cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Nursalam Hamzah
Contact Email
djps@uin-alauddin.ac.id
Phone
+6282117170860
Journal Mail Official
djps@uin-alauddin.ac.id
Editorial Address
universitas Islam Negeri Alauddin Makassar, Indonesia
Location
Kab. gowa,
Sulawesi selatan
INDONESIA
ad-Dawaa : Journal of Pharmaceutical Sciences
Published by Universitas Islam Negeri Alauddin Makassar
ISSN : 26547392     EISSN : 26546973     DOI : 10.24252/djps
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology
ad-Dawaa Journal of Pharmaceutical Sciences (DJPS) merupakan jurnal yang terbit dua kali dalam setahun, yaitu setiap Juni dan Desember. Jurnal ini fokus pada seluruh bidang terkait ilmu farmasi, termasuk biologi farmasi, farmakokimia, farmakologi, farmasi klinik dan teknologi farmasi. Jurnal ini juga mempublikasikan artikel terkait integrasi Islam dengan ilmu farmasi.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 83 Documents
 3   4   5   6   7 
Antianemic Activity of Coconut (Cocos nucifera) Haustorium Waste Filtrate in Mice Induced by Sodium Nitrite Adzimahtinur Pradawahyuningtyas; Mukti Priastomo; Laode Rijai
Ad-Dawaa: Journal of Pharmaceutical Sciences Vol 3 No 2 (2020)
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/djps.v3i2.16477

Abstract

This study aims to determine the antianemic activity of coconut haustorium (Cocos nucifera) waste against mice induced by sodium nitrite orally for 43 days. The condition of anemia was determined by calculating the hemoglobin level using the Point of Care Test (POCT) method with the easytouch® GCHb and the resulting Hb level was 7.96 ± 0.05 g/dL. After the anemia condition is achieved, the test treatment is given for 21 days by dividing the mice into four groups, each consisting of three mice. The blank group (I) was administered distilled water, the control group (II) was administered Inbion® supplements at a dose of 0.65 mg/20 g BW, groups III and IV were administered coconut haustorium filtrate at a dose of 5 and 15 g/kg, respectively. Then measured the hemoglobin level and the number of erythrocytes. Based on the results of the study, the average hemoglobin levels of the blank, control, I and II groups were 13,9; 15,4; 16,0; and 16.8 g / dL, respectively. The number of erythrocytes during anemia was 1,750,000 / mm3 and after giving coconut kentos was 8,260,000 / mm3. From this study it can be concluded that the highest anti-anemia activity showed by coconut haustorium waste filtrate at dose 15 g/kgBW and had a significant difference in hemoglobin levels (p <0.05) with the blank group.
Potential of Sweet Orange Peels (Citrus sinensis) Essential Oil as Sunscreen Isriany Ismail; Fatma Dewi; Ferawati Ferawati; Nursalam Hamzah
Ad-Dawaa: Journal of Pharmaceutical Sciences Vol 3 No 2 (2020)
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/djps.v3i2.20720

Abstract

Telah dilakukan penelitian tentang uji efektifitas minyak atsiri kulit buah jeruk manis (Citrus sinensis) sebagai tabir surya secara spektrofotometer UV-VIS. Penelitian ini bertujuan untuk menentukan potensi dari minyak atsiri kulit jeruk manis sebagai tabir surya yang ditentukan dengan nilai SPF, transmisi eritema dan transmisi pigmentasi. Minyak atsiri jeruk diperoleh dengan mengekstraksi kulit buah jeruk manis dengan metode pengepresan/pemerasan. Pengujian dilakukan menggunakan metode spektrofotometri UV pada panjang gelombang 290 – 400 nm terhadap konsentrasi minyak atsiri 20, 40, 60, 80, 100, dan 120 bpj. Hasil analisis menunjukkan bahwa minyak atsiri kulit buah jeruk manis (Citrus sinensis) mengabsorbsi sinar UV B hingga UV A dengan nilai SPF 1,094 hingga 1,380. Persen eritema dan pigmentasi pada konsentrasi 120 bpj berturut-turut adalah 66,98% dan 65,54%.
Kemuning Leaves Extract Gel (Murraya panicula L.): A Study of Quality and Efficacy in Healing Burns Khairunnisa Hasbullah; Faridha Yenny Nonci; Muh. Ikhlas Arsul
Ad-Dawaa: Journal of Pharmaceutical Sciences Vol 3 No 1 (2020)
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/djps.v3i1.13984

