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All Journal Jurnal Teknik Sipil Al-Ulum Al-Mizan (e-Journal) Jurnal Ilmu Kelautan Spermonde Paediatrica Indonesiana JURNAL KESEHATAN LINGKUNGAN: Jurnal dan Aplikasi Teknik Kesehatan Lingkungan Indonesian Journal of Artificial Intelligence and Data Mining Jurnal Ilmiah AL-Jauhari Jurnal Studi Islam dan Interdisipliner TAHKIM JURNAL ILMIAH M-PROGRESS Budapest International Research and Critics Institute-Journal (BIRCI-Journal): Humanities and Social Sciences Jurnal Dinamika Informatika (JDI) Darussalam : Jurnal Ilmiah Islam dan Sosial TARBIYAH DARUSSALAM: JURNAL ILMIAH KEPENDIDIKAN DAN KEAGAMAAN Surya Pasca Scientia
Ahmad Faisal
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Journal : Paediatrica Indonesiana

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Comparison of absolute neutrophil count between premature and term infants Ahmad Faisal; Guslihan D Tjipta; Bidasari Lubis; Dachrul Aldy
Paediatrica Indonesiana Vol 44 No 5 (2004): September 2004
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (317.906 KB) | DOI: 10.14238/pi44.5.2004.197-200

Abstract

Background Neutrophils are very important in the body defenseagainst bacterial infection. Absolute neutrophil count (ANC) couldbe used for the recognition of early-onset bacterial sepsis inneonates.Objective The aim of this study was to compare the value of ANCbetween premature and term infants, to assess the prevalence ofearly-onset neutropenia in premature infants and its relationshipwith prematurity, and to find out the correlation between gesta-tional age and ANC.Methods A cross-sectional study was conducted during Februaryto May 2003. Subjects were newborn infants with gestational ageof less than 37 weeks who were born in Adam Malik and PirngadiHospitals, Medan. Newborn infants with severe asphyxia (5-minuteApgar score of less than 4), fever, seizure, and maternalhypertension were excluded. Complete blood count was done bymeans of automatic cell counter (Micros (R) , Germany). Term healthyinfants were used as control subjects.Results ANC differed significantly between both groups (p=0.0001).The prevalence of early-onset neutropenia in premature infantswas 9% (95%CI 0.065;0.21). Prematurity was related with theincidence of neutropenia with a prevalence ratio of 1.1. Therewas a weak positive correlation between gestational age andANC with an r-value of 0.49 (p=0.0001).Conclusions ANC in premature infants differs from that in terminfants. The prevalence of early-onset neutropenia in prematureinfants was 9% (95%CI 0.065;0.21). Prematurity is related with theincidence of early-onset neutropenia in newborn infants. There isa correlation between gestational age and ANC
Co-Authors - Rustamaji Achmad Jajang Rukanda Akbar Tahir Arniati Arniati Bidasari Lubis Chair Rani Dachrul Aldy Dewi Lutfiana Sari Eka Priadi Erwansyah Sjarief Guslihan D Tjipta Halim Mudia Istiyah Istiyah Jamaluddin Jompa Joko Supriyanto Kartika Dian Lestari Mahmud Bakari Marhama Jelita Masruddin Masruddin Mohamad Kiki Baehaki Muhammad Taufiq El Ikhwan Muliani Panjaitan Nawir Yuslem Nina Imaniar Ria Cendana Ardhiyaningtyas Rohman Rohman ROSIHAN ANWAR Shinta Werorilangi Sulidar Sulidar Syafyudin Yusuf Syarifudin A. Wahyudi Nugroho