Garuda - Garba Rujukan Digital

p-Index From 2019 - 2024

2.223

P-Index

This Author published in this journals

All Journal Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Pharmasipha Journal of Tropical Pharmacy and Chemistry Jurnal FARMAKU (Farmasi Muhammadiyah Kuningan) ad-Dawaa : Journal of Pharmaceutical Sciences Mattawang: Jurnal Pengabdian Masyarakat Journal of Fundamental and Applied Pharmaceutical Science Proceeding of Mulawarman Pharmaceuticals Conferences Jurnal Pengabdian Masyarakat Farmasi : Pharmacare Society Acta Holistica Pharmaciana

Niluh Puspita Dewi

Sekolah Tinggi Ilmu Farmasi Pelita Mas Palu

Author-ID : 4024604

Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Education Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Public Health Social Sciences Other

Published : 17 Documents Claim Missing Document

Claim Missing Document

Articles

1 2

ANALISIS POLA PENGGUNAAN OBAT ANTIEPILEPSI DI INSTALASI RAWAT INAP RUMAH SAKIT UMUM DAERAH MADANI PROPINSI SULAWESI TENGAH Niluh Puspita Dewi
Jurnal Farmaku (Farmasi Muhammadiyah Kuningan) Vol 5 No 1 (2020): Volume 5 Nomor 1 Maret 2020
Publisher : STIKes Muhammadiyah Kuningan

Penyakit epilepsi adalah gangguan saraf yang timbul secara tiba-tba dan berkala, biasanya dengan perubahan kesadaran. Penelitian ini bertujuan untuk mengetahui karakteristik pasien epilepsi (jenis kelamin, usia, lama perawatan rawat inap, lama pengobatan) dan untuk menganalisis rasionalitas penggunaan obat yang meliputi ketepatan obat, ketepatan dosis, ketepatan frekuensi pemberian, ketepatan lama pemberian dan ketepatan penderita. Data yang digunakan secara retrsopektif yang diolah dengan menggunakan analisis deskriptif dalam bentuk persentase. Hasil penelitian menunjukkan bahwa data pasien epilepsi terbanyak berdasarkan jenis kelamin yaitu laki-laki sebanyak 56,67%, berdasarkan usia yaitu usia 27-37 tahun sebanyak 40%, berdasarkan lama rawat inap yaitu selama ≤ 7 hari sebanyak 66,67%. Obat-obat yang digunakan pasien epilepsi di RSUD Madani yaitu phenitoin 52 pasien, phenobarbital 25 pasien, carbamazepine 22 pasien, diazepam 15 pasien, dan asam valproate 10 pasien. Penggunaan obat pasien epilepsi di RSUD Madani tahun 2010-2012 sudah rasional.

POLA PENGOBATAN PENYAKIT DIARE PADA PASIEN PEDIATRIK DI RSU ANUTAPURA PALU TAHUN 2019 Niluh Puspita Dewi; Syafika Alaydrus; Putri Pratiwi
Pharmasipha: Pharmaceutical Journal of Islamic Pharmacy Vol 4, No 1 (2020): Maret
Publisher : University Of Darussalam Gontor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21111/pharmasipha.v4i1.3927

Diare merupakan penyebab utama kedua kematian pada anak-anak dibawah lima tahun dengan jumlah 760.000 kematian setiap tahunnya. Walaupun penyakit diare pada anak tidak menyebabkan kematian secara langsung, tetapi dapat berakibat fatal bila penanganannya tidak tepat. Penelitian ini bertujuan untuk mengetahui jenis dan golongan obat yang paling banyak digunakan dan menentukan ketepatan penggunaan antidiare pada pasien pediatrik di Ruang Rawat Inap di RSU Anutapura Palu Tahun 2019 dengan parameter tepat obat, tepat idikasi, tepat pasien, tepat dosis dan tepat frekuensi. Jenis penelitian menggunakan metode deskriptif dengan pengumpulan data secara prospektif dari bulan September-November Tahun 2019 terhadap pasien diare pada pediatrik di Rumah Sakit Umum Anutapura Palu yang memenuhi kriteria inklusi. Teknik pengambilan sampe secara accidental sampling. Hasil penelitian terhadap 55 pasien menunjukan penggunaan obat berdasarkan golongan obat yang paling banyak digunakan yaitu Antidiare (45,70%) dan penggunaan obat berdasarkan jenis obat yaitu Zink (20,60%). Berdasarkan ketepatan penggunaan obat Antidiare pada pasien diare pediatrik dengan parameter tepat indikasi (100%), tepat obat (100%), tepat dosis (100%), tepat frekuensi (100%), dan tepat pasien (100%).

