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All Journal JURNAL FARMASIMED (JFM) JURNAL PENELITIAN FARMASI & HERBAL Jurnal Pengmas Kestra (JPK)
Asti Pratiwi
Institut Kesehatan Medistra Lubuk Pakam
Health Professions Medicine & Pharmacology Nursing Public Health

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Journal : JURNAL FARMASIMED (JFM)

 1 
PENETAPAN KADAR VITAMIN C PADA KULIT PISANG (Musa paradisiaca) DENGAN METODE SPEKTROFOTOMETRI UV-VISIBLE TAHUN 2018 Asti Pratiwi; Ardita Febrianty Manurung; Jhoti sumitra
Jurnal FARMASIMED (JFM) Vol 2 No 2 (2020): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v2i2.363

Abstract

Background: Vitamin C is a vitamin that is water soluble qnd one vitamin that are needed by the body. To meet the intake of vitamin C needed source of vitamin a derived from fruits, one of which is banana. Part of the banana , which is still rarely used is its skin. Banana peel is very beneficial for health however the situation is only considered as waste that has not been utilized well. This study aims to determine the levels of vitamin C on the skin of the banana (Musa paradisiaca) by the method of spectrofotometry uv-visible wavelength 224,5 nm. Method: This research use experimental with purely research stage comprise sample preparation, qualitative test, making the solution of the parent raw, quantitative test, determination of wavelength of maximum vitamin and creation of calibration surve. Result: Based on the research that has been done obtained the result of the qualitative test to prove the presence of high content of vitamin C contained in banana peels, with the highest level obtained in the skin of the plantain by 0,0253 mg/ml and the levels of the lowest on a banana peel the wax by 0,0172 ng/ml. Discussion: Levels of vitamin C on the skin of the banana barangan of 0, 0219 mg/ml, sample a banana skin banten by 0, 0173 mg/ml, sample a banana peel wax by 0, 0172 mg/ml and sample the skin of plantain by 0, 0253 mg/ml.
EFEKTIVITAS FORMULASI SEDIAAN LOTION DARI EKSTRAK ETANOL DAUN ALPUKAT (PERSEA AMERICANA MILL) SEBAGAI PELEMBAB KULIT Hastrina Novasari; Asti Pratiwi; Nopri Mahmiara
Jurnal FARMASIMED (JFM) Vol 3 No 2 (2021): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v3i2.571

Abstract

Avocado plant can be formulated into a lotion because preparation based on previous research avocado leavescontain high antioxidant is represented with flavonoid compound. The purpose of this study is to know avocado leaves can be formulated into the preparation of lotion and to know the preparation of lotion from extract etanol avocado leavescan moisturaize the skin. The research uses exsperimental method. Avocado leaves is exstrach by maceration process. Exanination of lotion preparation by this research is phytochemical screening test, pH test,irritation test and skin moisturaise test with concentration 3% and 5%. Extrach ethanol avocado leaves can be formulated into a skin moisturaizing lotion preparation with irritation test results showed no irritation on the skin, skin moisture examination result concentration 5% moist. The result showed that moisturaizing lotion preparation from avocado leaves ethanol extrach (Persea americana Mill) for skin moisture with different concentration can be formulated into skin moisturaizing lotion preparation
FORMULASI EKSTRAK DAUN PANDAN WANGI (Pandanus amaryllifolius Roxb) SEBAGAI MASKER GEL PEEL OFF Dewi Kartika; Lulu Atikah; Asti Pratiwi
Jurnal FARMASIMED (JFM) Vol 4 No 1 (2021): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v4i1.801

Abstract

Pandan wangi (Pandanus amaryllifolius Roxb) adalah tanaman yang mengandung alkaloid kimia, flavonoid, tanin, dan polifenol. Penelitian ini bertujuan untuk mengetahui apakah daun pandan wangi dapat diformulasikan sebagai masker gel peel of untuk melembabkan kulit. Ekstrak daun pandan wangi dibuat dalam konsentrasi 0% (blanko), 2,5%, dan 5% yang dibuat dalam sediaan 30 gram. Uji yang dilakukanmeliputi organoleptik, homogenitas, pH, persiapan waktu kering, dan kelembapan. Hasil penelitian menunjukkan bahwa ekstrak daun pandan wangi dapat dibuat sebagai bentuk masker gel dan memenuhi evaluasi fisik bentuk. Hasil tes homogenitas menunjukkan sediaan homogen, pH dalam kisaran 6.0 yang relatif aman pada permukaan kulit wajah. Waktu persiapan mengering selama 30 menit dan memenuhi persyaratan waktu pengeringan. Kemampuan untuk melembabkan kulit lebih besar dengan meningkatkan konsentrasi ekstrak yang ditambahkan. Kemampuan rata-rata tertinggi untuk melembabkan kulit adalah 39,0%. dalam tes kelembaban konsentrasinya adalah 5% ekstrak daun harum pandan karena kulit masker gel pelembab alami sangat baik. Kesimpulannya menunjukkan bahwa ekstrak daun pandan wangi dapat diformulasikan menjadi masker gel peel off yang memiliki kemampuan melembabkan kulit.
ANTI-BACTERIAL ACTIVITY TEST OF SURGERY RHIZOME (CURCUMA DOMESTICA VAL) AGAINST BACTERIA STREPTOCOCCUS MUTANS Asti Pratiwi; Zulfan Hardiansyah Ritonga
Jurnal FARMASIMED (JFM) Vol 4 No 2 (2022): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v4i2.1008

