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Journal : Viva Medika: Jurnal Kesehatan, Kebidanan dan Keperawatan

FORMULASI SEDIAAN MASKER ANTIOKSIDAN DARI EKSTRAK TEH HIJAU (CAMELLIA SINENSIS) desi nawangsari
Viva Medika Vol 11 No 3 (2018)
Publisher : Universitas Harapan Bangsa Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (298.03 KB) | DOI: 10.35960/vm.v10i2.451

Abstract

Abstract Research has been carried out on the formulation of maskantioxidant preparations containing green tea leaf extract. The study begins with testing the antioxidant activity of ethanol extract of green tea leaves with a free radical reduction method of 1,1-diphenyl-2-picrylhydrazyl using visible spectrophotometry. Testing of antioxidant activity showed that the ethanol extract of green tea leaves gave an IC50 value of 3.17µg / mL. Formulations of gel masks made were F0 (base without active substances), F1 (base + concentration of ethanol extract of green tea leaves for IC50 (0,000317%)), F2 (base + concentration of ethanol extract of green tea leaves for 50xIC50 (0, 0158%)), F3 (base + concentration of ethanol extract of green tea leaves for 100xIC50 (0.0317%)), F4 (base + concentration of ethanol extract of green tea leaves for IC50), F5 (base + concentration of ethanol extract of green tea leaves worth IC50), F6 (base + concentration of ethanol extract of green tea leaves for IC50. Evaluation of gel mask preparations include, organoleptic examination and homogeneity, pH, viscosity, dry time of preparation and testing of antioxidant stability. F2 provides better and higher free radical reduction activity than products on the market. F4, F5, F6 shows an increase in free radical reduction activity. Keywords: Green tea leaves (Camellia sinensis L.), DPPh, IC50 gel mask.
EVALUASI SEDIAAN MASKER ANTIOKSIDAN DARI EKSTRAK DAUN TEH HIJAU (CAMELLIA SINENSIS) desi nawangsari
Viva Medika Vol 11 No 3 (2018)
Publisher : Universitas Harapan Bangsa Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (298.358 KB) | DOI: 10.35960/vm.v10i2.452

Abstract

Abstract Green tea (Camellia sinensis L.) has the main efficacy as an antioxidant and contains polyphenol compounds in green tea leaves with the main component of polyphenol fraction namely Epigallocatechin-3-gallate (EGCG) which has strong activity to prevent free radicals that cause premature aging. Research has been carried out on the formulation of maskantioxidant preparations containing green tea leaf extract. The study begins with testing the antioxidant activity of ethanol extract of green tea leaves with a free radical reduction method of 1,1-diphenyl-2-picrylhydrazyl using visible spectrophotometry. Testing of antioxidant activity showed that the ethanol extract of green tea leaves gave an IC50 value of 3.17µg / mL. Formulations of gel masks made were F0 (base without active substances), F1 (base + concentration of ethanol extract of green tea leaves for IC50 (0,000317%)), F2 (base + concentration of ethanol extract of green tea leaves for 50xIC50 (0, 0158%)), F3 (base + concentration of ethanol extract of green tea leaves for 100xIC50 (0.0317%)), F4 (base + concentration of ethanol extract of green tea leaves for IC50), F5 (base + concentration of ethanol extract of green tea leaves worth IC50), F6 (base + concentration of ethanol extract of green tea leaves for IC50. Evaluation of gel mask preparations include, organoleptic examination and homogeneity, pH, viscosity, dry time of preparation and testing of antioxidant stability. F2 provides better and higher free radical reduction activity than products on the market. F4, F5, F6 shows an increase in free radical reduction activity. Keywords: Green tea leaves (Camellia sinensis L.), DPPh, IC50 gel mask.
Pengaruh Bahan Pengisi Terhadap Massa Cetak Tablet Vitamin C Desy Nawangsari
Viva Medika Vol 12 No 02 (2019): Viva Medika: Jurnal Kesehatan, Kebidanan, dan keperawatan
Publisher : Universitas Harapan Bangsa Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (499.805 KB) | DOI: 10.35960/vm.v11i02.464

