Article Per Year (5 Year)
p-Index From 2019 - 2024
3.625
P-Index
This Author published in this journals
All Journal Jurnal Pendidikan Sains Folia Medica Indonesiana Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan Jurnal Sport Science Kinestetik : Jurnal Ilmiah Pendidikan Jasmani JMM (Jurnal Masyarakat Mandiri) Jurnal SPORTIF : Jurnal Penelitian Pembelajaran Jurnal Sporta Saintika JOSSAE (Journal of Sport Science and Education) Jurnal Maenpo : Jurnal Pendidikan Jasmani Kesehatan dan Rekreasi Community Development Journal: Jurnal Pengabdian Masyarakat Jurnal Patriot STRADA Jurnal Ilmiah Kesehatan KORSA
Sugiharto Sugiharto
Universitas Negeri Malang
Humanities Economics, Econometrics & Finance Education Health Professions Library & Information Science Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

Published : 23 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 3 Documents
Search
Journal : KORSA

 1 
Efek Latihan Aerobik Terhadap Irisin Dalam Mencegah Obesitas Naufal Firdaus; Sugiharto Sugiharto; Desiana Merawati
KORSA: Jurnal Kajian Ilmu Keolahragaan dan Kesehatan Vol 2, No 1 (2023): Mei
Publisher : Program Studi Ilmu Keolahragaan

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Aerobic exercise is rated as the most effective strategy for treating obesity. Aerobic exercise induces irisin to stimulate tissue browning. The important role of irisin in the regulation of metabolism and reduction of body fat is that it can increase energy expenditure. The method of this article is to look at several journal articles that compare one journal to another. In practice, the results of the analysis of research journals are combined based on their respective similarities and differences to produce new conclusions. The results Aerobic exercise induces the release of irisin via peroxisome proliferation activated receptor-γ (PPAR-γ) and PGC-1α. Exercise that is performed at intervals increases PGC-1α activation, especially in the heart and skeletal muscles and improves various metabolic parameters such as insulin sensitivity and signaling, promotes AMPK activation, PGC1α phosphorylation and FNDC5 production, followed by cleavage of FNDC5 to produce irisin which will be released into the blood circulation. . The release of irisin into the blood circulation activates the AMPK pathway by reducing intracellular ATP or by increasing the intracellular calcium concentration in muscle cells, causing increased glucose and lipid uptake and increased fat metabolism. Aerobic exercise can increase irisin in an obese person which has an effect on energy expenditure so that fat in the body is reduced and subsequently results in weight loss.
Latihan Fisik & Sekresi PGC-1α Pada Obesitas Arya Dwi Prastickho; Desiana Merawati; Sugiharto Sugiharto
KORSA: Jurnal Kajian Ilmu Keolahragaan dan Kesehatan Vol 2, No 1 (2023): Mei
Publisher : Program Studi Ilmu Keolahragaan

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Peroxisome proliferator activates gamma coactivator 1α (PGC-1α) receptors associated with oxidizing activity in adipose tissue and muscle, which is the prevention of increased obesity through non-pharmacological therapy. Physical exercise is believed to be a trigger for PGC-1α secretion as a strategy to prevent an increase in the prevalence of obesity and prevent the occurrence of metabolic syndrome. Physical exercise also improves metabolic health in obese individuals. Physical exercise is also believed to increase PGC-1α levels in obese individuals. after exercise, the thermogenic gene is expected to remain active. These conditions are favorable and attractive for the browning process to maintain homeostasis in response to a decrease in the AMP/ATP ratio and increased biogenesis in mitochondria. The decrease in AMP/ATP led to active AMPK, the ratio observed 3 hours after exercise. AMPK activation triggers activation of the PGC-1α gene receptor stimulating an increase in FNDC-5, which then cleaves into circulating irisin to activate UCP-1. Consequently, PGC-1α-induced UCP-1 activation enhances browning. The method of this article is to look at several journal articles and compare one journal with another, in the sense that the results of the analysis of research journals are combined based on their similarities and differences to draw new conclusions. According to previous studies, it was also shown that moderate and high-intensity exercise was proven to increase PGC-1α levels in obese individuals, both acutely and chronically.
MEDIASI LATIHAN ANGKAT BEBAN TERHADAP PENINGKATAN EKSPRESI PGC-1α PADA REMAJA PEREMPUAN PENDERITA OBESITAS Moh. Alfino Arisandi; Desiana Merawati; Sugiharto Sugiarto
KORSA: Jurnal Kajian Ilmu Keolahragaan dan Kesehatan Vol 2, No 1 (2023): Mei
Publisher : Program Studi Ilmu Keolahragaan

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Peroxisome proliferator activated receptor-gamma coactivator 1 (PGC-1α) is closely related to metabolic status in obese patients. This study aims to analyze the response of lifting weights to increased levels of PGC-1α as a metabolic status in obese people. This study was a true experimental study with the randomized pretest-posttest control group design using 14 female adolescents aged 20-25, body mass index (BMI) 25-30 kg/m2, normal systolic blood pressure, normal resting heart rate, Percentage of body fat ≥ 30%, and divided into 2 groups randomly, namely the control group without intervention 7 subjects and the group given weight training intervention 6 subjects. PGC-1α levels were examined using the Enzyme Link Immunosorbent Assay (ELISA) kit (Cat.No.:E-EL-H6017; Elabscience, Inc., USA). Data analysis techniques using SPSS version 21.0. The results of the analysis of the average pretest and posttest PGC-1α levels in K1 (1.19 ± 0.89 vs 1.27 ± 0.65 ng/mL, p = 0.746), and K2 (1.07 ± 0.26 vs 2.60 ± 0.40 ng/mL, p = 0.000). It is recommended for future research using male and female subjects, so that the results of the study can be generalized to both sexes.
Co-Authors - Roesdiyanto Ach. Rasyad, Ach. Adi Pranoto Agnieszka Magdalena Nowak Angga Wahyu Setya Budi Arya Dwi Prastickho Deddy Whinata Kardiyanto Desiana Merawati Dwi Anggareksa Setyo Widarto Eko Hariyanto Febry Saputra Fikri Sasongko Widyatama Firly Imaniar Hartono Hartono Ido Nur Abdulloh Khumaira Marsyahidah Badu M. E. Winarno Moch Nasmay Lupita Moh Indra Kurnia Hadiputra Moh. Alfino Arisandi Muhammad Aliffajaruddin Alfani Muhammad Aufar Adfani Irawan Nabila Ainaya Mubasyiroh Naufal Firdaus Nur Ezza Fazleen Mohd Fathil Olivia Andiana Pinton Setya Mustafa Prayogi Dwina Angga Prayogi Dwina Angga Prima Suci Ibar Wati Ningrum Purwo Sri Rejeki Purwo Sri Rejeki Rias Gesang Kinanti Rixco Gesang Gumelar Sapto Adi Septyaningrum Putri Purwoto Slamet Yulianto Supriyadi Supriyadi Supriyono Supriyono Wawan Prio Kuncoro