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Outcomes Prediction Using qSOFA, SpO2 / FiO2 and Procalcitonin of Pneumonia Sepsis Patients In Lung Ward at Dr. M.Djamil Padang Hospital Irawan, Eka; Medison, Irvan; Khairsyaf, Oea; Anggraini, Fenty
Jurnal Respirologi Indonesia Vol 42, No 1 (2022)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v42i1.268

Background: Sepsis is a systemic inflammatory response to severe infections, sepsis is a major cause of morbidity and mortality. This study aims to determine the outcome prediction using qSOFA, SpO2/FiO2 Rasio and Procalcitonin in sepsis pneumonia patients in Lung ward of Dr. M DJamil Padang Hospital.Â Methods: Cohort study design with correlative analytics for 43 pneumonia sepsis patiens in Lung ward at Dr. M. Djamil Padang Hospital from September 2019 until to Februari 2020. Samples were taken by consecutive sampling method.Â Results: There were a significant relationship between qSOFA score with procalcitonin (p value = 0.006). There were no significant relationship between SpO2/FiO2 Rasio with procalcitonin (p value = 0.128). There were a significant relationship between qSOFA scores with patient outcomes (p value = 0.036), there were no significant relationship between procalcitonin with patient outcomes (p value = 0.205), and there were a significant relationship betweenSpO2/FiO2 Rasio with patient outcomes (p value = 0.019).Â Conclusion: qSOFA and SpO2 / FiO2 Rasio can predict the outcomes of patients with sepsis pneumoniaÂ

Hubungan Paparan Asap Rokok Lingkungan dengan Kejadian Dismenorea Primer Rifki YS; Ermawati Ermawati; Irvan Medison
Jurnal Kesehatan Andalas Vol 5, No 3 (2016)
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v5i3.582

AbstrakDismenorea primer lebih sering terjadi dibanding dismenorea sekunder dengan insiden tersering pada remaja dan usia 20-an. Penyebab tersering dismenorea primer adalah karena tingginya prostaglandin yang dapat disebabkan oleh beberapa faktor, salah satunya adalah akibat dari nikotin yang terkandung dalam paparan asap rokok lingkungan. Tujuan penelitian ini adalah menentukan hubungan antara paparan asap rokok lingkungan dengan kejadian dismenorea primer pada mahasiswi pendidikan dokter Fakultas Kedokteran Universitas Andalas. Penelitian ini menggunakan rancangan cross sectional. Sebanyak 95 mahasiswi yang dipilih dengan teknik propotional random sampling. Data dikumpulkan melalui pengisian kuesioner oleh responden yang kemudian dianalisis melalui uji chi-square. Hasil penelitian menunjukkan bahwa distribusi kejadian dismenorea primer pada mahasiswi pendidikan dokter Fakultas Kedokteran Universitas Andalas adalah 71.6%. Mahasiswi yang terpapar asap rokok lingkungan adalah 32.6%. Hasil uji chi-square menunjukkan bahwa paparan asap rokok lingkungan (p=0.020) memiliki hubungan dengan kejadian dismenorea primer. Disimpulkan bahwa sebagian besar mahasiswi mengalami dismenore primer dan sepertiganya terpapar asap rokok lingkungan, serta terdapat hubungan bermakna antara paparan asap rokok lingkungan dengan kejadian dismenorea primer.Kata kunci: dismenorea primer, asap rokok lingkungan, mahasiswi AbstractPrimary dysmenorrhoea is more common than the incidence of the most common secondary dysmenorrhoea in adolescents and 20s. The most common cause of primary dysmenorrhoea is due to the high prostaglandin which can be caused by several factors, one of which is a result of the nicotine contained in cigarette smoke exposure environment. The objective of this study was to determine there relationship between environmental tobacco smoke exposure on the incidence of primary dysmenorrhoea Student Medical Education Faculty of Medicine, University of Andalas.This study used a cross sectional design. The 95 students were selected by Proportional random sampling technique. Data were collected through questionnaires, then analyzed by Chi-square test .The results showed that the distribution of the incidence of primary dysmenorrhoea in physician education student of the Faculty of Medicine, University of Andalas was 71.6% . While the student is exposed to environmental smoke is 32.6 %. The results of chi-square statistical test showed that environmental tobacco smoke exposure ( p = 0.020 ) had a relationship with the incidence of primary dysmenorrhoea .From the results, it can be concluded that the Student Pre-clinic Medical Education Program Faculty of Medicine, University of Andalas 2013-2014 school year are subjected to one-third of primary dysmenorrhea and environmental exposure to cigarette smoke, and there is a significant relationship between environmental tobacco smoke exposure with the incidence of primary dysmenorrhoea. Keywords: primary dysmenorrhoea, environmental tobacco smoke exposure, students