Abstract

Avicel® PH is branded name from microcrystalline cellulose that is generally used in pharmaceutical preparations. Avicel® PH are being used as filler or binder in dosage formulas in tablets especially for direct compression because having a good flowing rate and a good compressibility. This study aims to compare the influence of the use Avicel® PH 101 and Avicel® PH 102 as a filler on of preparations a tablet of ascorbic acid. A method of the research was conducted by making granule of ascorbic acid tablet with the variation filler, then the granule was evaluate in .The results showed Avicel® PH 102 as a filler produce granule which better seen from the flowability, static angle of repose, carr’s index and hausner ratio .
PREPARASI DAN ISOLASI MIKROKRISTAL DARI AMPAS TEBU (Saccharum officinarum L.) Desy Nawangsari; Rani Pranbandari; Fenny Permatasari
Viva Medika Vol 13 No 01 (2019): VOLUME 13/NOMOR 01/SEPTEMBER/2019
Publisher : Universitas Harapan Bangsa Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (511.347 KB) | DOI: 10.35960/vm.v12i01.487

Abstract

Selulosa mikrokristal merupakan hasil isolasi dari alfa selulosa. Selulosa mikrokristal banyak digunakan dalam bidang farmasi. Salah satu bahan alam yang dapat dimanfaatkan untuk membuat selulosa mikkrokristal adalah ampas tebu. Ampas tebu mengadung 45,96% selulosa yang dapat diisolasi dengan tahapan delignifikasi menggunakan larutan basa, proses pemutihan serta hidrolisis alfa selulosa dengan pemanasan suhu tinggi menggunakan larutan asam encer. Rendemen selulosa mikrokristal dari ampas tebu 26,03%.
ISOLASI DAN IDENTIFIKASI RIMPANG TEMULAWAK (Curcuma xanthorrohza Roxb.) DAN BUNGA LAVENDER (Lavandula angustifolia Mill.) rani prabandari; desy Nawangsari; Kukuh Yunianto Sumargo
Viva Medika Vol 13 No 01 (2019): VOLUME 13/NOMOR 01/SEPTEMBER/2019
Publisher : Universitas Harapan Bangsa Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (362.447 KB) | DOI: 10.35960/vm.v12i01.488

Abstract

Essential oils are fragrance agents in plants. Essential oils have a volatile component in some plants with certain characteristics. At present, essential oils have been used as perfume, cosmetics, food additives and medicine. Empiric ethnopharmacology studies on aromatherapy plants show that Indonesia has 49 types of aromatic plants from 22 types of tribes, 12 of which are empirically used as aromatherapy with calming and refreshing effects (Sangat 1996 in Rahmawati, 2010). One example of aromatherapy used is the ginger rhizome (Curcuma xanthorrihza Roxb) and Lavender Flower (Lavandula angustifolia Mill.). This study aims to isolate and identify the essential oils of Temulawak rhizome (Curcuma xanthorrihza Roxb) and Lavender Flowers (Lavandula angustifolia Mill.). The essential oil isolation step uses the Steam Water Distillation method, after which the essential oil obtained is identified to ensure its purity. The results showed that Temulawak essential oil and Lavender essential oil were carried out using the water distillation method, obtained levels of 2.3% and 1.8%. Essential oils in Temulawak were identified by testing their physical properties which include specific gravity, solubility in ethanol 90%, solubility in chloroform and oil in NaCl. The identification results obtained in the Temulawak rhizome and Lavender plants are specific gravity 0.9436 and 0.8221. Solubility in ethanol 90% with a volume ratio of 1: 3.7 mL and 1: 3.3 mL. solubility in chloroform of 1: 3.3 mL and 1: 3.3 mL. on the addition of NaCl in the oil oil reduction occurs.