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INDONESIA
Jurnal Kedokteran Diponegoro
Published by Universitas Diponegoro
ISSN : -     EISSN : 25408844     DOI : -
Core Subject : Health,
Medicine & Pharmacology
JKD : JURNAL KEDOKTERAN DIPONEGORO ( ISSN : 2540-8844 ) adalah jurnal yang berisi tentang artikel bidang kedokteran dan kesehatan karya civitas akademika dari Program Studi Kedokteran Umum, Fakultas Kedokteran, Universitas Diponegoro Semarang dan peneliti dari luar yang membutuhkan publikasi . JURNAL KEDOKTERAN DIPONEGORO terbit empat kali per tahun. JURNAL KEDOKTERAN DIPONEGORO diterbitkan oleh Program Studi Kedokteran Umum, Fakultas Kedokteran, Universitas Diponegoro Semarang.
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Articles 15 Documents
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Search results for , issue "Vol 10, No 4 (2021): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)" : 15 Documents clear
THE RELATIONSHIP BETWEEN AWARENESS AND KNOWLEDGE LEVEL OF CLINICAL DENTAL STUDENTS ABOUT ORAL CANCER DISEASE Stefani Marlene Tarius; Tira Hamdillah Skripsa; Diah Rahayu Wulandari
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 10, No 4 (2021): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v10i4.30151

Abstract

Background: Oral cancer is the sixth most common type of cancer with two out of three cases occurring in developing countries. As clinical dental students, knowledge and awareness about oral cancer should also be improved with the aim of helping them as future dentists to be more ready to act immediately in prevention phase and early diagnosis of oral cancer.Objective: This study aims to analyze the relationship between the level of knowledge and the level of awareness of dental students about oral cancer.Methods: An observational analytic study with a cross sectional study design. A total of 91 clinical dental students participated in this study. Oral cancer awareness and knowledge level were measured using a pre-validated questionnaire. Spearman’s rho correlation test was used to determine the association between oral cancer awareness and knowledge level of clinical dental students.Results: Out of 91 clinical dental students, 61 (67%) students got excellent-graded awareness and 57 (62,6%) students got good-graded knowledge. Spearman rho correlation test showed oral cancer awareness were significantly associated (p=0,007) with oral cancer knowledge level. Significant positive linear correlations (r=0,279) between oral cancer awareness and knowledge level were also observed from the study results.Conclusion: Clinical dental students’ oral cancer awareness and knowledge level are significantly associated.
MELATONIN CAN NOT SIGNIFICANTLY REDUCE BLOOD SUGAR LEVELS Christiana Rinalda; Taufik Eko Nugroho; Lusiana Batubara; Asih Budiastuti
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 10, No 4 (2021): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v10i4.29491

Abstract

AbstractBackground: Burn are trauma that can cause local and systemic damage including hypermetabolism, inflammation, and hyperglicemia. Stress Induced Hyperglycemia (SIH) occurs by increasing gluconeogenesis and insulin resistance. Both of these are mediated through an increase in regulated stress hormones and proinflammatory cytokines. Melatonin has been proposed as a burn supportive therapy that may prevent oxidative damage and inhibit excessive inflammatory responses.Aim: Proving the effects of melatonin supplementation on blood glucose level in male Wistar rats with burn injury.Methods: This research was an experimental with randomized control group pre-post test design. Twelve healthy male Wistar rats were included and divided into two groups, control and experimental group. Each rat was induced 30% burn injury under anesthesia. Rats in control group were given placebo, while rats in experimental group were treated with melatonin i.p at 0, 8 and 16 hours after burn injury. Blood samples were collected from the retroorbital sinuses at 0, 3, and 24 hours. Data were analyzed statistically by Paired t-Test and Independent t-Test. Results: In male Wistar rats with third degree burns given placebo, blood sugar levels significantly increase in 0-3 hours (p=0.006)  and 0-24 hours (p=0.037). Meanwhile, in male Wistar rats with third degree burns given melatonin, blood sugar levels did not change significantly in 0-3 hours (p=0.470), 0-24 hours (p=0.286), dan 3-24 hours (p=0.833). Conclusions: Melatonin administration can not significantly reduce blood sugar levels.Keywords: Burn, burn injury, blood glucose level, melatonin.
DIFFERENCES IN OCULAR SURFACE DISEASE INDEX SCORE IN PATIENTS BEFORE AND AFTER COMBINATION OF PHACOEMULSIFICATION AND TRABECULECTOMY. Avri Panggabean; Riski Prihatningtias; Arief Wildan; Maharani Cahyono
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 10, No 4 (2021): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v10i4.30027

