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All Journal Journal of Agromedicine and Medical Sciences UNEJ e-Proceeding Pharmascience Indonesian Journal of Cardiology Indonesian Journal of Medicine Jurnal Ilmiah Kesehatan Journal of Health Sciences
Pipiet Wulandari
Fakultas Kedokteran Universitas Jember
Education Health Professions Medicine & Pharmacology Nursing Public Health

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Association between Left Ventricular Global Longitudinal Strain and Functional Capacity Measured with Six-Minutes Walk Test in Patients after Acute Myocardial Infarction. Wasyanto, Trisulo; Wulandari, Pipiet; Purwaningtyas, Niniek; Murti, Bhisma
Indonesian Journal of Medicine Vol 2, No 3 (2017)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (481.08 KB)

Abstract

Background: The ischemia resulting from critical coronary narrowing or total occlusion first affects the subendocardialmyofibers. Thus, abnormalities in longitudinal function can be detected before reductions in LVEF and reflects infarct size. The 6MWT provides information that may be a better index of the patients ability to perform daily activities. This study was to assess the relationship between left ventricular (LV) global longitudinal strain (GLS) and functional capacity measured with 6 minute walk test (6MWT) after AMI.Subjects and Method: This is a cross sectional study of patients with STEMI and NSTEMI, at Moewardi Hospital, Surakarta. Eligible patients underwent echocardiography global longitudinal 2D-STE that performed within 48 hour of admission and 6MWT pre- discharge or at the first follow-up visits (day 4-9). Patients were divided into 2 groups according to the LV GLS value, patients with substantial infarction (LV GLS > -13.8%) and non-substantial infarction (LV GLS < -13.8%).Results: There were 50 patients with 42 STEMI and 8 NSTEMI. Compared to patients in group LV GLS < -13.8% (n=18), patients in group LV GLS > -13.8% (n=32) were more likely to be older (57.6 y.ovs 55 y.o), less in functional capacity (10.17 1.3 ml/kg/min vs 11.04 0.98 ml/kg/min; p= 0.018) and less in 6 MWT distance (347.97 65.49 m vs392.39 49.44 m; p=0.016). Using ROC curves, the 6 MWT distance cutoff value of 375 m identified patients with LV GLS >-13.8%, sensitivity of 72.2% and specificity 65.6%, respectively with AUC= 0.70 (CI 95%; 0.559-0.852; p= 0.017). However, LV GLS >-13.8% and age >60 y.o remained the independent predictor in a multivariate logistic regression analysis to identify 6 MWT distance < 375 m in patients after AMI with GLS >-13.8%, (OR =7.967; CI 95%= 1.669-38.030; p=0.009) and age >60 y.o, (OR=10.898; CI95%= 2.201-53.971; p=0.003).Conclusions: In patients after AMI with substantial infarction (LV GLS >-13.8%) had less in functional capacity. The 6 MWT distance cutoff value of 375 m identified patients with LV GLS >-13.8% and could be used in rehabilitation program after AMI.Keywords: Acute Myocardial Infarction, LV Global longitudinal strain, functional capacity, 6 MWT.Correspondence:Trisulo Wasyanto. Department of Cardiology and Vascular Medicine, Faculty of Medicine, Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami No. 36 A, 57126, Surakarta, Central Java.Indonesian Journal of Medicine (2017), 2(3): 192-206https://doi.org/10.26911/theijmed.2017.02.03.07
The Difference Incidence of Maternal Uterine Inertia Between Labor With and Without Anemia in Hospital of dr. Soebandi Jember Dina Ayu Savitri; Yonas Hadisybroto; Pipiet Wulandari
Journal of Agromedicine and Medical Sciences Vol 5 No 3 (2019)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v5i3.9514

