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All Journal ELINVO (Electronics, Informatics, and Vocational Education) Jurnal Wiyata : Penelitian Sains dan Kesehatan Jurnal Kesehatan: Jurnal Ilmu- Ilmu Keperawatan, Kebidanan, Farmasi dan Analis Kesehatan Medical Sains : Jurnal Ilmiah Kefarmasian Pharmacy Genius Ad-dawaa: Journal Of Pharmacy Jurnal Pengabdian Masyarakat (Jupemas) Daarul Ilmi: Jurnal Pengabdian Kepada Masyarakat Medical Sains : Jurnal Ilmiah Kefarmasian
Indriastuti, Marlina
STIKes Muhammadiyah Ciamis
Chemistry Computer Science & IT Education Electrical & Electronics Engineering Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Formulation and Evaluation of Moringa Leaves Extract (Moringa oleifera L. ) Lotion with Variation Concentration of Triethanolamin Marlina Indriastuti; Panji Wahlanto; Ditha Septya Utami
Ad-Dawaa : Journal of Pharmacy Vol. 1 No. 1 (2023): Ad-Dawaa: Journal of Pharmacy (May 2023)
Publisher : LPPM STIKes Muhammadiyah Ciamis

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52221/dwj.v1i1.222

Abstract

The Indonesian people know the moringa plant as a plant for consumption as a vegetable, a fetid decoction as well as animal feed. However, the Moringa plant, especially in the leaves, has another benefit , namely as an antioxidant. Antioxidants in Moringa leaves contain tannins, flavonoids, saponins, alkaloids, steroids and terpenoids. The purpose of this study was to determine a good formulation for the preparation of moringa leaf extract lotion with variations in the concentration of triethanolamine. The research method used is the experimental method. Data analysis was performed using the One Way Anova and Kruskal Wallis Test statistical methods . The results showed that the organoleptic test of slightly thick texture preparations for formula I, thick texture for formulas II and III; typical preparation odor of Moringa leaf extract; the color of the preparation is yellow. Homogeneity test of formula I was not homogeneous, formula II was not homogeneous in the third replication, formula III was homogeneous. The average viscosity test for formula I was 1,800 c.Ps, formula II was 8,300 c.Ps, formula III was 1,666 c.Ps. The average pH test for formula I was 6, formula II was 7, formula III was 8. The average adhesion test for formula I was 02.76 seconds, formula II was 02.02 seconds, formula III was 01.37 seconds. The average spreadability test for formula I was 3.9 cm, formula II was 6.6 cm, formula III was 6.9 cm. Based on the evaluation results obtained, it can be concluded that the triethanolamine concentration of 2.5% produces a good formulation for lotion preparations.
Comparison of Antioxidant Power Extract of Ethanol Extract, Hard Shell and Seeds on Melinjo ( Gnetum gnemon L.) with DPPH Method (1,1-diphenyl-2-picrylhydrazyl) Windy Widyawatin; Marlina Indriastuti
Ad-Dawaa : Journal of Pharmacy Vol. 1 No. 1 (2023): Ad-Dawaa: Journal of Pharmacy (May 2023)
Publisher : LPPM STIKes Muhammadiyah Ciamis

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52221/dwj.v1i1.225

Abstract

The human body cannot be avoided from exposure to free radicals in everyday life. Free radicals are very dangerous for the body, one of which causes degenerative diseases. One of the plants that is thought to be able to inhibit free radicals is the melinjo plant. The processing of melinjo plants in the community is only used as a vegetable, so there is a need for research on the benefits of antioxidants in melinjo plants. The purpose of this study was to explore the parts of melinjo which had the best antioxidant activity found in the soft shell, hard shell and seeds of melinjo (Gnetum gnemon L.) with different solvent concentrations. The research method used was to prepare test samples by maceration process using 50% and 70% ethanol, then the extracts were tested for antioxidants using the DPPH method. Data analysis was performed using the ANOVA statistical test with a 98% confidence level. The results showed that the optimal percentage of free radical inhibition was obtained in 50% ethanol solvent, the outer shell of melinjo was 53.29%, and the IC50 was 318.18 ppm. Based on the One way Anova test (p>0.02) there was no difference between the use of 50% and 70% ethanol solvent on the antioxidant activity of the outer shell, hard skin and melinjo seed samples.
Evaluation of Waiting Time Prescription Services in Hospital Pharmacy Installations in the Tasikmalaya Area Nita Asiah; Marlina Indriastuti
Ad-Dawaa : Journal of Pharmacy Vol. 1 No. 2 (2023): Ad-Dawaa: Journal of Pharmacy (November 2023)
Publisher : LPPM STIKes Muhammadiyah Ciamis

