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Jurnal Kesehatan Islam : Islamic Health Journal
Published by Universitas Islam Malang
ISSN : 2303022X     EISSN : 26158345     DOI : -
Core Subject : Health, Science, Agriculture, Social,
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Environmental Science Medicine & Pharmacology Public Health
Jurnal Riset Kedokteran Islam berisi informasi tentang hasil kegiatan penelitian, pemikiran konseptual dan kajian bidang ilmu kedokteran dan kedokteran. Jurnal ilmiah ini diterbitkan oleh Fakultas Kedokteran Universitas Islam Malang. Jurnal ini diterbitkan dengan frekuensi 2 kali setahun, yaitu pada bulan Maret dan bulan September.
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Articles 11 Documents
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Search results for , issue "Vol. 11 No. 2 (2022): Jurnal Kesehatan Islam : Islamic Health Journal" : 11 Documents clear
Analisis Efektivitas Biaya Terapi Antihipertensi pada Pasien Rawat Inap Covid-19 dengan Hipertensi di RSUD Panembahan Senopati Bantul Yogyakarta Fitri Andriani Fatimah; Anis Febri Nilansari; Rahmat A Hi Wahid
Jurnal Kesehatan Islam : Islamic Health Journal Vol. 11 No. 2 (2022): Jurnal Kesehatan Islam : Islamic Health Journal
Publisher : Publikasi oleh Fakultas Kedokteran Universitas Islam Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33474/jki.v11i2.19224

Abstract

Abstract. Hypertension is the highest comorbid group of Covid-19patients, which is 50.5%, followed by diabetes mellitus 34.5% and heart disease 19.6%. Most hypertensive patients have blood pressure that is not controlled with single therapy, while the cost of treatment is increasing every year. The presence of comorbid hypertension in Covid19 patients has an impact on increasing costs, with the highest average cost being in pharmaceutical costs. This needs to be analyzed to find out which antihypertensive drugs are the most cost-effective and provide the best therapeutic outcomes, especially during the Covid-19pandemic. The purpose of this study was to determine the most costeffective antihypertensive therapy in hypertensive patients with Covid19 in 2020-2022 at Panembahan Senopati Hospital, Bantul, Yogyakarta. This study uses a non-experimental research method that is descriptive analytic. Data was collected retrospectively based on medical records, laboratory results and drug price ceilings in the hospital administration. Cost-effectiveness analysis was carried out by comparing the average direct medical cost to the percentage of patients whose blood pressure reached the target based on ACER parameters and was declared cured (the results of the swab-test or PCR examination were declared negative). The results of the study on 63 Covid-19 patients with hypertension showed that the most costeffective antihypertensive drug class for hypertension monotherapy was the CCB group, the most cost-effective combination of 2 antihypertensive therapies was the ARB and Diuretics and the 3 most costeffective combination of antihypertensive drug classes. effective is a combination of BB, ACEI and diuretics.
Efek Pemberian Ekstrak Etanol Daun Jarak Merah (Jatropha gossypiifolia L.) terhadap Kadar Glukosa Darah Puasa, Kadar Insulin Serum dan HOMAIR pada Model Tikus DM Tipe 2 Nugroho Wibisono; Achmad Basori; Suhartati
Jurnal Kesehatan Islam : Islamic Health Journal Vol. 11 No. 2 (2022): Jurnal Kesehatan Islam : Islamic Health Journal
Publisher : Publikasi oleh Fakultas Kedokteran Universitas Islam Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33474/jki.v11i2.19225

