Indriyati Hadi Sulistyaningrum
Bagian Farmasi Klinik Dan Komunitas Program Studi Farmasi Universitas Islam Sultan Agung

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Journal : Jurnal Farmasi Sains dan Praktis

PENGARUH KONSENTRASI AMILUM UBI JALAR PUTIH (Ipomoea batatas L) SEBAGAI BAHAN PENGIKAT SECARA GRANULASI BASAH TERHADAP SIFAT FISIK GRANUL DAN TABLET SERTA PROFIL DISOLUSI TABLET PARACETAMOL Indriyati Hadi Sulistyaningrum; Arifin Santoso; Abdur Rosyd; Anis Rosita
Jurnal Farmasi Sains dan Praktis Vol 4 No 1 (2018)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/pharmacy.v4i1.2584

Abstract

Hampir 90% bahan baku obat, baik zat aktif maupun bahan tambahan (eksipien) di Indonesia didapatkan melalui impor dari luar negeri, padahal sumber daya Indonesia dapat dikembangkan. Penelitian ini bertujuan untuk mengetahui pengaruh penggunaan bahan pengikat amilum ubi jalar (Ipomoea batatasL) dalam berbagai konsentrasi terhadap sifat fisik granul, tablet dan profil disolusi tablet paracetamol. Pada penelitian ini menggunakan penelitian eksperimental dengan design posttest only control group yaitu menggunakan lima formula amilum ubi jalar putih dan tablet paracetamol merk dagang sebagai kontrol positif. Formula yang digunakan yaitu konsentrasi 5%, 10%, 15%, 20%, dan 25%. Kemudian dilakukan uji granulasi, keseragaman bobot, kekerasan, kerapuhan, disintegrasi dan disolusi. Hasil penelitian menunjukkan bahwa tablet paracetamol dengan bahan pengikat amilum ubi jalar putih yang dibuat memenuhi persyaratan fisik sesuai standar Farmakope Indonesia. Tablet paracetamol yang dihasilkan berwarna putih, memenuhi persyaratan ketika dilakukan pemeriksaan fisik meliputiuji granulasi, keseragaman bobot, kerapuhan, namun pada uji kekerasan didapatkan formula yang memenuhi persyaratan farmakope yaitu pada formula 1 (5%), uji waktu hancur dan disolusi formulasi yang memenuhi syarat adalah formula 1,2,3 (5%,10% dan 15%). Berdasarkan uji analasis Anova dan Kruskal wallis didapatkan terjadinya perbedaan signifikan antar kelompok perlakuan pada uji pengetapan granul, keseragaman bobot, kekerasan, kerapuhan, disintegrasi dan disolusi (p<0,05), kemudian dilanjutkan uji Mann-Whitney dan tidak terjadi perbedaan signifikan antar kelompok pada uji waktu alir dan sudut diam (p>0,05). Kesimpulan dalam penelitian ini adalah konsentrasi amilum ubi jalar putih (Ipomoea batatasL) terhadap sifat fisik granul, tablet dan profil disolusi tablet paracetamol dengan konsentrasi 5% sampai 10%.
COMPARATIVE OF REAL COST AGAINST THE PRICE OF INA-CBG’S BREAST CANCER AND ITS AFFECTING FACTORS IN JKN PROGRAM ERA Arifin Santoso; Indriyati Hadi Sulistyaningrum; Abdur Rosyid; Erwin Budi Cahyono; Ken Wirastuti; Bagus Riyanto
Jurnal Farmasi Sains dan Praktis Vol 6 No 1 (2020)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/pharmacy.v6i1.2963

Abstract

This study aims to determine differences in real cost and INA CBG's rate and to find out the factors that influence the difference between the real cost and INA CBG's rate in patient with breast cancer in JKN Era at Sultan Agung Islamic Hospital between January 2017 and October 2017. This type of research is a non-experimental (observational) study, data taken retrospectively from hospital financial data and medical records of patients. Data analysis using Mann-Whitney is used to determine the suitability of real costs with INA CBG rates. and the Kruskal-Wallis test is used to find out what factors affect real costs. There was difference between the real cost and the INA CBG's rate for class 1 of Rp (-9,861,600), class 2 of Rp (30,643,000), and class 3 of Rp (146,724,100). The factors that influence the real costs were nursing class (p = 0.014) and Length of stay (p = 0.000). The conclusion of this study is that there is a difference between the real cost in patient with breast cancer in JKN Era at Sultan Agung Islamic Hospital between January 2017 and October 2017.
Analysis Of Drug Indicator At The Procurement Stage In The National Health Insurance Era: A study in Advance Health Facility Indriyati Hadi Sulistyaningrum; Arifin Santoso; Sri Intan Lestari; Kusuma Arbianti
Jurnal Farmasi Sains dan Praktis Vol 5 No 2 (2019)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/pharmacy.v5i2.2964