Efek Antihiperkolesterol dan Antihiperglikemik Daun Ceremai (Phyllantus acidus (L.) Skeels) pada Tikus Putih Jantan (Rattus norvegicus) Hiperkolesterol Diabetes: Antihypercholesterol and Antihyperglicemic Effect of Ceremai Leaf (Phyllantus acidus (L.) Skeels) Extract on Hypercholesterolemia Diabetes White Male Mice (Rattus norvegicus) Dermiati tatto; Niluh Puspita Dewi; Feiverin Tibe
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 3 No. 2 (2017): (October 2017)
Publisher : Universitas Tadulako

Daun Ceremai (Phyllantus acidus (L.) Skeels) merupakan tanaman yang diyakini memiliki khasiat antihiperglikemik dan antihiperkolesterol serta didukung oleh sejumlah penelitian terdahulu yang menunjukkan bahwa daun ceremai mengandung senyawa kimia yang memiliki efek sebagai antihiperglikemik dan antihiperkolesterol. Penelitian ini merupakan penelitian lanjutan untuk mengetahui efek serta dosis efektif ekstrak daun ceremai dalam menurunkan kadar gula darah dan kolesterol total darah pada hewan uji tikus putih jantan model hiperkolesterolemia diabetes yang diinduksi pakan tinggi lemak dan streptozotocin dosis 30 mg/KgBB. Penelitian dilakukan menggunakan 40 ekor hewan uji yang dikelompokkan dalam 8 kelompok dengan perlakuan yaitu kelompok kontrol normal, kontrol positif simvastatin, kontrol positif metformin, kontrol negatif dan 4 kelompok uji dengan variasi dosis ekstrak masing-masing 50 mg/KgBB, 100mg/KgBB, 200 mg/KgBB dan 400 mg/KgBB. Hasil yang diperoleh menunjukkan bahwa ekstrak daun ceremai memiliki efek antihiperglikemik dan antihiperkolesterol secara bersama-sama terhadap tikus putih jantan model hiperkolesterol diabetes dengan dosis efektif 200 mg/KgBB.

Efektivitas Ekstrak Etanol Biji Alpukat (Persea americana Mill.) Terhadap Kadar Glukosa Darah Tikus Putih Jantan (Rattus Novergicus) Model Hiperkolesterolemia-Diabetes: Effectiveness of Ethanol Extract of Avocado Seeds (Persea americana mill.) on Blood Glucose Levels of Male White Rat (Rattus novergicus) Hipercolesterolemia-diabetes Model Recky Patala; Niluh Puspita Dewi; Meilinda Handayani Pasaribu
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 6 No. 1 (2020): (March 2020)
Publisher : Universitas Tadulako

Diabetes mellitus is a metabolic disorder characterized by increased blood glucose levels due to a deficiency of insulin secretion or when insulin resistance occurs. Herbal medicine is one alternative method that can be used to control blood glucose levels and prevent complications of diabetes mellitus. One of the medicinal plants is avocado seeds (Persea americana Mill.) The active compounds contained in avocado seeds that have antidiabetic activity are flavonoids, alkaloids, tannins and saponins. This study aims to determine the content of secondary metabolites in the extract of avocado seed, the effect of extract of avocado seed and the dose of extract of avocado seed that is effective in lowering blood glucose levels. This research was a laboratory experiment using a modified randomized controlled pretest and posttest group design. Test animals used were 30 rats which were divided into six treatment groups, namely normal control, negative control, positive control, a dose of 250, 300 and 350 mg/kg groups. The results showed that extract of avocado seed contained secondary metabolites: flavonoids, alkaloids, saponins, and tanins;extract of avocado seed gave effect to decrease blood glucose levels; extract of avocado seed with a dose of 350 mg/kg was effective in lowering blood glucose levelswith an avarage decrease of 99,8 mg/dL.

