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All Journal Indonesian Journal of Pharmaceutical Science and Technology Pharmacon Journal of Pharmacopolium Jurnal Mandala Pharmacon Indonesia Viva Medika: Jurnal Kesehatan, Kebidanan dan Keperawatan Jurnal Dunia Farmasi Jurnal Farmasi dan Sains Indonesia (JFSI) Journal of Nursing and Health (JNH) Akper Yakpermas Banyumas Jurnal Ilmiah Farmasi Akademi Farmasi Jember Jurnal Pengabdian Masyarakat Pharmacy Genius SEMINAR NASIONAL PENELITIAN DAN PENGABDIAN KEPADA MASYARAKAT
Desy Nawangsari
Universitas Harapan Bangsa
Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Other

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Journal : Jurnal Farmasi dan Sains Indonesia (JFSI)

 1 
Evaluasi Sifat Fisik Dan Uji Iritasi Sediaan Sabun Wajah Ekstrak Etanol Biji Salak Pondoh (Salacca zalacca (Gaert.) Voss) Rafi Firman Khaqiqi; Desy Nawangsari; Rani Prabandari
Jurnal Farmasi & Sains Indonesia Vol 5 No 1 (2022)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol5no1p46-52

Abstract

One of the beneficial parts in salak pondoh is the seeds. Salak pondoh seeds have antioxidant activity that can counteract free radicals. This potential can be utilized in the formulation of facial cleansing cosmetics. The purpose of this study was to formulate the ethanolic extract of salak pondoh seeds into a facial soap, then tested the physical properties and tested for acute irritation. The ethanol extract of salak pondoh seeds was formulated in several concentrations, namely 1%, 3% and 5%. Evaluation of the physical properties includes organoleptic tests, pH tests, foaming tests, viscosity tests and spreadability tests. The acute dermal irritation test used a rabbit. The data obtained were statistically tested using the one-way ANOVA method to determine the difference between each formula. The results is a brown liquid facial soap (with extract) and white (without extract). Evaluation of the physical properties resulted pH and foaming tests according to standards but viscosity and spreadability did not match. The non-fulfillment of the viscosity standards and the spreadability caused by the Viscosity Modifier (NaCl) in the formula needs to be adjusted further. This facial soap is moderately irritant to animal skin. The irritation is thought to occur because Sodium Lauryl Sulfate (SLS) in the formula can affect erythema and edema in the test animals. Keywords: salak pondoh seeds, facial soap, physical properties, irritation test
Formulasi dan Uji Sifat Fisik Sediaan Masker Wajah Ekstrak Etanol Daun Mangga Arumanis (Mangifera indica L.)) Yeni Pratiwi; Desy Nawangsari; Dina Febrina
Jurnal Farmasi & Sains Indonesia Vol 5 No 1 (2022)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol5no1p53-59

Abstract

Mangga merupakan tanaman yang memiliki banyak manfaat. Daun mangga arumanis memiliki aktivitas antibakteri yang mampu menghambat pertumbuhan sel bakteri. Mangiverin yang terkandung dalam daun mangga arumanis (Mangivera indica L.) mempunyai efek sebagai antimikroba. Ekstrak daun mangga arumanis diformulasikan dalam bentuk masker bubuk dengan kombinasi tepung beras untuk menghasilkan efek yang sinergis. Penelitian ini bertujuan untuk mengetahui pengaruh sifat fisik dan stabilitas sediaan setelah dan sebelum dilakukan uji cycling test. Masker bubuk dibuat dalam tiga formula dengan memvariasikan konsentrasi tepung beras dan ekstrak daun mangga arumanis yaitu dengan perbandingan F(1) 2:8, F(2) 4:6 dan F(3) 6:4. Secara organoleptic masker yang dihasilkan pada F(1) berwarna putih kecoklatan, bau khas, tekstur setengah padat, untuk F(2) dan F(3) berwarna kuning kecoklatan, bau khas dan tekstur setengah padat. Hasil uji homogenitas semua formula homogen,uji pH F(1) 6,3, F(2) 6,0 F(3) 5,8, uji daya lekat F(1) 33,90 detik, F(2) 33,56 detik, F(3) 30,37 detik, waktu mengering F(1) 33,90, F(2) 33,56, F(3) 30,37 menit dan uji daya sebar baik. Dapat disimpulkan bahwa masker yang dihasilkan memiliki karakteristik yang baik.
FORMULASI SEDIAAN PASTA GIGI DENGAN ARANG AKTIF TEMPURUNG KELAPA (Cocos nucifera L) SEBAGAI PEMUTIH GIGI Liana Febrianti; Desy Nawangsari; Adita Silvia F
Jurnal Farmasi & Sains Indonesia Vol 4 No 2 (2021)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol4no2p50-57