Hubungan Pelaksanaan Strategi Directly Observed Treatment Short Course dengan Hasil Pengobatan Tuberkulosis Paru Puskesmas Padang Pasir Kota Padang 2011-2013 Nurmadya Nurmadya; Irvan Medison; Hafni Bachtiar
Jurnal Kesehatan Andalas Vol 4, No 1 (2015)
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v4i1.223

AbstrakTuberkulosis (TB) paru masih menjadi masalah utama kesehatan global di dunia. Pada tahun 2011, Indonesia berada di posisi keempat dengan jumlah penderita TB terbanyak di dunia. Dalam upaya penanggulangan TB, Indonesia telah mengadopsi strategi DOTS sejak tahun 1995. Berdasarkan laporan tahunan Dinas Kesehatan Kota Padang tahun 2011, angka keberhasilan pengobatan di Puskesmas Padang Pasir yaitu 71,43% dan angka ini belum mencapai target nasional. Penelitian ini bertujuan untuk mengetahui hubungan pelaksanaan strategi DOTS dengan hasil pengobatan TB paru di Puskesmas Padang Pasir Kota Padang. Jenis Penelitian ini adalah analitik dengan desain cross sectional study. Data dikumpulkan melalui wawancara kepada responden menggunakan kuisioner yang kemudian di analisis melalui uji Chi-Square. Hasil uji statistik Chi-Square menunjukkan adanya hubungan antara pelaksanaan komitmen oleh petugas kesehatan (p-value : 0,000), pelaksanaan pemeriksaan dahak (p-value: 0,005, ketersedian OAT (p-value : 0,002) dengan hasil pengobatan TB paru. Hasil uji statistik pada peranan PMO (p-value : 0,185) dan pencatatan pelaporan penderita TB paru (p-value 0,184) menunjukkan tidak terdapat hubungan dengan hasil pengobatan TB paru.Kata kunci: tuberkulosis paru, DOTS, hasil pengobatanAbstractTuberculosis (TB) remains a major problem pulmonary global health in the world. In 2011, Indonesia was in fourth position with the highest number of TB patients in the world. InTB controlefforts, Indonesia hasadopted theDOTS strategysince 1995.Based on the annual report of Padang City Health Department in 2011, the treatment success rate in Padang Pasir Health Center is 71.43% and this figure has not reached the national target. The study aims to determine the relationship implementation of the DOTS strategy with pulmonary TB treatment success in health centers Padang Padang Pasir.This type of study design was cross-sectional analytic study. Data were collected through interviews with respondents using a questionnaire which was then analyzed by chi-square test. The results of the chi -square statistical tests showed that the implementation of commitments by health workers (p - value: 0.000), the implementation of sputum examination (p - value : 0.005), availability of OAT (p - value : 0.002) have a correlation with the results of treatment of pulmonary tuberculosis . While results statistical tests on the role of the PMO (p - value : 0.185) reporting and recording of pulmonary TB patients (p– value : 0.184) showed there was no correlation with the results of treatment of pulmonary tuberculosis.Keywords: pulmonary tuberculosis, DOTS, treatment success

Gambaran Derajat Merokok Pada Penderita PPOK di Bagian Paru RSUP Dr. M. Djamil Fadhil el Naser; Irvan Medison; Erly Erly
Jurnal Kesehatan Andalas Vol 5, No 2 (2016)
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v5i2.513

