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Fitria Megawati
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Jalan Kamboja No.11A, Denpasar Utara, Denpasar, Bali, Indonesia
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INDONESIA
Usadha
Published by Universitas Mahasaraswati
ISSN : -     EISSN : 29632161     DOI : https://doi.org/10.36733/usadha.v2i2
Core Subject : Health, Science, Agriculture,
Agriculture, Biological Sciences & Forestry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health
Usadha: Jurnal Integrasi Obat Tradisional, bertujuan untuk mendorong integrasi Obat Tradisional ke dalam sistem pelayanan kesehatan modern dalam bentuk pertukaran informasi ilmiah baik di kalangan peneliti, praktisi obat tradisional dan tenaga medis, pemegang kebijakan, industri dan stakeholder lainnya, dalam upaya pengembangan obat tradisional untuk masyarakat. Usadha menerima berbagai macam hasil penelitian dari berbagai bidang ilmu baik dalam bentuk artikel original, artikel review, maupun komunikasi singkat yang berkaitan dengan upaya untuk mendorong integrasi dan pengembangan obat tradisional mulai dari hulu hingga ke hilir, yang dapat meliputi namun tidak terbatas pada: 1) eksplorasi dan identifikasi bahan obat tradisional; 2) identifikasi zat aktif dari bahan alam; 3) pembuktian ilmiah khasiat dan keamanan obat tradisional baik preklinis maupun klinis; 4) pengembangan teknologi ekstraksi dan isolasi senyawa bahan alam; 5) teknologi produksi dan penghantaran obat berbasis bahan alam serta kosmetika herbal; 6) pengembangan produk nutrasetika dari bahan herbal; 7) sistem pelayanan obat tradisional di klinik dan komunitas; 8) kebijakan di bidang obat tradisional, konservasi dan budidaya tanaman obat tradisional; dan lainnya yang dalam lingkup obat tradisional. Usadha diterbitkan oleh Fakultas Farmasi Universitas Mahasaraswati Denpasar, dengan jumlah terbit 3 kali dalam setahun pada bulan April, Agustus, dan Desember.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 10 Documents
 1 
Search results for , issue "Vol 2 No 1 (2022): Usadha: Jurnal Integrasi Obat Tradisional" : 10 Documents clear
Manfaat dan Pengembangan Teknologi Umbi Porang (Amorphophallus muelleri Blume) melalui Metode Pengeringan Putu Ayu Viona Serapin Putri
Usadha Vol 2 No 1 (2022): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v2i1.3424

Abstract

Porang tubers are one of the most popular plant cultivations in the international market. The benefits and advantages of porang tuber cultivation make porang tubers one of the strengths to be able to reduce imports. The benefits of this cultivation will certainly be felt by farmers. Because of the great benefits felt, it would be very appropriate if porang tubers would be strongly associated with technology, especially in the drying method. This study aims to be able to show descriptively the method of drying porang tubers from conventional things that still depend on solar heat to technology-based to the creation of a drying machine. The application of technology will certainly facilitate the community in accelerating the production of porang tubers. Optimization to achieve time efficiency is certainly the biggest advantage. Until finally the factors inhibiting production will be minimized. Key note: Porang tubers, drying machine, solar heat
Potensi Sirih (Piper betel L.) Sebagai Anti-Asma Maria Malida Vernandes Sasadara; Luh Putri Dianti Laksmi; Ni Luh Gede Erica Fridayana; Anak Agung Vivi Noviyanti; Ni Putu Arie Leony Kertita; Ni Kadek Jessica Agustin
Usadha Vol 2 No 1 (2022): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v2i1.3510