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52221/dwj.v1i2.416

Abstract

Pharmaceutical Services in Hospitals are part which is inseparable from the Home health service Hospital System that is oriented towards patient service, provision pharmaceutical preparations, medical devices and consumable medical materials quality and affordable for all levels of society. The aim of this research is to determine the suitability of the waiting timer for recipe service at Medika Citratama Hospital in Tasikmalaya base on Minister of Health Regulation No.129/Menkes/SK/II/2008, namely the waiting time for concoction 60 minutes and non-concoction waiting time 30 minutes. The research method is descriptive by making observations or observing directly using observation. Data taken were 370 outpatient prescriptions, consisting of 270 non-concocted and 90 concocted prescriptions. The average waiting time for prescription services is 26.30 minutes for non-mixed prescriptions and 52.20 minutes for prescriptions. concoction.
Pelatihan Pemanfaatan Sediaan Farmasi Tradisional Berbasis Bahan Alami dengan Kearifan Lokal Sebagai Bekal Gaya Hidup Back to Nature Marlina Indriastuti; Restu Haniel Febrari
Jurnal Pengabdian Masyarakat (Jupemas) Vol 4, No 1 (2023)
Publisher : Universitas Bakti Tunas Husada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36465/jupemas.v4i1.1037

Abstract

A "back to nature lifestyle is currently a trend among people. Back to nature is the use of natural raw materials to be used in various products, such as bedak dingin and scrub. Community service aims to increase public knowledge and understanding of the use of plants as raw materials in products. The methods used are lectures and questions and answers in counseling, while demonstrations and practical work are in training. Materials such as rice, Kaempferia galanga, and turmeric are natural raw materials used in activities. The results of the community service from the outreach activities on the use of traditional medicines by the active participants in the question and answer session indicated that the extension materials were received by the participants. The training activities for bedak dingin of rice, Kaempferia galanga, and turmeric scrub were carried out by the participants and the team. The training ran smoothly, and the participants actively practiced. Products resulting from the training are given to participants. The conclusion from this community service activity is that the participants gave a positive response and showed that their knowledge of medicinal plants increased.ABSTRAKGaya hidup back to nature saat ini menjadi tren dikalangan masyarakat. Back to nature merupakan penggunaan bahan baku alam untuk dimanfaatkan pada berbagai produk, seperti bedak dingin beras kencur dan lulur kunyit. Pengabdian kepada masyarakat bertujuan meningkatkan pengetahuan dan pemahaman masyarakat mengenai pemanfaatan tanaman untuk digunakan sebagai bahan baku dalam produk. Metode yang digunakan adalah ceramah dan tanya jawab dalam penyuluhan sedangkan demonstrasi dan kerja praktek dalam pelatihan. Bahan seperti beras, kencur, dan kunyit merupakan bahan baku alam yang digunakan dalam kegiatan. Hasil pengabdian kepada masyarakat dari kegiatan penyuluhan pemanfaatan obat tradisional  peserta aktif dalam sesi tanya jawab menandakan materi penyuluhan diterima peserta.  Kegiatan pelatihan bedak dingin beras kencur dan lulur kunyit dilakukan oleh peserta dan tim. Pelatihan berjalan lancar dan peserta aktif mempraktekan langsung. Produk yang dihasilkan dari pelatihan, diberikan pada peserta. Kesimpulan dari kegiatan pengabdian kepada masyarakat ini adalah peserta memberikan respon positif, dan menunjukkan pengetahuan mengenai tanaman obat menjadi meningkat.
Penyuluhan Tentang Pemanfaatan Sambiloto (Andrgraphis paniculata) Untuk Mencegah dan Mengobati Penyakit Hipertensi Siti Rahmah Kurnia Ramdan; Marlina Indriastuti; Anna L Yusuf; Davit Nugraha; Panji Wahlanto
Daarul Ilmi: Jurnal Pengabdian Kepada Masyarakat Vol. 2 No. 1 (2024): Daarul Ilmi: Jurnal Pengabdian Kepada Masyarakat (Januari-Juni 2024)
Publisher : LPPM STIKes Muhammadiyah Ciamis

