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INDONESIA
Jurnal Insan Farmasi Indonesia
Published by Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin
ISSN : 26213184     EISSN : 26214032     DOI : https://doi.org/10.36387/jifi
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology Physics
Focus and Scope Jurnal Insan Farmasi Indonesia (JIFI) is a broad-based primary journal covering all branches of pharmacy and its sub-disciplines that contains complete research articles, short communication and review articles. JIFI is a forum for the publication of quality and original works that open discussions in the field of pharmacy and health sciences.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 16 Documents
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Search results for , issue "Vol 2 No 1 (2019)" : 16 Documents clear
PENETAPAN KADAR FENILBUTAZON DAN PARASETAMOL DIDALAM JAMU PEGAL LINU YANG BEREDAR DI KOTA MALANG SECARA KROMATOGRAFI LAPIS TIPIS DENSITOMETRI Rollando Rollando; Erizcha Debora Embang; Eva Monica
Jurnal Insan Farmasi Indonesia Vol 2 No 1 (2019)
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

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Abstract

Traditional medicine or commonly known as herbal medicine is often found, because its free to use without consulting medical therefore. Chemical drugs in the herbal products are still often found. Drug chemicals often added to herbs are paracetamol and phenylbutazone. In this study TLC Densitometry system used to detect paracetamol and phenylbutazone, to get optimal TLC system, validation includes selectivity, linearity, accuracy, precision, LOD and LOQ, determination of paracetamol and phenylbutazone in herbal samples.Optimal mobile phase for detection paracetamol and phenylbutazone is ethyl acetate : chloroform (2:1). Maximum wavelength of 240 nm paracetamol, 237 nm phenylbutazone. The method used has selectivity, linearity and met the criteria of accuracy and precision, but the limit detection and limit quantitation do not met requirements. The result of the study 30 samples of herbs, found 5 samples were positive containing phenylbutazone that samples j, k, s, u and v with successive percentpercentages of 9,5053%; 10,6138%; 62,8776%; 42,8839% and 24,9238%.
STUDI PREFORMULASI KELARUTAN MINYAK ATSIRI MASOYI (Massoia aromatica Becc.) dalam SELF-MICROEMULSIFYING DRUG DELIVERY SYSTEM (SMEDDS) Devilke Yandriyani; Eva Monica; Rollando Rollando; Hendry Setiawan; Rehmadenta Sitepu
Jurnal Insan Farmasi Indonesia Vol 2 No 1 (2019)
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

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Abstract

Self-Emulsifying Drug Delivery System (SEDDS) merupakan salah satu metode yang digunakan untuk memperbaiki bioavailabilitas obat yang memiliki kelarutan dan absorpsi buruk dan biasanya digunakan untuk bahan aktif yang termasuk dalam BCS kelas II. Formulasi Self-Microemulsifying Drug Delivery System (SMEDDS) menggunakan beberapa komponen minyak, surfaktan, dan kosurfaktan. Parameter yang digunakan dalam formulasi meliputi studi kelarutan, penetapan kandungan lakton, skrining surfaktan dan kosurfaktan serta diagram fase pseudoterner. Komponen surfaktan, kosurfaktan dan minyak yang dipilih yaitu tween 80, PEG 400 dan minyak jarak. Formula Self-Microemulsifying Drug Delivery System (SMEDDS) terdiri dari 60% surfaktan dan kosurfaktan (4:1), 30% minyak jarak dan 10% minyak masoyi (Massoia aromatica Becc.).
DAMPAK KONSUMSI KOPI ARABIKA ESPRESSO DALAM MENURUNKAN KADAR GLUKOSA DARAH PADA PASIEN DIABETES MELITUS TIPE 2 Dhigna Luthfiyani Citra Pradana; Aprilla Ayu Wulandari
Jurnal Insan Farmasi Indonesia Vol 2 No 1 (2019)
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

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Abstract

Diabetes mellitus patients in 2013 had 382 millions people in the world dan approximately increase to 592 millions people who suffered diabetes mellitus in 2035. Consuming coffee can reduce risk factor of diabetes mellitus trough improving hyperglycemia in diabetes-induced mice. Coffee of Arabica Aceh Gayo is a original plant of Aceh Indonesia can consumed of people with processing coffee beans as a drink. Clinical Research of patients of diabetes mellitus type 2 who consume coffee Arabica espresso and patients of diabetes mellitus type 2 do not consume coffee Arabica espresso. The objective of research know to affected decreasing blood glucose from clinical data of fasting blood glucose. The clinical research of quasi experimental of after and before with control design. Total population of diabetes mellitus type 2 patients at UPN Veteran Jakarta in age 30-60 years old amount to 10 people divided 5 people for intervention group and 5 people for control group. Based on the research results have significant different among patient of diabetes mellitus type 2 who consume coffee and patient of diabetes mellitus type 2 with placebo.
AKTIVITAS ANTIOKSIDAN EKSTRAK METANOL KULIT JERUK SIAM BANJAR (Citrus reticulata) Dwi Rizki Febrianti; Novia Ariani; Rakhmadhan Niah; Rahmatul Jannah
Jurnal Insan Farmasi Indonesia Vol 2 No 1 (2019)
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