Abstract

Abstract Turmeric (Curcuma domestica Val) contains various compounds such as alkaloids, flavonoids, curcumin, essential oils, saponins, tannins and terpenoids. The curcuminoids in turmeric rhizome are a group of phenolic compounds. Curcumin damages the cytoplasmic membrane and denatures cell proteins which causes the leakage of nutrients from the cells thereby inhibiting the growth of bacteria. The purpose of this study was to test the antibacterial activity of turmeric (Curcuma domestica Val) rhizome against Streptococcus mutans bacteria. In this study, its activity against Streptococcus mutans was seen through laboratory examination using the paper disc method. From the results of the four turmeric rhizome extracts, the average inhibition zone obtained a concentration of 10% produced an average of 14.48 mm. Concentration of 20% produces an average of 16.35 mm. concentration of 30% produces an average of 17.26 mm. Concentration of 40% produces an average of 19.47 mm. In this case, turmeric rhizome extract has strong activity against Streptococcus mutans bacteria. Turmeric rhizome contains secondary metabolites of flavonoids, alkaloids, and tannins. Which works as an antibacterial are flavonoids. Because flavonoids can inhibit nucleic acid synthesis, inhibit cell membrane function and inhibit energy metabolism.
ANTIBACTERIAL ACTIVITY TEST OF CELERY LEAF ETHANOL EXTRACT (APIUM GRAVEOLENS L.) AGAINST BACTERIA STREPTOCOCCUS SANGUINIS Chandra Pranata; Renty Monica; Asti Pratiwi; Yosi Darmirani
Jurnal FARMASIMED (JFM) Vol 6 No 1 (2023): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Kesehatan mulut, gigi penting bagi manusia. Bakteri penyebab terjadinya gingivitis adalah Streptococcus sanguinis. chlorhexidine sebagai larutan yang dimanfaatkan guna membersihkan rongga mulut serta mencegah terjadinya pembentukan plak pada gigi. Alternatif obat kumur yang berasal dari alam adalah daun seledri (Apium graveolens L.) dengan kandungan metabolit sekunder yaitu flavonoid, saponin, alkaloid, tanin. Guna mengetahui kegiatan dan konsentrasi efektif hambatan di ekstrak penelitian ini menggunakan difusi cakram sebagai metodenya dengan konsentrasi ekstrak 12,5%, 25%, 50%, 100% ditandai terbentuknya zona hambat (bening) dengan terbentuknya zona hambat (bening) dengan kontrol positif chlorhexidine dan kontrol negatif aquadest. Hasil uji aktivitas antibakteri ekstrak etanol daun seledri pada bakteri Streptococcus sanguinis adalah pada kelompok kontrol negatif (aquadest) adalah 0 mm, konsentrasi 12,5% adalah 8,15 mm, pada konsentrasi 25% sebesar 7,95 mm, konsentrasi 50% sebesar 9,05 mm, konsentrasi 100% sebesar 9,9 mm, sedangkan pada chlorhexidine (kontrol positif) didapatkan rata-rata sebesar 17,83 mm. Adanya aktivitas ekstrak etanol daun seledri terhadap pertumbuhan bakteri Streptococcus sanguinis dengan konsentrasi yang efektif menghambat pertumbuhan bakteri Streptococcus sanguinis ialah konsentrasi 100%.
Co-Authors Ardita Febrianty Manurung Chandra Pranata Cucu Arum Dwi Cahya Debi Dinha Octora Sitepu Dewi Kartika Fahma Shufyani Jhoti sumitra Krismawati Waruwu Lulu Atikah Nopri Mahmiara Novasari, Hastrina Renty Monica Safrika Juliana Siahaan Wantrio Pardomuan Siringoringo Yanna Rotua Sihombing Yosi Darmirani Zulfan Hardiansyah Ritonga