Abstract

Asma merupakan peradangan saluran napas kronik dengan indikasi adanya mengi, batuk, dan rasa sesak yang timbul berulang .Studi epidemiologi menunjukkan hubungan yang kuat antara asma dan infeksi dengan patogen pernapasan, termasuk virus pernapasan umum seperti rhinovirus, human respiratory syncytial virus, adenovirus, coronavirus dan virus influenza, serta bakteri dan jamur. Salah satu upaya dalam pengobatan asma dapat menggunakan tanaman obat seperti tanaman sirih (Piper betel L.). Sirih menunjukan beberapa aktivitas farmakologis seperti antioksidan, antibakteri dan antihistamin sehingga berpotensi untuk digunakan dalam terapi asma. Tujuan penulisan artikel review ini untuk mempelajari aktivitas tanaman sirih sebagai tanaman obat dalam terapi asma. Metode yang digunakan dalam penyusunan artikel review ini yaitu studi literatur melalaui beberapa basis data yang kemudian diskrining dengan beberapa kriteria. Hasil review menunjukan bahwa kejadian asma berkaitan erat dengan stress oksidatif yang terbentuk karena tingginya radikal bebas. Kandungan senyawa fenolik seperti chatecol dan allylpyrocatecol pada tanaman sirih berperan sebagai antioksidan yang menghambat timbulnya stress oksidatif. Selain itu tanaman sirih juga menunjukan aktivitas antibakteri terhadap bakteri pneumonia. Ekstrak etanolik dan minyak atsiri daun sirih juga secara signifikan menunjukan aktivitas penghambatan bronkospasme yang diinduksi histamine. Berdasarkan hasil dapat disimpulkan bahwa tanaman sirih dapat digunakan sebagai kandidat alternatif untuk pengembangan obat dalam penatalaksanaan asma.
Identifikasi Senyawa Flavonoid dan Aktivitas Antioksidan Ekstrak Etanol Buah Dewandaru (Eugenia uniflora L.) Puguh Santoso; Fitria Megawati; Ni Wayan Cintya Purnama Sari; Ni Kadek Linda Paramita
Usadha Vol 2 No 1 (2022): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v2i1.4588

Abstract

Indonesia is a country with abundant natural wealth. Almost all kinds of plants can grow in this country. Most have been used since ancient times to treat various diseases. One of the efficacious plants used as medicine is the Dewandaru fruit (Eugenia uniflora L.). This study aims to identify the presence of flavonoid compounds in the Dewandaru fruit (Eugenia uniflora L.) and test the in vitro activity of the ethanol extract of the Dewandaru fruit. Dewandaru fruit extract (Eugenia uniflora L.) was prepared using the maceration extraction method with 96% ethanol solvent. The extraction process was carried out three times. The extract obtained was concentrated in a rotary evaporator at 40-45 °C and then dried in an oven at 40°C. The extracts obtained were identified by means of ultraviolet visible spectrophotometry thin-layer chromatography. obtained showed a positive reaction in the pre-test of flavonoids seen from the separation of red and from the separation of orange stains on thin-layer chromatography. The results of the in vitro test for the antioxidant activity of the ethanol extract of Dewandaru fruit showed an IC50 activity of 53.44 ppm.
Pengaruh Pelarut dan Metode Ekstraksi terhadap Kandungan Metabolit Sekunder dan Nilai IC50 Ekstrak Umbi Bit (Beta vulgaris L.) Maria Malida Vernandes Sasadara; I Gede Wiranata
Usadha Vol 2 No 1 (2022): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v2i1.5277

Abstract

Beetroot (Beta vulgaris L.) contains phenolic, flavonoid, and tannin, as well as anthocyanin and betacyanin pigments which are strong antioxidant compounds. The extraction process is needed to collect the phytochemical content in plant samples. Several factors affect the extract's phytochemical content, including the extraction method and solvent. This research was conducted to determine the effect of maceration and ultrasonic extraction methods and solvents on the levels of phenol, flavonoids, tannins, anthocyanins, and the IC50 value of beetroot extract. This research is experimental laboratory research. Extraction of beetroot was carried out by maceration (M) and ultrasonic (U) using water solvents (MA & UA), 50% ethanol (ME50 & UE50), and 96% ethanol (ME96 & UE96). Phytochemical quantification was carried out on phenols, flavonoids, tannins, and anthocyanins levels. The antioxidant activity test was carried out using the DPPH method to obtain the IC50 value. Data analysis was performed using one-way analysis of variance (ANOVA) with a 95% confidence level. The results showed that the selection of extraction methods and solvents affected the concentration of phenols, flavonoids, tannins, and anthocyanins, as well as the antioxidant activity of the extracts. The UE96 extract produced the highest concentrations of phenols, flavonoids, tannins, and anthocyanins compared to other extracts, with the lowest IC50. All results showed significant differences (p<0.05) except for the anthocyanin content produced by ME96 and UA extracts. In conclusion, the ultrasonic method with 96% ethanol solvent is considered the best method for extracting beetroot (Beta vulgaris L.), producing extract with good antioxidant activity and high levels of phenol, flavonoids, tannins, and anthocyanins.
Analisis Angka Lempeng Total Minyak Balur Kombinasi VCO dan Cabai Jawa (Piper retrofractum Vahl.) dengan Variasi Suhu Pemanasan Luh De Cintya Kartika Sari; Dewa Ayu Ika Pramitha; I Gusti Agung Ayu Kusuma Wardani
Usadha Vol 2 No 1 (2022): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v2i1.5520

