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All Journal Proceeding SENDI_U Biomedical Journal of Indonesia SRIWIJAYA JOURNAL OF MEDICINE Jurnal Kesehatan YARSI Medical Journal
Sri Nita, Sri
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Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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EFFECT OF HIBISCUS ROSA-SINENSIS LINN. EXTRACTS ON THE AMOUNT, MOTILITY, MORPHOLOGY, VABILITY OF SPERMATOZOA OF MALE RATS (RATTUS NORVEGICUS) Julia, Dina; Salni, salni; Nita, Sri
Biomedical Journal of Indonesia Vol 5, No 1 (2019)
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v5i1.7976

Abstract

The participation of men in family planning is still relatively low when compared to the participation of women. One of the traditional medicinal plants used is antifertility hibiscus flowers. This study aims to examine the effect of hibiscus flower extract on the number, motility, morphology and viability of spermatozoa of male rats (Rattus norvegicus). This research is an experimental study using a completely randomized design (CRD). The sample in this study used 25 male Sprague Dawley strains aged 60-70 days with a body weight of 200-210 grams. Duration of treatment for 30 days at a dose of 200 mg / kg, 300 mg / kg, 400 mg / kg. Data is presented in the form of tables and diagrams and narration to interpret the data. The results of this study indicate a decrease in sperm count in the treatment group compared to the control group (p = 0,000), a decrease in sperm motility (p = 0.001), an abnormal morphological increase (p = 0,000), and a decrease in spermatozoa viability between the treatment groups compared to the group control (p = 0,000). It can be concluded that there is a significant difference in the effect of hibiscus flower extract on the number, motility, morphology, viability of spermatozoa.
EFFECT OF HIBISCUS FLOWERS (HIBISCUS ROSA-SINENSIS LINN.) ON EPIDIDYMIS, PROSTATE AND SEMINAL VESICLES Carolin, Bunga Tiara; Salni, Salni; Nita, Sri
Biomedical Journal of Indonesia Vol 5, No 1 (2019)
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v5i1.7972

Abstract

Hibiscus rosa-sinensis Linn. is one of the medicinal plants in Indonesia which is used as male contraception. Hibiscus flowers contain flavonoids which can reduce testosterone. The purpose of this study was to determine the effect of hibiscus flower extract on epididymal weight, cauda epididymal epithelial thickness, prostate weight and seminal vesicle of male rats. This research is an experimental study using a completely randomized design (CRD). The sample in this study used 25 male Sprague Dawley® strains aged 60-70 days with a body weight of 200-210 grams. The treatment dose is 200 mg / kg, 300 mg / kg, 400 mg / kg, 500 mg / kg for 30 days. The data is presented in tabular form and narrative to interpret the data. The results showed a decrease in epididymal weight in the treatment group compared to the control group (p = 0,000), there was also a thick shrinkage of the cauda epididymal epithelium (p = 0.021), a decrease in prostate weight and seminal vesicles between the treatment group versus the control group (p = 0.001). It can be concluded that there is an effect of hibiscus flower extract on the epididymis, prostate and seminal vesicles. The influence is likely due to the chemical content that is in hibiscus flowers that are antifertility.
Co-Authors Andriani Andriani AR, Djunaidi Carolin, Bunga Tiara Fitri Adona Hayati, Lusiya Hayati, Lusiya Julia, Dina Julia, Dina Louis, Stephanie Lexy Mafrudoh, Luth Muhammad Irsan Saleh RACHMAT HIDAYAT Rahman, Ahadi Aulia Rahman, Ahadi Aulia Rasasta, Meida Robiatul Adawiyah Salni Setawan, Arum Subandrate Tursia, Anita Vinnata, Nora Novia Yusnani Yusnani