Mutia Lailani
Fakultas Kedokteran Universitas Andalas

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Gambaran Tekanan Darah Tikus Wistar Jantan dan Betina Setelah Pemberian Diet Tinggi Garam Mutia Lailani; Zulkarnain Edward; Rahmatina B Herman
Jurnal Kesehatan Andalas Vol 2, No 3 (2013)
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v2i3.154

Abstract

AbstrakHipertensi masih menjadi masalah kesehatan di dunia. Penyebabnya diduga berkaitan dengan diet tinggi garam. Tujuan Penelitian ini ialah untuk mengetahui gambaran tekanan darah tikus Wistar setelah pemberian diet tinggigaram. Penelitian ini adalah eksperimental dengan post-test only control group design. Subjek penelitian terdiri dari 10 ekor tikus Wistar jantan dan 10 ekor betina yang dibagi menjadi kelompok kontrol (K) dan kelompok perlakuan (P). Diet tinggi garam (NaCl8%, 3ml/hari) diberikan pada kelompok P selama empat minggu. Hasil penelitian menunjukkan bahwa terjadi peningkatan tekanan darah yang bermakna pada kelompok P bila dibandingkan dengan kelompok K, yaitu tekanan darah sistolik (TDS) 191±17mmHg (P) dan 168±16mmHg (K) (p<0,05), tekanan darah diastolik (TDD) 162±17mmHg (P) dan 139±13mmHg (K) (p<0,05), tekanan arteri rata-rata (TAR) 176±17mmHg (P) dan 156±15mmHg (K) (p<0,05). Peningkatan TDS dan TDD hanya terjadi pada tikus jantan, tidak pada tikus betina. Pada tikus jantan TDS 185±13mmHg (P) dan 159±9mmHg (K) (p<0,05), TDD 159±18mmHg (P) dan 131±10mmHg (K) (p<0,05), TAR 172±16mmHg (P) dan 150±15mmHg (K) (p>0,05). Pada tikus betina TDS 197±19mmHg (P) dan 178±16mmHg (K) (p>0,05), TDD 165±18mmHg (P) dan 148±11mmHg (K) (p>0,05), TAR 181±18mmHg (P) dan 162±14mmHg (K) (p>0,05). Kesimpulan studi ini adalah peningkatan tekanan darah setelah pemberian diet tinggi garam hanya terjadi pada tikus jantan.Kata kunci: diet tinggi garam, tekanan darah, hipertensiAbstractHypertension remains a health problem in the world. The cause is believed to be related to the high-salt diet. The purpose of this studi was to describe the blood pressure of Wistar rats after administration of high-salt diet. This research was experimental with post-test only control group design. Ten male and ten female Wistar rats were divided into two groups: control group(K) and treated group(P). High-salt diet (8%NaCl, 3ml/day) was given to the P group for four weeks. Blood pressure increased significantly in group P compared to group K, systolic blood pressure (SBP) 191±17mmHg (P) and 168±16mmHg (K) in (p<0.05), diastolic blood pressure (DBP) 162±17mmHg (P) and 139±13mmHg (K) in (p<0.05), mean arterial pressure (MAP) 176±17mmHg (P) and 156±15mmHg (K) in (p<0.05). The increase in SBP and DBP only occurred in male rats, not in female rats. In male rats, SBP were 185±13mmHg (P) and 159±9mmHg (K) in (p<0.05), DBP were 159±18mmHg (P) and 131±10mmHg (K) in (p<0.05), MAP were 172±16mmHg (P) and 150±15mmHg (K) in (p>0.05). In female rats, SBP were197±19mmHg (P) and 178±16mmHg (K) in (p>0.05), DBP were 165±18mmHg (P) and 148±11mmHg (K) in (p>0.05), MAP were 181±18mmHg (P) and 162±14mmHg (K) in (p>0.05). The conclusion of this study is an increase of blood pressure after the administration of high-salt diet only occured in male rats.Keywords: high-salt diet, blood pressure, hypertension
Peningkatan Pelayanan Kesehatan Lansia Melalui Pembinaan Kader Kesehatan Puskesmas Padang Kandis, Kab. 50 Kota Sumatera Barat Miftah Irramah; Afriwardi Afriwardi; Arni Amir; Fika Tri Anggraini; Lili Irawati; Yose Ramda Ilhami; Rahmat Syawqi; Mutia Lailani; Desy Nofita Sari
Poltekita: Jurnal Pengabdian Masyarakat Vol. 4 No. 3 (2023): Juli-September
Publisher : Pusat Penelitian & Pengabdian Masyarakat Poltekkes Kemenkes Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33860/pjpm.v4i3.2003

Abstract

As the global population increases, the need for effective elderly care becomes increasingly urgent. Health cadres play a crucial role in improving the health and well-being of communities. One of the strategies to address this need is training health cadres, who can serve as vital links between healthcare providers and the elderly. In this training program, we aimed to enhance the role of health cadres in elderly care to support the physical, mental, and social well-being of the elderly. Through interactive exercises and providing health cadre pocketbooks, participants learned how to assess the individual needs of the elderly and increase their motivation to visit nearby healthcare facilities, thus improving the health status of the elderly in the region of Nagari Padang Kandis, district of 50 Kota. The activity involved 15 elderly health cadres. This training showed a 25% increase in the cadres' knowledge, as improved pre-test and post-test scores indicated. The health cadres now possess the skills and knowledge to effectively support the elderly community in their environment, fostering an independent and active elderly population in their daily activities and reducing dependence on the productive-age population. Furthermore, this community engagement activity, involving collaboration between the academic community of the Faculty of Medicine, Universitas Andalas, and the Padang Kandis health center, will be conducted periodically to enhance the health status of the local individuals in their society life.