Abstract

Abstract. Jatropha gossypiifolia L. is a medicinal plant from theEuphorbiaceae family. Jatropha gossypiifolia L. leaves have somemedicinal properties, but their effect on antidiabetics mechanisms isstill unclear. Jatropha gossypiifolia leaves have some activecompounds such as alkaloid, flavonoid, phenol, saponins, tannins,steroid, terpenoid, and triterpenoid. The presentstudy was designedto analyze effect of Jatropha gossypiifolia leaves extract activecompounds on fasting blood glucose levels, serum insulin levels andHOMA-IR. The design of thisresearch istrue experimental with posttest only control group design with independent variables includinga high-fat diet, streptozotocin injections, Jatropha gossypiifolia L.leaves extract in doses of 60, 120, dan 240 mg/kg and dependentvariables including fasting blood glucose levels, serum insulin levels,and HOMA-IR. Based on this study, there were a significantlydifferent between fasting blood glucose levels and HOMA-IR controlgroups than the extract groups. It can be concluded that Jatrophagossypiifolia L. leaves extract has effect on fasting blood glucoselevels, serum insulin levels and HOMA-IR on DM type 2 rat models.
Hubungan Kualitas Tidur Remaja Selama Pandemi Covid-19 dengan Aktivitas Fisik Serta Screen-Time Arwan Bin Laeto; Siti Sarahdeaz Fazzaura Putri; Eka Febri Zulissetiana; Swanny
Jurnal Kesehatan Islam : Islamic Health Journal Vol. 11 No. 2 (2022): Jurnal Kesehatan Islam : Islamic Health Journal
Publisher : Publikasi oleh Fakultas Kedokteran Universitas Islam Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33474/jki.v11i2.19226

Abstract

Abstract. Public health is an aspect that has shown a decline sincethe COVID-19 pandemic emerged, both globally and in Indonesia.Seeing these conditions, the Indonesian government has implemented restrictions on community mobility, including the learning process (lectures) which must be held online. This triggers an increasein screen time among teenagers, while at the same time there is adecrease in sleep quality and low physical activity. The purpose ofthis study was to determine the relationship between sleep qualityduring the COVID-19 pandemic with the level of physical activity andthe degree of screen time for adolescents. The objection of thisresearch is to analyze the relationship between adolescent sleepquality during the Covid-19 pandemic with levels of physical activityand screen-time. Methods: The study used an observationalapproach with a crosssectional design of 185 students. The researchwas conducted in November 2021 at the Faculty of Medicine,Sriwijaya University. Research data collection through onlinequestionnaires and data analysis using Chi square test. Results: Thisstudy shows the results, as many as 77.82% of students have poorsleep quality, 48.64% have low levels of physical activity and 76.22%of students show high smartphone screen-time. The bivariate testshowed that there was a significant relationship between the levelof physical activity and sleep quality, namely p = 0.002. However,there was no significant relationship between sleep quality and thedegree of screen-time (p = 0.253). Conclusion: The level of physicalactivity has a significant relationship with adolescent sleep quality.Physical activity is a factor that affects teenagers in getting goodquality sleep during the COVID-19 pandemic.
Serum Calcium Levels in Stunting Toddlers Ages 24-59 Months Bayu Anggriani; Rico Januar Sitorus; Rostika Flora; Risnawati Tanjung
Jurnal Kesehatan Islam : Islamic Health Journal Vol. 11 No. 2 (2022): Jurnal Kesehatan Islam : Islamic Health Journal
Publisher : Publikasi oleh Fakultas Kedokteran Universitas Islam Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33474/jki.v11i2.19227

