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Journal : Jurnal Biologi Tropis

Ethnobotanical Study of Medicinal Plants Used to Treat Degenerative Disease in East Lombok Dyke Gita Wirasisya; Nisa Isneni Hanifa; Wahida Hajrin
Jurnal Biologi Tropis Vol. 20 No. 3 (2020): September - Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v20i3.2119

Abstract

Degenerative diseases have become a complex problem around the world. Until now, degenerative diseases have become the biggest cause of death in the world. Approximately, 17 million people die early each year due to the global epidemic of degenerative diseases. Peoples in developing countries still rely on medicinal plants for primary health care. The knowledge for medicinal plant were passed down through generation with little written documentation. This study aimed to document the indigenous medicinal plants used for the treatment for degenerative diseases in East Lombok, Indonesia and to find leads on prospective plants for further ethnopharmacology research based on quantitative ethnobotany index. The ethnomedicinal data were collected through interview and discussion among local healers and plant collected with the help of local guide also herbarium was made to aid specimen confirmation. Ethnomedicinal data was analyzed using use value (UV) along with fidelity level (FL). A total of 20 informants (traditional healers) were interviewed and from the study we can documented the use of 63 plants for the treatment of degenerative diseases. The UV ranged from 0,05 (Sesbania grandiflora) to 0,35 (Carica papaya), while the highest FL (100%) was found for 29 species. Based on the ethnobotanical index (UV and FL) from each plant we can recommend 15 species for further ethnopharmacological study to determine their therapeutic effects and mechanism of action. This study revealed rich ethnomedicinal knowledge from the community in East Lombok for the treatment of degenerative disease. 
Application of Simplex Lattice Design Method on The Optimisation of Deodorant Roll-on Formula of Ashitaba (Angelica keiskei) Wahida Hajrin; Windah Anugrah Subaidah; Yohanes Juliantoni; Dyke Gita Wirasisya
Jurnal Biologi Tropis Vol. 21 No. 2 (2021): Mei - Agustus
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v21i2.2717

Abstract

Ashitaba is known to have antioxidant activity and gram-positive antibacterial activity that causes body odor. This is the potential activity for an active substance to be developed as deodorant. The appropriate formula is needed, so it is necessary to optimize the formula using the right method. This study aimed was to determine the application of the simplex lattice design method on the optimization of a deodorant roll-on formula of ashitaba extract. Ashitaba was extracted by the maceration method. The formula optimization design was determined using the simplex lattice design method by Design Expert®7.5.1. The components for optimization were the concentration of carbopol and concentration of TEA, and the optimization parameters were the spreadability test, sticky power, and pH test. The optimum formula of deodorant consists of 0.45% carbopol and 2.05% TEA. The responses of optimum formula obtained spreadability test 6.32 ± 0.33 cm, sticky power 44.67 ± 3.94 seconds, and pH 7.73 ± 0.17. These results meet the criteria for good preparation but need further testing related to the effectiveness of the preparation and the level of acceptance of the preparation by the user.
Anti-Stapylococcus Epidermidis of Methanolic Extracts from Some East Lombok Medicinal Plants Dyke Gita Wirasisya; Amni Hamid; Muhamad Haikhal; Agriana Rosmalina Hidayati; Anggit Listyacahyani Sunarwidhi; Nisa Isneni Hanifa
Jurnal Biologi Tropis Vol. 23 No. 2 (2023): April-June
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v23i2.4732

Abstract

Wounds are structural and functional disruptions of the skin that occur as a result of an injury. Wound healing is a complex tissue repair or remodelling process in response to the injury. The most common factor that causes wounds not properly heal is infection. An infection develops when microorganisms enter the body, multiply, and trigger an immune reaction in the body. This study aims to determine the activity of Jatropha multifida L., Stachytarpheta jamaicensis (L.) Vahl, Centella asiatica (L.) Urb., Euphorbia pulcherrima Willd. ex Klotzsch, and Angelica keiskei (miq.) Koidz has long been used to treat and manage wounds in East Lombok. The plants were dried and macerated with methanol; excessed solvent was evaporated. Disc diffusions were used to determine the antibacterial activity of the plant extracts. All extracts were tested against Staphylococcus epidermidis, a common cause of wound infection. Statistically, the activity of Jatropha multifida (5;10 mg/mL), Stachytarpheta jamaicensis (10 mg/mL), Centella asiatica (10 mg/mL), Euphorbia pulcherrima (M) (5, 10 mg/mL), and Angelica keiskei (2,5; 5; 10 mg/mL) extracts were comparable with positive control. However, Angelica keiskei has a wider inhibition zone than other extracts. This discovery could be served as a basis for using plants to aid wound healing, especially to combat the interference bacteria. However, further research is needed to discover the active phytochemicals involved in the antibacterial and wound healing process.