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Abstract

Radikal bebas merupakan faktor yang menyebabkan terjadinya berbagai penyakit degeneratif. Penyakit degeneratif telah menjadi penyebab kematian terbesar di Indonesia. menghindari dampak negatif dari radikal bebas maka diperlukan antioksidan. Kulit jeruk siam banjar diekstraksi menggunakan metode maserasi, proses ekstrasksi dengan pelarut metanol. Tujuan dari penelitan adalah untuk mengetahui aktivitas antioksidan ekstrak metanol kulit jeruk siam banjar meggunakan metode DPPH. Metode yang digunakan spektrofotometer UV-Visible, dimana hasil dari absorbansi dimasukkan dalam rumus persen aktivitas antioksidan. Setelah didapatkan persen aktivitas antioksidan dilakukan perhitungan IC50 menggunakan regresi linier Hasil penelitian menunjukkan bahwa kulit jeruk siam banjar mengandung Antioksidan yaitu 175 ppm (14,01%), 200 ppm (22,25%), 225 ppm (31,73%), 250 ppm (45,32%), 275 ppm (54,53%) dengan nilai IC50 sebesar 264 ppm.
DAYA HAMBAT BAKTERI Staphylococcus aureus EKSTRAK DAUN GAHARU (Aquilaria malea L.) SEBAGAI ANTIBAKTERI Abdul Rahman Wahid; Dzun Haryadi Ittiqo
Jurnal Insan Farmasi Indonesia Vol 2 No 1 (2019)
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

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Abstract

Aquilaria malea L. are spread naturally in several countries, one of them in Indonesia. This plant has many benefits ranging from stems and leaves. Agarwood leaves contain various antibacterial compounds such as flavonoids, alkaloids, saponins and tannins. Staphylococcus aureus is a facultative anaerobic gram-positive bacterium which is the cause of infection in wounds in the form of abscesses or a collection of pus. The study aims to determine the inhibitory strength of Staphylococcus aureus bacteria extract of aloes leaves as anti-bacterial. This type of research is laboratory experimental through the disc diffusion method. The concentration of agarwood leaves used is 300, 350, 400, and 450 mg/ml and positive control Amoxicillin. Data were analyzed using One Way Annova. The results of this study showed the average inhibition zone of agarwood leaf extract against Staphylococcus aureus bacteria with agarwood leaf extract concentration of 300 mg/ml (15.33 ± 2.51), concentration of 350 mg/ml (16.33±2.25), concentration of 400 mg/ml (20.5± 2.17), concentration of 450 mg/ml (21.17±3.32) and inhibition zone of Amoxicillin (37±0.00). This concluded that agarwood leaf extract had inhibitory potential for the growth of Staphylocccus aureus bacteria. The biggest inhibition power of Staphyloccus aureus growth was 450 mg/ml (21.17 ± 3.32).
GAMBARAN POLA PENGGUNAAN ANTIBIOTIK PADA PASIEN COMMON COLD ANAK DI INSTALASI RAWAT JALAN RSUD DR. H. MOCH. ANSARI SALEH BANJARMASIN Nazhipah Isnani; Muliyani Muliyani
Jurnal Insan Farmasi Indonesia Vol 2 No 1 (2019)
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

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Abstract

Common cold is infection from a virus. Inflammatory mucous membranes produce a lot of mucus so that the nose becomes blocked and difficult to breathe. This study aims to determine the characteristics of the use of antibiotics for common cold child and determine to the pattern of the use antibiotic of patients in hospital outpatient installations at RSUD dr. H. Moch. Ansari Saleh Banjarmasin. This research was an observational or non-experimental study with a descriptive design, using retrospective data that was collected patient medical record data. The results of this study ware based on the characteristics of children age research subjects who are most afflicted with common cold disease from the age of 1-5 years, based on the sex of boys are more often attacked by common cold than girls, antibiotics are most commonly used in common cold patients child is second generation Cepalosporin, Cefadroxil.
PENENTUAN KADAR FLAVONOID TOTAL PADA EKSTRAK ETANOL DAUN ANDONG MERAH DAN DAUN ANDONG HIJAU Dian Kartikasari; Adhisty Kharisma Justicia; Paula Endang
Jurnal Insan Farmasi Indonesia Vol 2 No 1 (2019)
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