Abstract

Teeth are one of the important aesthetic factors for a person, including tooth color. The effect of tooth discoloration can cause a person's lack of self-confidence. The use of teeth whitening materials can cause side effects in the oral cavity so that the use of natural ingredients is chosen as a tooth whitener, one of which is activated charcoal. Activated charcoal has an absorption capacity of 25-100%. The purpose of this study was to determine the activity of coconut shell-activated charcoal toothpaste as a teeth whitener. This study used 20 dentures and then soaked them in coffee solution for 17 days to change the color of the teeth. Tooth color was measured using a classical Vitapan shade guide. Teeth whitening activity test was carried out for 14 days. Toothpaste was made in 4 formulas with different concentrations of coconut shell-activated charcoal in formula 1 (0%), formula 2 (6%), formula 3 (10%), and formula 4 (12%). The results of the observation showed that the preparation of coconut shell-activated charcoal toothpaste can give tooth discoloration. A statistical tests showed that coconut shell-activated charcoal toothpaste had a significant difference in activity as a natural ingredient for whitening teeth.
FORMULASI, SIFAT FISIK DAN UJI AKTIVITAS ANTIOKSIDAN MASKER GEL PEEL OFF TEPUNG BERAS HITAM (Oriza sativa L. var Indica) Mely Nastiti; Desy Nawangsari; Dina Febrina
Jurnal Farmasi & Sains Indonesia Vol 4 No 2 (2021)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol4no2p58-67

Abstract

Black rice (Oriza sativa L. var Indica) is a local variety that contains anthocyanin pigments. Anthocyanins are antioxidants that have a positive effect on health. Peel off face mask is a face mask that has the advantage that it is easy to remove like an elastic membrane. This study aims to determine the physical evaluation of the peel off gel mask preparation, antioxidant activity and stability of the peel off gel mask. This research method was carried out experimentally, the data were analyzed using the One Way ANOVA method with sig > 0.05. The conclusion of this study was that the black rice flour peel off mask preparation had a significant significant difference to the f1 dispersion test, but there was no significant difference between f2 and 3. There was no significant difference in the antioxidant test. Based on data analysis using one way ANOVA after the cycling test, the formulation was good for 6 cycles, namely formulations 2 and 3. Keywords: Antioxidant, Black rice, dan Peel off mask.
FORMULASI SEDIAAN GEL SCRUB WAJAH SERBUK BIJI KOPI ARABIKA (Coffee arabica) DENGAN KONSENTRASI KARBOPOL 940 SEBAGAI GELLING AGENT Natasha Faruqi Andrian Putri; Desy Nawangsari; Sunarti Sunarti
Jurnal Farmasi & Sains Indonesia Vol 4 No 2 (2021)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol4no2p68-73

