cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Hotimah
Contact Email
mhsj@unusa.ac.id
Phone
-
Journal Mail Official
mhsj@unusa.ac.id
Editorial Address
-
Location
Kota surabaya,
Jawa timur
INDONESIA
Medical and Health Science Journal
Published by Universitas Nahdlatul Ulama Surabaya
ISSN : 25497588     EISSN : 25497596     DOI : https://doi.org/10.33086/mhsj
Core Subject : Health, Social,
Health Professions Social Sciences
Medical and Health Science (MHSJ) published peer-reviewed original articles research, case report or article review. This journal is published twice (February and August) by Faculty of Medicine Universitas Nahdlatul Ulama Surabaya.
Arjuna Subject : -
Articles 155 Documents
 3   4   5   6   7 
PENGARUH PEMBERIAN JUS BUAH APEL MANALAGI (MALUS SYLVESTRIS) TERHADAP KADAR TRIGLISERIDA DARAH TIKUS PUTIH (RATTUS NORVEGICUS) JANTAN GALUR WISTAR YANG DIBERI DIET TINGGI LEMAK Rahmat, Reni Rabiatul; Suyono, Bambang; Risma, Risma
Jurnal Ilmu Kesehatan dan Kesehatan Vol 3 No 2 (2019): AUGUST
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v3i2.866

Abstract

Manalagi apples (Malus sylvestris) have long been believed to have the effect of lowering blood cholesterol levels. Where the main content is quercetin class of flavonoids as antioxidants and pectin which functions as fat absorption. This study was an experimental study with a randomized post test only control group design study conducted for 28 days and using 30 rats divided into 3 groups. In all groups given a high fat diet with treatment, control (-) was given a high fat diet, control (+) was given simvastatin and KP1 was given Manalagi apple juice (Malus sylvestris) dose of 10 ml/day. One-Way ANOVA test results from measurements of triglyceride levels showed p = 0.139 (p> 0.05) so that Manalagi apple juice (Malus sylvestris) did not significantly affect blood triglyceride levels of male Wistar strains (Rattus norvegicus) given high fat diet. Keywords: Apple Fruit Juice, Triglycerides, High fat Buah apel Manalagi (Malus sylvestris) telah lama dipercaya memiliki khasiat menurunkan kadar kolesterol darah. Dimana Kandungan utamanya adalah quercetin golongan flavonoid sebagai antioksidan dan pektin yang berfungsi sebagai penyerapan lemak. Penelitian ini bertujuan untuk mengetahui apakah ada pengaruh jus kulit dan daging buah apel Manalagi(Malus sylvestris) terhadap kadar trigliserida darah tikus putih jantan galur wistar (Rattus norvegicus) yang diberi diet tinggi lemak sebelumnya. Penelitian ini merupakan penelitian eksperimental dengan  rancangan penelitian randomized post test only control group design yang dilakukan selama 28 hari dan menggunakan 30 ekor tikus yang dibagi menjadi 3 kelompok. Pada semua kelompok  diberi diet tinggi lemak dengan perlakuannya, kontrol (-) diberi diet tinggi lemak, kontrol (+) diberi simvastatin dan KP1 diberi jus buah apel Manalagi (Malus sylvestris) dosis 10 ml/hari. Hasil uji One-Way ANOVA dari pengukuran kadar trigliserida menunjukan p = 0,139 (p > 0,05) sehingga pemberian jus buah apel Manalagi (Malus sylvestris) tidak berpengaruh secara signifikan terhadap kadar trigliserida darah tikus putih (Rattus norvegicus) jantan galur wistar yang diberi diet tinggi lemak. Kata kunci: Jus Buah Apel, Trigliserida, Diet tinggi lemak.
PENGGUNAAN PENANDA BIOLOGIS ANGIOGENIK RASIO s-Flt1 DAN PIGF SEBAGAI PREDIKTOR PREEKLAMSIA Levani, Yelvi
Jurnal Ilmu Kesehatan dan Kesehatan Vol 3 No 1 (2019): FEBRUARY
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v3i1.920

Abstract

Preeclampsia is a leading cause of maternal death worldwide. Preeclampsia involves multi-organ and characterized by hypertension and proteinuria. One of the hypothesis pathogenesisin preeclampsia is placental insufficiency. Its causing imbalance between angiogenic and antiangiogenic factors in maternal circulation. This imbalance factors are responsible for systemic vasoconstriction. However, until now, there is no predictor for preeclampsiain high risk pregnancy. Therefore, this review briefly describes the recent studies about utility of biologic angiogenesis marker, such as s-Flt1 and PIGF as predictor in preeclampsia
PENGARUH EKSTRAK DAUN PEPAYA (Carica papaya) TERHADAP KEMATIAN LARVA NYAMUK Aedes agypti INSTAR III Payangka, Jonathan; Risma, Risma; Wibowo, Prajogo
Jurnal Ilmu Kesehatan dan Kesehatan Vol 3 No 1 (2019): FEBRUARY
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v3i1.921