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Determination of flavonoid content in the ethanol extract of red andong leaves and green andong leaves, which was determined by the colorimetric method using Uv-Vis spectrophotometry, aims to determine the flavonoid levels in the ethanolic extract of red andong leaves and green andong leaves. nm, the total flavonoid content is calculated by linear regression equation y = 0.00757x + 0.0324 with the coefficient of relation r² = 0.997842544. Determination of total flavonoid content was carried out by spectrophotometry based on the ability of flavonoids to form complexes with AlCl3. The flavonoid content obtained from the ethanol extract of red andong leaves is 0.329% and green andong ethanol extract is 0.4354%.
PENENTUAN NILAI SPF (SUN PROTECTION FACTOR) KRIM EKSTRAK ETANOL BUNGA TELANG (CLITORIA TERNATEA) SECARA IN VITRO MENGGUNAKAN METODE SPEKTROFOTOMETRI Dian Puspitasari; Diah Pratimasari; Disa Andriani
Jurnal Insan Farmasi Indonesia Vol 2 No 1 (2019)
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

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Indonesia is a tropical country with high sun exposure. High sun exposure can cause several problems with the skin, ranging from reddish skin, pigmentation, and even for a long time can cause cancer risk. One way to reduce the negative impact of sun exposure by using sunscreen. Telang flowers are rich in bioactive compounds such as phenolic compounds, especially flavonoids, which have the potential to be used as sunscreens. This study aims to determine the optimal concentration of telang flower extract on sunscreen cream based on physical properties and SPF values.Telang flowers are extracted macerated using 70% ethanol, then the obtained Telang flower extract (EBT) is formulated into a sunscreen cream with various concentrations. Various EBT concentrations on sunscreen creams were tested for physical stability and their effectiveness based on SPF values. The data obtained were analyzed statistically by ANOVA using the T-test with a confidence level of 95%. From this study, the optimum concentration of telang flower extract was found to be 5% contained in Formula III sunscreen cream.
POLA PERSEPAN ANTIBIOTIK PADA PASIEN PNEUMONIA DI POLI ANAK RSUD DR. H. M. ANSARI SALEH BANJARMASIN TAHUN 2017 Muhammad Zaini; Muliyani Muliyani; Jhudi Bonosari Soediono; Elisa Destiana
Jurnal Insan Farmasi Indonesia Vol 2 No 1 (2019)
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

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Abstract

Pneumonia was a respiratory infection. Pneumonia was most often caused by bacterial, viral or mycoplasmic infections. The choice of therapy for pneumonia sufferers was generally given antibiotics. The purpose of this study was to determine the pattern of antibiotic use of pneumonia in pediatric patients in outpatient hospitals of dr. H. M. Ansari Saleh. The study was descriptive, data collection was carried out retrospectively in pneumonia patients who met the inclusion criteria was 52 samples. Data was taken from January to December 2017 through medical records. The results showed that pneumonia patients suffered the most from men by 26 cases (50%) and women by 26 cases (50%), based on the age of the most aged 1 - 12 months as many as 25 patients (48.07%). The use of antibiotics based on the selection of the most widely used groups is the third generation cephalosporins as many as 42 patients (80.76%), penicillin group as many as 6 patients (11.53%), the second generation cephalosporins as many as 4 patients (7.69%). The type of antibiotic that was often used is Cefixime as many as 46 users (88.46%), Amoxicillin as many as 6 users (11.53%), Cefadroxyl as many as 4 users (7.69%).
GAMBARAN PENGGALIAN DAN PEMBERIAN INFORMASI OBAT ATTAPULGITE DI APOTEK KECAMATAN BANJARMASIN TIMUR Ratih Pratiwi Sari; Erna Prihandiwati
Jurnal Insan Farmasi Indonesia Vol 2 No 1 (2019)
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

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The practice of self-medication in cases of diarrhoea is important to do, including extracting and providing correct drug information. The purpose of this study was to determine the description of extracting and providing information by pharmacists on patients who bought attapulgite drugs at the pharmacy in the East Banjarmasin area. This study is a non-experimental study conducted in March until July 2018, with samples used by all pharmacy staff working in pharmacies in the East Banjarmasin area. The results of this study indicate that the profile of attapulgite drug extraction information includes the identity of the patient (25%), frequency of bowel movements (16.66%), other symptoms (0%), what drugs have been used to treat diarrhea (0 %), other drugs being used (4.16%), patient history (0%), allergy history of patients (0%), non-pharmacological actions to treat diarrhea (0%), history of diarrhea (0%) and other questions (8.33%). The results of the profile research giving information show that the method of using the drug (25%), drug interactions (0%), side effects (0%), and frequency of use (8.33%).

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