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Medical and Health Science Journal
Published by Universitas Nahdlatul Ulama Surabaya
ISSN : 25497588     EISSN : 25497596     DOI : https://doi.org/10.33086/mhsj
Core Subject : Health, Social,
Health Professions Social Sciences
Medical and Health Science (MHSJ) published peer-reviewed original articles research, case report or article review. This journal is published twice (February and August) by Faculty of Medicine Universitas Nahdlatul Ulama Surabaya.
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Articles 155 Documents
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GAMBARAN INDEKS LARVA AEDES AEGYPTI DI BUFFER WILAYAH KERJA BANDARA SEPINGGAN BALIKPAPAN Abdurrakhman, Abdurrakhman
Jurnal Ilmu Kesehatan dan Kesehatan Vol 3 No 1 (2019): February
Publisher : UNUSA Press

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The House index and Container Index in the buffer area of the working area of Balikpapan Sepinggan Airport is still above 1%, so the potential for the spread of dengue disease. Mobilization of people, goods and transportation equipment will increasingly affect the transmission of disease in ports and airports, especially for vector-borne diseases. This study aims to analyze the risk factors associated with larvae density of Aedes aegypti and describe the larvae index in the buffer zone of the Sepinggan Balikpapan Airport This study was a descriptive study with a cross sectional design. The sample in this study was 121 houses with a proportionate stratified random sampling, the research location was in the buffer zone of Sepinggan Balikpapan Airport in November 2018. The variables studied were houses with positive larvae containers, breeding sites and PSN behavior and larvasidation. The data was analyzed using the chi square test. There was a relationship between houses with larvae positive Aedes aegypti, behavior of Mosquito Nest Eradication (PSN) and larvasidation with larvae density of Aedes aegypti but not for breeding sites (p =0.00and95%CI=0.64),and (p=0.00and95%CI=0.34).Thedescription of several Aedes aegypti larvae index, namely House Index (HI) = 57.02%, Container Index (CI) = 24.36%, Bruteau Index (BI) = 148.76, and Flick Free Numbers (ABJ) = 42.98 %. Houses with larvae of Aedes aegypti larvae and PSN and larvasidation behavior were associated with larvae density of Aedes aegypti. The index of HI, CI and BI larvae is of high value so there is a risk of DBD transmission
THE RELATIONSHIP OF NUTRITIONAL STATUS TO URIC ACID LEVEL IN COMMUNITY OF PONDOK PESANTREN AL-HIDAYAH, NGAWI Lestari, Marselli Widya; Bintarti, Tri Wahyuni
Jurnal Ilmu Kesehatan dan Kesehatan Vol 3 No 1 (2019): February
Publisher : UNUSA Press

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Gout or Gouty Arthritis is a degenerative disease. Gouty arthritis is a clinical syndrome that is caused by deposition of purine crystals in the tissues, due to levels of uric acid (hyperuricemia) in the extracellular fluid that passes through saturation. The etiology of gout arthritis included age, sex, history of medication, obesity, consumption of purine and alcohol. Aging is an important risk factor for men and women. This study uses an analytical-descriptive approach with cross-sectional design. This study was conducted to obtain a relationship between nutritional status and uric acid levels in the community in the area of Al-Hidayah Islamic Boarding School, Ngawi. This research was conducted in Majasem Village, Kendal District, Ngawi Regency, starting from 7 June - 31 August 2018. The results showed that there was a relationship between nutritional status and uric acid levels in the community in the area of Al-Hidayah Islamic Boarding School, Ngawi (p=0,008). Suggestions for further research are bivariate analysis based on gender, knowledge and attitude to response to diet so that other factors that influence can be seen clearly.
IMUNOHISTOKIMIA PADA KONDILOMATA AKUMINATA Widyaswari, Meidyta Sinantryana; Lumintang, Hans; Soemarno, Troef
Jurnal Ilmu Kesehatan dan Kesehatan Vol 3 No 1 (2019): February
Publisher : UNUSA Press

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Background: Condylomata Acuminata (CA) is a sexually transmitted disease caused by the Human Papilloma Virus (HPV) type-specific and may be simultaneously co-infected with other HPV types associated with malignancy. Purpose: To differentiate between CA and histopathological of malignancy by immunohistochemistry. LiteratureReview: CA refers to benign epidermal proliferation caused by the HPV types 6 and 11, but co-infection with high- risk HPV types are common. The clinical presentation of CA can’t differentiate between benign or preneoplastik diplasia lesions. Koilocytes considered pathognomonic for HPV lesions, these findings sometimes don’t appear on CA, and histopathology was not accurate, that immunohistochemistry with MIB-1 (Ki-67) and p16 can beused. Conclusion: Immunohistochemistry examination can help differentiate the diagnosis between malignancy or non- malignancy in the case of CA.
CASE STUDY EFFECTIVNESS OF AMYODARON USE IN PATIENTS WITH SUPRAVENTRICULAR TACHYCARDIA AND HYPOTHYROIDISM Savitri, ,Ardyarini Dyah
Jurnal Ilmu Kesehatan dan Kesehatan Vol 3 No 1 (2019): February
Publisher : UNUSA Press