Abstract

Drug procurement is part of an important hospital management to support the availability of the pharmaceutical logistic in hospital to provide good services for the patients. ineffective procurement can result in not achieving the availability of each drug in the amount which are in accordance with the price and budgeting. This research was conducted to obtain an overview of drug management at the procurement stage in Sultan Agung Islamic Hospital (RSIA SA) for the 2017 – 2018 period. Descriptive Observational research methods were used to collect the qualitative and quantitative data. Qualitative data were obtained through interview, and the quantitative data were collected from the document observation provided in Pharmaceutical installation Sultan Agung Islamic Hospital (IFRSISA). The result showed the percentage of the allocation of drug procurement funds in 2017 was 47,6%, and in 2018 it was 37,1%, the frequency of procurement of each drug type was < 76% at 12 times / year, the frequency of delayed payment by the hospital based on the time agreed was 100%. The conclusion of this study shows that the indicator of drug procurement in IFRSISA categorized as good because it is in line with the quality of drug procurement indicators.
PRESCRIPTION COST ANALYSIS IN PATIENTS WITH HYPERTENSION AND TYPE 2 DIABETES MELITUS AFTER THE IMPLEMENTATION OF INDONESIAN NATIONAL HEALTH INSURANCE Indriyati Hadi Sulistyaningrum; Arifin Santoso; Kusuma Arbianti; Garnes Mona Yulieta
Jurnal Farmasi Sains dan Praktis Vol 8 No 3 (September-December 2022)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/pharmacy.v8i3.5956

Abstract

Chronic disease is a long-term health condition that requires on-going medical attention, and is classified as a non-communicable disease. The long-term medical treatment for chronic diseases, such as type 2 diabetes mellitus and hypertension is considerably costly. This study aims to determine the real cost and pattern of drug prescribing as well as the factors affecting the real Prescription Cost for hypertension and type 2 diabetes mellitus after the implementation of Indonesian National Health Insurance (JKN) as seen from the practice of Independent Physicial in collaboration with BPJS Kesehatan (Healthcare and Social Security Agency). This is a non-experimental (observational) study. The data were collected using purposive sampling method with 147 medical prescriptions as the research samples for each type of disease from the patient's medical record. Data were analyzed descriptively to determine Prescription Costs and spearman's rho test was used to determine the factors that influence Prescription Costs. The study revealed that the average Prescription Cost for type 2 DM patients was Rp17,806,- and Rp12,946 for hypertensive patients. Factors that affected Prescription Cost were diagnosis (p= 0.026), type of medicine (p= 0.000) and drug items (p= 0.000). This study concludes that patients with diabetes mellitus were treated with the drug prescription pattern of a combination of metformin and glimepiride, while patients with hypertension were provided with amlodipine. The real Prescription Cost is influenced by several factors, including; the patient's diagnosis, the type of drug given and the number of drug items provided to patients.
PRESCRIPTION COST ANALYSIS IN PATIENTS OF TYPE 2 DM AND HYPERTENSION JOINING CHRONIC DISEASE MANAGEMENT PROGRAM (PROLANIS) AT PUSKESMAS AFTER THE IMPLEMENTATION OF NATIONAL HEALTH INSURANCE Arifin Santoso; Indriyati Hadi Sulistyaningrum; Hesti Dwi Widaryanti; Kusuma Arbianti; Chilmia Nurul Fatiha; Elmiawati Latifah
Jurnal Farmasi Sains dan Praktis Vol 9 No 2 (May-August 2023)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/pharmacy.v9i2.5234

Abstract

To improve the status of public health and carry out social security programs in the health sector, the government started to implement the National Health Insurance. This program covers the participants’ medical care expenses using the capitation system applied in health centers as the First-Level Health Facilities. BPJS Kesehatan has allocated some budget in the form of a capitation rate to first-level health facilities for hypertension and type 2 diabetes mellitus patients after the implementation of National Health Insurance. This research was carried out in 4 health centers, namely Lamper Tengah Health Center, Mangkang Health Center, Mijen Health Center, and Karanganyar Health Center. The data were collected retrospectively from the medical records of 800 patients. The data were analyzed descriptively to determine the prescription cost and Spearman's rho test was used to find the factors that influence the prescription cost. It was revealed that the average prescription cost for type 2 DM patients was IDR 142,293, and for hypertensive patients was IDR 112,735. The prescribing pattern in patients covered by Prolanis program for type 2 DM patients is a combination of glimepiride, metformin with a drug price of IDR 20,670. Factors that have an influence on prescription costs are diagnosis p= 0.033, type of drug (p= 0.000) and drug item (p= 0.000). This study concludes that the factors to influence the drug costs of Prolanis patients at the health centers of Semarang City were the patient's diagnosis, the type of drug given, and the number of drug items given.