Abstract

Balur oil combined with VCO and Javanese long pepper is a liquid herbal ingredient obtained from the fruit of the Javanese long pepper (Piper retrofractum Vahl.) with the addition of coconut oil (Cocos nucifera). This study was conducted to analyze the microbiological quality of VCO and Javanese long pepper combined balur oil to determine the safety of combined VCO and Javanese long pepper balur oil using the Total Plate Count (ALT) method. Balur oil combined with VCO and Javanese long pepper was made into 3 samples with different heating temperatures. Sample 1 is balur oil with a heating temperature of 40°C, sample 2 is balur oil with a heating temperature of 50°C, and sample 3 is balur oil with a heating temperature of 60°C. The results showed that the three samples of balur oil combined with VCO and Javanese long pepper with variations in heating temperature had different total microbial values, namely 3, 0, and 6 CFU/mL. Sample 1 had a total microbial value of 3 CFU/mL, sample 2 had a total microbial value of 0 CFU/mL, and sample 3 had a total microbial value of 6 CFU/mL. The three samples of VCO and Javanese long pepper combination oil had a total safe microbial value because they had not exceeded the maximum allowable microbial contamination limit according to BPOM No. 32 of 2019, namely 107 colonies/mL.
Review: Pemanfaatan Tanaman sebagai Fitoterapi pada Diabetes Mellitus Ni Luh Kade Arman Anita Dewi; Putu Nimas Diyah Prameswari; Erna Cahyaningsih; Fitria Megawati; Ni Putu Dewi Agustini; Debby Juliadi
Usadha Vol 2 No 1 (2022): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v2i1.5562

Abstract

Diabetes is a chronic disease that occurs due to high levels of sugar in the blood, this can occur when the pancreas does not produce enough insulin (a hormone that regulates blood sugar or glucose), or when the body cannot effectively use the insulin it produces. Management of DM patients can be carried out with non-pharmacological and pharmacological therapies. The method used in the journal review was to search for the keyword "diabetes mellitus herbal medicine" for clinical studies on plant-derived products for the treatment of diabetes mellitus. Search terms included “phytotherapy”, “phytochemicals”, “medicinal plant products”, “herbal medicine”, and “diabetes mellitus”. Involving plant-derived compounds and pigmentation as outcome measures were included. In this review article, 30 journals were collected from which the objectives and results of the research in the journal were obtained. The goal is as an alternative management treatment to control blood sugar levels. For some of the compounds we discuss, among others: Flavonoids, Allicin, Lectins, Alkaloids, Andrographolid, Curcumin, Cinnamaldehyde, peptides, Phenolics, Tannins.
Formulasi dan Evaluasi Mutu Fisik Lip balm dari Ekstrak Kulit Buah Hylocereus lemairei dengan Variasi Konsentrasi Cera Alba Ni Made Dharma Shantini Suena; Ni Putu Ocha Indira Intansari; I Gede Made Suradnyana; Ni Nyoman Yudianti Mendra; Ni Putu Udayana Antari
Usadha Vol 2 No 1 (2022): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v2i1.5583

