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All Journal Jurnal Elektronik Pendidikan Matematika Tadulako Jurnal Kreatif Tadulako Online Jurnal Online Mahasiswa (JOM) Bidang Keguruan dan Ilmu Pendidikan Medika Tadulako Biomedical Journal of Indonesia Jurnal Kesehatan Manarang Jurnal Kesehatan Jurnal Bidan Cerdas Jurnal Aisyah : Jurnal Ilmu Kesehatan Poltekita: Jurnal Pengabdian Masyarakat

Rafika Rafika

FKIP UNTAD

Author-ID : 354280

Biochemistry, Genetics & Molecular Biology Education Electrical & Electronics Engineering Health Professions Mathematics Medicine & Pharmacology Nursing Public Health Veterinary

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ANALISIS GEN NATURAL RESISTENCE ASSOCIATED MACROPHAGE PROTEIN (NRAMP-1) LOKUS D543N PADA PENDERITA DEMAM TIFOID Rafika, Rafika
Medika Tadulako: Jurnal Ilmiah Kedokteran Fakultas Kedokteran dan Ilmu Kesehatan Vol 5, No 2 (2018)
Publisher : Medika Tadulako: Jurnal Ilmiah Kedokteran Fakultas Kedokteran dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar

ABSTRAK Latar Belakang: Gen NRAMP-1 berperan dalam memodulasi respon imun terhadap serangan kuman patogen. Keberadaan gen NRAMP-1 lokus D543N ini mempunyai pengaruh dalam mekanisme pertahanan tubuh terhadap penyakit demam tifoid. Tujuan: Untuk mengetahui polimorfisme gen NRAMP-1 pada penderita demam tifoid dan orang normal. Metode: Jenis penelitian eksperimen yang dilakukan di Laboratorium Biologi molekuler FK UNHAS. Sampel darah kasus berjumlah 25 sampel dan kontrol 25 sampel. Semua sampel darah dilakukan ekstrasi DNA metode Boom dan dilanjutkan amplifikasi gen NRAMP-1 lokus D543N dengan PCR dan hasilnya dilakukan pemotongan DNA dengan RFLP mengunakan Enzim restriksi Ava II (ATCC 27892). Hasil: Hasil pemeriksaan PCR-RFLP diperoleh 6 (24%) sampel kasus tidak terpotong pita DNA ukuran 244 bp berarti mengalami mutasi gen NRAMP-1. Sedangkan 19 (76%) sampel kasus dan 25 (100%) sampel kontrol terpotong terbentuk dua pita DNA ukuran 156 bp dan 88 bp berarti memiliki polimorfisme gen NRAMP-1 normal. Kesimpulan: Terdapat perbedaan polimorfisme gen NRAMP-1 lokus D543N pada penderita demam tifoid dan orang normal. Kata Kunci: Gen NRAMP-1, PCR-RFLP, demam tifoid

CORRELATION BETWEEN SERUM FERRITIN LEVELS AND NUTRITIONAL STATUS OF THALASSEMIA-BETTA MAJOR PATIENTS Rafika, Rafika; Marwoto, Djoko; Hayati, Lusia
Biomedical Journal of Indonesia Vol 5, No 2 (2019)
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v5i2.7986

Thalassemia is a chronic disease that requires repeated blood transfusions, due to impaired hemoglobin synthesis due to mutations of one or more globin genes. Continuous transfusion can cause iron accumulation in the body, especially the heart, liver and endocrine organs, and can cause stunted growth and malnutrition or poor nutrition. This study aims to determine the correlation between serum ferritin levels and the nutritional status of thalassemia-betta major patients in RSUP Dr. Moh. Hoesin Palembang. This research is an observational analytic study with cross sectional design. The sample of this study was thalassemia-betta major patient who was hospitalized in the Department of Pediatrics. Mohammad Hoesin from October to November 2016 who met the participation criteria. Of the 43 patients, the majority (60.5%) had lean bodies according to their weight index according to age (BW / U) and were short stature according to their height index according to age (TB / U), but only 14.0% of patients had undernourished nutrition BB / TB index. Obtained average values of serum ferritin 2837.69 g / L, with a range of 278.7-13867 g / L. The results of the correlation test between serum ferritin levels and nutritional status indicate p = 0.326 and r = 0.153. There was no significant correlation between serum ferritin levels and the nutritional status of thalassemia-betta major patients.