Abstract

One of the indirect causes of maternal death is anemia. Anemia in pregnancy is a woman with a hemoglobin level below 11 g / dl caused by iron deficiency in pregnant women so that the hemoglobin level becomes low and cannot meet the need for oxygen to perfusion to the tissues. This consumes energy in the affected muscles and buildup of lactic acid which causes fatigue and reduced muscle contraction during labor. Inadequate uterine contractions are called uterine inertia and are characterized by a prolonged phase of labor, which is weak, rarely and short duration. The purpose of this study was to determine the differences in the incidence of uterine inertia between labor and anemia released in RSD dr. Soebandi Jember. This study was analytic observational with a cross sectional research design. The study population was all pregnant women who had improved labor and were included in the medical record at RSD Dr. Soebandi Jember period January 1, 2017 - December 31, 2017. Samples from this study were mothers who had approved the delivery and fulfilled the inclusion and exclusion criteria that had been determined until the number of samples could be fulfilled. The number of samples in this study were 76 samples. The type of data used in this study is secondary data obtained by researchers from the medical records of pregnant women who have received labor. The data included in this study contain demographic data consisting of the age of pregnant women and parity, clinical data in the form of uterine inertia and laboratory data consisting of anemia status. In analyzing the data with Chi Square test (X²), a significance value of 0.011 was obtained so that it can be concluded that Ho is rejected and Ha is accepted which means that the incidence of uterine inertia between free labor and anemia is not important in RSD Dr. Soebandi Jember. Keywords: anemia, uterine inertia, pregnancy, age, parity.
Association Between Risk Factors with The Event of Nasopharynx Carcinoma in Soebandi Hospital Period Of January 2017- March 2019 Emda Zein Cik Fitria; Nindya Shinta Rumastika; Pipiet Wulandari
Journal of Agromedicine and Medical Sciences Vol 6 No 3 (2020)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v6i3.13814

Abstract

Abstract Nasopharyngeal carcinoma is the highest malignancy in the head and neck regio. The cause of nasopharyngeal carcinoma is unknown, but there are several risk factors that can trigger nasopharyngeal carcinoma which include age, gender, genetics, occupation, geographical location, consumption of salted fish, consumption of grilled fish / grilled meat, consumption of canned foods and smoking. This study aims to determine the risk factors that influence the incidence of nasopharyngeal carcinoma. The type of this study is a obervasional analysis with a case control design carried out on 40 samples that fulfilled the inclusion and exclusion criteria. The instrument of this research is in the form of medical record recapitulation and structured interviews. The bivariate test results were age (p=0.043), sex (p=1,000), genetics (p=0.044), occupation (p=0.740), geographical location (p= 1,000), consumption of salted fish (p = 0.004) , consumption of grilled fish / grilled meat (p=0.007), consumption of canned foods (p = 0.106) and smoking (p = 0.527). The multivariate test results were the consumption of salted fish with a value (p = 0.004), consumption of salted fish / grilled meat (p = 0.023), genetic (p = 0.062), and age (p = 0.264). The conclusion of this study is the consumption of salted fish, consumption of grilled fish / grilled meat, genetics and age have a significant relationship with the event of nasopharyngeal carcinoma and the most influential relationship is the consumption of salted fish. Keywords: nasopharyngeal carcinoma, risk factor, dr. Soebandi hospital
Risk Factors Analysis of Hypertension Incidence at Karangtengah Public Health Center, Wonogiri Regency Atina Robbiatul Azizah; Angga Mardro Raharjo; Inke Kusumastuti; Cholis Abrori; Pipiet Wulandari
Journal of Agromedicine and Medical Sciences Vol 7 No 3 (2021)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v7i3.23979

Abstract

Hypertension is the most common disease found in Karangtengah Health Center, Wonogiri Regency. The incidence of hypertension can be influenced by factors such as: factor that can not be changed consists of age, gender, family history of illness and modifiable factors consisted of obesity, occupation, and smoking history. Of these risk factors, still unknown factors which increse the incidence of hypertension in Karang Tengah Public Health Center. The purpose of this study was to determine the relationship of these risk factors with the incidence of hypertension and the determinants of the incidence of hypertension in Karangtengah Public Health Center, Wonogiri Regency. This type of research is analytic observational with a cross-sectional design. The sample of this study used the total sampling method, namely all medical record data of new adult patients (>26 years) with a history of chronic diseases who came to Karangtengah Public Health Center, Wonogiri Regency in October 2020 and this study was conducted in March 2021. There were 76 patients. Most of the patients had hypertension (n=42; 55.3%), including the category of elderly (n=55; 72.4%), women (n=41; 53.9%). More patients had a family history of disease (n=50; 65.8%), were obese (n=40; 52.6%), had minimal work activities (n=44; 57.9%), and had a history of smoking (n=42; 55.3%). The risk factors associated with the incidence of hypertension were age, gender, family history of disease, BMI, occupation, and smoking history (all p<0.05). Keywords: Hypertension, age, family history, BMI, occupation
Comparative Effectiveness of Corn Oil (Zea mays) with Pure Coconut Oil (Cocos nucifera L.) to Reduced Glucose Blood Levels of Alloxane Injected Wistar Rats Khadijah Nur Al Firdausi; Sugiyanta Sugiyanta; Pipiet Wulandari
Journal of Agromedicine and Medical Sciences Vol 3 No 3 (2017)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v3i3.6193

