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All Journal Indonesian Journal of Pharmaceutical Science and Technology Jurnal Fitofarmaka Indonesia Jurnal Penelitian Pendidikan IPA (JPPIPA) Media Farmasi Media Kesehatan Politeknik Kesehatan Makassar PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Journal of Pharmaceutical and Medicinal Sciences ad-Dawaa : Journal of Pharmaceutical Sciences Jurnal farmasi UIN Alauddin Makassar Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan
Maulita Indrisari, Maulita
Sekolah Tinggi Ilmu Farmasi Makassar
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Education Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Physics Public Health

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Journal : Jurnal Fitofarmaka Indonesia

 1 
Efek Pemberian Ekstrak Etanol Daun Sembukan (Paederia foetida L.) Terhadap Penurunan Kadar Asam Urat Tikus Putih (Rattus norvegicus) Jantan mus, suwahyuni; Indrisari, Maulita; Maryam, Fadhillah; Surida, Surida
Jurnal Fitofarmaka Indonesia Vol 9, No 1 (2022): JURNAL FITOFARMAKA INDONESIA
Publisher : Jurnal Fitofarmaka Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jffi.v9i1.801

Abstract

Sembukan leaf is a medicinal plant that is widely used by the community, one of which is as an anti-inflammatory. This study aims to determine the effect of giving sembukan leaves (Paederia foetida L.) to decrease uric acid levels in male white rats (Rattus norvegicus). The study was carried out by testing 5 groups of white rats, namely positive control (Allopurinol 100 mg), negative control (Na.CMC suspension 0.5%), the dose of ethanol extract of sembukan leaves 10 mg/KgBB, 20 mg/KgBB, and 40 mg/KgBB. Each treatment group was measured initial uric acid levels (before induction), after induction of chicken liver juice and after giving treatment or test samples using test strips. The results showed that uric acid levels in all groups decreased with the percentage decrease in uric acid levels at a dose of 10 mg/Kg BB, 20 mg/Kg BB and 40 mg/Kg BB, respectively by 13.2%, 24.5% and 54.3%. The results of the One Way Anova statistical test showed a significant difference with P value = 0.010 (α <0.05). The concentration of the extract that gave the greatest reducing effect was the extract dose of 40mg/kgBB. 
Efek Pemberian Ekstrak Etanol Daun Sembukan (Paederia foetida L.) Terhadap Penurunan Kadar Asam Urat Tikus Putih (Rattus norvegicus) Jantan Suwahyuni Mus; Maulita Indrisari; Fadhillah Maryam; Surida Surida
Jurnal Fitofarmaka Indonesia Vol 9, No 1 (2022): JURNAL FITOFARMAKA INDONESIA
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jffi.v9i1.809

Abstract

Sembukan leaf is a medicinal plant that is widely used by the community, one of which is as an anti-inflammatory. This study aims to determine the effect of giving sembukan leaves (Paederia foetida L.) to decrease uric acid levels in male white rats (Rattus norvegicus). The study was carried out by testing 5 groups of white rats, namely positive control (Allopurinol 100 mg), negative control (Na.CMC suspension 0.5%), the dose of ethanol extract of sembukan leaves 10 mg/KgBB, 20 mg/KgBB, and 40 mg/KgBB. Each treatment group measured initial uric acid levels (before induction), after induction of chicken liver juice and after giving treatment or test samples using test strips. The results showed that uric acid levels in all groups decreased with the percentage decrease in uric acid levels at a dose of 10 mg/Kg BB, 20 mg/Kg BB and 40 mg/Kg BB, respectively by 13.2%, 24.5% and 54.3%. The results of the One Way Anova statistical test showed a significant difference with P value = 0.010 (α <0.05). The concentration of the extract that gave the greatest reducing effect was the extract dose of 40mg/kgBB.
Co-Authors Abd Halim Umar Abdul Halim Umar Ade Irma Sari Ade Putri Allyah Agustina Ma'tang Parinding Akbar Awaluddin Amriani Amriani Amriani Sapra Andi Nur Aisyah Andi Nur Aisyah Arisah Arisah Asril Burhan Astuti Amin Fadhillah Maryam Fitriyanti Jumaetri Habibie Habibie Ikbal Ikbal Ismah Mahmud Lukman Lukman Lukman Muslimin Madinatul munawwarah Margaretha Margaretha Marliana Pasang Marliana Pasang, Marliana Marwati Marwati Marwati Marwati Maryam, Fadhillah Megawati Megawati Michrun Nisa Mus, Suwahyuni Noer Fauziah Nur Khairi Nur Khairi Nurhikma Awaluddin Nursamsiar Nursamsiar Nursamsiar Nursamsiar Saldi Hapiwaty Sitti Rahimah Sitti Rahimah St. Rahimah Surida Surida Surida, Surida Suwahyuni Mus Syamsu Nur Wahyu Hendrarti Wahyu Hendrarti Wahyu Hendrarti Zulham Zulham