Abstract

Abstract. Stunting is a condition of failure to thrive in children under five due to chronic malnutrition, especially in the First 1,000 Days of Life (DoL). Malnutrition that occurs early in life can lead to failure to thrive, resulting in a shorter than normal child. Good quality food intake is an important component in children's growth, because it contains sources of macro (energy, carbohydrates, protein, fat) and micro (vitamins and minerals) nutrients. Micronutrients that have been proven to be very important to prevent stunting are zinc, iron, vitamin A and iodine. However, several other micronutrients such as vitamin D, calcium and phosphorus also play an important role in children's linear growth. the special function of vitamin D in this case is to help harden bones by regulating so that calcium and phosphorus are available in the blood to be deposited in the process of bone hardening. During growth, the process of bone mineralization often occurs, calcium deficiency will affect linear growth if the calcium content in the bone is less than 50% of the normal content. Lack of calcium in the bones in infants can cause rickets, whereas in children, lack of deposits can cause stunted growth. This research is an observational analytic study with a cross sectional design conducted in Mestong District, Muaro Jambi Regency in March 2022. The research sample was normal and stunted toddlers aged 24- 59 months as many as 41 people taken using proportional consecutive sampling technique. Examination of serum calcium levels was carried out on toddlers using the Calcium (Ca) Colorimetric Assay Kit method. The results showed that there was no difference in serum calcium levels in normal and stunted children
The Role of Syzygium Polyanthum Leaf Extract in Reducing Renal Cell Damage with Potassium Oxonate-Induced Hyperuricemia Dwimantoro; Hotimah Masdan Salim; Aditya Bhayusakti; Dayu Satriya Wibawa
Jurnal Kesehatan Islam : Islamic Health Journal Vol. 11 No. 2 (2022): Jurnal Kesehatan Islam : Islamic Health Journal
Publisher : Publikasi oleh Fakultas Kedokteran Universitas Islam Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33474/jki.v11i2.19229

Abstract

Abstract. Background: Kidney is an organ that plays an important rolein regulating homeostasis, excrete the foreign or toxic substances, andmetabolism product such as uric acid, urea, and creatinine in the bodythrough the urine. Syzygium polyanthum, has been used in loweringuric acid levels. The purpose of this research is to tested the effect ofbay leaf extract on kidney histopathology of hyperuricemia inducedmice model of potassium oxonate. Methods: This study is a laboratoryexperimentalstudy with a post-test only control group design, and wasdivided into a control group, a hyperuricemia (PO) group, an PO groupwith 75 mg/kg bay leaf extract, an PO group with 150 bay leaf extractand an PO group with 300 mg/kgBW bay leaf extract. The treatmentwas given for 14 days then histopathological examination of thekidneys was carried out with HE staining. Results: Histopathologicalinflammation occurred in all groups and necrosis was the most severefound in the positive control group where the administration of bayleaf extractsignificantly reduced inflammatory cellsfrom the lowest tothe highest dose with P < 0.001. Conclusion: Administration ofSyzygium polyanthum affected renal histopathology in potassiumoxonate-induced hyperuricemic mice.
Pengetahuan dan Dukungan Keluarga terhadap Kepatuhan Penggunaan OAT di Dua Puskesmas di Kabupaten Lombok Utara Rizka Novia Atmadani; Utari Dita Fitriana; Mutiara Titani
Jurnal Kesehatan Islam : Islamic Health Journal Vol. 11 No. 2 (2022): Jurnal Kesehatan Islam : Islamic Health Journal
Publisher : Publikasi oleh Fakultas Kedokteran Universitas Islam Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33474/jki.v11i2.19230

Abstract

Abstract. Tuberculosis (TB) is a disease that is transmitted by the bacterium Mycobacterium tuberculosis. Adherence in pulmonary TB treatment is important so that patients can recovery. According to Lawrenve Green’s theory, factors that influence patient compliance behavior in taking medication are predisposing, enabling, and rein- forcing factors. Research Methods: The research design used is des- criptive correlative using a cross sectional approach. This research was conducted in August 2022, the samples were 40 patients with pulmo- nary TB who were treated at the Gangga Health Care and Tanjung Health Care, North Lombok Regency with accidental sampling tech- nique. The research instrument used in this study was a questionnaire and analyzed by Chi-Square test using software SPPS version 24.The results of the validity and reliability tests have met the requirements Result and Discussion: Patients who have good knowledge of 95.0%, 5.0% good knowledge, and family support of 87.5 % good knowledge, 12.5% poor knowledge. Patients with good knowledge were found to have 85.0% adherence to the use of OAT. The results from bivariate analysis, the level of knowledge P-value = 0.019 < α = 0.05, and family support P-value = 0.018 < α = 0.05 Conclusion There is relationship between the level of knowledge with Tuberculosis patient adherence in taking OAT, and there is relationship between the level of family support with Tuberculosis patient adherence in taking OAT at the Gangga Health Center and Tanjung Health Center, North Lombok Regency.
Lama Bergadget Meningkatkan Resiko Adiksi Internet pada Anak Disabilitas Intelektual Shinta Kusumawati; Amelia Aziz Daeng Matadjo
Jurnal Kesehatan Islam : Islamic Health Journal Vol. 11 No. 2 (2022): Jurnal Kesehatan Islam : Islamic Health Journal
Publisher : Publikasi oleh Fakultas Kedokteran Universitas Islam Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33474/jki.v11i2.19231