Abstract

Epidemiological studies show an increased incidence of diabetes mellitus. The initial therapy of diabetes mellitus is a diet treatment. The recommended intake of fat is a Saturated Fatty Acids (SFA) <7% and a Polyunsatturated Fatty Acid (PUFA) <10% of calories. The corn oil contains PUFA and the virgin coconut oil contains SFA as the main component. Aims of this study was to compare the effectivity of corn oil (Zea mays) and virgin coconut oil (Cocos nucifera L.) in decreasing blood glucose level in alloxane-ijnected wistar rats. This was a laboratory experiment research, used the posttest-only control design. The negative control group was wistar rats injected by aquabidest and standard feed diet (K-); the positive control group was alloxane-injected rats with standard feed diet (K+); alloxane-injected rats with standard food diet and 0.54 mL of corn oil/day for 28 days were P1 group; alloxane-injected rats with standard diet food and 0.54 mL of virgin coconut oil/day for 28 days were P2 group. Statistical analysis using the one way ANOVA test showed that the corn oil and virgin coconut oil decrease blood glucose level, but there was no significantly difference in decresing of blood glucose level between P1 and P2. This study concluded that the corn oil and the virgin coconut oil have the same effectiveness in decreasing blood glucose level in wistar rats injected with alloxane.Keywords: Corn oil, virgin coconut oil, blood glucose level, alloxane
The Relationship Between Body Mass Index and Student Body Ability Index of Medical Faculty Jember University Adelia Handoko; Aris Prasetyo; Pipiet Wulandari; Kristianingrum Dian Sofiana; Jauhar Firdaus; Karisma Adya Pertiwi
Journal of Agromedicine and Medical Sciences Vol 7 No 3 (2021)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v7i3.23785

Abstract

Technological advances in recent years have had an impact on people's lifestyles. Almost all activities in various sectors can be carried out and accessed via smartphones. This causes a decrease in physical activity which can lead to obesity. Obesity is an imbalance of energy entering the energy used in the body resulting in the accumulation of excess lipids which can interfere with the health condition of the body. Body composition is an important part of determining one's physical fitness. Body composition can be seen from a person's Body Mass Index (BMI). This type of research is analytic observational with cross sectional research design. The data used by researchers is secondary data in 2018. The sampling technique used is purposive sampling. The sample used in this study was 127 people, consisting of 47 men and 84 women. Data were analyzed using SPSS version 26 through the Spearman Analysis Test with the results of p = 0.000 (p-value <0.05) for the relationship between BMI and IKB in the slow way and p = 0.002 (p-value <0.05) for the relationship between BMI with IKB the fast way. The conclusion that can be drawn from the results of the analysis is that there is a weak correlation between body mass index and body fitness index on the Havard Step Test fitness test for students of the Faculty of Medicine, University of Jember. Keywords: body mass index, harvard step test , physical fitness
Ventricular Septal Rupture in ST-Elevation Myocardial Infarct in Low Resource Setting: a case series Suryono Suryono; Naesilla Naesilla; Jarwoto Roestanajie; Dwi Ariyanti; Pipiet Wulandari
Jurnal Kardiologi Indonesia Vol 41 No 4 (2020): Indonesian Journal of Cardiology: October - December 2020
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.1062

Abstract

Background: The mortality rate caused by myocardial infarct (MI) escalates in the presence of ventricular septal rupture (VSR). This article aimed to analyze clinical factors that might be valuable as predictors of VSR. Case Illustration: We found and presented six documented post-infarction VSR out of 1,613 MI cases between January 2015 to December 2019. Conclusion: Based on the analysis, clinicians should be aware of these factors as they were potential to be the predictors: advanced age, first MI, anterior location of the infarct, infranodal conduction disorder, no reperfusion treatment, high systolic blood pressure on admission, and no smoking history.
Hygiene Sanitasi Lingkungan dalam Potensi Pembentukan Kader Sehat Mandiri Pesantren Nuris Jember Adistha Eka Noveyani; Ancah Caesarina Novi Marchianti; Pipiet Wulandari
Jurnal Ilmiah Kesehatan Vol 13 No 2 (2020): Jurnal Ilmiah Kesehatan (Journal of Health Science)
Publisher : Universitas Nahdlatul Ulama Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (228.637 KB) | DOI: 10.33086/jhs.v13i2.1484

