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All Journal e-Journal Pustaka Kesehatan Jurnal Ilmu Kesehatan Masyarakat Journal of Agromedicine and Medical Sciences NurseLine Journal Asyahid Journal of Islamic and Quranic Studies (AJIQS)
Ali Santosa
Fakultas Kedokteran Universitas Jember
Religion Humanities Economics, Econometrics & Finance Education Environmental Science Health Professions Library & Information Science Medicine & Pharmacology Nursing Public Health

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Journal : e-Journal Pustaka Kesehatan

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Hubungan antara Tingkat Depresi dengan Kualitas Hidup Pasien Chronic Kidney Disease yang Menjalani Hemodialisis di RSD dr. Soebandi Jember (Correlation between Level of Depression and Quality of Life of Chronic Kidney Disease Patients During Hemodialysis Nindhya Kharisma Putri; Justina Evy Tyaswati; Ali Santosa
Pustaka Kesehatan Vol 4 No 3 (2016)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Chronic Kidney Disease (CKD) is secondary disease with irreversible process of progressive reduction in kidney function, one of the therapy is hemodialysis which can cause psychological disorders. The most frequently occured is depression that can reduce quality of life of CKD patients. The aim of this research was to analyze the correlation between level of depression and quality of life of CKD patients during hemodialysis therapy. This research used Cross Sectional Design with 30 respondents. The data were collected from hemodialysis policlynic at dr. Soebandi hospital Jember. The level of depression was measured using HDRS questionnair, and quality of life was measured using WHOQOLBREF questionnair. The result showed that 50% respondents had mild depression (23,3% respondents had good quality of life and 26,7% respondents had bad quality of life), 23,3% respondents were moderate depression (3,3% respondents had good quality of life and 20% respondents had bad quality of life), while 26,7% respondents were severe depression who had bad quality of life. The Spearman correlation test showed that the significance (p) of this test was 0.010 with -0.464 correlation coefficient (r). It can be concluded that there were correlation between level of depression and quality of life of CKD patients during hemodialysis therapy at dr. Soebandi regional hospital Jember. Keywords: Chronic Kidney Disease (CKD), depression, quality of life, hemodialysis.
Efek Ekstrak Etanol Kayu Manis (Cinnamomum burmannii) terhadap Kadar MDA Ginjal pada Tikus Wistar Hiperglikemi (The Effect of Cinnamon (Cinnamomum burmannii) Ethanolic Extract on Kidney MDA in Hyperglycemic Wistar Rats) Vidya Muqsita; Elly Nurus Sakinah; Ali Santosa
Pustaka Kesehatan Vol 3 No 2 (2015)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Cinnamon contains natural antioxidant polyphenols. Polyphenols reduces lipid peroxidation by lowering levels of MDA. This study aimed to prove the effect of ethanolic extract of cinnamon (Cinnamomum burmannii) on decreasing kidney MDA levels of rat. This research was true experimental post-test only control group design. Twenty five rats 2-3 months of age, were divided into 5 groups: K(-) without alloxan induction, K(+) was induced with alloxan 100 mg/kg, group P1, P2, and P3 were induced with alloxan 100 mg/kg and cinnamon ethanolic extract 200 mg/kg, 400 mg/kg and 600 mg/kg, respectively for 7 days. At the end of the treatment, MDA concentration of kidney was measured by using ELISA method. The average of kidney MDA level were K(-), K(+), P1, P2, and P3 grups were 1.8923 ng/g, 1.8926 ng/g, 1.8926 ng/g, 1.8925 ng/g, and 1.8926 ng/g, respectively. Data was analysed using One Way ANOVA, and resulted p = 0.238. The conclusion was cinnamon ethanolic extract could not reduce kidney MDA levels in hyperglycemic wistar rat induced with alloxan. Keywords: Cinnamomum burmannii, polyphenols, alloxan, MDA
Uji Efektivitas Beras Herbal Forte terhadap Penurunan Kadar Glukosa Darah Pasien Diabetes Melitus Tipe 2 (Study of the Herbal Rice Forte Effectiveness on Decreasing Blood Glucose of Diabetes Mellitus Type 2 Patient) Gema Akbar Wakhidana; Ancah Caesarina Novi Marchianti; Ali Santosa
Pustaka Kesehatan Vol 6 No 1 (2018)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v6i1.6789

