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All Journal JMM (Jurnal Masyarakat Mandiri) Logista: Jurnal Ilmiah Pengabdian Kepada Masyarakat Journal of Appropriate Technology for Community Services Eduproxima : Jurnal Ilmiah Pendidikan IPA Jurnal Mandala Pengabdian Masyarakat Jurnal SAGO Gizi dan Kesehatan Jurnal Farmasi dan Sains Indonesia (JFSI) Sasambo Journal of Pharmacy INDRA: Jurnal Pengabdian kepada Masyarakat Jurnal Pengabdian Masyarakat Ilmu Terapan (JPMIT) Jurnal Ilmiah Berkala: Sains dan Terapan Kimia Nanggroe: Journal Of Scholarly Service Jurnal Ilmiah Kesehatan Lansau: Jurnal Ilmu Kefarmasian Nanggroe: Journal of Scholarly Service
Rahman, Sudarman
Universitas Palangka Raya
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Electrical & Electronics Engineering Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Mechanical Engineering Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Other

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Journal : Sasambo Journal of Pharmacy

 1 
Profil fitokimia dan aktivitas antibakteri fraksi etil asetat akar jarak pagar (Jatropha curcas Linn.) Sudarman Rahman; Stevin Carolius Angga; Erwin Prasetya Toepak; Muhammad Takdir Bachtiar
Sasambo Journal of Pharmacy Vol. 2 No. 2 (2021): September
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (383.8 KB) | DOI: 10.29303/sjp.v2i2.116

Abstract

Bacterial infections are a major cause of chronic infections and mortality that continues to threaten public health worldwide. Various medicinal plants used in folk medicine have demonstrated wound healing and antibacterial properties. The aims of the study are investigation phytochemical and antibacterial activity of ethyl acetate fraction from jarak pagar roots (Jatropha curcas Linn.). The roots were treated with maceration method using ethanol 70% and subsequently fractioned to ethyl acetate fraction. The fractions were used for phytochemical screening and antibacterial assay using Kirby and Bauer agar difussion method. The results showed that ethyl acetate fraction jarak pagar roots contained alkaloid, flavonoids, saponins, steroids, poliphenol dan tannins. The antibacterial activity of jarak pagar roots againts Staphylococcus aureus and Escherichia coli shows that the activity of this fraction with concentration 8 mg/mL has strong inhibitory potency against the growth S. aureus with inhibitory zone is 14,3 mm and has moderate inhibitory potency against E. coli with inhibitory zone is 9 mm. The increase concentrations of ethyl asetate fraction jarak pagar roots shows high inhibition diameter of bacterial growth.  
Aktivitas antioksidan dan uji sitotoksik infusa daun jarak pagar (Jatropha curcas) Sudarman Rahman; Alayya Adistia Putri; Erwin Prasetya Toepak; Stevin Carolius Angga; Ysrafil Ysrafil
Sasambo Journal of Pharmacy Vol. 4 No. 2 (2023): September
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/sjp.v4i2.232

Abstract

Antioxidants are crucial in preventing cell damage caused by oxidation from oxidants. The use of antioxidants from natural products such as Jatropha curcas leaves can counteract free radicals due to the presence of secondary metabolites. The main aims of the study were to determine the antioxidant and cytotoxic activity of the infusion of J. curcas leaves. The sample was extracted using the infusion method. A qualitative phytochemical screening was carried out using the test tube method, antioxidant assay using the DPPH method and cytotoxic using the BSLT method. The results showed that the infuse of J. curcas leaves contained secondary metabolites such as polyphenols and tannins, alkaloids, flavonoids, and saponins. In the antioxidant activity test, infuse of J. curcas leaves and vitamin C (control) the IC50 was 58.90±2.34 ppm and 8.78±0.21 ppm respectively. The infused cytotoxic test contained an active toxic compound in shrimp larvae with an LC50 of 200.28 ppm (LC50 ≤ 1000 ppm). Based on the results of the study, infuse of J. curcas leaves showed potential as an antioxidant and anticancer agent with a strong classification.
Co-Authors Agus Lasono Alayya Adistia Putri Alfanaar, Rokiy Arfan Arfan Atilla Dian Dewanti Gintoro Desimaria Panjaitan Dita Monita Erwin Prasetya Toepak Erwin Prasetya Toepak Erwin Prasetya Toepak Erwin Prasetya Toepak Erwin Prasetya Toepak Fatiqin, Awalul Febri Nur Ngazizah Ferry Patrix I Nyoman, Sudyana, Idin Sahidin Ika Oktavia Wulandari Karyadi Karyadi Mistryani, Mistryani Muafa Purwa Arsana Muhammad Takdir Bachtiar Mu’afa Purwa Arsana Mu’afa Purwa Arsana Ruslin Ruslin Sabarudin Sabarudin Sahidin Sahidin Sahumena, Muhamad Handoyo Sandi Mahesa Yudhantara Sari Namarito Simamarta Sari Namarito Simarmata Sari, Meiyanti Ratna Kumala Shesanti Citra Riana Shesanti Citra Riana Stevin Carolius Angga Thathit Suprayogi Thatit Suprayogi Yahya Febrianto Yohanes Edi Gunawan Ysrafil Ysrafil Ysrafil Ysrafil Yudhi Ekakristian Sahari Zahrotun Nafisah Zimon Pereiz