Abstract

Abstract. Indonesia is one of the fourth largest smartphone usercountries in the world after China, India and the United States. Users ofsmartphones or gadgets are not only normal children and adolescentsbut also children and adolescents with disabilities. They use the interneteither as a medium of learning, entertainment or to fill theirspare time.This study aims to determine the level of internet addiction in childrenwith intellectual disabilities who use gadgets. Methods: The design wasa descriptive qualitative research with a cross sectional design. Theresearch data was taken using the Internet Addiction Test (IAT)questionnaire which was distributed via google form to the ABKcommunity in Malang City. The collected data were analyzed usinggamma correlation analysis. Results: the data of this study showed 8respondents consisting of 7 boys and 1 girl, with a long gadget per day2 hours (37.%%), and > 2 hours (62.5%). The level of internet addictionwas normal (37.5%), light (37.5%) and moderate (25%). The correlationof the length of time with the gadget per day on the level of addictionwas found to be p-value (0.739). Conclusion: There is no significantrelationship between length of time with gadgets per day with the levelof addiction in children with intellectual disabilities.
Kadar Zat Besi dengan Kejadian Stunting pada Balita di Kecamatan Mestong Kabupaten Muaro Jambi Susanti; Rostika Flora; Nur Alam Fajar; Mohammad Zulkarnain; Indah Yuliana
Jurnal Kesehatan Islam : Islamic Health Journal Vol. 11 No. 2 (2022): Jurnal Kesehatan Islam : Islamic Health Journal
Publisher : Publikasi oleh Fakultas Kedokteran Universitas Islam Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33474/jki.v11i2.19232

Abstract

Abstract. Gizi yang baik sebagai penentu kualitassumber daya manusiamerupakan salah satu hak anak yang berhubungan dengan pertumbuhan dan perkembangan. Salah satu zat gizi yang penting bagi pertumbuhan adalah zat besi yang merupakan microelement yang esensial bagi tubuh. Asupan zat besi yang kurang pada anak menyebabkanterhambatnya pertumbuhan pada anak sehingga jika berlangsungdalam waktu lama dapat menyebabkan stunting. Penelitian ini bertujuan untuk mengetahui hubungan kadar zat besi dengan kejadian stunting pada balita di Kecamatan Mestong. Penelitian ini bersifat analitikobservasional dengan pendekatan cross sectional,teknik pengambilansampel adalah consecutive sampling dimana sampel pada penelitianditemui saat penelitian sebanyak 61 respoden. Data yang diperolehselanjutnya, diolah dan dianalisis dengan menggunakan analisis univariat dan analisis bivariat menggunakan analisis chi-square yang bertujuan untuk mengetahui hubungan kadar zat besi dengan kejadianstunting pada balita di Kecamatan Mestong. Pemeriksaan kadar zatbesi dilakukan pada balita dengan metode Photometric Colorimetricdilakukan pada balita. Hasil penelitian menunjukkan Hasil uji statistikChi-Square Tests didapatkan nilai p = 0.384 (p > 0,05) yang menunjukkan bahwa tidak ada hubungan antara kadar zat besi dengan kejadianstunting pada balita di Kecamatan Mestong Kabupaten Muaro JambiProvinsi Jambi tahun 2022.
Pemberdayaan Pasien HIV dalam Kepatuhan Minum Obat ARV di Yayasan Cakap Peduli AIDS Turen Tri Nurhudi Sasono; Esti Yunitasari; Ninuk Dian Kurniawati; Nursalam
Jurnal Kesehatan Islam : Islamic Health Journal Vol. 11 No. 2 (2022): Jurnal Kesehatan Islam : Islamic Health Journal
Publisher : Publikasi oleh Fakultas Kedokteran Universitas Islam Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33474/jki.v11i2.19233

