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All Journal Jurnal Ilmu Farmasi dan Farmasi Klinik (Journal of Pharmaceutical Science and Clinical Pharmacy) Jurnal Surya Medika PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) JURNAL ILMU KEFARMASIAN INDONESIA Jurnal EDUCATIO: Jurnal Pendidikan Indonesia Journal Syifa Sciences and Clinical Research (JSSCR) ALKIMIA : Jurnal Ilmu Kimia dan Terapan Jurnal Ilmiah Pharmacy Jurnal Farmasi dan Sains Indonesia (JFSI) Medical Sains : Jurnal Ilmiah Kefarmasian Lentera Negeri Sinteza Medical Sains : Jurnal Ilmiah Kefarmasian
Tri Puspita Yuliana
Universitas Hamzanwadi
Religion Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Public Health Social Sciences Other

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Journal : Journal Syifa Sciences and Clinical Research (JSSCR)

 1 
Formulasi Sediaan Krim Ekstrak Etanol Kulit Buah Semangka Merah Sebagai Krim Antijerawat Tri Puspita Yuliana; Hasratul Kusuma; Puspawan Hariadi; Baiq Maylinda Gemantari
Journal Syifa Sciences and Clinical Research Vol 5, No 2 (2023): Volume 5 Edisi 2 2023
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/jsscr.v5i2.19590

Abstract

Acne is a problem caused by Propionibacterium acnes bacteria. Red watermelon rind contains lycopene compounds, antioxidants, has tannin and flavonoid compounds and is very good for skin care, free from acne, functions as an antibacterial. The purpose of this study was to formulate ethanol extract of red watermelon rind into anti-acne cream preparation and determine the inhibition zone and determine the red watermelon rind cream has the best antibacterial activity against Propionibacterium acnes bacteria. The method used in this study was experimental, extract concentration of 15%, 20%, 25%. The antibacterial activity test was conducted using the pitting method and evaluated the physical properties of the cream preparation including organoleptic examination, pH test, homogeneity test, adhesion test, spreadability test. The results showed that the evaluation of the physical properties of the cream preparation had characteristics in accordance with the evaluation of the preparation carried out at each concentration, including organoleptic examination, pH test, homogeneity test, adhesion test, spreadability test. The results of the antibacterial activity test of ethanol extract of red watermelon rind F1, F2, F3 are: 6.76 mm, 8.33 mm, 8.73 mm. The results of the antibacterial activity test of the cream preparation of ethanol extract of red watermelon rind F1, F2, F3 are: 4.47 mm, 6.04 mm, 8.17 mm. It can be concluded that the cream preparation of ethanol extract of red watermelon rind meets the characteristics of cream preparation stability, meets the criteria of good physical properties at concentrations of 15%, 20%, 25%, has weak to moderate category antibacterial activity against Propionibacterium acnes bacteria.
Co-Authors Aditya Noviadi Rakhmatullah Arief Rafsanjani Baiq Maylinda Gemantari Dahriah Fitri Wahyuningsih Djati Wulan Kusumo Endang Darmawan Erma Ewisa Oktresia Ersi Arviana Ihsan Evi Wardani Fatin Bariatul Ula Fitriwati Sovia Hartini Haritani Hasni Pulhehe Hasratul Kusuma Kintoko Kintoko Minawati Minawati Muhammad Irsyadul Hamdi Muhlisun Azim Novasari, Novasari Nurcholid Umam Kurniawan Nurul Fitri Erlinda Zulda Puspawan Hariadi Rudy Harjo Kusumo Shakila Shakila Sulistia Ardyati Tya Muldiyana Urmatul Waznah Yuli Nurullaili Efendi Yuyun Febriani