Abstract

Latar belakang: Pondok pesantren merupakan tempat berkumpulnya para santri dari berbagai daerah. Tempat ini dikenal memiliki banyak problematika kesehatan, mulai dari kebersihan diri hingga kebersihan lingkungan. Kebersihan lingkungan sekitar maupun di dalam kamar ditentukan oleh kebiasaan sehari-hari santri. Kurangnya kepedulian dalam menjaga kebersihan lingkungan dapat berisiko munculnya penyakit, diantaranya scabies (gudik). Tujuan: untuk mengetahui pengetahuan, sikap dan perilaku santri di kawasan pondok terkait kejadian scabies sebagai analisis dasar pemberian training kader kesehatan. Metode: Ini merupakan jenis penelitian deskriptif kuantitatif dengan pengumpulan data wawancara terstruktur dengan kuesioner. Sampel penelitian ini adalah siswa-siswi SMA/MA Unggulan Nuris yang tergabung dalam ekstrakurikuler PMR. Penelitian dilakukan Oktober-November 2019 di SMA/MA Unggulan Nuris Jember. Hasil: Hasil studi ini menunjukkan bahwa sebagian besar responden memiliki pengetahuan yang baik terkait kebersihan diri dan lingkungan. Juga sebagian besar sikap mereka cenderung setuju terhadap aktivitas kebersihan diri dan lingkungan. Namun, dalam hasil perilaku/kebiasaan sehari-hari mereka, terdapat beberapa hal yang perlu menjadi perhatian. Sebagian besar (73%) santri saling meminjam sarung/kerudung dengan temannya; dan sebagian besar (57%) masih sesekali saling pinjam pakaian dengan temannya; juga masih ada yang saling meminjam peralatan mandi pribadi seperti sabun mandi, sikat gigi, dan handuk; hampir sebagian (43%) siswa menggunakan pakaian yang sama lebih dari 1 hari; hampir sebagian (47%) juga tidak mandi setelah beraktivitas/berolahraga; dan hampir sebagian (47%) hanya sesekali menebah tempat tidur saat setelah maupun hendak ditiduri. Oleh karena itu kebiasaan tersebut perlu diubah. Perilaku dapat diubah dengan adanya keteladanan dari sesama santri yang ditunjuk menjadi kader kesehatan agar santri tahu, mau dan mampu hidup bersih dan sehat. Selanjutnya dilakukan training terhadap anggota PMR yang kemudian menjadi kader kesehatan dalam upaya pengendalian kebersihan lingkungan dan menekan angka kejadian scabies di pondok pesantren. Kesimpulan dan rekomendasi: meskipun memiliki pengetahuan dan sikap yang cukup baik, namun beberapa perilaku santri masih berpotensi dalam meningkatnya kejadian scabies atau penyakit kulit lainnya. Diharapkan ada pemantauan berkala terhadap kebersihan lingkungan dan perilaku santri setelah dilakukan training dan dibentuknya kader kesehatan.
Hubungan Aktivitas Fisik dan Indeks Massa Tubuh dengan Gangguan Muskuloskeletal pada Mahasiswa Kedokteran Universitas Jember di Masa Pandemi Covid-19 Muhammad Ihwan Narwanto; Syadza Salsabila; Pipiet Wulandari
Jurnal Ilmiah Kesehatan Vol 21 No 1 (2022): Jurnal Ilmiah Kesehatan terbitan Maret Volume 21 Nomor 01 Tahun 2022
Publisher : STIKIM Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33221/jikes.v21i1.1557