Abstract

Diabetes mellitus is metabolic diseases characterized by hyperglycemia caused by disturbances in insulin secretion or insulin activity. Herbal Forte Rice is rice synthetic material composed of main purple sweet potato and corn flour. It contains antioksidan, fiber, resistant starch and having moderate glycemic index. This study aimed to determine the effectivity of Herbal Forte Rice on decreasing blood glucose levels of patients type 2 DM. It used a cross-over design, the role of research subjects was both as control and treatment groups. Total sample of this research consisted of 60 samples. The treatment group was given Herbal Forte Rice for 7 days in 2 consecutive meals, while the control group did not receive any intervention. The results showed the average level of Fasting Blood Glucose (FBG) beginning and end of the treatment group 179.76 mg/dL and 138.7 mg/dL; FBG beginning and end of the control 180.87 mg/dL and 187.63 mg/dL; 2 hours post prandial Blood Glucose (2hppBG) levels of beginning and end of the treatment group 284.37 mg/dL and 183.8 mg/dL; 2hppBG levels beginning and end of the control 280.57 mg/dL and 284.13 mg/dL. This study concludes that Herbal Forte Rice effective on decreasing blood glucose levels of patients type 2 DM. Keywords: diabetes mellitus, Rice Herbal Forte, GDP and GD2PP
Uji Aktivitas Protein Isolat Biji Melinjo (Gnetum gnemon) sebagai Antihipertensi secara In Vivo Kartika Tari Azhar; Tri Agus Siswoyo; Ali Santosa
Pustaka Kesehatan Vol 2 No 3 (2014)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Hipertensi merupakan suatu keadaan seseorang ketika terjadi peningkatan tekanan darah sistolik ≥ 140 mmHg dan/atau tekanan darah diastolik ≥ 90 mmHg. Pengobatan jangka panjang hipertensi menimbulkan beberapa efek samping sehingga diperlukan suatu alternatif pengobatan untuk hipertensi, misalnya dengan protein isolat biji melinjo. Penelitian ini bertujuan untuk mengetahui efek antihipertensi dari protein isolat biji melinjo pada tikus hipertensi. Tikus wistar diinduksi dengan prednison 1,5 mg/kgBB dan NaCl 2% selama 7 hari kemudian diberi perlakuan. Terdapat 7 kelompok perlakuan, kelompok K merupakan tikus normal, kelompok K(-) adalah tikus hipertensi tapi tidak diberi perlakuan, kelompok K(+) adalah tikus hipertensi dan diberi kaptopril 2,5 mg/kgBB pada hari ke-8, kelompok P1, P2, P3, dan P4 merupakan tikus hipertensi dan masing-masing diberikan protein isolat biji melinjo dengan dosis 5 mg/kgBB, 10 mg/kgBB, 20 mg/kgBB, dan 30 mg/kgBB pada hari ke-8. Tekanan darah diukur sebelum dan setelah diberi perlakuan tiap 1 jam selama 5 jam. Data dianalisis secara statistik menggunakan uji Kruskal Wallis dan Mann. Dari hasil penelitian menunjukkan bahwa protein isolat biji melinjo tidak dapat menurunkan tekanan darah tikus model hipertensi.   Kata kunci: Antihipertensi, Gnetum gnemon, Protein Isolat, Tekanan Darah 
Co-Authors . Suryono Ancah Caesarina Novi Marchianti Athiyah Fi Ramadani Ayi Yunus Rusyana Dimes Atika Permanasari Dini Agustina Dwita Aryadina Rachmawati Elly Nurus Sakinah, Elly Nurus Gema Akbar Wakhidana Giovani Gianosa Justina Evy Tyaswati Kartika Tari Azhar Mega Ratnasari Nindhya Kharisma Putri Pipiet Wulandari Rinda Yanuarisa Tri Agus Siswoyo Vidya Muqsita Yadi Janwari