AbstrakPenyakit Paru Obstuktif Kronik (PPOK) adalah penyakit dengan karakteristik keterbatasan saluran napas yang tidak sepenuhnya reversibel dan dapat dicegah. Indonesia merupakan salah satu negara berkembang yang memiliki jumlah perokok aktif yang tinggi. Tujuan penelitian ini adalah untuk mengetahui gambaran derajat merokok pada penderita PPOK di Bagian Paru Rumah Sakit Umum Pusat Dr. M. Djamil Padang. Ini adalah penelitian deskriptif retrospektif dengan menggunakan data rekam medik penderita merokok dengan yang dirawat di Bagian Paru Rumah Sakit Umum Pusat Dr. M. Djamil. Data sekunder diambil dari rekam medik penderita Penyakit Paru Obstruktif Kronik (PPOK) yang dirawat di Bagian Paru Rumah Sakit Umum Pusat dari 1 Januari 2013 sampai 31 Desember 2013. Data diolah secara manual dan disajikan dalam bentuk tabel distribusi frekuensi. Sebanyak 20 subjek didapatkan nilai indeks brinkman berat sebanyak 15 orang. Setelah dilakukan uji statistik didapatkan hubungan yang signifikan antara derajat merokok dengan derajat keparahan PPOK (p = 0,033) dan korelasi yang kuat antara keduanya (r = 0,577). Terdapat hubungan yang signifikan dan korelasi yang kuat antara derajat merokok dengan derajat keparahan PPOK.Kata kunci: merokok. indeks Brinkman, PPOK AbstractCOPD is a disease with airway limitation characteristic. That is not fully reversible and can be prevented. Smoking is the leading cause of COPD. Indonesia is one of the developing countries that have a high number of active smokers. The increase in prevalence is also occurred in the province of West Sumatra, which increased from 30.2% in 2007 to 38.4% in 2010. The objective of this study was to describe the degree of smoking in patients with COPD in Pulmonary Section General Hospital Dr. M. Djamil. This study used a retrospective descriptive design using medical record data of smoker patients with Chronic Obstructive Pulmonary Disease (COPD) who were treated in the Pulmonary Section General Hospital Dr. M. Djamil. The data was taken from the secondary status of patients with Chronic Obstructive Pulmonary Disease (COPD) who were treated in Pulmonary Section General Hospital from January 1, 2013 to December 31, 2013 that recorded in the medical record. Data processed manually from the status of COPD patients and were presented in the form of frequency distribution table. From 20 subjects obtained that 15 samples were classified to severe Brinkman index. Statistical tests found a significant relationship between the degree of smoking with COPD severity (p = 0.033) and a strong correlation between the two (r = 0.577). There is a significant relationship and strong correlation between the degree of smoking with COPD severity.Keywords: smoking, Brinkman Index, COPD

Gambaran Kejadian Hemoptisis pada Pasien di Bangsal Paru RSUP Dr. M. Djamil Padang Periode Januari 2011 – Desember 2012 Intan Irfa; Irvan Medison; Detty Iryani
Jurnal Kesehatan Andalas Vol 3, No 3 (2014)
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v3i3.151

AbstrakHemoptisis adalah ekspektorasi darah yang berasal dari saluran pernafasan bagian bawah dengan jumlah minimal hingga masif yang dapat membahayakan jiwa. Etiologi hemoptisis seperti infeksi, neoplasma dan kelainan kardiovaskular berbeda kekerapannya di berbagai negara. Di Indonesia dan negara berkembang lainnya, tuberkulosis paru merupakan penyebab utama hemoptisis. Tujuan penelitian ini adalah untuk mengetahui gambaran kejadian hemoptisis pada pasien di bangsal paru RSUP Dr. M. Djamil Padang periode Januari 2011 – Desember 2012. Metode yang digunakan adalah deskriptif secara retrospektif menggunakan data rekam medis pasien rawat inap dengan hemoptisis di bangsal paru RSUP Dr. M. Djamil Padang periode Januari 2011 – Desember 2012. Hasil penelitian menunjukkan bahwa sejak Januari 2011 – Desember 2012 terdapat 103 kejadian hemoptisis dan prevalensi kejadiannya sebesar 3,6%. Sebagian besar pasien dengan hemoptisis adalah laki-laki (65%) dengan kelompok usia terbanyak yaitu 31 – 40 tahun. Sementara distribusi frekuensi pasien dengan hemoptisis berdasarkan riwayat pendidikan terbanyak yaitu tamat SLTA (32%), berdasarkan pekerjaan adalah ibu rumah tangga (29,1%) dan sebagian besar berdomisili di Kota Padang. Klasifikasi hemoptisis terbanyak adalah hemoptisis sedang (34%) dengan etiologi utama tuberkulosis paru (47,6%). Pada penelitian ini didapat angka kematian pasien sebesar 6,8% dari total kejadian hemoptisis.Kata kunci: hemoptisis, prevalensi, tuberkulosis AbstractHemoptysis is expectoration of blood from the lower respiratory tract that varies in amount of blood from small amount to the massive amount and can become threaten of life. The etiology of hemoptysis such as infection, neoplasm and cardiovascular disorder are vary over the world. In Indonesia and other developed countries, pulmonary tuberculosis is a main etiology of hemoptysis. The purpose of this study is to determine the profile of hemoptysis among patients admitted in Pulmonary Department of Dr. M. Djamil Hospital Padang period January 2011 – December 2012. This research was a descriptive survey based on retrospective study design that reviewed the medical record of hospitalized patients with hemoptysis in Pulmonary Department of Dr. M. Djamil Hospital period January 2011 – December 2012. The result has shown that since January 2011 – December 2012 there were 103 patients with hemoptysis, and the prevalence of hemoptysis is 3.6%. Most of patients with hemoptysis are male (65%) with highest frequency distribution based on age group of patients is 31 – 40 years old. While the highest frequency distribution based on patients’ history of education is high school diploma (32%), based on patients’ profession is housewife (29.1%) and most of patients live in Padang. Moderate hemoptysis (34%) were the highest frequency distribution based on classification of hemoptysis, with pulmonary tuberculosis as the main etiology (47.6%). Mortality rate of patients with hemoptysis in this study was 6,8% of all hemoptysis cases.Keywords: hemoptysis, prevalence, tuberculosis