Abstract

Background: Papaya leaves (Carica papaya) extract is a natural larvacide that contains papain and alkaloid karpain so its usage is safe for the environment. The larvacide properties can also be used to reduce the amount of Aedes aegypti mosquito larvae. This mosquito species is the main vector for the virus that causes dengue fever which incident number increases over the years. There have been a few methods used to control the mosquito?s amount, one of which is by decreasing the number of Aedes aegypti?s larvae using the organophosphate insecticide chemical known as temefos. Temefos is really effective in killing the Aedes aegypti larvae but it has a lot of side effects especially towards the environment. By controlling the number of the Aedes aegypti?s larvae, hopefully the number of the dengue fever case can also be reduced. Objective: To prove that the papaya leaves (Carica papaya) extract have effects on the death of Aedes aegypti?s instar III larvae. Method: This is an experimental research what uses a post test only control group design. The study consists of seven groups, which are positive control that is given abate powder, negative control that is given only aquadest, and five groups treated with concentrations of 0.5%, 1%, 1.5%, 2%, and 2.5%; repeated for four times. The calculation of the amount of dead larvae is done within the first 24 hours. Result: Based on the Kruskal-Wallis test, p?s value is <? with p value being 0.000 and ? being 0.05. It proves the significance of the experiment. Conclusion: The papaya leaves (Carica papaya) extract have effects on the death of Aedes aegypti?s instar III larvae
HUBUNGAN ANTARA AKTIVITAS BELAJAR KELOMPOK DENGAN INDEKS PRESTASI MAHASISWA SEMESTER 6 FAKULTAS KEDOKTERAN UNIVERSITAS HANG TUAH SURABAYA TAHUN AJARAN 2017/2018 Handajani, Fitri; Hapsari, Kinanti; Garianto, Efyluk
Jurnal Ilmu Kesehatan dan Kesehatan Vol 3 No 2 (2019): AUGUST
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v3i2.1070

Abstract

One of the active learning methods is to do a study group. Researcher is interested in research on the correlation between study group activities and student?s grade, so that students can find learning methods which may influence academic outcomes and facilitate learning, especially the medical students. This observational analytic study was carried out with a cross sectional design. The data of this study were obtained from the answers to the respondent's questionnaire in the Medical Faculty of Hang Tuah University, Surabaya. The sample in this study were semester 6 students of the 2017/2018 academic year at the Faculty of Medicine, University of Hang Tuah Surabaya (130 respondents). Based on the Spearman correlation statistical test between study group activities with the 6th semester students grade point, the significance of the correlation between study group activities and the 6th semester students grade point is 0.687. With a value of ? = 0.05, means p> ?, it can be concluded that the correlation between the two variables is not significant so that H0 accepts and H1 is rejected. So, there is no correlation between study group activities with 6th semester grade point. There is no correlation between study group activities and the 6th semester students grade point in the Faculty of Medicine, Hang Tuah University Surabaya.
KOMORBIDITAS GANGGUAN PEMUSATAN PERHATIAN DAN HIPERAKTIVITAS PADA ANAK Tantiwi, Olga Fanny
Jurnal Ilmu Kesehatan dan Kesehatan Vol 3 No 2 (2019): AUGUST
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v3i2.1132