Abstract

This study aims to determine the activity of kemuning leaves extract in healing burns, and efficacy and quality of the extract in gel dosage form. The research was started with kemuning leaves extraction used maceration method with ethanol 96%, ethyl acetate and n-hexane as solvent. Each extract was activity tested for healing burn in rabbits. The extract that is most effective in wound healing then formulated into gel. The gel preparations were made in 3 variations of concentration, namely 5% (FI), 10% (FII), and 15% (FIII), with basis by carbopol 940 gel, triethanolamine, and methyl paraben. Then, gels were tested for efficacy and quality. The efficacy test follows the activity test procedure. Gel quality test includes organoleptic, pH, viscosity, dispersibility, and homogenity. The activity test showed that ethanol 96% extract, ethyl acetate and n-hexane healed burns in 13,3; 14,3; and 15,3 days, respectively. While the results of the gel efficacy test for FI, FII and FIII were 13,6; 11,6; and 9,6 days, respectively. In general, all gels have good qualities in every parameter, except the viscosity of FII and FIII which is slightly higher. Based on the results of the research, ethanol 96% extract was the most effective in healing burn. In addition, FIII gel has the best efficacy with good qualities except viscosity.
Formation of Hydrochlorothiazide – Para-aminobenzoic Acid Cocrystals by Solvent Evaporation Method Haeria Doloking; Ayu Tri Sartika; Nurshalati Tahar
Ad-Dawaa: Journal of Pharmaceutical Sciences Vol 4 No 1 (2021)
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/djps.v4i1.21301

Abstract

Hydrochlorothiazide is a diuretic drug used for mild to moderate hypertension were classified in Class II BSC. The purpose of this study was to explore the formation of hydrochlorothiazide-para-aminobenzoic acid cocrystal by solvent evaporation method. Cocrystals are prepared with a molar ratio of 1:0; 1:1; 1:2; and 2:1 between hydrochlorothiazide and para-aminobenzoic acid. The cocrystals were characterized by Scanning Electron Microscopy (SEM), X-ray Diffractometry (XRD), Differential Scanning Calorimetry (DSC), and Fourier Transform Infrared (FT-IR) spectrophotometer. The hydrochlorothiazide-para-aminobenzoic acid cocrystal has new crystalline peaks at 2θ of 14.904o; 15.41o; 25.553o; 26.5o; 29.844o; 31.083o indicating the formation of a new crystalline phase. The cocrystal showed the melting point at 188.57oC which is different from the initial components. The FTIR spectra of cocrystal showed the shifting of absorption peaks of groups of initial components indicating of formation of hydrochlorothiazide-para-aminobenzoic acid cocrystal through intermolecular hydrogen bond interactions between amine/sulfonamide group and carboxyl group.
Antituberculosis Activity of Parang Romang (Boehmeria virgata (Forst.) Guill) Stem Extract Muhammad Rusdi; Muhammad Ikhlas; Nur Pratiwi Kartikasari
Ad-Dawaa: Journal of Pharmaceutical Sciences Vol 4 No 1 (2021)
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/djps.v4i1.21359