Abstract

AbstractBackground: Dry eye is a disturbance on the surface of the eyeball marked by the loss of tear layer homeostasis, which can occur due to the instability and hyperosmolarity of tear film, inflammation or damage to the surface of the eyeball, and neurosensory abnormalities. Some surgical interventions related to the anterior part of the eye can cause symptoms of dry eye, one of which is facotrabeculectomy is a combination of surgical intervention performed in glaucoma patients with cataracts. One examination to evaluate the symptoms of dry eye is to use the Ocular Surface Disease Index (OSDI) questionnaire.Objective: This study aims to observe the difference in Ocular Surface Disease Index (OSDI) scores in patients before and after surgery combined with phacoemulsification and trabeculectomy.Methods: Analytic observational research with one group pretest and posttest research design. With a large sample of 18 respondents who were evaluated by the OSDI questionnaire in patients before and two weeks after facotrabeculectomy. Hypothesis testing with a paired T-test.Results: The results showed that before the surgery for facotrabeculectomy, the average OSDI score was 50.4628 ± 7.9429. After two weeks postoperatively the results of the study showed the average OSDI score was 58.7972 ± 7.7155. Hypothesis testing showed that OSDI scores before and after facotrabeculectomy surgery were significant differences (p = 0.001 / p <0.05).Conclusion: There were significant differences in OSDI scores in patients before and after facotrabeculectomy surgery.
CHARACTERISTIC OF MAMMOGRAPHY COMPARED WITH HISTOPATHOLOGY RESULT AT RSUP DR. KARIADI Molly Inta Sari; RR Lydia Purna Widyastuti Setjadiningrat Kuntjoro; Edmond Rukmana Wikanta; Sukma Imawati
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 10, No 4 (2021): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v10i4.30166

Abstract

AbstractBackground: Breast tumors are common lesions found in women.[1] Mammography is Food and Drugs Administration (FDA) approved modality for screening and diagnosing breast tumor.[2,3] Aim: To know the characteristic and comparison of mammography results with histopathology diagnosis as the gold standard in breast tumor patients at RSUP Dr. Kariadi. Methods: This research used the diagnostic test method. Data were taken from medical records in RSUP Dr. Kariadi, Semarang from 2017 to 2019 with sa consecutive sampling method. The collected samples were 55 mammography imaging. Next, the data were described as frequency distribution and percentages, and then the diagnostic test values were counted. Result: Benign breast tumor in RSUP Dr. Kariadi was found in 40-50 years old patients with 77,8% oval-shaped and 72,2% circumscribed margin mass seen in the mammogram, while breast cancer was found in >50 years old patients with 57,1% irregular-shaped and 54,3 spiculated margin mass seen in the mammogram. Mammography in RSUP Dr. Kariadi has 89% sensitivity, 89% specificity, 94% positive predictive value, 81% negative predictive value, and 89% accuracy. Conclusion: Benign breast tumor in RSUP Dr. Kariadi mostly found in 40-50 years old patients with oval-shaped and circumscribed margin mass seen in the mammogram, while breast cancer is mostly found in >50 years old patient with irregular shape and spiculated margin mass seen in the mammogram. The diagnostic test score of mammography in RSUP Dr. Kariadi is high.
FACTORS RELATED TO ECTOPIC PREGNANCY IN RSUD R.A KARTINI JEPARA Muhammad Fikri Hanif Raza Pradana; Yuli Trisetiyono; Bambang Hariyana; Muhammad Besari Adi Pramono
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 10, No 4 (2021): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v10i4.30010

Abstract

Background: Ectopic Pregnancy (EP) is a pregnancy outside the womb that ends with a rupture. Bleeding is one of the causes of the increase in Maternal Mortality Rate (MMR) by 24.5% in Central Java Province in 2017. Research to determine the factors associated with the occurrence of EP needs to be known so that the incidence of EP and MMR in Indonesia can be controlled.Purpose: This study aimed to see the incidence of EP and analyzing the relationship between age and parity with the incidence of EP in RSUD R.A Kartini Jepara.Methods: This study used an analytic observational method with a case-control research design. Sampling was done by consecutive sampling method. A total of 83 samples met the inclusion criteria, which were divided into 51 pregnant women with EP and 32 pregnant women without EP. Data were analyzed using descriptive test and Chi-square test. The factors assessed were age and parity. Other variables contained in medical records are included in the form of descriptive data.Results: The incidence of EP in RSUD R.A Kartini Jepara was 0.4% in 2017, 0.5% in 2018, and 0.3%  in 2019. In EP patients, it was found that 54.9% of patients had an education level of junior high school, 58.8% of patients had a salpingectomy procedure, 92.1% of patients whose EP location was in the tube and 60.7% of patients needed inpatient services for >4 days. The results of the bivariate analysis using the Chi-square test showed a significant relationship between parity (p = 0.029) and the incidence of EP (p <0.05). Meanwhile, age (p = 0.897) did not show a significant relationship with the incidence of EP (p> 0.05).Conclusion: The incidence of EP in RSUD R.A Kartini Jepara in was 0.4% in 2017, 0.5% in 2018, and 0.3%  in 2019. There is a relationship between parity and the incidence of EP. Meanwhile, age is not related to the incidence of EP in RSUD R.A Kartini Jepara. Keywords: Ectopic Pregnancy, Age, Parity
EFFECT OF COUNSELING ON KNOWLEDGE ATTITUDE AND BEHAVIOR OF TEXTILE INDUSTRY WORKERS ABOUT NIHL Armabar Dwipantara Sasongko; Dwi Marliyawati; Kanti Yunika; Zulfikar Naftali
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 10, No 4 (2021): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v10i4.30138

