kemasan Kaleng Yang Diperdagangkan Di Delitua Dengan Metode Alkalimetri Parhan, Parhan
Jurnal FARMASIMED (JFM) Vol 1 No 1 (2018): Jurnal FARMASIMED (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Packaging beverages or soft drinks are non-alcoholic beverages, processed or powdered liquors containing foodstuffs or other additives both natural and synthetic packaged in ready-to-eat packaging. Instant powder drink is one of the fast food beverage products that contain many artificial sweeteners. The most commonly used artificial sweetener is Na-cyclamate. The use of Na-Cyclamate in large doses will cause health problems. The purpose of this research is to know and compare the content of Na-Cyclamate in instant powder drink with beverage of canned packaging traded in Delitua with provisions SNI 01-6993-2004 that is 1000 mg / kg BB. Samples were collected from drink merchants in Delitua who sold instant powder beverages according to qualitative qualitative analysis criteria that aimed to see the Na-Cyclamate content in the sample by using the sedimentation test with BaCl2. Positive samples containing Na-Cyclamate were determined by Alkalimetry. The results showed that 6 samples of instant powdered beverage and canned container beverage contained Na-Cyclamate with content: A (402,2629 mg / kg), B (395.9280 mg / kg), C (405,4303 mg / kg ), D (272.3985 mg / kg), E (269.2311 mg / kg), and F (392.7606 mg / kg). From the data obtained, it is known that the samples A, B, C, D, E and F are safe for consumption, since the Na-Cyclamate content of the sample does not exceed the limits set by SNI 01-6993-2004 based on the food category of 1000 mg / kg. Na-Cyclamate content found in instant powder drink is higher than Na-Cyclamate levels contained in beverage cans packaging.

Pengaruh Kecepatan Pembentukan Tukak Lambung Terhadap Pemberian Berbagai Golongan NSAID Pada Tikus Jantan Parhan, Parhan; Gulo, Aliman Yafarugi
Jurnal FARMASIMED (JFM) Vol 1 No 2 (2019): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Background : Gastric ulcer is wound to the mucosal layer (epithelial layer) of the stomach and mucosal irritation of 5 mm or more in diameter with depth down to submucosa. The basic pathogenesis of gastric ulcers in when there is an imbalance of aggressive factor enhancement. Non-steroidal antiinflammantory drug can cause stomach ulcers in two ways, either directly or topical irritation of the epithelial tissue and inhibit the endogeneous system of gastrointestinal mucosa of prostaglandins. In this case inhibition of prostaglandin systhesis is the dominant factor of peptic ulcers by NSAIDs. Objectives : The purpose of this study was to determine the effct of NSAID drug administration on the formation of peptic ulcers and to know the difference in the rate of formation of peptic ulcers from each class. Method : Sampel method mice performed surgery on the stomach is done in Pharmacology Laboratory of Pharmacy Institute Deli Husada Deli Tua. Results : The results of this study indicate that faster drugs cause gastric ulcers with a degree of redness are Aspirin 4.03 mm, 2.01 mm mefenamat and 1.02 mm Diclofenac Sodium while Ibuprofen mwdication does not cause peptic ulcers. Conclusion : The results of this study it can be concluded that Aspirin administration with doses of 21 mg/kg faster causes gastric ulcers from other NSAID groups such as Mefenamat with a dose of 21 mg/kg BW, Diclofenac sodium at a dose of 2 mg/kg while administration, Ibuprofen for ten days does not couse ulcers in the stomach of experimetal animals.

Co-Authors Abdul Jalil, Muhammad Abdul Rozaq AFIYAH, NUR Fidyarini, Lailly Gulo, Aliman Yafarugi Haeruddin Haeruddin Idrus Idrus Ikhwan, Subaiki Isyanto, Nur Jalil, Muhammad Abdul` Mahsup, Mahsup Maksum, Ghufron Mohamad Syafi’i Mudiono, Mudiono Muhibbin, Muhibbin Mursalim Mursalim Pala, Nurul Safii, Mohamad Sidik, Alan Muhamad Taofik Maulana Sitinurmala, Sitinurmala Sitisaini, Sitisaini Supiani Supiani, Supiani Taufikhidayat, Taufikhidayat Zainuddin, Zainuddin Zairina, Nuren

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