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52221/daipkm.v2i1.564

Abstract

Introduction: Hypertension is one of the factors causing cardiovascular disease and is the main cause of death in the world. Hypertension can be influenced by various factors, including genetic factors and an unhealthy lifestyle. Preventing and treating hypertension is very important in order to reduce risk factors for death. Prevention and treatment of hypertension with traditional medicine or herbal medicine is an alternative that is currently in great demand and attention because it has minimal side effects and is quite effective. Andrographis paniculata is a medicinal plant that has been widely studied and is effective in preventing and treating hypertension. The main content of this plant is andrographolidine which is a phytochemical substance which has many benefits, including antihypertension. Objective: The aim of this outreach activity is to provide understanding to the public about the use of bitter (Androghraphis paniculata) to prevent and treat hypertension. Method: Education to the public about the use of Androghraphis paniculata is carried out through the lecture method. The material presented is an explanation of hypertension, the benefits of bitter as a medicinal plant, the benefits of bitter in preventing and treating hypertension and how to process it on a household scale. Explanation of how to process bitter for treatment, namely using the infusion method. Giving pre-tests and post-tests to counseling participants is carried out to evaluate the level of community understanding. Result: By providing education about the use of bitter to prevent and treat hypertension, it can increase public knowledge about hypertension, the causal factors, as well as the benefits of bitter and how to use it as a medicinal plant. Knowledge before and after counseling increased by 36.65%. The community is very enthusiastic in following the outreach that we do. Conclusion: With the outreach, participants know more about hypertension and the use of bitter in preventing and treating hypertension and how to process it. Participants' knowledge increased by 36.65%.
HUBUNGAN PENGETAHUAN DAN EFEK SAMPING OBAT TERHADAP KEPATUHAN PENGOBATAN PASIEN TUBERKULOSIS DI PUSKESMAS SUKARATU TASIKMALAYA: THE RELATIONSHIP OF KNOWLEDGE AND SIDE EFFECTS OF MEDICINE ON TREATMENT COMPLIANCE IN TUBERCULOSIS PATIENTS IN PUSKESMAS SUKARATU TASIKMALAYA Nia Kurniasih; Nina Muthoharoh; Nurhidayati Harun; Siti Rahmah Kurnia Ramdan; Marlina Indriastuti
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 7 No 2 (2022)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v7i2.301

Abstract

Tuberkulosis merupakan masalah kesehatan masyarakat yang serius di dunia. Pada tahun 2019 sekitar 1,4 juta penduduk dunia meninggal karena Tuberkulosis. Ketidakpatuhan terhadap pengobatan Tuberkulosis merupakan hambatan penting dalam pencegahan dan pengendalian penyakit Tuberkulosis. Kepatuhan yang buruk dapat menyebabkan penyakit menular yang berkepanjangan, resistensi obat, kekambuhan ulang dan kematian. Penelitian ini bertujuan untuk mengetahui hubungan tingkat pengetahuan dan efek samping obat terhadap kepatuhan pengobatan pasien Tuberkulosis di Puskesmas Sukaratu, Tasikmalaya. Metode yang       digunakan adalah survei analitik dengan rancangan cross sectional. Pengambilan data menggunakan kuesioner dengan teknik purposive sampling. Analisis data menggunakan Chi Square. Hasil penelitian menunjukkan  responden yang memiliki tingkat pengetahuan baik sebanyak 23 responden dari total 31 responden (74,2%) dan responden  yang mengalami efek samping obat sebanyak 24 responden dari total 31 responden (77,4 %). Sebagian besar responden memiliki tingkat kepatuhan sedang yaitu sebanyak 22 responden (71,0%). Pada penelitian ini menunjukkan adanya hubungan antara tingkat pengetahuan dengan kepatuhan pengobatan pasien Tuberkulosis dengan nilai p-value sebesar 0,046 < 0,05 dan terdapat hubungan terjadinya efek samping obat dengan kepatuhan pengobatan pasien Tuberkulosis dengan nilai p-value sebesar 0, 010 < 0,05.
AKTIVITAS ANTIBAKTERI AIR PERASAN BUAH PEPAYA (Carica papaya L.) TERHADAP PERTUMBUHAN BAKTERI Staphylococcus aureus: ANTIBACTERIAL ACTIVITIES OF PEPAYA JUICE (Carica papaya L.) ON THE GROWTH OF Staphylococcus aureus BACTERIA Davit Nugraha; Anna L. Yusuf; Veri Nugraha; Panji Wahlanto; Marlina Indriastuti
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 7 No 4 (2022)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v7i4.470

