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GERAKAN MASYARAKAT CERDAS MENGGUNAKAN OBAT (GeMA CerMat) PENCEGAHAN RESISTENSI ANTIBIOTIK PADA SISWA SISWI SMA DI KOTA KENDARI Sabarudin, Sabarudin; Sahumena, Muhamad Handoyo; Mistryani, Mistryani; Rahman, Sudarman
Jurnal Pengabdian Masyarakat Ilmu Terapan (JPMIT) Vol 1, No 1 (2019)
Publisher : Vokasi Universitas Halu Oleo

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (2301.026 KB) | DOI: 10.33772/jpmit.v1i1.9387

Abstract

Antibiotic resistance to bacteria causes very dangerous consequences. Infectious diseases caused by bacteria that are not successful in treatment result in a prolonged illness. Some important aspects that must be considered regarding antibiotics include; Appropriate use, the selected antibiotic is the right antibiotic, only used for bacterial infections. The purpose of this service is intended to provide knowledge among students, especially high school students regarding the importance of preventing antibiotic resistance. The method used is the lecture method with the intention to provide direct understanding to the students of SMAN 10 Kendari and SMK Kesehatan on how to use antibiotics properly and correctly so that antibiotic resistance does not occur. Socialization begins with an explanation of the general definition of antibiotics, antibiotic classification, how to use antibiotics correctly and an explanation of the dangers of antibiotic resistance. Incorrect drug use often occurs in the community due to incomplete information delivered by health workers when giving drugs. The next socialization was an explanation of the procedure for storing and disposing of medicines that were good and right. Storage of drugs really needs to be considered to maintain the quality of medicinal products used, especially if the drug products run out in a long time. It is hoped that through this activity the objectives to be achieved can be realized and students and the community become more attentive in the use of antibiotics correctly.
Pemanfaatan Tanaman Obat Keluarga (TOGA) dalam Pencegahan dan Pemulihan Penderita Akibat COVID-19 melalui KKN Tematik Universitas Halu Oleo (UHO) di Kabupaten Kolaka: Utilization of Family Medicinal Plants (TOGA) in the Prevention and Recovery of COVID-19 Sufferers by KKN Tematik of Universitas Halu Oleo (UHO) in Kolaka District Idin Sahidin; Ruslin Ruslin; Sudarman Rahman
Jurnal Mandala Pengabdian Masyarakat Vol. 1 No. 2 (2020): Jurnal Mandala Pengabdian Masyarakat
Publisher : Progran Studi Farmasi STIKES Mandala Waluya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (550.789 KB) | DOI: 10.35311/jmpm.v1i2.9

Abstract

Sufferers of Covid-19 in Southeast Sulawesi Province was continue to increase and until now there is no drug that can kill the virus. Therefore, to prevent, reduce and improve the recovery of Covid-19 cases is done by preventing and reducing the corona virus effects such as fever and shortness of breath. These activities include prevention from outside (external) using disinfectants and antiseptics, as well as prevention from within (internal) through increased immunity. Procurement of disinfectants, antiseptics, immune enhancements is done by utilizing family medicinal plants (TOGA) which can be scientifically justified. The method of this activity includes the socialization of the manufacture and use of disinfectants, handsanitisers and fresh drink made from TOGA in Sub-district of Watubangga, Regency of Kolaka through the Thematic Community Service (KKN) Program of Universitas Halu Oleo. TOGA used consists of turmeric (Curcuma domestica), lime (Citrus aurantifolia), betel (Piper bettle), lemongrass (Cymbopogon citratus), ginger (Curcuma xanthorrhiza) and ginger (Zingiber officinale).
PENCEGAHAN DEMAM BERDARAH MENGGUNAKAN LILIN ANTI NYAMUK Stevin Carolius Angga; Erwin Prasetya Toepak; Desimaria Panjaitan; Ika Oktavia Wulandari; Agus Lasono; Sari Namarito Simamarta; Sudarman Rahman
LOGISTA - Jurnal Ilmiah Pengabdian kepada Masyarakat Vol 5 No 2 (2021)
Publisher : Department of Agricultural Product Technology, Faculty of Agricultural Technology, Universitas Andalas Kampus Limau Manis - Padang, Sumatera Barat Indonesia-25163

