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All Journal JURNAL GIZI INDONESIA Jurnal Kedokteran Brawijaya Jurnal Ilmiah Kedokteran Wijaya Kusuma Health Notions Makara Journal of Health Research
Merryana Adriani
Fakultas Kesehatan Masyarakat Universitas Airlangga, Indonesia
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Medicine & Pharmacology Nursing Public Health

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Journal : JURNAL GIZI INDONESIA

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Hubungan serum seng dengan jumlah CD4 pada lansia di Panti Jompo Sugeng, Maria Widijanti; Adriani, Merryana; Wirjatmadi, Bambang
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 2, No 1 (2013)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (398.212 KB) | DOI: 10.14710/jgi.2.1.

Abstract

Background: Elderly people tend to have higher susceptibility to infections because of immune dysfunction, especially cell-mediated immune system which is related to zinc deficiency. Zinc has an important role in the cell-mediated immune system which can be determined by CD4 count. Objectives: To determine the zinc level in the serum and CD4 count in healthy elderly and the correlation between the zinc level in the serum and CD4 count. Method: This was a randomized cross-sectional study. Twenty seven healthy elderly subjects of both sexes aged 60-90 years were recruited for this study from a senior center. Zinc level in the serum and CD4 count were measured. Result: The average of CD4 count was 710 + 269 cells/ml, and the average of zinc level in the serum was 87,29 + 10,27 μg/dL. Twenty six percent elderly had low CD4 count (<460cells/ml. There was no zinc deficiency among the elderly but 30% elderly had zinc level 70- 80 μg/dL. There was a significant correlation (p<0,05) between zinc level and CD4 count, which was analyzed using Pearson correlation method.Conclusion: CD4 count has correlation with zinc level in the serum in elderlyKeywords: Zinc level, CD4 count, elderly
Kadar radikal superoksid (O2-), nitric oxide (NO) dan asupan lemak pada pasien hipertensi dan tidak hipertensi Astutik, Pudji; Adriani, Merryana; Wirjatmadi, Bambang
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 3, No 1 (2014)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (452.1 KB) | DOI: 10.14710/jgi.3.1.90-95

Abstract

Background: Hypertension closely related to impaired endothelial dependent vasodilation due to a decline in theavailability of nitric oksid (NO) and high fat intake, decreased Nitric Oksid caused due to increased levels ofsuperoksid.Objective: to analyze the differences in the levels of Superoksid Radical (O2-), Nitric oxide (N0) and fat intake inpatients with hypertension and not hypertension .Methods: this research is cross sectional, research amount sampelnya taken at random. 24 respondent patientsconsisting of 12 cases control, and 12 the age of 65 40- tahun.pengambilan samples conducted in outpatient installationregional general hospital Sidoarjo. Done bseline superoksid levels, nitric oxide and recall fat intake.Results: the average rate of Superoksid respondents not hypertension 0.250± 0, 034U/mL, 0,314± 056U/mLhypertension, Average levels of Nitric oksid respondents not hypertension 116,083± 46,962μ M, of which hypertension72,333± 40,51μ M, average consumption of fat respondents not hypertension 41,65± 8, 32gram, 51,52± 6,74gramhypertension . Based on the test results the difference against Superoksid levels of both research groups using a t-testtwo samples are free retrieved the value p < 0,05 (p = 0,004), NO content retrieved the value p < 0,05 (p = 0,023), fatintake obtained the value of p < 0,05 (p = 0,004) which means that there is a meaningful difference in the levels ofSuperoksid, Nitric oxide and the level of fat intake among respondents with no hypertension and hypertension.Conclusion: there is a radical difference in the levels of Superoksid, NO (Nitric Oxide) and fat intake in patients withhypertension and not hypertension.
Co-Authors Ade Saputra Nasution Arwati, Niluh Astuti, Nanik Dwi Aulia, Kharina Bambang Purwanto Bambang Wirjatmadi Desy Prasetya, Desy Dwi Putra, Kartika Wahyu Dwi Winarni Fara Disa Durry, Fara Disa Fatifa Asmarani, Fatifa Jujuk Proboningsih, Jujuk Kuntoro Kuntoro M., Soenarnatalina Maria Widijanti Sugeng Meirna Dewita Sari, Meirna Dewita Novera Herdiani, Novera Nur Nashriana Jufri Oktovina Rizky, Oktovina Priaminda, M Dodi F Pudji Astutik, Pudji R. Bambang Wirjatmadi, R. Bambang Raharja, Kristian Triatmaja Rahayu, Aprilia Nurcahyaning Rahmi Syarifatun Abidah, Rahmi Syarifatun Setiarsih, Dini Sholikhah, Anindya Maratus` Sholikhah, Desty Muzarofatus Soenarnatalina Meilanani, Soenarnatalina Sri Hartiningsih Susanti, Yuyun Erlina Wijatmadi, Bambang