Abstract

Bakteri Staphylococus aureus merupakan bakteri patogen dan dapat menyebabkan infeksi mulai dari infeksi kulit ringan sampai dengan infeksi sistemik. Sebagian besar pada awal mulanya Staphylococus aureus peka terhadap penisilin, namun setelah meluasnya penggunaan penisilin ditemukan 65% sampai 85% Staphylococus aureus menghasilkan beta laktamase sehingga menjadi resisten terhadap penisilin G.  Hal tersebut diatas mendorong pengobatan alternatif yang aman dan tidak menimbulkan resistensi untuk menanggulangi infeksi bakteri Staphylococus aureus.  Perasan buah pepaya sering terdengar penggunaan dimasyarakat untuk pengobatan jerawat secara turun temurun, ini dimungkinkan perasan buah pepaya mempunyai efek anti bakteri Staphylococcus aureus. Penelitian ini bertujuan untuk mengetahui kemampuan daya hambat air perasan buah papaya (Carica Papaya L) terhadap bakteri Staphylococcus aureus. Metode pengujian daya hambat pada air perasan buah papaya menggunakan metode difusi agar dengan konsentrasi 20%, 40%, 60% dan 80%. Air perasan buah pepaya pada penelitian ini mempunyai kemampuan daya hambat yang sedang terhadap pertumbuhan bakteri Staphylococcus aureus, serta konsentrasi yang paling efektif sebesar 60%.
VARIASI FORMULA SEDIAAN FACEMIST EKSTRAK ETANOL DAUN KELOR (Moringa oleifera L.) DAN PENGARUHNYA PADA PENINGKATAN KELEMBABAN WAJAH : FACEMIST ETHANOL EXTRACT OF MORINGA LEAVES (Moringa oleifera L.) FORMULA VARIATIONS AND EFFECTS ON FACIAL MOISTURE IMPROVEMENT Marlina Indriastuti; Nurhidayati Harun; Oktapiana Rismaya; Nia Kurniasih; Anna L Yusuf; David Nugraha
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 8 No 1 (2023)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v8i1.655

Abstract

Facemist adalah produk perawatan kulit wajah berbentuk spray yang diformulasikan untuk membuat kulit lebih segar,  lembab dan dapat digunakan untuk mencegah paparan radikal bebas dari polusi udara. Facemist termasuk salah satu kosmetika yang digunakan untuk merawat dan mempertahankan kondisi kulit wajah. Produk bahan alam untuk perawatan kulit semakin meningkat permintaannya saat ini. Salah satu antioksidan alami terdapat pada daun kelor (Moringa oleifera L.) yang bekerja dengan cara menangkap radikal bebas. Penelitian eksperimental dilakukan dengan memformulasi ekstrak etanol daun kelor menjadi sediaan facemist, uji kelembaban pada kulit wajah baik normal maupun kering dan dilakukan uji cemaran mikrobanya. Variasi formula ekstrak daun kelor yang dibuat 3%, 7%, dan 10%, dari hasil evaluasi sediaan formula terbaik adalah formula D dengan uji cemaran mikroba 2,6 x 102  CFU/ml yang memenuhi standar evaluasi mutu dimana untuk cemaran mikroba tidak boleh lebih dari 103 CFU/ml. Hasil dari penelitian menunjukkan, uji kelembaban facemist pada kulit normal yaitu formula A sebesar 11.76%, B sebesar 12.50%, C sebesar 16.37% dan D sebesar 38.45%. Persen tingkat kelembaban pada kulit kering yaitu formula A sebesar 26.67%, B sebesar 27.00%, C sebesar 28.24% dan D sebesar 30.54%. Maka dapat disimpulkan, formula terbaik adalah formula D dengan hasil uji  kelembaban pada kulit normal 38,45% dan pada kulit kering 30.54% dengan uji cemaran mikroba yang memenuhi persyaratan mutu.
OPTIMASI FORMULA SEDIAAN GRANUL EFFERVESCENT EKSTRAK DAUN KELOR (Moringa oleifera L.): FORMULA OPTIMIZATION OF EFFERVESCENT GRANULE OF MORINGA LEAF EXTRACT (Moringa Oleifera L.) Marlina Indriastuti; Ayu Fuji Astuti; Anna L Yusuf; Faisal Akbar; Rahmah Kurnia R
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 8 No 3 (2023)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v8i3.760