Abstract

Background: Noise Induce Hearing Loss (NIHL) is a work accident which has a high incidence rate of workers ini the manufacturing industry nowadays. Attitudes and obedience behavior of manufacturing workers in using personal noise protective equipments are influenced by their knowledge about NIHL. Providing information such as health education periodically is needed to increase worker’s knowledge to change their attitudes and behaviors in order to obey safety regulations and using personal noise protective equipments.Objective: This study examines the effect of providing health counseling on the knowledge, attitudes, and behaviors of textile industry workers regarding noise induce hearing loss.Methods: This research method used quasi-experimental research method, with a one group pretest-posttest as design approach. Intervention of this research was a health counseling and the research instruments were leaflets, modules, and lectures about noise induced hearing loss. The subjects of this study were 35 workers of textile factories. Consecutive sampling were used to get subjects. Data on the level of knowledge, attitudes, and behavior were obtained through questionnaires before intervention and two weeks after the intervention was carried out. This research was located in one of the textile factories in Semarang Regency in 2020. Statistical analysis used Wilcoxon test, Fisher test, and Kolmogorov-Smirnov test.Results: The result of this research show that there was an increase in the mean score of subjects’s knowledge, attitudes and behavior. Statistical analysis show that that there is a significant differences between knowledge scores (p value = 0,000), attitudes scores (p value = 0,000), and behavior scores (p value = 0.024) before and after being given health education.Conclusion: The mean score of knowledge, attitudes and behavior of workers after being given information about noise induced hearing loss is higher than the average score of knowledge, attitudes and behavior of workers before being given a counseling.
PREOPERATIVE CARDIAC REHABILITATION IN A 28 YEARS-OLD WOMAN WITH VALVULAR HEART DISEASE Sri Hastuti Barata; Erna Setiawati; Endang Ambarwati
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 10, No 4 (2021): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v10i4.29289

Abstract

Background: Valvular heart disease (VHD) is one third of all heart disease. In industrialized countries, the prevalence is estimated at 2,5% and in developing countries is between twenty to thirty cases per-1000 people. VHD presents a huge health burden worldwide. If heart failure has occured, surgery is the treatment of choice. Cardiorespiratory fitness declined in post-surgical patients. Preoperative cardiac rehabilitation is considered to be able to increase the cardiorespiratory fitness baseline so that postoperative outcomes are better.Case Presentation: We reported 28 years-old female with severe MS and MR as well as mild TR with symptoms dyspnea on effort which improves with rest. She was the candidate for mitral valve replacement. She was given a 14-days preoperative cardiac rehabilitation program including breathing exercise by pursed lips breathing, effective cough exercise, range of motion exercise, ankle pumping exercise, endurance exercise based on the result of the 6 minutes walking test (6MWT) and inspiratory muscle training (IMT) using threshold IMT. Conclusion: Preoperative cardiac rehabilitation program improved pulmonary functional capacity, cardiorespiratory fitness and functional activity.Keyword: valvular heart disease, cardiac rehabilitation, pulmonary functional capacity, cardiorespiratory fitness.
SCREENING OF HEARING DISORDER IN CHILDREN AGED 13-14 YEARS IN TEGAL Ilma Mufidatul Aufa; Yanuar Iman Santosa; Dwi Marliyawati; Zulfikar Naftali
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 10, No 4 (2021): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v10i4.30021