Abstract

GPPH merupakan bagian terbesar dari anak yang dibawa orangtua untuk berobat ke psikiater anak. Anak GPPH yang dirujuk ke klinik banyak yang menunjukkan gangguan lain yang menyertai diagnosis utama yang disebut sebagai komorbiditas. Sangat penting untuk mendeteksi kehadiran komorbiditas ketika anak didiagnosis GPPH karena dapat menjadi tantangan diagnostik, manifestasi akan lebih kompleks serta prognosis akan lebih buruk dibandingkan dengan anak-anak dengan GPPH saja. Tujuan penelitian untuk mengetahui jenis gangguan komorbid pasien anak GPPH, perbedaan faktor risiko pasien anak GPPH dengan komorbiditas maupun tanpa komorbiditas. Penelitian ini menggunakan desain deskriptif kuantitatif, dengan teknik total sampling. Terjangkau 84 kasus paisen anak GPPH di RSJD Atma Husada Mahakam Samarinda periode 2015-2018 dan didapatkan sebanyak 18 (21%) pasien anak GPPH tanpa komorbid, 52 (62%) memiliki 1 komorbid dan sebanyak 14 (17%) pasien yang memiliki >1 komorbid. Gangguan Spektrum Autisme(GSA) merupakan jenis gangguan komorbid terbanyak yaitu terdapat 28 (35%) kasus. Faktor risiko yang paling menonjol dari pasien anak GPPH dengan komorbiditas adalah faktor natal dengan persentase 39% dan faktor pengasuhan parsial yaitu sebanyak 18%, sedangkan faktor risiko yang paling menonjol dari pasien anak GPPH tanpa komorbiditas adalah faktor postnatal dengan persentase 33% dan tidak adanya kasus yang ditemukan sebagai faktor pengasuhan parsial.
UNCONTROLLED TYPE 1 DIABETES MELLITUS WITH TUBERCULOMA IN INFERIOR LOBE LEFT LUNG AND BILATERAL HYDRONEPHROSIS IN CHILD Wardhana, Anggia Rarasati; Sukartini, Sukartini; Muhyi, Annisa
Jurnal Ilmu Kesehatan dan Kesehatan Vol 3 No 2 (2019): AUGUST
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v3i2.1155

Abstract

Diabetes Mellitus (DM) is an important risk factor for the development of active tuberculosis (TB). It is chronic and will weaken the immune system causing the patient have increased risk of tuberculosis by three-fold.We present a case of 13-year-old girl with chest pain and cough. She has a previous history of type 1 DM. Laboratory findings showed hyperglycemic state. Thoracic CT showed tuberculoma of inferoposterior lobe left lung, while abdominal CT showed bilateral hydronephrosis. He was then administered TB treatment of 2HRZE/10RH, corticosteroid, and insulin regiments with strict monitoring of blood glucoses. Clinical symptoms and blood glucose level were significantly improved after treatment.
REVIEW ARTICLE: DEVELOPEMENT AND USING DENGUE VACCINE FOR DENGUE INFECTION VIRUS Massey, Firdaus Kabiru; Yulia, Rika
Jurnal Ilmu Kesehatan dan Kesehatan Vol 3 No 2 (2019): AUGUST
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v3i2.1194

Abstract

Abstract : Tropical and subtropical countries are regions with high incidence of dengue infection. Dengue virus infection is estimated to cause 300 million new infections in one year and approximately 1 million severe cases with 2 + 5% deaths. The case of dengue in Indonesia has continued to increase since 1968 until 1980 where all provinces in Indonesia have been affected by the dengue virus. Dengue virus is a virus carried by the Aedes aegypti mosquito in its salivary gland. The virus which is a family group of Flaviviruses has four homologous serotypes, namely DENV-1, DENV-2, DENV-3, and DENV-4, which can cause dengue infection in individuals. Currently there is a shift in the target population from children to adults. This is a problem that needs to be resolved by the government and the community itself. Solution to overcome this, the government needs early prevention efforts to reduce the severity of dengue infection by developing and researching dengue vaccines. Currently a vaccine has been found that can be used as prophylaxis for dengue virus, namely Dengvaxia. This vaccine has been recommended by the World Health Organization (WHO) as prophylaxis for dengue infection, but Dengvaxia is only used in areas that are very endemic to dengue fever. The Indonesian Food and Drug Supervisory Agency (BPOM RI) has also approved the use of Dengvaxia as an indication of prevention of dengue infection since August 31, 2016. This vaccine has been approved globally only given to individuals aged between 9-16 years.  Keyword : dengue virus, dengvaxia vaccine, Aedes aegypti, endemic
REVIEW ARTICLE: AMEBIASIS MOLECULAR PATHOGENESIS DEVELOPMENT Muliani, Nurlina; Salim, Hotimah Masdan
Jurnal Ilmu Kesehatan dan Kesehatan Vol 3 No 2 (2019): AUGUST
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v3i2.1195