Abstract

Daun tanaman kelor (Moringa oleifera L.) sering dimanfaatkan oleh masyarakat sebagai tanaman obat tradisional yang memiliki kandungan antioksidan. Penelitian yang dilakukan bertujuan untuk mengembangkan formulasi, memperbaiki rasa, dan mengevaluasi granul effervescent ekstrak daun kelor (Moringa oleifera L.) menggunakan perbedaan variasi konsentrasi sorbitol dengan metode granulasi basah. Evaluasi granul effervescent meliputi uji organoleptik, uji kadar air, uji daya alir, uji sudut diam, uji waktu dispersi, uji pH, dan uji ketinggian buih. Tiga formula yang berbeda divariasi dengan memilih konsentrasi sorbitol yang berbeda yaitu formula 1 dengan konsentrasi sorbitol 0,5%, formula 2 1%, dan formula 3 2%. Evaluasi sediaan menunjukkan formula terbaik adalah formula 3 dengan hasil uji evaluasi fisik formula 3 yaitu, berbentuk serbuk berwarna hijau dengan bau khas daun kelor, kadar air 1,93%, daya alir 7,41 g/s, sudut diam 28,07°, waktu dispersi 72 detik, pH 6,47, dan ketinggian buih 2,6 cm. Hasil dari evaluasi formula 3 dengan konsentrasi sorbitol tertinggi tersebut memenuhi persyaratan. Selain itu, formula 3 juga menghasilkan rasa effervescent yang paling baik, yaitu dengan rasa manis asam dengan sensasi segar. Kata kunci : kelor, granul effervescent, sorbitol, Moringa oleifera
PHYSICAL AND ACTIVITY ACTIVITY TONER OF ESSENTIAL OIL OF BAY LEAF (SYZYGIUM POLYANTHUM) AGAINST PROPIONIBACTERIUM ACNE Anna Yusuf; Davit Nugraha; Marlina Indriastuti; Siti Rahmah KR; Laela Tri Fadila
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 9 No 2 (2024)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v9i2.1080

Abstract

Indonesian people have been using natural ingredients for generations as traditional medicines to treat various diseases or as a preventative measure. One of the plants often used is bay leaf (Syzygium polyanthum). Bay leaves (Syzygium polyanthum) contain 0.2% essential oil, with methyl chavicol, eugenol, and citral as the main compounds. The purpose of this study was to determine the physical properties of essential oil toner preparations from bay leaf plants (Syzygium polyanthum) and to understand the activity of the essential oil toner preparation from bay leaf plants (Syzygium polyanthum) against Propionibacterium acnes as an acne treatment. The physical test results produced the following data: organoleptic test, thin liquid form, distinctive bay leaf smell, clear slightly cloudy color, homogeneity test all preparations were homogeneous, pH test for average F0 5.75 ± 0.5016, F1 5.62±0.1039, F2 5.70±0.08083 and F3 5.64±0.05508 all met the requirements in the pH range of 4.5-6.5. ...
Co-Authors Andan Firmansyah Anna L Yusuf Anna Yusuf Atun Farihatun Ayu Fuji Astuti David Nugraha Davit Nugraha desi karningsih Ditha Septya Utami Esti Andarini Faisal Akbar Farah A Himah Henri Setiawan Laela Tri Fadila Lestari, Nina Indri Muhammad Jafar Shodiq Nia Kurniasih Nia Kurniasih Nina Muthoharoh Nita Asiah Nur Hidayat Nurhidayati Harun Oktapiana Rismaya panji wahlanto R, Susan Sintia Rahmah Kurnia R Restu Haniel Febrari Rian Ismail Rudi Kurniawan Siti Rahmah KR Siti Rahmah Kurnia Ramdan Siti Rahmah Kurnia Ramdan Veri Nugraha Windy Widyawatin Yudisa Diaz Lutfi Sandi