Abstract

Parang Romang (Boehmeria virgata (Forst.) Guill) is one of the plants empirically used by the people of South Sulawesi. This study aimed to test the activity of Parang Romang Extract against Mycobacterium tuberculosis. The 96% ethanol extract obtained was fractionated by the liquid-solid extraction method: obtained n-Hexan soluble extract and n-Hexan insoluble extract. Samples of 96% ethanol extract, soluble extract of n-Hexan and insoluble extract of n-Hexan were made in series of concentrations of about 25, 50, 75, and 100 µg/ml. The inhibition test of Mycobacterium tuberculosis used the MODS method on the Mycobacterium tuberculosis strain H37RV. Color reagents then identify extracts that provide inhibition. The results of the minimum inhibition concentration of Mycobacterium tuberculosis showed that a 100 µg/ml of n-Hexan soluble extract was able to inhibit the growth of Mycobacterium tuberculosis strain H37RV.
Characterization and Screening Active Phytochemical Compounds of 70% Ethanol Extract of Mahogany Seed (Swietenia mahagoni Jacq.) I Putu Gede Adi Purwa Hita; Putu Eka Arimbawa; Ni Putu Aryati Suryaningsih
Ad-Dawaa: Journal of Pharmaceutical Sciences Vol 4 No 1 (2021)
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/djps.v4i1.21225

Abstract

One of the herbal medicinal plants in Indonesia with antidiabetic activity is mahogany (Swietenia mahagoni Jacq.). Differences in plant parts used, extraction methods, and solvents during the extraction process will result in different characterization, quantity, and active phytochemical compounds in the extract. This study aimed to determine the content of active phytochemical compounds and extract characteristics of mahogany seed that fit the standards. Extracts were made using the maceration method with 70% ethanol solvent, then extract was characterized, and phytochemicals of active compounds were screened using reagents according to each group of compounds' test method. 50.16 g of 70% ethanol extract of mahogany seeds produced in this study had a solid form, characteristic odor, bitter taste, and brown color. The extract has the characteristics of water content, total ash content, acid insoluble ash content, water-soluble extracts content, and soluble ethanol extracts content according to the standard. Several classes of active compounds were identified qualitatively in the extract, which are flavonoids, phenolics, terpenoids, steroids, glycosides, and saponins. It appears that 70% ethanol extract of mahogany seed has a characterize extract that meets the standards and contains several active phytochemical compounds as potential antidiabetic agents.
Pediculicidal Activity of Cem-ceman White Cempaka Flower (Michelia alba DC.) against Pediculus humanus capitis Ahmad Fadli Robby; Iman Surya Pratama; Galuh Tresnani
Ad-Dawaa: Journal of Pharmaceutical Sciences Vol 4 No 1 (2021)
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/djps.v4i1.21154

Abstract

The prevalence of pediculosis reported in Asia has ranged from 0.7% to 59%. High resistance and side effects is a challenge in using the pediculicidal agents. The widely use and empirical as well as scientific studies of traditional plants for anti-lice were already done, one of them is cempaka. The aim of this study was to determine the pediculicidal activity of cem-ceman white cempaka flower (Michelia alba DC.) on Pediculus humanus capitis in vitro. The white cempaka flowers made into cem-ceman preparations by mixing and soaking in coconut oil until 3 days. Pediculisidal activity was tested by filter paper diffusion test method with 3 replications. Data were analyzed using Kruskal-Wallis followed by post hoc Mann-Whitney Method test with software SPSS v.16. The phytochemical screening showed that sample contains alkaloid, tannin, saponin, and triterpenoid. Pediculidal activity test showed that cem-ceman white cempaka flower has pediculicidal effect in 10% concentration (w/v) with 66.67% mortality and 15% concentration (w/v) with 77.33% mortality. In conclusion cem-ceman white cempaka flowers has pediculicidal activity at concentration 10% and 15% but lower than permethrin 1%  (p<0.05).
Effect of Kombucha Tea on Total Cholesterol Decreasing Levels in White Rats (Rattus norvegicus) Zulkifli Halid; Sulaiman Sulaiman; Rifka Irhamna
Ad-Dawaa: Journal of Pharmaceutical Sciences Vol 4 No 1 (2021)
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/djps.v4i1.21205

