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Journal : Medali Jurnal : Media Dental Intelektual

PENGARUH EKSTRAK DAUN SAGA PADA PROSES PENYEMBUHAN ULKUS TRAUMATIKUS MUKOSA MULUT TIKUS PUTIH JANTAN (Rattus Novegicus) (in vivo) Ong Jonathan; Siti Chumaeroh; Moh Baehaqi; Oediani Santoso
Jurnal Medali Vol 1, No 1 (2013): Media Dental Intelektual
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/medali.v1i1.82

Abstract

Traumaticus ulcer or often called thrush is an issue that often comes up in society as it causes pain. People believe that the saga leaves can heal the ulcer. Previous research mentions saga leaves have anti-inflammatory substances.This research aims to determine the effect of Saga leaf (Abrus precatorius) against ulcerative traumatikus in vivo to Rattus Novegicus. This is experimental research which design randomized post test only control group, with Rattus Novegicus. In this research there were four group treatments. Data used to calculate the number of fibroblasts in 4 each visual field preparate. The research used statistical analysis Independent T test.The results of the average number of fibroblasts in each group were K3, K7, P3, P7 is 23.34, 18.83, 47.00, 23.83. Independent T Test obtained value of p <0.05 on day 3 but not on day 7. This means there was inhibition effect produced by extracts of saga leaves on day 3 but not on day 7.From the results, it can be concluded that the leaf extract Saga (Abrus precatorius) has an influence on ulcer healing traumatikus on Rattus Novegicus which have been shown number of fibroblasts. Key Words : Saga Leaf extract, traumatic ulcer
UJI EFEKTIFITAS EKSTRAK ANGGUR MERAH (Vitis Vinivera) TERHADAP PERTUMBUHAN CANDIDA ALBICANS SECARA IN VITRO Apriyani Suryaningsih; Siti Chumaeroh; Benni Benyamin
Jurnal Medali Vol 2, No 1 (2015): Media Dental Intelektual
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/medali.v2i1.442

Abstract

Infeksi jamur di rongga mulut banyak disebabkan oleh jamur Candida albicans yang merupakan flora normal dalam tubuh dan bersifat opertunistik. Ekstrak anggur merah memiliki aktivitas antijamur, karena memiliki kandungan flavonoid dan tannin. Tujuan penelitian ini adalah untuk mengetahui pengaruh pemberian ekstrak anggur merah berbagai konsentrasi terhadap pertumbuhan Candida albicans secara in vitro. Penelitian eksperimental laboratorium dengan post test only control group design. Sampel adalah Candida albicans dengan tingkat kepekaan sesuai dengan standar Mc Farland 0,5 yaitu 1 X 108 CFU/ml. Penelitian ini menggunakan metode cakram yang dilakukan pada satu kelompok kontrol dan empat kelompok perlakuan ekstrak anggur merah dengan konsentrasi 12,5%, 25%, 50%, dan 100%. Pertumbuhan Candida albicans di ukur dari zona hambat yang terbentuk. Uji Kruskal Wallis dan Man-Whitney di gunakan untuk melihat perbedaan rata-rata diameter zona hambat. Hasil penelitian menunjukan diameter zona hambat ditemukan pada kelompok ekstrak anggur merah konsentrasi 12,5%, 25%, 50%, dan 100%. Dengan rata-rata diameter 0,8mm,  1,26mm, 1,65mm, 2,1mm. Ke empat nilai rata-rata ini menunjukan perbedaan bermakna (nilai p=0,000). Disimpulkan bahwa semakin tinggi konsentrasi ekstrak anggur merah, semakin besar daya hambatnya terhadap pertumbuhan jamurCandida albicans.
PENGARUH DEPRESI TERHADAP TERJADINYA GINGIVITIS (Studi Terhadap Santri Pondok Pesantren Rohmatulla 2 Tahun 2012) Yessi Idha Martha; Siti Chumaeroh; Aning Susilowati; Diyah Fatmasari
Jurnal Medali Vol 1, No 1 (2013): Media Dental Intelektual
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/medali.1.1.44-48

Abstract

ABSTRACT Depression as a part of a psychological condition is a situation that interference with the natural feeling. Emotional condition can affect the secretion of saliva in oral cavity and can disrupt the balance of bacteria in the mouth and can cause disease in the oral cavity. One of the common diseases is gingivitis. The aim of this study is to determine the effect of depression on the occurrence of gingivitis at boarding school students Rohmatullah 2 in 2012.This study was used observational analytic method with cross sectional design study that was conducted on 50 students at the boarding school Rohmatullah2 in 2012 using simple random sampling method. The level of depression was measured with a questionnaire of Beck Depression Inventory (BDI). Gingival health conditions were measured by the Gingival Index. The results of research were analyzed using the Kolmogorov-Smirnovt test.The results of the data analysis with Kolmogorov-Smirnov test showed that there was a significant relationship between the level of depression and the occurrence of gingivitis (p=0.001), while the status of OHI-S as a confounding factor in this study also affect the occurrence of gingivitis (p=0.000). The existence of a significant effect of depression on the occurrence of gingivitis in accordance with a theory that depression can affect the release of cortisol from corticosteroid hormone that results in decreased production of IgA and Ig Gingingival fluid that acts as antibody in the oral cavity. In addition to the poor conditions of oral hygiene can lead the accumulation of plaque. from the accumulation of plaque can lead to the development of inflammatory diseases such as gingivitis.Based on the results of this study concluded that there was significant influence between depression and gingivitis at boarding school students Rohmatullah 2 in 2012. Keywords: Depression, Gingivitis, BDI, Gingival Index