Abstract

Amebiasis is one of the gastrointestinal tract infection disease caused by Entamoeba histolytica ,a parasitic protozoan. Amebiasis is the second disease, caused by parasite, that leading cause of death after malaria. Infection occurs through faecal-oral route and after ingestion a contaminated food and beverages by human faeces. The pathogenesis of E. histolytica can be classified into 3 processes, i.e: death of host cell, inflammation, and parasitic invasion. The recent years, a molecularly amebiasis pathogenesis has been developed, i.e: adherence, phagocytosis, tropogocytosis of host cell and how the parasites can survive and attack host cells so it can cause an infection in humans. Molecular development is an important thing to be considered in the selection of amebiasis therapy.
CHITOSAN AS ANTIFUNGAL IN CHANNA STRIATA COLLAGENCHITOSAN FOR WOUND HEALING Andini, Ary; Prayekti, Endah
Jurnal Ilmu Kesehatan dan Kesehatan Vol 3 No 2 (2019): AUGUST
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v3i2.1197

Abstract

The Snakehead fish contains high protein that was mostly used as a treatment during healing process in either invasive or passive surgery. Therefore, it could be developed as well as a mixture of wounds dressing for skin healing. The aim of this study was to know the effect of  combination of concentrations between chitosan and collagen of  Snakehead fish  (Channa striata) skin and scales on fungal total number recovered from the composite. Snakehead fish skin and scales was treated by soaking in 2% HCl solvent for 48 hours to obtain collagen from its filtrate. Filtrate obtained continued to neutralize with 1 M NaOH until soluble collagen  appeared. Collagen obtained in this study then  mixed with 2% chitosan liquid to make wound dressing in various concentrations group. Combination of colagen mixture in this study were chitosan liquid only as control, 25% collagen-75% chitosan (C1), 50% collagen-50% chitosan (C2) and 75% collagen-25% chitosan (C3). The study results showed that on Control, C1 and C2 group there was no fungal contamination, but on C3 group there was contamination of fungal with total counting about 2,43 x 103 CFU. Based on statistically test showed that there was discrepancy for each group with p-value was 0,02 (p<0,05).
THE DIFFERENT EFFECTS OF ZINC SUPPLEMENT AND VELVET BEAN MUCUNA PRURIENS EXTRACTS TOWARD FERTILITY OF BALBC/ MICE
Jurnal Ilmu Kesehatan dan Kesehatan Vol 2 No 2 (2018): AUGUST
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v2i2.582

Abstract

Abstract: Good quality velvet beans and zinc supplement are well studied and known as rich source ofaphrodisiac. The following reseach was carried out to study the difference effect of zinc supplement (ZS)and velvet bean extracts (VBE) towards fertility of BALB/c mice i.e the number of sperm, the motility ofsperm, the viability of sperm, the morphology of sperm, the existence of vagina plug, and the birthcondition of mice. This study was an experiment using Posttest Only Controlled Group Design with threegroups. The first group (A1) as control, the second group (A2) receives subcutaneous injection of 2-methoxyethanol fraction as much as 200 mg/kg weight/day for 5 days, followed with ZS at a dosage of0,026 mg/day/head, and the third group (A3) receives subcutaneous injection of 2-methoxyethanolfraction as much as 200 mg/kg weight/day for 5 days, followed with VBE at a dosage of 56 mg/kg weight/day for 30 days. The quality of spermatozoa of A1, A2, and A3 was significant difference (p < 0.05).Both of A2 and A3 were no significant difference of mean number of sperm (p = 0.274), mean percentageof sperm motility (p = 0.739), mean percentage of sperm viability (p = 0.141) and mean value ofmorphology of sperm (p = 0.394). The quality of spermatozoa and the total number of baby mice livedand died of A1, A2 and A3 were significant difference. In addition, there was no significant differencein the existence of female mice's vaginal plug of A1, A2 and A3. This study showed that ZS and VBE canincrease the quality of spermatozoa of BALB/C mice.

Page 5 of 16 | Total Record : 155

 3   4   5   6   7 

Filter by Year

2017 2023


Reset
Filter By Issues
All Issue Vol 7 No 01 (2023): FEBRUARY Vol 6 No 02 (2022): AUGUST Vol 6 No 1 (2022): FEBRUARY Vol 5 No 2 (2021): AUGUST Vol 5 No 1 (2021): FEBRUARY Vol 4 No 2 (2020): AUGUST Vol 4 No 1 (2020): FEBRUARY Vol 3 No 2 (2019): AUGUST Vol 3 No 1 (2019): FEBRUARY Vol 3 No 1 (2019): February Vol 2 No 2 (2018): AUGUST Vol 2 No 2 (2018): AUGUST Vol 2 No 1 (2018): FEBRUARY Vol 2 No 1 (2018): FEBRUARY Vol 1 No 2 (2017): AUGUST Vol 1 No 2 (2017): AUGUST Vol 1 No 1 (2017): FEBRUARY Vol 1 No 1 (2017): FEBRUARY More Issue