Profil Penderita Penyakit Tuberkulosis Paru BTA Positif yang Ditemukan di BP4 Lubuk Alung periode Januari 2012 – Desember 2012 Eni Yulvia Susilayanti; Irvan Medison; Erkadius Erkadius
Jurnal Kesehatan Andalas Vol 3, No 2 (2014)
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v3i2.69

AbstrakTuberkulosis masih merupakan masalah kesehatan di Indonesia karena prevalensi yang masih tinggi,i terutama di negara berkembang. Karena penyebarannya yang tinggi, maka perlu diketahui bagaimana profil penderita penyakit ini agar penularannya bisa diminimalkan. Tujuan dari penelitian ini adalah untuk mengetahui profil penderita tuberculosis paru BTA positif yang berobat di Balai Pengobatan Penyakit Paru (BP4) Lubuk Alung periode 1 Januari 2012 – 31 Desember 2012. Penelitian ini bersifat deskriptif retrospektif. Instrumen yang digunakan adalah data dari rekam medik di Balai Pengobatan Penyakit Paru (BP4) Lubuk Alung sejak 1 Januari 2012 – 31 Desember 2012. Populasi yang ada seluruhnya dijadikan subjek penelitian. Kemudian dilakukan pencatatan dari beberapa variabel yang diteliti. Hasil penelitian ini menunjukkan bahwa dalam periode tersebut jumlah penderita yang berobat ke BP4 Lubuk Alung adalah 19.440 orang, sebanyak 3.224 orang diantaranya suspek. Penderita BTA (+) 1.109 orang. Jenis kelamin laki-laki (70,8%) lebih banyak dari perempuan. Usia terbanyak adalah 21-30 tahun (23,2%). Daerah asal terbanyak adalah Kab. Padang Pariaman (29,4%). Derajat kepositifan BTA sputum terbanyak berupa positif tiga (+3) adalah (44,2%). Tipe penderita terbanyak merupakan penderita kasus baru sebanyak (91,7%). Keluhan terbanyak yang dirasakan ketika berobat adalah batuk (99%). Sebanyak (13,4%) memiliki penyakit penyerta selain tuberkulosis. Riwayat penggunaan obat sebelumnya sebanyak (11,3%). Sebanyak (99%) dirujuk ke puskesmas dan unit pelayanan kesehatan terdekat. Berdasarkan pendataan profil penderita TB Paru BTA Positif bisa dilihat paling banyak adalah derajat (+3) dan dirujuk ke unit pelayanan terdekat.Kata kunci: profil, tuberkulosis paruAbstractTuberculosis is still a health problem in Indonesia because the prevalence is still high, especially in developing countries. Due to the speed of spread, it is necessary to know the profile of people who suffer from this disease, so the transmission can be minimized. The purpose of this study was to determine the profile of positive acid-fast-bacilli (BTA) in pulmonary tuberculosis patients who seek treatment at Medical Center for Pulmonary Diseases (BP4) Lubuk Alung during the period 1 January 2012-31 December 2012.This is a descriptive retrospective study by taking the data from medical records in BP4 Lubuk Alung. Using the enterety of the population. The results of this study indicate that in this period the number of people who went to BP4 Lubuk Alung were 19.440 people, 3.224 of them suspected tuberculosis. Patients with BTA (+) was 1.109 people. We found male 70.78%. Most are 21-30 years of age 23.2%. The area of origin mostly from Kab. Padang Pariaman 29.4%. The degree of sputum smear positivity mostly positive three (+3) was 44.2%. Type of most patients are people with new cases 91.7%. Most complaints was cough 99%. A total of 13.44% had concomitant diseases other than tuberculosis. History of previous anti tuberculosis drugs (OAT) we found in 11.3%. And 99% are referred to hospitals and health care units nearby. Based on the data collection, profile of positif pulmonary TB patients is (+3) and mostly referred to the nearest health center and service unit.Keywords:profile, pulmonary tuberculosis