Abstract

Red dragon fruit skin (Hylocereus lemairei) contains flavonoid compounds (polyphenols), and vitamins C and E which play the main role as antioxidants, so they are good for moisturizing, nourishing, and maintaining skin health. Lip balm is a cosmetic preparation with main components such as waxes, fats, and oils from natural or synthesized extracts to prevent dryness by increasing lip moisture. The stability of preparation is very important in maintaining the physical quality of the preparation until it reaches the consumer. This study aims to determine the concentration of Cera alba as a stiffening agent needed to produce lip balm preparations of red dragon fruit skin extract (Hylocereus lemairei) with good physical quality. The response observed was the physical quality of the lip balm preparation which included organoleptic, homogeneity, pH, adhesion, and mechanical strength of the lip balm. Data analysis was carried out descriptively. This research begins with the extraction process of red dragon fruit skin using an ultrasonic wave-assisted maceration method using 96% ethanol and 1% HCl. In this study, a lip balm formulation was made from red dragon fruit peel extract with various concentrations of Cera alba 5% (F1), 10% (F2), and 15% (F3) as a stiffening agent. The resulting preparations were stored for 28 days, and their physical quality was observed. The results showed that lip balm preparations F3 produced good physical quality of lip balm preparations during storage. Dragon fruit peel extract can be properly formulated using Cera alba at a concentration of 15% to become a lip balm preparation that has high-quality physical characteristics and has the potential to be developed into a cosmetic preparation that is able to maintain skin moisture, especially the lips.
Efektivitas Pengobatan Tanaman Herbal dan Terapi Tradisional untuk Penyakit Tulang dan Persendian Erna Cahyaningsih; Ni Luh Kade Arman Anita Dewi; Ni Nyoman Wahyu Udayani; Ni Kadek Sari Dwipayanti; Fitria Megawati
Usadha Vol 2 No 1 (2022): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v2i1.5596

Abstract

Bones are the body's framework that causes the body to stand upright, where the muscles are attached to allow the passage of blood vessels, where the bone marrow and nerves protect soft tissues. Traditional medicine is an effort to treat or treat other ways outside of medical science or nursing science. Indonesia is one of the countries that have the potential to develop medicinal plant cultivation and use it as an alternative treatment. This study aims to determine the effectiveness of herbal medicine and traditional therapy for bone and joint diseases. This study uses the method of literature study. The results showed that traditional herbal therapy for ball compresses, lemongrass warm compresses, cinnamon warm compresses, lavender aromatherapy warm water flower compresses, bangle rhizome compresses, and ginger warm compresses can be used for bone and joint diseases. Where there are compounds in herbal plants that have effectiveness as traditional medicine and therapy for bone and joint diseases, namely flavonoids, quercetin, curcumin, 6-gingerol and shogaol, alkaloids, steroids, and saponins.
Review Artikel: Trend Pemilihan Sediaan Kosmetik Herbal pada Kulit Wajah I Putu Satria Antara; Fitria Megawati; Ni Luh Kade Arman Anita Dewi
Usadha Vol 2 No 1 (2022): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v2i1.5661

Abstract

Cosmetics are ingredients or preparations intended for use on the outside of the human body (epidermis, hair, nails, lips and external genital organs) or teeth and oral mucous membranes. This article aims to look at the potential of herbal cosmetics used on facial skin. The thing that becomes an important value in this review article is how the trend of product forms is favored by the public. The type of research method used in this article review is using a review article study, by collecting data derived from articles in journal form regarding the topic of using herbal cosmetic preparations on the face in the last 5 years. The distance of the last 5 years is taken because it can still be considered as good data to use. The most widely used herbal cosmetic dosage forms in the last 5 years are cream preparations. Cream preparations were chosen because of their ease of use on the face compared to other dosage forms
Obat Herbal Berbasis Bukti Untuk Hepaprotektor: Obat Herbal Berbasis Bukti Untuk Hepaprotektor Ni Putu Dewi Agustini; Ni Luh Kade Arman Anita Dewi; Fitria Megawati; Ratna Wulandari
Usadha Vol 2 No 1 (2022): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v2i1.5925

Abstract

Liver damage can occur due to infection, viruses, drug use, and the environment. Paracetamol is a drug that has analgesic and antipyretic effects, but on the other hand the use of paracetamol in excessive doses (15/day) can cause liver damage. This can occur because the process of paracetamol metabolism in the liver forms a reactive metabolite known as N-acetyl-pbenzoquinonemine (NAPQI). The hepatoprotective mechanism can be seen from the ability of Ichnocarpus frutescens to ward off free radicals formed from the process of lipid oxidation due to the reactive metabolite of paracetamol, namely NAPQI. The method used is a literature review which is a systematic, explicit and reproducible method for carrying out identification, evaluation and synthesis of research works and ideas that have been produced by researchers and practitioners. The data base used is National and International Journal Websites such as Google Scholar.

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