Edukasi Cuci Tangan dan Pemeriksaan Telur Cacing Pada Kuku Tangan Siswa SD Inpres Pampang 1 Makassar Rafika, Rafika; Alang, Hasria; Hartini, Hartini
Poltekita: Jurnal Pengabdian Masyarakat Vol. 1 No. 1 (2020)
Publisher : Pusat Penelitian & Pengabdian Masyarakat Poltekkes Kemenkes Palu

Intestinal worm disease is one of the parasitic diseases that still infect humans, especially children. School-age children, especially elementary school children, are generally less familiar with self-sanitation. Most diseases of the worms are transmitted through dirty hands. Community service at SD Inpres Pampang 1 was done to educate students about the implementation of good self-sanitation and precisely how to wash hands based on WHO standards. The tools used in this study were chalkboard, camera, microscope, reaction tube, glass object, glass cover, container/basin, stirrer rod, glass beaker, tube rack, petri dish, nail clippers, and pens. The materials used in this training were hand nails students SD Inpres Pampang 1, water, and salt. Based on the results and evaluation, it concludes 1) Worm infections can occur when there are worm eggs attached to the nails that are swallowed in with food. 2) improving participants ' understanding and knowledge of self-sanitation for everyday life, especially the right-hand washing way.

Teknik Mekanika Tubuh Mengurangi Tingkat Nyeri Punggung Bawah pada Ibu Hamil Trimester III: Body Mechanics Techniques to Reduce Lower Back Pain among Third Trimester of Pregnant Women Rahayu, Nur Azizah Putri; Rafika, Rafika; Suryani, Lili; Hadriani, Hadriani
Jurnal Bidan Cerdas Vol. 2 No. 3 (2020)
Publisher : Poltekkes Kemenkes Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33860/jbc.v2i3.89

In order to reduce and prevent back pain complaints and to form safe and comfortable daily activities during pregnancy, pregnant women need proper body mechanics. The purpose of this research is to know the influence of the application of mechanical body mechanics with lower back pain of the III trimester of pregnant women. This type of research is pre-experimental with one group Pretest posttest design. This research was conducted in the working area of Puskesmas Sangurara. The population in this study is all III-trimester pregnant mothers with a sample number of 31 people, taken with a consecutive sampling technique. The treatment given is the technique of body mechanics observed during 1 week. Data collection using an observation sheet. The results showed before performing mechanical body mechanics there were 71% of respondents experienced moderate pain and after conducting mechanical body mechanics there were 74.2% of respondents experienced mild pain. Based on the Wilcoxon test obtained a p-value <0.001, with an average decrease in pain, is 7.50. The conclusion is the application of body mechanics techniques significantly affect the lower back pain of the III trimester of pregnant women.

Environmental Exposure to Breast Cancer: Study Narrative Review, How to Prevent in Indonesia? Fikri, Elanda; Firmansyah, Yura Witsqa; Ramadhansyah, Muhammad Fadli; Widyantoro, Wahyu; Pratama, Aziz Yulianto; Widyawati, Ayu; Rachmawati, Ike; Muslyana, Muslyana; Sukaningtyas, Ramadani; Hendrawan, Danang; Ilma, Khaira; Nurany, Hanung; Lewinsca, Maurend Yayank; Rafika, Rafika; Laliyanto, Laliyanto
Jurnal Aisyah : Jurnal Ilmu Kesehatan Vol 6, No 3: September 2021
Publisher : Universitas Aisyah Pringsewu