Hubungan Tingkat Pengetahuan Mengenai Asma dengan Tingkat Kontrol Asma Katerine Katerine; Irvan Medison; Erlina Rustam
Jurnal Kesehatan Andalas Vol 3, No 1 (2014)
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v3i1.27

AbstrakKontrol gejala asma yang baik merupakan tujuan pengobatan bagi pasien asma. Pengobatan medikamentosa dan self management dibutuhkan untuk mencapai kontrol asma. Pengobatan medikamentosa dan self management yang baik akan tercapai jika pasien asma memiliki pengetahuan mengenai asma . Tujuan penelitian ini adalah untuk mengetahui hubungan antara tingkat pengetahuan asma dengan tingkat kontrol asma. Penelitian ini adalah penelitian cross sectional yang dilaksanakan pada bulan April hingga September 2013 di RSUP Dr. M.Djamil Padang dan RSUD Dr. Achmad Mochtar Bukittinggi. Subjek penelitian yang telah memenuhi kriteria inklusi akan diwawancara menggunakan lembar kuesioner data dasar, kuesioner AGKQ dan kuesioner ACT. Penelitian ini dilakukan pada 65 orang pasien asma yang datang ke Poliklinik Asma di RSUP Dr.M.Djamil Padang and RSUD Dr.Achmad Mochtar Bukittinggi selama bulan April hingga September 2013. Analisis statistik yang digunakan adalah uji chi square dan pengolahan data menggunakan software SPSS 15. Hasil penelitian menunjukkan dari 65 subjek penelitian, 19 (29,2%) orang dengan asma tidak terkontrol memiliki pengetahuan yang rendah, 1 (1,5%) orang dengan asma terkontrol sebagian dengan tingkat pengetahuan yang rendah dan 1 (1,5%) orang pasien asma terkontrol total memiliki pengetahuan asma yang rendah. Pasien dengan pengetahuan asma rendah didapatkan 21 (32,3%) orang dan pengetahuan asma tinggi 44 (67,7%) orang. Berdasarkan uji chi square, terdapat hubungan yang bermakna antara tingkat pengetahuan asma dengan tingkat kontrol asma dengan nilai p = < 0,01 (p < 0,05).Kata kunci: Asthma Control Test (ACT), Asthma General Knowledge Questionnaire (AGKQ), kontrol asma, pengetahuan asma.AbstractGood control of asthma symptomps is a goal for asthmatic patient. Medical treatment and self-management are needed to reach control of asthma. Good medical treatment and a good self-management will be achieved if the asthma patient have knowledge of asthma. The aim of this study is to find relation between asthma knowledge and asthma control. This study is a cross sectional that was conducted in April – September 2013 at asthma clinic Dr.M.Djamil Hospital, Padang and Dr.Achmad Mochtar Hospital, Bukittinggi. Subject who fulfilled the inclusion criteria was interviewed by using basic data information, asthma general knowledge questionnaire (AGKQ) and asthma control test (ACT). Used 65 asthmatic patients as sample that come to Ashma Polyclinic in RSUP Dr.M.Djamil Padang and RSUD Dr.Achmad Mochtar Bukittinggi during April until September 2013. The statistical analysis used chi square test and SPSS 15 for data processing. The results showed that from 65 subjects, 19 (29,2%) subjects with uncontrolled asthma showed low level of asthma knowledge, 1 (1,5%) subjects with partially controlled asthma showed low level of asthma knowledge, and 1 (1,5%) subjects with controlled asthma showed low level of asthma knowledge. Patients with low level of asthma general knowledge was 21 samples (32,3%) and high level of asthma general knowledge was 44 samples (67,7%). Based on chi square test, there is significant association between asthma general knowledge with asthma control p < 0.01 (<0.05).Keywords: asthma control test(ACT), asthma general knowledge questionnaire(AGKQ), asthma control, asthma knowledge