Abstract

ABSTRACT Coffee is a plant that is rich in benefits. Arabica coffee beans contain antioxidants that can provide benefits, one of which is preventing cell damage due to exposure to free radicals. Arabica coffee is formulated in the form of a gel scrub with the gelling agent carbopol 940. This study aims to determine the best concentration of gelling agent on the physical properties and stability of the Arabica coffee bean gel scrub and when used it causes irritation or not. Pure experimental research method to determine the effect of certain treatments by comparing with the control group that was not given treatment. Evaluation of gel scrub preparations included evaluation of the physical quality of the preparation and irritation test on 3 rabbits. The results of the evaluation of the preparations showed that all gel scrub preparations were in the form of a gel with black granules, distinctive smell, homogeneous, stable during 6 cycles of storage, pH value (4.5-7.8), adhesion (2-300 seconds), spreadability (5-7 cm) and viscosity (2000-4000 cp), irritation test in rabbits caused a slight irritating skin reaction. The results of the statistical test with the one way anova test showed that there was a significant difference between the formulas with a significance value (p < 0.05). However, the stock can still be said to be stable because it is still in the range of requirements. In conclusion, the gel scrub produced has good physical characteristics and causes a slight irritation of the skin reaction. Arabica coffee bean powder can be formulated as a gel scrub preparation which has good physical characteristics in formula IV with a concentration of carbopol 940 2%. and stable at 6 cycles of storage.
AKTIVITAS EKSTRAK ETANOL DAUN KELOR (Moringa oleifera L.) PADA SEDIAAN SALEP BASIS ABSORPSI TERHADAP BAKTERI Propionibacterium acne Restu Maulana; Rani Prabandari; Desy Nawangsari
Jurnal Farmasi & Sains Indonesia Vol 7 No 1 (2024)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol7no1p65-77

Abstract

Moringa leaves contain flavonoids, alkaloids, saponins and tannins that can inhibit bacterial growth. In order to make the use of moringa leaves more practical, an absorption base ointment formulation was made. Ointment preparations were chosen because they are suitable for medicinal purposes on the skin because the drug contact with the skin is longer. This study aims to determine the physical properties, stability and antibacterial activity of absorption base ointment preparations of moringa leaf ethanol extract. The research method is experimental laboratory. The extract concentrations used were F0 (base), F1 (15%), F2 (20%) and F3 (25%). Physical quality testing is seen from organoleptic, homogeneity, pH, spreadability and stickiness. The pH test results were sequentially obtained as 6.33 ± 0.15, 5.9 ± 0.1, 5.6 ± 0.1 and 5.56 ± 0.15. The spreadability test sequentially obtained 2.87 ± 0.07, 2.9 ± 0.05, 3.05 ± 0.05 and 3.25 ± 0.1 cm. The stickiness test was 17.60 ± 0.60, 17.59 ± 0.46, 16.87 ± 0.47 and 16.18 ± 0.56 seconds. The results were analyzed using SPSS 26 with One Way ANOVA, there were significant differences in pH values, spreadability and adhesiveness with a significance value of <0.05. The results of the stability test with the Cycling test method analyzed by T-test there was no significant difference from each formula between day 0 and day 12 with a 2-tailed value >0.05 which means that the formulas made are all stable in the stability test. Formula 1, 2 and 3 can inhibit Propionibacterium acne bacteria with an average inhibition zone of F1 10.34 ± 1.86 mm, F2 13.77 ± 3.43 mm and F3 16.67 ± 0.97 mm. It can be concluded that the three formulas have strong inhibition.
Co-Authors Adita Silvia F Adita Silvia Fitriana Aditya Silvia Fitriana Alfaeni Salmatuzzahro Alviony Trista Hapsari Anis Fitria Yuliani dina febrina Dwi Mustikasari Dwi Syaji Wahyuningtias Ega Angelia Narki Fenny Permatasari Galih Samodra Ikhwan Yuda Kusuma Isti Nurfaizah Khamdiyah Indah Kurniasih Kukuh Yunianto Sumargo Liana Febrianti Lina Umami LINDA APRIYANTI, LINDA Made Suandika Marline Abdassah, Marline Mely Nastiti Natasha Faruqi Andrian Putri Nur Khasanah Pegi Erawati Peppy Octaviani Rafi Firman Khaqiqi Rani Prabandari Rani Prabandari Rani Pranbandari Restu Maulana Rizky Widya Ayuning Tias Sriwidodo Sriwidodo, Sriwidodo Sunarti Sunarti Taofik Rusdiana umi sangadah Vidia Putri Kusumandari Yeni Pratiwi Yohana Chaerunisaa, Anis