Abstract

Pandemi COVID-19 mengakibatkan terjadinya perubahan gaya hidup, terjadi penurunan tingkat aktivitas fisik dan peningkatan indeks massa tubuh. Diketahui bahwa aktivitas fisik dan indeks massa tubuh merupakan faktor resiko terjadinya gangguan muskuloskeletal. Perkuliahan daring menurunkan aktifitas fisik dan meningkatkan waktu duduk. Tujuan penelitian ini untuk mengetahui hubungan antara aktivitas fisik dan indeks massa tubuh dengan gangguan muskuloskeletal pada mahasiswa kedokteran Universitas Jember di masa pandemi COVID-19. Penelitian dengan metode cross sectional yang diikuti oleh 248 mahasiswa Fakultas Kedokteran Universitas Jember. Kuisiouner digunakan untuk menilai perubahan aktifitas fisik sebelum dan saat pandemi, aktifitas fisik dan indeks massa tubuh saat pandemi. Kuesioner dibagikan secara online pada 27 Maret - 12 April 2021. Data dianalisis menggunakan uji deskriptif dan uji chi square. Perubahan aktivitas fisik mahasiswa sebelum dan saat pandemi, yaitu 69,4% mengalami penurunan aktivitas fisik, 19,4% tetap, dan 11,3% mengalami kenaikan aktivitas fisik. Tingkat aktivitas fisik mahasiswa saat pandemi, yaitu 40,3% aktifitas fisik sedang, 33,9% aktifitas fisik rendah, dan 25,8% aktifitas fisik tinggi. Indeks massa tubuh mahasiswa, 61,7% normal, 14,5% gemuk berat, 10,5% kurus ringan, 9,7% gemuk ringan dan 3,6% kurus berat. Sebanyak 67,3% mahasiswa mengalami gangguan muskuloskeletal dengan lokasi terbanyak di pinggang (66,5%), punggung (60,5%), dan leher atas (58,7%). Dari uji chi-square diketahui bahwa terdapat hubungan signifikan antara tingkat aktivitas fisik dan perubahan aktivitas fisik sebelum dan saat pandemi dengan gangguan muskuloskeletal dengan nilai p=0,034 dan p=0,047, sedangkan hubungan antara indeks massa tubuh dengan gangguan muskuloskeletal tidak signifikan (p=0,766). Kesimpulan penelitian adalah aktivitas fisik mahasiswa kedokteran Universitas Jember di masa Pandemi Covid-19 berhubungan dengan terjadinya gangguan musculoskeletal, sedangkan tidak demikian untuk indeks massa tubuh.
Effective Dose of Moringa Leaf Extract (Moringa oleifera Lamk.) to Descrease Total Cholesterol Levels in Streptozotocin-Induced Male Wistar Rats Pipiet Wulandari; Athiyah Fi Ramadani; Suryono Suryono; Ali Santosa
Journal of Agromedicine and Medical Sciences Vol 8 No 2 (2022)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v8i2.27402

Abstract

Lipid metabolic disorder in hyperlipidemia characterized by an increase in the entire lipid profile in the blood. In 2019, the global prevalence of hyperlipidemia was 64.2%. Many patients with diabetes mellitus developed to hyperlipidemia. Diabetes mellitus characterized by hyperglycemia that caused by insulin production defects or decreased insulin resistance. Hyperglycemia in this study resulted from the injection of a streptozotocin dose of 45mg/kgBB intraperitoneally. Hyperglycemia could induced hyperlipidemia. It is due to increased lipid synthesis resulting in overproduction of HMG-CoA and ROS. Moringa leaves contain active substances such as flavonoids and vitamin C that act as antioxidants. This study was conducted to find out the effective dose of moringa leaf extract to lower the total cholesterol levels of male Wistar rats induced by streptozotocin. The dose of moringa leaf extract was divided into 5 groups, namely 62.5 mg/kgBW, 125 mg/kgBW, 250 mg/kgBW, 500 mg/kgBW, and 1000 mg/kgBW. The analysis of the data in this study was a Pearson correlation test that showed p< 0.05. It demonstrated that administration of moringa leaf extract correlated with decreased cholesterol levels of male Wistar rats. The effective dose of moringa leaf extract was calculated using a linear regression test. The equation obtained from the regression test was y= 0.0739x + 153.59, so the dose of moringa leaf extract that effectively lowers the total cholesterol levels of male Wistar rats was 528.96 mg/kgBW. Keywords: hyperlipidemia, diabetes mellitus, cholesterol, Moringa oleifera Lamk., streptozotocin
Co-Authors . Suryono Adelia Handoko Adistha Eka Noveyani Ali Santosa Alif Kufari Ancah Caesarina Novi Marchianti Angga Mardro Raharjo Athiyah Fi Ramadani Atina Robbiatul Azizah Bhisma Murti Cholis Abrori, Cholis Dina Ayu Savitri Dwi Ariyanti Emda Zein Cik Fitria Inke Kusumastuti Jarwoto Roestanajie Jauhar Firdaus Karisma Adya Pertiwi Khadijah Nur Al Firdausi Kristianingrum Dian Sofiana Kristianingrum Dian Sofiana M. Ihwan Narwanto Miranda Dewi Naesilla Naesilla Nindya Shinta Rumastika Prasetyo, Aris Purwaningtyas, Niniek septa surya wahyudi, septa surya Sugiyanta Sugiyanta Suryono Suryono Syadza Salsabila Wasyanto, Trisulo Yonas Hadisybroto