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A woman, 53 years of age, with recurrent supraventricular tachycardia (SVT) with hypothyroidism was thought to be associated with amiodarone use. Patients repeatedly get amiodarone for their arrhythmias, where amiodarone has a broad antiarrhythmic effect making it effective for the management of SVT. In addition, the low inotropic properties of amiodarone are low, making amiodarone the drug of choice in patients with heart failure. However, repeated use of amiodarone can cause many side effects, one of which is amiodarone induced hypothyroidism (AIH). Patients are given thyroxine hormone substitution therapy during the use of amiodarone and the response to the therapy given is quite good, so the patient has a good prognosis.
HUBUNGAN POLA MAKAN DAN KEBIASAAN OLAHRAGA YANG BAIK DENGAN KADAR GULA DARAH PENDERITA DIABETES MELLITUS TIPE II DI RSI JEMURSARI Rachmawati, Marlia Alief; ., Handayani; Donastin, Adyan
Jurnal Ilmu Kesehatan dan Kesehatan Vol 2 No 1 (2018): FEBRUARY
Publisher : UNUSA Press

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Abstrak: Diabetes Mellitus tipe II adalah penyakit kronis mengalami resistansi terhadap aksi insulindan ketidakmampuan pankreas untuk menghasilkan cukup insulin. DM tipe II sendiri mendudukiperingkat ke-2 di dunia dengan penderita terbanyak Pola makan yang buruk dan kurangnya olahragadapat memengaruhi terjadinya DM tipe II. Perkembangan pola makan yang salah arah saat inimempercepat peningkatan jumlah penderita DM di Indonesia. Pada saat tubuh melakukan gerakan,maka sejumlah gula akan dibakar untuk dijadikan tenaga gerak. Sehingga sejumlah gula dalamtubuh akan berkurang dan kebutuhan akan hormon insulin juga akan berkurang. Penelitian inibertujuan adalah untuk mengetahui hubungan pola makan dan kebiasaan olahraga dengan kadargula penderita Diabetes Mellitus II pada penderita Diabetes Mellitus II di RSI Jemursari Penelitianini dilakukan dengan metode survey atau observasional dengan pendekatan crosssectional. Sampelyang diambil sebanyak 24 pasien. Populasi dalam penelitian ini adalah semua pasien DiabetesMellitus Tipe 2 yang menjalani rawat jalan pada poli penyakit dalam, namun dibatasi dengankriteria inklusi dan eksklusi yang penulis buat. Dari 24 pasien, pada hubungan pola makan dengankadar gula darah sebanyak 13 pasien (54,2%) mempunyai kadar gula tidak tinggi. 11 pasien (45,8%)mempunyai kadar gula tinggi. Dengan hasil uji statistik didapatkan nilai p=1,000 (p>0,05). Makadapat disimpulkan bahwa terdapat hubungan yang tidak signifikan antara pola makan dan kadargula. Serta hubungan olahraga dengan kadar gula darah sebanyak 13 pasien (54,2%) mempunyaikadar gula tidak tinggi. 11 pasien (45,8%) mempunyai kadar gula tinggi. Dengan hasil uji statistikdidapatkan nilai p=0,432 (p>0,05). Maka dapat disimpulkan bahwa terdapat hubungan yang tidaksignifikan antara olahraga dan kadar gula.
PERBAIKAN FUNGSI TROFOBLAST PADA KADAR β hCG TIKUS BUNTING PREEKLAMPSIA PADA BAHAN BIOLOGIS TERSIMPAN PASCA PERLKUAN DENGAN SPIRULINA K, Gondo H; I, Noer Kumala; A, Adhiono ,
Jurnal Ilmu Kesehatan dan Kesehatan Vol 2 No 2 (2018): AUGUST
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v2i2.585