Abstract

ABSTRACT Background: Hearing loss is an impairment or inability of hearing, which is a threshold value of hearing more than 40 decibels (dB) in adults or more than 30 decibels (dB) in children. Hearing loss can result in decreased learning achievement at school, problems in communication, psychological problems, and if complications have occurred, it will cost more for the treatment.Aim : This study aims to determine characteristics of hearing loss in children aged 13-14 years.Methods : This study is a descriptive study with a total sample of 61 students taken by simple random sampling method from a total of 599 students aged 13-14 years.  The data were obtained from the questionnaires and physical examination of the ear. Simple auditory function was examined using a tuning fork.Results : The results in this study indicate that the largest group is 14 years old and male gender (52%).  It was found that 13 students (21%) had a tympanic membrane and 1 student (2%) had a tympanic membrane perforated in the right ear. In the hearing function, it was found that 1 student with a conductive type disorder.  From the questionnaire on the risk factors for hearing loss, there were the use of cotton buds for 53 students (87%), routine checkups for 1 student (2%), use of headsets for 48 students (79%), allergic rhinitis 9 students (15%), chronic tonsillitis 17 students (28%) and ISPA 1 student (2%).Conclusion : The percentage of hearing loss is 2%, the type of hearing loss is CHL (Conductive Hearing Loss).  Percentage of risk factors for hearing loss using cotton buds (87%), headset use (79%), allergic rhinitis (15%), chronic tonsillitis (28%), ARI (1%), routine check-ups (1%). Keywords : Hearing loss, hearing function examination, risk factors for hearing loss
DIFFERENCES IN INTERLEUKIN-23 SERUM LEVELS TOWARDS THE SEVERITY OF ACNE VULGARIS IN WOMEN Wafi Banadzir Resya; Novi Kusumaningrum; Santoso Jaeri; Astika Widy Utomo
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 10, No 4 (2021): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v10i4.30029

Abstract

Background: Acne vulgaris is a chronic inflammatory disease in the pilosebaceous gland of the skin which can cause depression and anxiety. IL-23 is a cytokine that is involved in autoimmune diseases, including acne vulgaris. IL-23 affects the differentiation process of Th17 which further produces IL-17, an important component in the pathogenesis of acne vulgaris. IL-17 plays a significant role in the grade of skin damage caused by the inflammation process.Objective: To find out differences in IL-23 serum levels and the grade of AV severity in women.Methods: An observational study with a cross-sectional design approach conducted from June until October 2020 in 15 women with AV aged 15-25 years old, not consuming anti-inflammatory drugs, antibiotics, retinoid group of drugs and free from other inflammatory diseases. Subjects were divided into three groups based on the AV severity grade: specifically mild (n=5), moderate (n=5) and severe (n=5). Subjects had venous blood taken for IL-23 serum content by the ELISA method. Data on IL-23 serum content in the three groups were tested using the One-Way ANOVA method to determine the differenceResults: Average age from the 3 groups was 21 (17-23 ) years old. The results showed that there is no significant difference in IL-23 rate from the 3 groups of AV severities (p=0,490).Conclusion: : There is no significant difference of IP-23 rate between the 3 groups of AV severites in women. 
DIFFERENCES IN TEAR SECRETION BEFORE AND AFTER PHACOEMULSIFICATION SURGERY USING SCHIRMER I TESTS Raditya Pradana Daryosta; Arnila Novitasari Saubig; Maharani Cahyono; Trilaksana Nugroho
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 10, No 4 (2021): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v10i4.30110

Abstract

Background: Cataract is a serious problem in the world because it is the biggest cause of blindness in the world. Cataract healing can only be done with operative measures, one of them is phacoemulsification. The phacoemulsification technique is the latest operative technique for cataract healing but both conventional techniques or phacoemulsification techniques can cause a decrease in tear secretion after cataract surgery. The reduction in tear secretion can be evaluated using the Schirmer I test. In this study an analysis of differences in tear secretion before and after phacoemulsification surgery.Aims: Knowing, comparing, and analyzing the differences in tear secretion before and after phacoemulsification surgery using the Schirmer I test.Methods: 22 cataract eyes consisting of 15 patients who will undergo phacoemulsification surgery were collected by consecutive sampling at the Sultan Agung Eye Center, Sultan Agung Hospital, Semarang from August to September 2019, examined using the Schirmer I test. After the data was collected, data analyzed with Wilcoxon rank test.Results: A total of 15 cataract patients consisting of 10 female patients and 5 male patients with a total of 22 eye samples. The average tear secretion before and after phacoemulsification surgery was 12.77 ± 2.74 mm and 11.00 ± 1.95 mm. Data were tested with the Wilcoxon rank test, p = 0,000 (p <0.05) which showed a difference in average tear secretion before and after phacoemulsification.Conclusion: There are differences in tear secretion before and after phacoemulsification surgery.

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