Ekstrak Etanol Daun Kacang Panjang (Vigna unguiculata (L.) Walp): Kajian Morfometri Insula Pankreatika Model Tikus Diabetes: Ethanol Extract of Some Cowpea (Vigna unguiculata (L.) Walp) Leaves: Morphometry Study of Pancreatic Islet of Diabetic Rat Model Puput Octaviani Solehah; Fikhta Agnesya Tarusu; Joni Tandi; Niluh Puspita Dewi; Gabriella Bamba Ratih Lintin; Yuli Fitriana; David Pakaya
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 5 No. 2 (2019): (October 2019)
Publisher : Universitas Tadulako

Diabetes is characterized by an increasing of blood levels and progressive changes in the structure of pancreatic islet of pancreas. Natural ingredients that contain antioxidants such as some cowpea leaves can be an alternative treatment for diabetes. This study aims to examine the effect of ethanol extract of some cowepea leaves (Vigna unguiculata (L.) Walp) on morphometry (perimeter and diameter) of pancreatic islet of diabetic rat models. The type of research is quasi-experimental with posttest group design. Samples were 30 male wistar rats, age 8 weeks, BW 250-300 grams, that induced by single dose of STZ 40 mg/kg BW. Rats were divided into 5 groups. Group A: normal control, Group B: negative control, Group C: positive control, Group D: DM rats with 100mg/Kg BW extract therapy, Group E: DM rats with 200mg/Kg BW extract therapy, Group F: DM rats with extract therapy 300mg/Kg BW. Blood sugar levels were measured on days 7, 14 and 21. Pancreatic tissue was prepared with 5μm thickness and stained with Hematoxylin Eosin. The sample was observed under 400x magnification microscope. The observation uses Image J software to measure the perimeter and diameter of the pancreatic insula. Data were analyzed by non-parametric Kruskal Wallis and post hoct Mann Whitney statistical tests. Blood glucose level was obtained on 21st day with the highest mean in group B (246.8±156.3) and lowest in group A (67.2 ±7.85), perimeter of pancreatic islet was significantly different (p=0.026), the diameter is significantly different (p =0.046). Ethanol extract of some cowpea (Vigna unguiculata (L.) Walp) leaves with dose of 300mg/kgBB helps to restore the blood and morphometry of pancreatic islet model of diabetic rats.

Potensi Rumput Laut (Eucheuma cottonii J.Agardh) Terhadap Nefropati Diabetik Tikus Putih Jantan (Rattus norvegicus): (Potency of Seaweed (Eucheuma cottonii J.Agardh) Against Nephropathy Diabetic Male White Rats (Rattus norvegicus)) Joni Tandi; Niluh Puspita Dewi; Resky Chandra Wirawan; Megawati R. Surat
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 6 No. 2 (2020): (October 2020)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24428744.2020.v6.i2.15046

ABSTRACT This study aims to determine the effect of a multilevel dose of ethanol extract of seaweed (Eucheuma cottonii J. Agardh) on the decreasing blood glucose levels and kidney tissue regeneration of hypercholesterolemia-diabetic male white rats. 24 rats were divided into 6 groups, namely groups 1-3 (normal control, negative control, and positive control/Glibenclamide, respectively) and groups 3-6 (seaweed extract doses of 100, 200, and 400 mg/kg BW per oral, respectively). Rats were induced by high fat diet and Streptozotocin. Histopathological picture of the kidney was observed by HE staining using 400 magnifications. Data scoring of the level of kidney damage were analyzed by One Way ANOVA at a 95% confidence level and a Least Significant Difference (LSD) test was conducted. Seaweed ethanol extract at a dose of 100 mg/kg BW was effective in reducing blood glucose levels with an average value of 122.25 mg/dL and effective in regenerating the kidney tissue of male white rats with an average value of damage of 1.9. Therefore, seaweed extract has potency to be developed and further investigated as an antidiabetic agent.