Abstract

Abstract: Preeclampsia is multisystem specific disorder in pregnancy. Preeclampsia has signed byincreased cytokine Interleukin-6 and ? hCG (human Chorionic Gonadotropin). Spirulina is green-bluealga has bioactive compound namely antioxidant, vitamin, mineral. And has benefit namelyantinflamation. The aim of this research was to know how spirulina influence to repair trophoblast inHcg concentration on rat pregnancy (biology material collecting). The type of this research is anexperimental laboratoric with post test only control group design. A total of 25 rats with pre-eclampsiamodels induced by Interleukin 6 are divided into 5 groups: the untreated control group, the positivecontrol group with Interleukin 6 induction for three days, the treatment group with a dose of 10 mg /day, 20 mg / day and 40 mg of spirulina. / day for five day, then the blood serum produced was measuredwith ? hCG levels using ELISA (Enzyme-Linked Immunosorbent Assay). The results of the Spirulina 10mg / day are higher at 85.11 ± 25.70 mIU / ml from a dose of spirulina 20 mg / day at 79.65 ± 10.65mIU / ml . In the level of ? hCG, the dose group of spirulina 10 mg / day and the group there is nosignificant difference (0.730> 0.05), the ? hCG level group of spirulina 40 mg / day was 93.28 ± 17, 12mIU / ml from the dose group of spirulina 10 mg / day was 85.11 ± 25.70 mIU / ml. The administrationof spirulina for five days was able to reduce ? hCG levels at a dose of 10 mg / day, 20 mg / day and 40mg / day and the dose that was most effective in reducing ? hCG levels significantly (P <0.05) was adose of 10 mg than dose of 20 mg / day and 40 mg / day.
EPILEPSI POST TRAUMA DENGAN GEJALA PSIKOTIK Irfana, Lailiy
Jurnal Ilmu Kesehatan dan Kesehatan Vol 2 No 2 (2018): AUGUST
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v2i2.589

Abstract

Abstrak: Data WHO menunjukkan epilepsi menyerang 1% penduduk dunia. Angka kejadian epilepsimasih tinggi terutama di negara berkembang yaitu mencapai 114 per 100.000 penduduk per tahun.2 Padakelompok dewasa muda, epilepsi dapat terjadi salah satunya disebabkan oleh trauma kepala.3 Kasus inimelaporkan penderita laki-laki usia 24 tahun dengan keluhan kejang yang disertai dengan gejala psikotik.Didapatkan riwayat pasien kejang pertama kali dua bulan setelah mengalami trauma kepala yaitu padatahun 2003. Saat itu pasien mengalami cedera otak berat dan dari CT scan kepala didapatkan perdarahandi otak. Dua bulan setelah trauma kepala itu pasien mengalami kejang berulang disertai keluhan yangdominan adalah marah-marah hingga pernah sampai mau membunuh orang. Dari analisis EEGmenunjukkan hasil epilepsi lobus frontotemporal. Setelah pasien mendapatkan pengobatan phenytoindan risperidone, kejang mulai terkontrol. Namun bila tidak minum obat pasien kejang lagi. Hal inidialami oleh pasien hingga saat kasus ini dilaporkan, yaitu sepuluh tahun post trauma.
GAMBARAN STATUS GIZI ANAK KELAS VI DI SEKOLAH DASAR MIFTAKHUL ULUM SURABAYA Herdiani, Novera; Afridah, Wiwik
Jurnal Ilmu Kesehatan dan Kesehatan Vol 2 No 1 (2018): FEBRUARY
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v2i1.609

Abstract

Abstract: Background, nutritional status is a description of balance between the need of nutrientsfor keeping a good life, to maintenance normal body function also energy production in one sideand the consumption of nutrients in the other. Children in elementary school are the best target forimprovement of community nutrition because in the childhood the function of the brain organbegan to form so the development of intelligence is quite rapid. Lack of nutritional intake inchildren can inhibit the physical growth and thinking ability in children and subsequently reduce inlearning interest. Therefore the nutritional status of the children must detect immediately to carryout the preventive measurements. Objective, the purpose of this study is to know the nutritionalstatus of children at grade VI in elementary school Miftakhul Ulum Surabaya based on height andweight. Methods, this study is a quantitative descriptive using survey method, weighting indexinstrument by height in children aged 6?17 years old from Health Department in 2011. This studyused the measurement of body weight and height. Subjects of this study were all students at grade VIin elementary school Miftakhul Ulum Surabaya, which amount 81 children. Data collecting techniques use anthropometric measurements which include measurement of body weight and heightthen calculated base of data analysis techniques using quantitative descriptive with percentage.Result, study results showed most of the students were 12 years old (56.80%), mostly male (55.60%).most of them have body height 130?140 cm (37.00%), and body weight 31?40 kg (46,90%). Malechildren have more problems with their nutritional status (51.10%). Male children much oftenhave underweight and over weight (13.30%) than girls. By the increasing their age, their BMI willbe normal category (100%). By the age of 13 and 14 years old, the children will not have underweight (0%). Conclusion, based on the nutritional status of all children at grade VI, it can beconcluded that the nutritional status of children at grade VI in elementary school Miftakhul UlumSurabaya is in underweight category (very thin and lean) with percentage 56.80%. While the normal weight percentage 32.10%, and over weight (fat and obesity) with percentage 11.10%.
PENGARUH PEMBERIAN TOPIKAL EKSTRAK KOLAGEN KULIT IKAN LELE SANGKURIANG (CLARIAS GARIEPINUS VAR) TERHADAP TNF-Α DAN JUMLAH FIBROBLAST PADA LUKA BAKAR DERAJAT DUA TIKUS WISTAR ., Aisyah; Mufarikoh, Zainatul; Andini, Ary
Jurnal Ilmu Kesehatan dan Kesehatan Vol 1 No 1 (2017): FEBRUARY
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v1i1.611