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/logista.5.2.82-86.2021

Abstract

Penyakit demam berdarah merupakan masalah kesehatan masyarakat di Indonesia terutama pada musim penghujan. Penyakit ini ditularkan oleh virus dengue melalui nyamuk Aedes aegypti. Provinsi Kalimantan tengah menempati urutan tiga besar dalam angka penyakit demam berdarah. Salah satu penangangan yang dapat dilakukan untuk melakukan pencegahan demam berdarah adalah dengan memanfaatkan bahan alam yaitu ekstrak dari serai (Cymbopogon citratus) atau serai wangi (Cymbopogon nardus). Pada umumnya serai digunakan sebagai bumbu dapur, sementara serai wangi tidak terlalu dimanfaatkan. Memperhatikan hal-hal tersebut, maka pembuatan lilin anti nyamuk dari ekstrak serai wangi dapat menjadi salah satu solusi dalam mengatasi penyakit demam berdarah dan pengetahuan ini patut disosialisasikan kepada masyarakat. Metode yang digunakan dalam sosialisasi ini berupa ceramah dan pembagian sampel lilin anti nyamuk. Sementara materi ceramah yang disosialisasikan adalah tentang bahaya penyakit demam berdarah, pencegahannya, pemanfaatan serai wangi sebagai alternatif pencegahan demam berdarah dalam bentuk lilin, teknik pembuatan lilin anti nyamuk. Kegiatan ini diharapkan dapat membantu pemerintah dan masyarakat desa Tumbang Nusa Kabupaten Pulang Pisau dalam penanganan penyakit demam berdarah. Selain itu, kegiatan ini diharapkan dapat meningkatkan kesadaran masyarakat tentang kesehatan dalam mencegah penyakit deman berdarah. Kata kunci: sosialisasi, demam berdarah, serai wangi, lilin anti nyamuk, minyak atsiri ABSTRACT Dengue fever disease is a public health problem in Indonesia, especially during the rainy season. This disease is transmitted by the dengue virus through Aedes aegypti mosquito. Central Kalimantan is the top three in terms of dengue fever disease. Meanwhile, there are Kalimantan natural products which can be used as repellent to prevent the mosquito, such as extracts from lemongrass (Cymbopogon citratus) or citronella grass (Cymbopogon nardus). Mostly lemongrass is used as a kitchen spice, while citronella grass is not very used generally. Furthermore, the utilization of mosquito repellent candles from citronella extract could be a solution to overcome dengue fever disesase. The method used in this socialization is in the form of lectures and distribution of mosquito repellent candle samples. While the lecture material that was socialized was about the dangers of dengue fever, its prevention, the use of citronella grass as an alternative to dengue fever prevention in the form of candles, and preparation of mosquito repellent candles. This socialization is expected to supports the government and the community of Tumbang Nusa village, Pulang Pisau Regency to overcome the dengue fever disease. In addition, this activity is expected to increase public awareness about health in preventing dengue fever. Keywords: socialization, dengue fever, citronella grass, mosquito repellent candle, essential oil
Profil fitokimia dan aktivitas antibakteri fraksi etil asetat akar jarak pagar (Jatropha curcas Linn.) Sudarman Rahman; Stevin Carolius Angga; Erwin Prasetya Toepak; Muhammad Takdir Bachtiar
Sasambo Journal of Pharmacy Vol. 2 No. 2 (2021): September
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (383.8 KB) | DOI: 10.29303/sjp.v2i2.116

Abstract

Bacterial infections are a major cause of chronic infections and mortality that continues to threaten public health worldwide. Various medicinal plants used in folk medicine have demonstrated wound healing and antibacterial properties. The aims of the study are investigation phytochemical and antibacterial activity of ethyl acetate fraction from jarak pagar roots (Jatropha curcas Linn.). The roots were treated with maceration method using ethanol 70% and subsequently fractioned to ethyl acetate fraction. The fractions were used for phytochemical screening and antibacterial assay using Kirby and Bauer agar difussion method. The results showed that ethyl acetate fraction jarak pagar roots contained alkaloid, flavonoids, saponins, steroids, poliphenol dan tannins. The antibacterial activity of jarak pagar roots againts Staphylococcus aureus and Escherichia coli shows that the activity of this fraction with concentration 8 mg/mL has strong inhibitory potency against the growth S. aureus with inhibitory zone is 14,3 mm and has moderate inhibitory potency against E. coli with inhibitory zone is 9 mm. The increase concentrations of ethyl asetate fraction jarak pagar roots shows high inhibition diameter of bacterial growth.  
Penguatan peran warga masyarakat dalam mitigasi dan adaptasi menghadapi wabah Covid-19 di Kabupaten Kolaka Sudarman Rahman; Sahidin Sahidin
INDRA: Jurnal Pengabdian kepada Masyarakat Vol. 2 No. 1 (2021): April
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (457.771 KB) | DOI: 10.29303/indra.v2i1.51

