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All Journal Jurnal Penelitian Kesehatan AcTion: Aceh Nutrition Journal Dinamika Governance : Jurnal Ilmu Administrasi Negara JURNAL MUTIARA KESEHATAN MASYARAKAT JURNAL MUTIARA NERS Jurnal Kesehatan Masyarakat dan Lingkungan Hidup JURNAL ONLINE KEPERAWATAN INDONESIA Jurnal Ilmiah PANNMED (Pharmacist, Analyst, Nurse, Nutrition, Midwivery, Environment, Dentist) Science Midwifery Jurnal SAGO Gizi dan Kesehatan Jurnal Kesehatan Gigi (Dental Health Journal) Aloha International Journal of Multidisciplinary Advancement (AIJMU) DHeJA JEUMPA Jurnal PADE: Pengabdian & Edukasi Nasuwakes : Jurnal Kesehatan Ilmiah Buletin Pengabdian
Cut Aja Nuraskin
Jurusan Kesehatan Gigi, Poltekkes Kemenkes Aceh, Aceh
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Journal : Science Midwifery

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Methanolic Extract From Cocoa Bean (Theobroma Cacao L.) As A Potential Active Ingredient In Mouthwash Ainun Mardiah; Cut Aja Nuraskin
Science Midwifery Vol 10 No 3 (2022): August: Science Midwifery
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v10i3.638

Abstract

Dental plaque is a soft deposit firmly attached to the surface of teeth, formed from a mixture of saliva; such as mucin, remnants of oral tissue cells, leukocytes, lymphocytes with food debris, and bacteria resulting in the initial occurrence of tooth decay due to reduced pH. Unfortunately, currently available antiseptics-based mouthwash, used to prevent dental plaque formation, is thought to have a carcinogenic effect. Therefore, an alternative plaque was proposed using herbal antibacterial agents. Cocoa beans have anti-bacterial properties and are known to have active anti-bacterial agents, these substances are flavonoids, phenolics, alkaloids, terpenoids, saponins, and tannins. Herein, we aimed to determine the phytochemical content of methanol extract from cocoa bean (Theobroma cacao L.) and its antibacterial activities against Streptococcus mutans and subsequently studied its potential as a mouthwash active ingredient. Macerated methanolic extract of cocoa bean was investigated against clinical isolates of S. mutans. Qualitative phytochemical tests were further performed to observe the presence of flavonoids, phenolics, alkaloids, terpenoids, saponins, and tannins. The results showed that the growth of S. mutans colonies at a concentration of 1, 2, and 3% were 431×104, 142×104, and 59.5×104 CFU/mL, respectively. Addition of the extract at all concentrations (1—3%) did not affect the color, aroma, taste, and clarity of the mouthwash. An acute toxicity test on mice model confirmed that the cocoa bean-based mouthwash was safe.
Co-Authors Ainun Mardhiah Ainun Mardiah Ainun Mardiah Amiruddin Amiruddin Andriani Andriani Andriani Aripin Ahmad, Aripin Citra F Putri Citra Feriana Putri Cut Fazlil Hanum Eka Sri Rahayu Eka Sri Rahayu Eka Srirahayu Elfi Zahara Elfi Zahara erlinawati erlinawati Faradhilla Faradhilla Hamsar, Adriana Heru Santoso Wahito Nugroho Intan Dwi Addilla Intan Liana Intan Liana Julia Maulana Lina Farsia Lisa Hanum M Mufizarni Marzuki Mufizarni Mufizarni Mufizarni Mufizarni Mufizarni Munira Munira Niakurniawati, Niakurniawati Nurdin Nurdin Nurhaida R Reca Raihan Nabila Ratna Wilis Ratna Wilis Reca Reca Reca Reca Reca Reca Reca Reca Reca Reca Reca Reca Reca Reca Reca Reca Reca Reca Reca, Reca Rita Zahara Rosma, Manta Rosmini Rosmini Sisca Mardelita Sisca Mardelita T. Iskandar Faisal Teuku Salfiyadi Teuku Salfiyadi Teuku Salfiyadi Teuku Salfiyadi Salfiyadi Wirza Wirza Yeni Rimadeni