Abstract

Abstract. People with HIV-AIDS (PLWHA) are powerless in undergoing ARV treatment programs for the rest of their lives. Compliance with treatment of HIV patients in Indonesia is still a major problem, as evidenced by Lost Follow Up (LFU) for treatment and ART by 21.87%. This decrease in ART adherence ultimately makes patients susceptible to opportunistic infections and has a poor quality of life. The design of this research is pre-post test with control group. The approach used in this study is a non-equivalent control group. The sample used by the purposive sampling technique at the NGO CAKAP AIDS Turen was 48 respondents. Collecting data using a medication adherence question- naire. Statistical test using the Wilcoxon test. The results showed that there was an influence of empowerment with a p-value of 0.017 <0.05 with a coefficient of 0.309. Based on these statistical results, it can be concluded that the empowerment of HIV patients can affect medication adherence
Skrining Potensi Essential Oil Pogostemon Cablin Bent Secara In Silico dalam Penghambatannya terhadap ACE II dan TMPRSS2 sebagai Anti Covid-19 Yoni Rina Bintari; Dini Sri Damayanti
Jurnal Kesehatan Islam : Islamic Health Journal Vol. 11 No. 2 (2022): Jurnal Kesehatan Islam : Islamic Health Journal
Publisher : Publikasi oleh Fakultas Kedokteran Universitas Islam Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33474/jki.v11i2.19234

Abstract

Abstract. COVID-19 is a disease caused by a coronavirus class virusthatis known to enter humans by means of the Spike protein (S) binding toACEII (Angiotensin Coverting Enzyme) and then being activated byTMPRSS2 (Transmembrane Protease, Serine). COVID-19 has become apandemic, so it requires agents that act as anti-Covid-19. Pogostemoscablin bent is an herb that contains EO (Essential oil) and is widelygrown in Indonesia. EO is known to have potential as an antivirus. Thisstudy aims to predict the EO potential of P. Cablin as anticovid-19through a molecular docking approach by measuring its inhibition ofACE II (Q9BYF1) and TMPRSS2 (7MEQ). The inhibitory potential wascalculated from the binding affinity using Pyrex Autodock Vina software. The docking results are then visualized using Biovia DiscoveryStudio and PyMOL. Prediction of physicochemical and pharmacokineticprofiles through pKCsm web. The docking results showed that pachuolialcohol inhibited ACEII and TMPRSS2 with gibs energy of -7.7 kcal/mol,respectively, through the interaction of hydrogen His 383 and Asp 415and -5.8 kcal/mol through the interaction of hydrogen Leu 248. However, the mechanism of inhibition of pachuoli alcohol was different fromthat of chloroquine (Clq) and napamosphate. Clq inhibits ACE II throughthe amino acid residue Thr 282 with a gibs energy of -6.7 kcal/mol.Nafamosfat inhibits TMPRSS2 through amino acid residues Ser 333, Pro335, Tyr 337 with a gibs energy of -8.3 kcal/mol. Predictive results ofphytochemical screening and pharmacokinetic profiles indicate thatpachuoli alcohol is a potential drug candidate.

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