Abstract

WHO China Country Office reported pneumonia cases in Wuhan, Hubei Province, China. The virus was lately identified as a new strain of corona virus called Severe Acute Respiratory Syndrome Coronavirus-2. The new cases grow massively and became pandemic. Regarding this rapid transmission, there is a need for socialization to strengthen people’s awareness and role in mitigation and adaptation against this  COVID-19 pandemic. The method used was counseling with socialization or lectures and supported interactions in the form of questions and answers by using power points and leaflets/brochures as information media. This community engagement included the activities of the Movement for Healthy Living Society (GERMAS), Clean and Healthy Living Behavior (PHBS), Use of Personal Protective Equipment such as using masks, Use of Antiseptics and Disinfectants, and Planting Family Medicines (TOGA). The implementation of this activity began with socialization to the local community at the village hall, then to the houses of residents to deliver the subject contained in the brochure/leaflet, and last by placing pamphlets in public places to provide information to the community related to the activities that had been done. This socialization is expected to increase public awareness to face against this corona virus disease outbreak.
Design of Vaccine Candidate Based on Ebola Virus Epitop With In Silico Approach Erwin Prasetya Toepak; Sari Namarito Simarmata; Sudarman Rahman; Stevin Carolius Angga
Jurnal Sains dan Terapan Kimia Vol 16, No 1 (2022)
Publisher : Program Studi Kimia, Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (720.028 KB) | DOI: 10.20527/jstk.v16i1.12167

Abstract

ABSTRACT          The World Health Organization (WHO) recorded as many as 2,299 cases of death with a case percentage of 66% during 2018 to 2020 in the Democratic Republic of the Congo due to the Ebola virus. Ebola virus is a member of the Filoviridae family. One of the viro cores consists of glycoprotein (GP). Messenger RNA (mRNA) generates long GP chains for the attachment protein (GP 1) and the fusion protein (GP 2). Epitope-based vaccines are a promising approach because epitopes represent immunogenic regions that elicit immunity specifically. Epitope prediction was performed based on the GP EBOV sequence available in the Data Bank. The designed vaccine could be one of the candidates for the Ebola virus vaccine. The design of the virus with access to NCBI AAB81004 was carried out by testing such as B cell epitope, T cell, and their antigenicity using the VaxiJen v2.0 server and IEDB. The T cell epitope prediction results showed that 20 T cell epitopes interacted with the Major Histocompatibility Complex (MHC) with the highest score of 2.8069. B cell epitope by linear BepiPred assay had 77 candidate epitope peptides from sequence 401-477. Karplus and Schulz's flexibility predictions showed a predictive value of 1.119 with a threshold of 1.008, with the analyzed area having an antigenic tendency where the threshold area was yellow. Keywords: Ebolavirus; Vaccine; Epitope B Cell; Epitope T Cell; In Silico
Uji aktivitas antioksidan dan sitotoksik ekstrak daun Jarak Pagar (Jatropha curcas) Sudarman Rahman; Erwin Prasetya Toepak; Stevin Carolius Angga; Ysrafil Ysrafil
Jurnal SAGO Gizi dan Kesehatan Vol 4, No 2 (2023): Juni
Publisher : Politeknik Kesehatan Kemenkes Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30867/gikes.v4i2.1175