The environment is one of the factors in the epidemiological triad as the concept of the emergence of a disease, including breast cancer which is the global burden. Globally, WHO declared breast cancer to have 2.26 million new cases per year in 2020, with the mortality rate climbing to 685,000. In Indonesia, breast cancer has the highest incidence rate for women, with 1.4 per 1000 population in 2013 growing to 1.79 per 1000 people in 2018. This review aims to describe environmental exposure factors that have the potential to cause breast cancer. The review study used the narrative review method with a screening process of 28 articles used. Environmental exposures that become potential occurrences of breast cancer are divided into 4, exposure to pesticides, exposure to household chemicals, exposure to food packaging, and exposure to air pollution which have different pathophysiologies for each exposure. Exposure to chemicals such as DDE and DDT in pesticides that have been proven to be carcinogenic and are still used in Indonesia. Exposure to chemicals from household chemicals such as PCBs, Benzophenone, and Phthalates in some household appliances are also carcinogenic substances. The use of BPA, BaP, and 2-Amino-1-Methyl-6-Phenylimidazo [4,5-B] pyridine in food packaging trigger breast cancer. Exposure to cigarette smoke or smoking behavior, consumption and evaporation of alcohol, as well as exposure to PM2.5 are air pollutants that are at risk of causing breast cancer. How to prevent it, we can use biopesticide, bioplastic, change a healthy lifestyle and replace fossil fuels into biofuels. Abstrak: Lingkungan merupakan salah satu faktor dalam triad epidemiologi sebagai konsep munculnya suatu penyakit, termasuk kanker payudara yang menjadi beban global. Secara global, WHO menyatakan kanker payudara memiliki 2,26 juta kasus baru per tahun pada tahun 2020, dengan angka kematian meningkat menjadi 685.000. Di Indonesia, kanker payudara memiliki angka kejadian tertinggi pada wanita, dengan 1,4 per 1000 penduduk pada tahun 2013 tumbuh menjadi 1,79 per 1000 orang pada tahun 2018. Tinjauan ini bertujuan untuk mendeskripsikan faktor paparan lingkungan yang berpotensi menyebabkan kanker payudara. Kajian review menggunakan metode narrative review dengan proses screening sebanyak 28 artikel yang digunakan. Paparan lingkungan yang menjadi potensi terjadinya kanker payudara dibagi menjadi 4, paparan pestisida, paparan bahan kimia rumah tangga, paparan kemasan makanan, dan paparan polusi udara yang memiliki patofisiologi yang berbeda untuk setiap paparan. Paparan bahan kimia seperti DDE dan DDT pada pestisida yang telah terbukti bersifat karsinogenik dan masih digunakan di Indonesia. Paparan bahan kimia dari bahan kimia rumah tangga seperti PCB, Benzophenone, dan Phthalates di beberapa peralatan rumah tangga juga merupakan zat karsinogenik. Penggunaan BPA, BaP, dan 2-Amino-1-Methyl-6-Phenylimidazo[4,5-B]pyridine dalam kemasan makanan memicu terjadinya kanker payudara. Paparan asap rokok atau perilaku merokok, konsumsi dan penguapan alkohol, serta paparan PM2.5 merupakan polutan udara yang berisiko menyebabkan kanker payudara. Cara mencegahnya, kita bisa menggunakan biopestisida, bioplastik, mengubah gaya hidup sehat dan mengganti bahan bakar fosil menjadi biofuel.