The Effect of Ethanol Extract of Guava (Psidium guajava L) Leaf on Hypercholesterolemia-Diabetic White Rats Male Induced by High Fat Feed and Streptozotocin Joni Tandi; Franciska Diana Pratiwi; surisna surisna; Niluh Puspita Dewi; Magfirah Magfirah
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 7 No. 2 (2021): (October 2021)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24428744.2021.v7.i2.15533

This study aims to determine the effect of guava (Psidiium guajava L) leaf extract on hypercholesterolemia-diabetic white rats male and the effective dose for reducing cholesterol and blood glucose levels. This study is a laboratory experimental study using 30 rats divided into 6 test animals. the treatment group, each group consisted of 5 rats. Group I was normal control, group II negative control was given Na-CMC suspension, group III as positive control was given simvastatin group IV dose 150 mg / kg BW, group V dose 250 mg / kg BW and group VI dose 350 mg / kg BW. The results showed that the ethanol extract of guava leaves influenced reducing blood glucose levels of male white rats with an effective dose of 250mg / kg BW with an average reduction of 119 mg/dL and effective reducing the cholesterol levels at a dose of 150 mg /kg BW with an average reduction of 28,33 mg/dL.

REVIEW OF DRUG DISTRIBUTION SYSTEM STRATEGY OF INPATIENT AT PROF. DR. MARGONO SOEKARJO HOSPITAL PURWOKERTO Niluh Puspita Dewi; Gunawan Pamudji; Aris Widiastuti
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 2, No 2
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.72

Decree of Minister of Health Number 1197/menkes/SK/X/2004 about Standard of Hospital Pharmacy Service, states that the Hospital Pharmacy Service was integral part of hospital health care system which oriented to patient care, provision of drugs quality, clinical pharmacy services, which affordable for all levels of society. Departement of Hospital Pharmacy (IFRS) was the only division were fully responsible for the management and control of all pharmaceuticals and other medical supplies which circulated and used in hospitals. Therefore IFRS should make appropriate strategies that start with the analysis of internal and external environments known as SWOT analysis to formulate strategy that can be implemented in the service of the IFRS. The research carried out by primary and secondary data collection regarding IFRS and direct observation in field conducted by the researchers. Research can be determined which factors into strengths, weaknesses, opportunities and threats that exist on Inpatient Drug Distribution System, which then made the determination of alternative strategies to be applied by using SWOT analysis and matrix QSP. The research results showed that the calculation results of internal evaluation matrix, strengths value of Inpatient Drug Distribution System in IFRS was greater than the weaknesses value at 0.32. The results of external factor evaluation matrix also the probability value was greater than the threat value at 0.06. Therefore Drug Distribution System of Inpatient at Prof. Dr. Margono Soekarjo Hospital located in quadrant 1, which supports policy of aggressive growth. Selection strategy by QSP matrix obtained results to improve the quality and quantity of human resources at 7.01; to establish patient visite program, at 7.43; to improve service quality in order to be more competitive with other pharmacies and hospitals at 7.28; and implement UDD distribution system at 7.66.Keywords: SWOT Analysis, Drug Distribution System of Inpatient.