Abstract

The purpose of this study was to determine the type of content of 75% kombucha tea that is fermented for 12 days,  there are black tea, green tea, and the packaged tea. Fifteen Rattus norvegicus was randomized divided into 5 groups and each group consisted of 3 rats. Group I or the negative control was given aquadest, group II was given kombucha packaged tea, group III was given black tea kombucha, and group IV was given green tea kombucha. Group V as a positive control was given simvastatin. All groups were injected with the samples solution orally. Evaluation of effects was carried out by observed the cholesterol total level before and after treatment. The results showed that all kombucha tea can reduced the total cholesterol level on rats (Rattus norvegicus). Conclusion: Data were analyzed using ANOVA followed by Duncan test with 95% confidence level using SPSS 20.0 software, results showed that black tea kombucha 1.8 mL of 75% concentration has an optimal reduced total cholesterol levels in rats (Rattus norvegicus).
Antibacterial Activity Of Musa Paradisiaca Var. Sapientum Peel Extrak Cream And Ointments Dosage Form On Staphylococcus Aureus solikah ana estikomah
Ad-Dawaa: Journal of Pharmaceutical Sciences Vol 4 No 1 (2021)
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/djps.v4i1.21303

Abstract

The aim of the present study was to determine the difference of antibacterial effectivity between ointment  and cream Musa paradisiaca var. Sapientum (MPvS) peel extract against bacteria Staphylococcus aureus. Objective: To prove the antibacterial effect of banana peel extract with 5%,10%,15% concentration cream and oitments on Staphylococcus aureus. Methods: This study was applying the true experimental design with analyzed statistically with the ANOVA test and continued with the Duncan test to determine the level of treatment that provided the difference and the T-test to determine the most effective differences between groups. The results of the antibacterial activity of cream with a concentration of 10% with an inhibition zone diameter of 12.80 mm and Ointment at a concentration of 15% with an inhibition zone value of 11.07 mm were able to inhibit antibacterial activity. Conclusion, banana peel MPvS extract Cream Formula is the most effective in inhibiting the growth of Staphylococcus aureus bacteria.
Herbs Used as Antidiabetic : A Review Jufri Ubrusun; Suharjono Suharjono; Irma Novrianti
Ad-Dawaa: Journal of Pharmaceutical Sciences Vol 4 No 2 (2021)
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/djps.v4i2.23461

Abstract

Diabetes mellitus is a syndrome characterized by a condition of hyperglycemia, and changes in the metabolism of lipids, carbohydrates, and proteins. Diabetes mellitus is characterized by an increase in glucose levels caused by insulin deficiency either in absolute or relative terms. Diabetes mellitus therapy is a long-term therapy and is relatively expensive.   Therefore, it is necessary to look for effective alternative drugs with low prices such as herbal medicines derived from plants. Indonesia is one of the countries that has a diversity of plants, so many plants that grow in Indonesia can be used as an alternative therapy to overcome diabetes mellitus. This paper aims to provide a relevant review of medicinal plants used for diabetes mellitus that has been carried out in research on tested animals. This research was conducted by searching for national and international articles from the internet, which were searched from 2011 to 2019, including original articles, and experimental articles, about Traditional medicine for diabetics. The following keywords are used : [[ “studi in vivo tumbuhan obat untuk diabetes” OR “Uji efektifitas ekstrak tumbuhan sebagai antidiabetik” OR “tumbuhan sebagai antidiabetik” ]] OR [["Test extract activity against diabetic mice" OR "antidiabetic plant" OR "antidiabetic herbal medicine" OR "antidiabetic in rat”, “Traditional medicine of diabetisin Indonesia” ]]. From the results of the literature study, it was found that 21 articles with 24 medicinal plants were tested in vivo on test animals to reduce blood sugar in diabetes mellitus. These medicinal plants contain compounds of the type of flavonoids, alkaloids, tannins, saponins, polyphenols, terpenoids, and phenolics that can have a therapeutic effect on decreasing blood sugar levels in test animals.

Page 5 of 9 | Total Record : 83

 3   4   5   6   7 

Filter by Year

2018 2023


Reset
Filter By Issues
All Issue Vol. 6 No. 1 (2023) Vol 5 No 2 (2022) Vol 5 No 1 (2022) Vol 4 No 2 (2021) Vol 4 No 1 (2021) Vol 3 No 2 (2020) Vol 3 No 1 (2020) Vol 2 No 2 (2019) Vol 2 No 1 (2019) Vol 1 No 2 (2018) Vol 1 No 1 (2018) More Issue