Abstract

Background: antioxidants play an important role in preventing cell damage and generating inhibition of signalling pathways of cancer, aging and various diseases. Several extracts, oils, and herbal formulations were shown to be important Antioxidant agents for preventing cell damage. Jarak Pagar (Jatropha Curcas) leaves. were a common natural Antioxidant phytochemical screening of Jatropha leaves that contained flavonoids, where flavonoids acted as antioxidants.Objectives: this study aims to determine the Antioxidant and cytotoxic activity of ethanol extract of Jatropha leaves using the DPPH and shrimp larvae method, respectively.Methods: the design in this study was quasi-experimental, using various concentrations of ethanol extract and vitamin C (comparison control) in inhibiting free radicals and each Concentration was repeated three repetitions. The research was conducted at the Laboratory of Chemistry FMIPA Palangka Raya University and Chemistry Education FKIP Halu Oleo University in 2022. The ethanol extract of Jatropha leaves weighing 60 grams was extracted using the Soxhletion method to obtain 1.667 grams of thick ethanol extract. Phytochemical characterization was further conducted by tube method, Antioxidant tests by DPPH (1,1-diphenyl-2-picrylhydrazyl) and cytotoxic test assessed by the Brine Shrimp Lethality Test (BSLT) method. The data analysis used the One Way Anova statistical test and continued with post hoc Tamhane at 95% Cl.Results: the results showed that Jatropha curcas L. leaves contained several secondary metabolites such as flavonoids, saponins, alkaloids, polyphenols and tannins. Furthermore, the Antioxidant activity test of ethanol extract of Jatropha curcas L leaves and control (vitamin C) provided IC50 of 32.83 ± 0.09 (μg/mL) and 8.78 ± 0.21 (μg/mL), respectively. Another finding found that ethanol extract of Jatropha leaves contained active compounds that were toxic to shrimp larvae with LC50 of 427 ppm. Based on the One Way Anova test, each Concentration had a significant difference in the percentage of radical scavenging (p= 0,05). The Concentration of 160 ppm is the most effective in radical scavenging.Conclusion: we concluded that the ethanol extract of Jatropha leaves showed strong Antioxidant activity and potential as an anticancer agent
GREEN ECONOMY THROUGH DISTILLATION TECHNOLOGY TRANSFER OF CITRONELLA PLANTS ESSENTIAL OILS Rokiy Alfanaar; Yahya Febrianto; Shesanti Citra Riana; Sudarman Rahman; Awalul Fatiqin; Febri Nur Ngazizah; Karyadi Karyadi; Yudhi Ekakristian Sahari; Mu'afa Purwa Arsana; Thathit Suprayogi
JMM (Jurnal Masyarakat Mandiri) Vol 7, No 5 (2023): Oktober
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jmm.v7i5.17535

Abstract

Abstrak: Green economy merupakan salah satu jenis ekonomi yang memperhatikan aspek lingkungan. Konsep green economy melibatkan pemanfaatan tanaman sebagai sumber daya terbarukan dalam bidang ekonomi. Sebagai kabupaten yang baru keluar dari status 3T, Seruyan memiliki potensi pengembangan ekonomi dalam bidang green economy. Pengabdian ini bertujuan mengenalkan green economy melalui transfer teknologi destilasi minyak atsiri dengan tanaman yang digunakan adalah Serai Wangi yang lazim ditemukan di Desa Bukit Buluh. Metode pelaksanaan pengabdian terdiri dari merancang alat destilasi dan pelatihan pemanfaatan alat destilasi yang dihadiri 23 peserta dari warga dan pengurus desa dengan peningkatan pemahaman dalam bidang rangkaian distilasi, pemilihan tanaman, dan optimasi ekstraksi sebanyak 95, 60, dan 85 %. Kegiatan pengabdian ini berjalan dengan baik dengan tingginya antusiasme warga dalam kegiatan pelatihan.Abstract: Green economy is an economic model that prioritizes environmental considerations. The concept of the green economy revolves around utilizing plants as renewable resources within the economic sector. Seruyan, recently emerged from 3T status, holds substantial potential for economic growth within the realm of the green economy. The purpose of this initiative is to introduce the principles of a green economy by imparting knowledge about essential oil distillation technology, using Lemongrass as the primary plant source, abundantly available in Bukit Buluh Village. The method of implementing the service consisted of designing distillation equipment and training on the utilization of distillation equipment which was attended by 23 participants from residents and village administrators with an increase in understanding in the fields of distillation circuit, plant selection, and extraction optimization by 95, 60, and 85%. This service activity went well with the high enthusiasm of the residents in the training activities.
Mengurangi Emisi Gas Metana Dengan Mengolah Limbah Cair Tempe Menjadi Biogas Zimon Pereiz; Zahrotun Nafisah; Sudarman Rahman; Meiyanti Ratna Kumalasari
Nanggroe: Jurnal Pengabdian Cendikia Vol 2, No 6 (2023): September
Publisher : Yayasan Daarul Huda Kruengmane