Screening of Phytochemical Secondary Metabolites of Muntingia Calabura: a Potential as Hepatoprotector Elasari Dwi Pratiwi; Niluh Puspita Dewi
Journal of Fundamental and Applied Pharmaceutical Science Vol 2, No 2 (2022): February
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/jfaps.v2i2.12364

Muntingia calabura is one of the plants employed to produce herbal-based treatments. Muntingia calabura leaves are traditionally used as an alternative medicine due to their secondary metabolites. The maceration method extracted Muntingia calabura leaves using 96% ethanol solvent for 3 x 24 hours. The fractionation process was carried out using a separating funnel method with different polarities, such as n-hexane, ethyl acetate, and ethanol-water. Thin-layer chromatography (TLC) was used to confirm the phytochemical screening. TLC conditions under UV light 254 and 366 nm using solvents, such as chloroform: methanol (alkaloids), butanol: acetic acid: water (flavonoids), chloroform:methanol: water (saponins), and chloroform: methanol (phenolic). The phytochemical screening results of extracts and Muntingia calabura fractions contained secondary metabolites, such as alkaloids, flavonoids, tannins, saponins, and phenolics. TLC results showed that n-hexane fraction contained flavonoid and saponin compounds; ethyl acetate fraction contained alkaloids, flavonoids, saponins and phenolic compounds; and ethanol-water fraction contained alkaloids, flavonoids, saponins, and phenolics. Muntingia calabura leaves indicated the potential as herbal medicine by containing secondary metabolites.

Education on Handling Hypertension and Blood Pressure Checks at Petobo Huntara Central sulawesi: Edukasi Penanganan Penyakit Hipertensi dan Pemeriksaan Tekanan darah Di Huntara Petobo Sulawesi Tengah Syafika Alaydrus; Niluh Puspita Dewi; Wayan Wirawan; Ayu Wulandari
Mattawang: Jurnal Pengabdian Masyarakat Vol. 3 No. 1 (2022)
Publisher : Yayasan Ahmar Cendekia Indonesia

Hypertension is another name for high blood pressure. Blood pressure itself is the force of blood flow from the heart that pushes against the walls of blood vessels (arteries). Hypertension is a condition in which blood pressure is higher than 140/90 mmHG. This counseling was carried out by a team of Stifa Pelita Mas Palu lecturers totaling 4 people assisted by several students and carried out at Banua Huntara Petobo, with a total of 108 participants. Educational results based on discussions show that there are differences in knowledge about hypertension before and after being given education. Abstrak Hipertensi adalah nama lain dari tekanan darah tinggi. Tekanan darah itu sendiri adalah kekuatan aliran darah dari jantung yang mendorong dinding pembuluh darah (arteri). Hipertensi adalah kondisi di mana tekanan darah lebih tinggi dari 140/90 mmHG. Penyuluhan ini dilakukan oleh tim dosen Stifa Pelita Mas Palu yang berjumlah 4 orang di bantu beberapa mahasiswa dan dilakukan di Banua Huntara Petobo, dengan jumlah peserta sebanyak 108 orang. Hasil Edukasi berdasarkan diskusi menunjukkan bahwa ada perbedaan pengetahuan tentang hipertensi sebelum dan sesudah diberikan edukasi.

Co-Authors Aris Widiastuti Ayu Wulandari David Pakaya Debora Rislianti Lakiu Dermiati tatto DIAN RAHMAWATI Elasari Dwi Pratiwi Febry Grasela Aula Feiverin Tibe Fikhta Agnesya Tarusu Franciska Diana Pratiwi Gabriella Bamba Ratih Lintin Gunawan Pamudji Indah Kurnia Utami Indah Kurnia Utami Joni Tandi, Joni Magfirah - - Megawati R. Surat Meilinda Handayani Pasaribu Muthmainah Tuldjanah Patala, Recky Puput Octaviani Solehah Putri Pratiwi Ramla Allia Resky Chandra Wirawan Rezky Yanuarty Sri Mulyani Sabang surisna surisna Syafika Alaydrus Wayan Wirawan Wayan Wirawan Windi Olivia Kawanga Yuli Fitriana

Title

Found 17 Documents
Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title Search

Found 17 Documents Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title

Found 17 Documents
Search