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Journal : JUMANTIK (Jurnal Ilmiah Penelitian Kesehatan)

Perbandingan Tingkat Keparahan Infeksi Primer Virus Dengue Serotipe 1, 2, 3 dan 4 di Indonesia: Systematic Review Mardhatillah Sariyanti; Nur Fitri; Ety Febrianti; Annelin Kurniati; Debie Rizqoh
JUMANTIK (Jurnal Ilmiah Penelitian Kesehatan) Vol 6, No 1 (2021)
Publisher : Prodi Kesehatan Masyarakat Fakultas Kesehatan Masyarakat UIN Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (894.767 KB) | DOI: 10.30829/jumantik.v6i1.7766

Abstract

Dengue virus infection (DENV) circulates in various hyperendemic and endemic areas that has increase mortality year by year. Indonesia is the second-largest country which is endemic to dengue infection between 30 other countries in the world. There are four circulating dengue virus (DENV) serotypes, namely DENV-1, DENV-2, DENV-3, and DENV-4. Each serotype shows a different clinical manifestation and severity. This systematic review aims to compare the severity of dengue virus primary infection and  serotype 1,2,3,and 4. Data were collected based on studies of the severity of primary infections caused by various DENV serotypes in Indonesia. Data was searched using a database in the form of Pubmed and Chocrane. The keywords used are (Primary dengue infection OR dengue primary infection) AND (serotype OR serogroup OR serotype dengue)) AND (severity OR severe dengue* OR severity of illness index* OR clinical manifestations OR clinical features OR clinical characteristics) AND Indonesia. Based on search results, we obtained 7 studies out of 699 studies. 7 studies found that there are differences in serotype circulation in Indonesia. DENV-3 is dominant in 7 cities in Indonesia, while DENV-1 is dominant in Surabaya, Bali, and Jambi. Dengue fever shows a greater percentage than DHF / DSS. The proportion of severity is lower in primary infections. 
Potensi Bakteri Endofit Andaliman (Zanthoxylum Acanthopodium DC.) Menghambat Bakteri Penyebab Infeksi pada Manusia Debie Rizqoh; Wulan Okta Kumala; Sipriyadi Sipriyadi; Besly Sinuhaji; Oktoviani Oktoviani
JUMANTIK (Jurnal Ilmiah Penelitian Kesehatan) Vol 6, No 3 (2021)
Publisher : Prodi Kesehatan Masyarakat Fakultas Kesehatan Masyarakat UIN Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (956.07 KB) | DOI: 10.30829/jumantik.v6i3.8866

Abstract

Endophytic bacteria are a beneficial bacteria that live in plant tissue. Several studies have shown that certain endophytic bacteria can produce secondary metabolites that have health effects. The andaliman (Zanthoxylum acanthopodium DC) have several properties, one of which is as antibacterial against pathogenic bacteria. The most common bacterial infections in humans are caused by commensal bacteria in the body such as Escherichia coli and Staphylococcus aureus. This study used a qualitative data collection method with the type of experimental laboratory research to isolate the endophytic bacteria andaliman which had been tested against the pathogenic bacteria Escherichia coli and Staphylococcus aureus. The initial stage were isolation of endophytic bacteria and observation of colony characteristics, after obtaining isolates with different colony characteristics, a Gram stain test and a antagonist test for pathogenic bacteria were carried out. In this study, 252 colonies grew and there were 85 isolates with different colony characteristics. From all the isolates, there were two isolates that could inhibit the growth of Escherichia coli and seventeen isolates that could inhibit the growth of Staphylococcus aureus.