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5281/zenodo.8393970

Abstract

Biogas merupakan salah satu bentuk energi alternatif yang terbaharukan dan dapat diterapkan kepada masyarakat sebagai bentuk efisiensi penggunaan bahan bakar minyak ataupun gas dalam keperluan rumah tangga. Bahan bakunya diambil dari bahan yang mudah didapat dan sudah tidak dapat dipakai lagi, tetapi dapat di recycle menjadi biogas yang sangat bermanfaat bagi masyarakat. Dalam industri tempe yang berkembang di masyarakat terdapat limbah cair yang biasanya tidak dimanfaatkan dan dibuang begitu saja dilingkungan yang kemudian dapat mengakibatkan pencemaran terhadap lingkungan. Padahal sebagian besar kandungan dalam limbah cair tempe dapat dimanfaatkan menjadi biogas. Kelurahan Habaring Hurung, memiliki sebuah industry rumah tangga pembuatan tempe yang menghasilkan limbah cair dengan kuantitas yang cukup berlimpah, maka berpotensi sebagai penghasil biogas. Pelatihan pembuatan biogas di kelurahan Habaring Hurung, Kecamatan Bukit Batu, Kota Palangka Raya, ini bertujuan memberikan bekal kepada masyarakat, tentang pemanfaatan limbah cair tempe menjadi biogas. Tujuan dari pengabdian kepada masyarakat ini adalah memberikan gambaran berupa metode pembuatan biogas, bahannya yang berasal dari limbah cair tempe, sehingga dapat dimanfaatkan sebagai alternatif bahan bakar. Metode pelaksanaan terbagi dalam beberapa tahapan diantaranya persiapan yang meliputi menerbitkan surat tugas dan identifikasi masalah, wawancara yang meliputi survei kondisi lingkungan dan pemaparan rencana kepada mitra, perakitan reactor yang meliputi pengumpulan alat dan perakitan biogas digester, diakhiri dengan penyerahan biogas digester kepada pemilik industri tempe. Hasil yang dicapai dari kegiatan ini adalah warga masyarakat Kelurahan Habaring Hurung semakin memiliki wawasan yang terbuka untuk mengolah limbah cair tempe menjadi biogas, sehingga keberadaan limbah cair tempe yang awalnya mencemari lingkungan sekitar industri saat ini menjadi sebuah potensi energi terbaharukan yang mudah untuk dikembangkan.
Aktivitas antioksidan dan uji sitotoksik infusa daun jarak pagar (Jatropha curcas) Sudarman Rahman; Alayya Adistia Putri; Erwin Prasetya Toepak; Stevin Carolius Angga; Ysrafil Ysrafil
Sasambo Journal of Pharmacy Vol. 4 No. 2 (2023): September
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/sjp.v4i2.232

Abstract

Antioxidants are crucial in preventing cell damage caused by oxidation from oxidants. The use of antioxidants from natural products such as Jatropha curcas leaves can counteract free radicals due to the presence of secondary metabolites. The main aims of the study were to determine the antioxidant and cytotoxic activity of the infusion of J. curcas leaves. The sample was extracted using the infusion method. A qualitative phytochemical screening was carried out using the test tube method, antioxidant assay using the DPPH method and cytotoxic using the BSLT method. The results showed that the infuse of J. curcas leaves contained secondary metabolites such as polyphenols and tannins, alkaloids, flavonoids, and saponins. In the antioxidant activity test, infuse of J. curcas leaves and vitamin C (control) the IC50 was 58.90±2.34 ppm and 8.78±0.21 ppm respectively. The infused cytotoxic test contained an active toxic compound in shrimp larvae with an LC50 of 200.28 ppm (LC50 ≤ 1000 ppm). Based on the results of the study, infuse of J. curcas leaves showed potential as an antioxidant and anticancer agent with a strong classification.