Gambaran Jumlah Eosinofil Darah Tepi Penderita Asma Bronkial di Bangsal Paru RSUP Dr. M. Djamil Padang Demas Nico M Manurung; Ellyza Nasrul; Irvan Medison
Jurnal Kesehatan Andalas Vol 2, No 3 (2013)
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v2i3.143

AbstrakAsma merupakan penyakit gangguan inflamasi kronis saluran pernapasan dengan banyak sel serta elemen seluler yang berperan. Asma dihubungkan dengan hiperresponsif bronkus, keterbatasan aliran udara dan gejala pernapasan yang bersifat reversibel. Salah satu sel yang diketahui berperan besar dalam patogenesis asma adalah eosinofil. Eosinofil melepaskan berbagai mediator seperti Major Basic Protein, Eosinophil Cationic Protein, peroksidase eosinofil, leukotrien C4, serta Platelet-Activating Faktor yang akan merusak epitel saluran napas serta menyebabkan peradangan. Penelitian ini dilaksanakan pada bulan Januari sampai Desember 2012 di Bagian Rekam Medik RSUP Dr. M. Djamil Padang dengan tujuan untuk melihat gambaran jumlah eosinofil darah tepi pada penderita asma bronkial yang dirawat inap. Penelitian yang dilakukan bersifat deskriptif dengan tinjauan retrospektif. Penelitian dilakukan dengan melihat data rekam medis penderita asma bronkial yang dirawat inap di Bangsal Paru RSUP Dr. M. Djamil Padang periode Januari 2010-Desember 2012. Dalam periode dua tahun tersebut, diperoleh 18 sampel yang digunakan pada penelitian ini. Hasil yang diperoleh ialah 4 penderita memiliki jumlah eosinofil darah tepi normal (40-400/mm3) (22,22%) dan 14 penderita memiliki jumlah eosinofil darah tepi dibawah normal (<40/mm3) (77,78%). Tidak ditemukan penderita asma dengan eosinofilia (>400/mm3). Jumlah eosinofil darah tepi pada penderita asma bronkial lebih banyak dibawah normal.Kata kunci: Asma Bronkial, EosinofilAbstractAsthma is a chronic inflammatory disorder of the airways in which many cells and cellular elements play a role. Asthma is associated with hyperresponsif bronchi, airflow limitation, and respiratory symptomps that are reversible. One of cells which is known to play a major role in asthma pathogenesis is eosinophil. Eosinophil release a variety of mediators such as Major Basic Protein, Eosinophil Cationic Protein, Eosinophil Peroxidase, Leukotriene C4, and Platelet Activating Factor that will damage airway epithelium and cause inflammation. The research was conducted in January 2012 through December 2012 at Medical Records Department of RSUP Dr. M. Djamil Padang aiming to see the overview of peripheral blood eosinophil number in patient with bronchial asthma who are hospitalized. The research conducted is using descriptive retrospective review. The study is done by looking medical record data of bronchial asthma patient hospitalized in pulmonary ward of RSUP Dr. M. Djamil Padang in the period of January 2010-December 2012. In the two year period, there are 18 patients which are used in the study. The results are 4 patients had normal peripheral blood eosinophil number (40-400/mm3)(22,22%), 14 patients had low peripheral blood eosinophil number (<40/mm3)(77,78%). There is no patient with eosinophilia (>400/mm3). Peripheral blood eosinophil number in bronchial asthma patient is mostly low.Keywords: Bronchial Asthma, Eosinophil

Hubungan Keteraturan Penggunaan Kortikosteroid Inhalasi dengan Tingkat Kontrol Asma Pasien Berdasarkan ACT di Poliklinik Paru RSUP Dr. M. Djamil Padang Wulan Prisilla Prisilla; Irvan Medison; Selfi Renita Rusjdi
Jurnal Kesehatan Andalas Vol 5, No 1 (2016)
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v5i1.447