Experimental Studies at Company X: Provision of Media Posters and K3 Inspections on Knowledge of Worker Safety in the Warping Section Rafika, Rafika; Lestantyo, Daru; Suroto, Suroto
Jurnal Aisyah : Jurnal Ilmu Kesehatan Vol 6, No 3: September 2021
Publisher : Universitas Aisyah Pringsewu

The purpose of this study was to analyze the effect of giving poster media and K3 inspection on the safety knowledge of workers in the warping section at PT X. This study used a quasi-experimental type of research. This research was conducted at a convection industry company, namely PT X which is prone to work accidents from the results of a survey conducted by researchers. There are 62 employees in the warping division, namely 18 women and 44 men. Respondents in this study had a minimum age of 21 years and a maximum of 51 years with an average age of 33,32258 years. The majority of respondents have a high school education, which is 52 people (83.9%). Then there are 8 people with junior high school education (12.9%), and 2 people with S1 (3.2%), with a total of 62 people (100%). The average respondent worked for 8,2903 years, the minimum respondent worked 1 year and a maximum of 19 years. This means that 62 respondents have standard work experience of 8 - 9 years. Results of this study indicate that the provision of a Media Poster has an effect on Occupational Safety Knowledge. There is a positive influence between the Provision of Media Posters on Occupational Safety Knowledge. K3 Inspection of Occupational Safety Knowledge. K3 inspection has a positive effect on Occupational Safety Knowledge. Meanwhile, education, age and years of service as confounding variables have no effect on employee safety knowledge.Penelitianini bertujuan untuk mengetahuipengaruh pemberian media poster dan inspeksi K3 terhadap pengetahuan keselamatan kerja pada pekerja di bagian warping di PT X. Jenis dari penelitian ini adalah kuasi eksperimental. Penelitian ini dilakukan pada perusahaan industry konveksi yaitu PT X yang mana rentan terjadi kecelakaan kerja dari hasil survey yang dilakukan peneliti. Karyawan bagian warping adalah 62 orang yaitu 18 perempuan dan 44 laki-laki. Responden pada penelitian ini memiliki umur minimal 21 tahun dan maksimal 51 tahun dengan rata-rata berumur 33,32258 tahun. Responden mayoritas berpendidikan SMA yaitu berjumlah 52 orang (83,9%). Kemudian mereka yang berpendidikan SMP ada 8 orang (12.9%), dan S1 ada 2 orang (3.2%), dengan total 62 orang (100%). Rata-rata responden bekerja selama 8,2903 tahun, minimal responden bekerja 1 tahun dan maksimal 19 tahun. Hal ini berarti dari 62 responden mereka memiliki pengalaman kerja standar 8 - 9 tahun. Hasil penelitian ini menunjukkan bahwa pemberian Media Poster berpengaruh terhadap Pengetahuan Keselamatan Kerja. Terdapat pengaruh positif antara Pemberian Media Poster terhadap Pengetahuan Keselamatan Kerja. Inspeksi K3 terhadap Pengetahuan Keselamatan Kerja, Inspeksi K3 berpengaruh positif terhadap Pengetahuan Keselamatan Kerja. Sedangkan Pendidikan, usia dan masa kerja sebagai variable perancu tidak memiliki pengaruh terhadap Pengetahuan Keselamatan Kerja karyawan.

Co-Authors Anggraini Anggraini Baharuddin Paloloang Candriasih, Putu Daru Lestantyo Devi Risma Elanda Fikri Elviyaningsih, Susan Febrialismanto, Febrialismanto Hadriani, Hadriani Hadriani, Hadriani HARTINI HARTINI Hasria Alang Hendrawan, Danang Ike Rachmawati Ilma, Khaira Laliyanto, Laliyanto Lewinsca, Maurend Yayank Lili Suryani Lusia Hayati, Lusia Marwoto, Djoko Muliani Muliani, Muliani Muslyana, Muslyana Nurany, Hanung Pratama, Aziz Yulianto Rahayu, Nur Azizah Putri Ramadhansyah, Muhammad Fadli Sri Restu Tempali Sukaningtyas, Ramadani Suroto Suroto Tondong, Henrietta Imelda Wahyu Widyantoro Widyawati, Ayu Yura Witsqa Firmansyah

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