Abstract

ABSTRACTBackground: Collagen has vital role on healing process of burn injuries, mainly in connective tissue.Collagen triggers fibroblast proliferation, support to form new granulation tissue and epithelium aroundwound. Wound treatment through collagen extract of Sangkuriang catfish skin can increase healing process.It stimulates humidity on level II burn injuries and encourage re-epithelization, proliferation and cellmigration also increases growth. Methods: This is an experimental studies using 4 groups of RattusNorvegicus (Wistar strain). All of the group get a burn injuries in their back skin. Control group 1 (K1) wastreated by lidocaine for three days and control group 2 (K2) for ten days. Whereas treatment group 1 (P1) getlidocaine and collagen extract from Sangkuriang cat fish for 3 days and treatment group 2 (P2) for 10 days.Result: Number of fibroblast/field of view on treatment group showed significantly increased comparedcontrol groups on the 3rd days (P=0,046) and the 10th (P=0,004). Percentage of TNF-? on level II-burninjuries in wistar rats showed significant difference. Percentage of TNF-? lower than treatment group andshowed significant lowering level compared control groups on the10th (P=0,022). Conclusion: Increasing offiroblast number and lowering level of TNF-? significantly showed collagen extract of Sangkuriang cat fishskin accelerate wound healing process.
PENGARUH PEMBERIAN JUS BUAH BELIMBING WULUH (AVERRHOA BILIMBI L.) TERHADAP KADAR TRIGLISERIDA DARAH TIKUS PUTIH (RATTUS NORVEGICUS) JANTAN GALUR WISTAR YANG DIBERI DIET TINGGI LEMAK Fatichasari, Hilda Dwi
Jurnal Ilmu Kesehatan dan Kesehatan Vol 3 No 2 (2019): AUGUST
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v3i2.865

Abstract

ABSTRAK Latar Belakang: Hipertrigliseridemia merupakan suatu keadaan yang terjadi karena  peningkatan kadar trigliserida ?150 mg/dl. Pencegahan hipertrigliseridemia sangat diperlukan secara non farmakologi dengan mengubah gaya hidup sehari ? hari, apabila hal ini tidak berhasil dibutuhkan farmakoterapi menggunakan obat konvensional dan atau obat tradisional. Salah satu obat tradisional yang secara empiris digunakan untuk menurunkan trigliserida adalah buah belimbing wuluh (Averrhoa bilimbi L.). Tujuan: Tujuan penelitian untuk menilai efek pemberian jus buah belimbing wuluh terhadap kadar trigliserida tikus Wistar jantan. Metode: Desain penelitian eksperimental laboratorik. Hewan coba 24 ekor tikus Wistar jantan, dibagi secara acak kedalam 3 kelompok (n=8). Kelompok kontrol negatif hanya diberikan pakan biasa. Kelompok kontrol positif diberikan pakan tinggi lemak selama 28 hari. Kelompok perlakuan diberikan pakan tinggi lemak 28 hari dan jus buah belimbing wuluh dengan dosis 4ml/200grBB pada hari ke 15 selama 14 hari. Analisis data persentase penurunan kadar trigliserida menggunakan One-Way ANOVA, yang dilanjutkan uji Post Hoc dengan teknik LSD. Hasil: Pada kelompok kontrol negatif menunjukkan rerata kadar trigliserida sebesar 66,13 mg/dl. Sedangkan pada kelompok kontrol positif, hasil penelitian menunjukkan adanya peningkatan rerata kadar trigliserida sebesar 96,13 mg/dl. Pada data penelitian didapatkan nilai p = 0,048 (p < 0,05), sehingga dapat disimpulkan bahwa terdapat kenaikan kadar trigliserida yang bermakna. Kenaikan ini menunjukkan bahwa diet tinggi lemak dapat meningkatkan kadar trigliserida darah. Kesimpulan: Jus Buah Belimbing Wuluh dapat menurunkan kadar trigliserida namun tidak signifikan secara statistik. Kata Kunci: Trigliserida, diet tinggi lemak, Belimbing wuluh (Averrhoa bilimbi L.)

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