AbstrakAsma merupakan penyakit yang didasari oleh reaksi inflamasi pada saluran napas yang dapat dicegah dengan kortikosteroid inhalasi. Asma sukar disembuhkan, sehingga tujuan penatalaksanaan asma adalah asma terkontrol. Penilaian tingkat kontrol asma dapat dilakukan dengan menggunakan kuesioner Asthma Control Test (ACT) yang bersifat subjektif tetapi validitasnya telah diuji. Tujuan penelitian ini adalah menentukan hubungan keteraturan penggunaan kortikosteroid inhalasi dengan tingkat kontrol asma pasien berdasarkan ACT di Poliklinik Paru RSUP Dr. M. Djamil Padang. Penelitian cross sectional analytic ini telah dilakukan dari September hingga Desember 2013. Populasi adalah pasien berusia ≥14 tahun yang didiagnosis asma oleh dokter. Jumlah subjek penelitian sebanyak 96 orang. Data yang diperoleh diolah dan dianalisis menggunakan uji Kolmogorov-Smirnov. Insiden terbanyak asma berada pada kelompok usia lanjut (60,4%). Sebagian besar pasien tidak teratur menggunakan kortikosteroid inhalasi (63,5%) dan pasien dengan asma tidak terkontrol memiliki proporsi tertinggi (59,4%) . Analisis statistik menunjukkan bahwa terdapat hubungan yang bermakna antara keteraturan penggunaan kortikosteroid inhalasi dengan tingkat kontrol asma pasien berdasarkan ACT di Poliklinik Paru RSUP Dr. M. Djamil (p=0,002).Kata kunci: kortikosteroid inhalasi, ACT, tingkat control asma AbstractAsthma is a disease caused by an inflammatory reaction in the patient airways that can be prevented with inhaled corticosteroids. It is known that there is no cure for asthma, so the goal of asthma management is to obtain controlled asthma. The level of asthma control can be assessed by using Asthma Control Test (ACT) questionnaire, this method is subjective but its validity has been tested. The objective of this study was to determine the association between regularity of inhaled corticosteroids application and patient’s level of asthma control based on ACT in the Lung Clinic of Dr. M. Djamil Padang Hospital. A cross sectional analitic was conducted from September to December 2013. The population is patient aged ≥14 years old who were diagnosed with asthma by a doctor. The number of samples is 96 people. The data were processed and analyzed using the Kolmogorov-Smirnov test. The incidence of asthma was highest in the elderly (60,4%). Most patients do not regularly use inhaled corticosteroids (63.5%) and patients with uncontrolled asthma had the highest proportion (59.4%) in this research. Based on statistic analisys, there was significant association between regularity of inhaled corticosteroids application and patient’s level of asthma control based on ACT in the lung clinic of Dr. M. Djamil Padang Hospital (p=0,002).Keywords: inhaled corticosteroids, ACT, level of asthma control

Gender Disparities in Their Effects on Characteristics and Prognostics of Lung Cancer Patients in Pulmonary Ward of Dr. M Djamil Hospital, Padang Sabrina Ermayanti; Afriani Afriani; Sari Nikmawati; Russilawati Russilawati; Irvan Medison; Suyastri Suyastri
Jurnal Respirologi Indonesia Vol 41, No 4 (2021)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v41i4.216

Background: Lung cancer incidence in female tends to increase in many countries. Various studies have reported the characteristics of lung cancer in female are different from male. The purpose of this study was to determine the effect of gender on characteristics of lung cancer at Dr. M Djamil Hospital, Padang.Methods: A retrospective analytic study of lung cancer patients treated in the Pulmonary Ward of Dr. M. Djamil Hospital Padang from January 1, 2004 to December 31, 2017, with recognized cancer cell types. Data were grouped according to gender.Results: This study found that 451 lung cancer patients, male-dominant 77.8%. Female were younger than male (52.97 ± 12.79 years vs. 57.81 ± 11.23 years; p = 0.00). Most of male (94.5%) were smokers and former smokers, while 93.9% of female were non-smokers (p = 0.00). Most female were having prior history of tuberculosis (TB) (21.2% vs 11.0%; p = 0.008) and also prior history of other organs cancer (10.1% vs 3.4%; p = 0.007) than in male. Squamous cells were highest in males (41.1%), while females had adenocarcinoma (55.0%); with p = 0.008. Advanced stage in female more than male (91.8% vs 82.7%; p = 0.027). The mean life expectancy of female was longer than male, respectively 8.74 ± 1.56 and 7.29 ± 0.64 months; (p = 0.95). Conclusion: There are differences in the epidemiology of lung cancer between male and female in Dr. M. Djamil Hospital Padang in the form of age, cell type and staging. Non-smokers, a previous history of TB and a history of cancer in other organs were more dominant in female.

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