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Journal : Jurnal Surya Medika

Uji Aktivitas Analgetik Ekstrak Batang Karamunting (Rhodomyrtus tomentosa) terhadap Tikus Jantan Galur Wistar Rika Arfiana Safitri; Mamik Ponco Rahayu; Gunawan Pamudji Widodo
Jurnal Surya Medika (JSM) Vol 7 No 2 (2022): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v7i2.3216

Abstract

Pain is only a symptom and a mechanism in the body that serves as a danger signal about a disturbance in the tissue such as inflammation, infection, or muscle spasms. This study aims to determine the effect of the analgesic effect of the ethanol extract of the karamunting stem. Karamunting stems were extracted by the maceration method using 96% ethanol as solvent. Each analgesic test was divided into five groups, namely a negative control group (CMC Na), a positive control group (Tramadol), a karamunting stem extract test group (a dose of 100 mg/kg BW, 200 mg/Kg BW, and 400 mg/Kg BB). Analgesic test using Tail flick method. Data analysis used the Shapiro-Wilk test and then continued with the one-way ANOVA test. The results showed that the ethanol extract of the karamunting stem could provide an analgesic effect at a dose of 200 mg/Kg BW.
Uji Aktivitas Antiinflamasi Ekstrak Batang Karamunting (Rhodomyrtus tomentosa) Terhadap Tikus Jantan Galur Wistar: Test of Antiinflamatory Activity Extract of Karamunting (Rhodomyrtus tomentosa) Stem to Male Rat Wistar Strain Rika Arfiana Safitri; Mamik Ponco Rahayu; Gunawan Pamudji Widodo
Jurnal Surya Medika (JSM) Vol. 9 No. 1 (2023): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v9i1.5202

Abstract

Inflammation is a response to tissue damage due to various adverse stimuli, both chemical and mechanical, infections and foreign bodies such as bacteria and viruses. This study aims to determine the effect of the anti-inflammatory effect of ethanol extract of karamunting stems. Karamunting stems were extracted by maceration method using 96% ethanol solvent. Each anti-inflamatory test was divided into five groups, namely the negative control group (CMC Na), the positive control group (Diclofenac Na), the Karamunting stem extract test group (dose of 100 mg/kg BW, 200 mg/Kg BW, and 400 mg/kg). kg BW). Anti-inflammatory test using the Rat hind paw edema method induced by 1% carrageenan. Data analysis used the Shapiro-Wilk test and then continued with a one-way ANOVA test. The results showed that the ethanol extract of karamunting stems had an anti-inflammatory effect at doses of 200 mg/Kg BW and 400 mg/Kg BW.the karamunting stem could provide an analgesic effect at a dose of 200 mg/Kg BW.