cover
Contact Name
Muhammad Syahrir
Contact Email
m.syahrir7406@unm.ac.id
Phone
-
Journal Mail Official
nurkhasanah@pharm.uad.ac.id
Editorial Address
Jl. Prof. Dr. Soepomo, S.H., Janturan, Warungboto, Umbulharjo, Yogyakarta, Indonesia Kode pos 55164
Location
Kota yogyakarta,
Daerah istimewa yogyakarta
INDONESIA
Pharmaciana: Jurnal Kefarmasian
ISSN : 20884559     EISSN : 24770256     DOI : 10.12928
Core Subject : Health,
Pharmaciana is a scientific journal published by the University of Ahmad Dahlan worked closely with Ikatan Apoteker Indonesia (IAI). Pharmaciana published three times a year, namely March, July and November. with ISSN 2088-4559 and e-ISSN 2477-0256. The article published in the Journal Pharmaciana selected by editors and reviewed by the reviewer. Articles published in Pharmaciana must not be published in other journals or have been previously published. Pharmaciana is indexed in google scholar, ACI (Asean Citation Index), Dimension (Crossreff), Garuda, Sinta, Sherpa Romeo, Index Copernicus International, DOAJ, and BASE. Pharmaciana is accredited by DIKTI (DGHE) of Indonesia No. 105/E/KPT/2022 April 07, 2022
Articles 28 Documents
Search results for , issue "Vol 6, No 1 (2016): Pharmaciana" : 28 Documents clear
AKTIVITAS ANTIMIKOSIS EKSTRAK ETANOL DAUN SIRSAK (Annona muricata L.) Rohadi, Didi
Pharmaciana Vol 6, No 1 (2016): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (27.514 KB) | DOI: 10.12928/pharmaciana.v6i1.3193

Abstract

Prevalence of Candidiasis is still in high level. Some antimycosis have been less effective so it needs to explore novel sources of antimycosis, one of candidate is the soursop leaves (Annona muricata L.) The aims of this study to observe antimycosis activity of the ethanol extract of soursop leaves at concentration of 15 %, 30 %, and 60 % against Candida albicans ATCC 10231 with agar diffusion method . The results showed that all of the ethanol extract of soursop leaves have exhibited antimycosis activity which concentration-dependent.
UJI ANTIOKSIDAN EKSTRAK ETANOL DAUN DAN KULIT BATANG MANGGIS Garcinia mangostana L. Diniatik, Diniatik; Suparman, Suparman; Anggraeni, Dewi; Amar, Ibnu
Pharmaciana Vol 6, No 1 (2016): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (391.576 KB) | DOI: 10.12928/pharmaciana.v6i1.3314

Abstract

Antioxidant was a compound which possessed an activity as scavenger of free radicals. This study was aimed to examine the antioxidant activity of ethanolic extract from leaves and skin barks of Garcinia mangostana. Antioxidant activity were evaluated by using DPPH method for ethanolic extract in serial concentration of 800, 400, 200 and 100ug/mL. The result found that ethanolic extract of leaves and skin barks of Garcinia mangostana showed antioxidant activity with IC50 value of 674.947 ug/mL and 565.759 ug/ml, they were eleven and ten times weaker than d-α-tocopherol (IC50 57,114 ug/mL) which were used as a control. In conclusion, EE from leaves and skin barks of Garcinia mangostana exhibited an activity as scavenger of free radicals from DPPH.
POLA PENGOBATAN PASIEN SCHIZOPRENIA PROGRAM RUJUK BALIK DI PUSKESMAS MUNGKID PERIODE JANUARI-JUNI 2014 Hariyani, Hariyani; Astuti, Fitriana Yulia; Kusuma, Tiara Mega
Pharmaciana Vol 6, No 1 (2016): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (45.856 KB) | DOI: 10.12928/pharmaciana.v6i1.2825

Abstract

Schizoprenia is one of psychiatric disorders that caused by brain damage. One of schizoprenia handling is giving antipsychotics to prevent the symptoms, that antipsychotics was effective therapy to treat it. This study aims to determine the treatment pattern of schizoprenia patient behind reconciliation program at Puskesmas Mungkid. The method used is analytical survey with retrospective data collection. This research were conducted on 42 medical records of patients in period January-June 2014 which receive antipsychotics medication and were analyzed with descriptive analysis. Obtained data of this research, showed that the most common single therapy of for antipsychotics is haloperidol (54,93%) and the most common therapy was haloperidol and chlopromazine (61,91%). The most common treatment category of schizoprenia is the typical antipsychotic treatmemt (92,96%), while for appropriate dose and the use of antipsychotic drugs were used 97,18% and 2,82% were not appropriate to the standar.
UJI AKTIVITAS PENYUBUR RAMBUT KOMBINASI EKSTRAK AIR TEH HIJAU DAN HERBA PEGAGAN Sulastri, Lela; Indrawati, Teti; Taurhesia, Shelly
Pharmaciana Vol 6, No 1 (2016): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (467.462 KB) | DOI: 10.12928/pharmaciana.v6i1.3194

Abstract

Hair fertilizer was used to stimulate hair growth that is used topically on the scalp. Natural materials are expected to be used as fertilizer hair is green tea leaves and herb gotukola. Because the green tea leaves contain a chemical polyphenol compounds that are flavonoids and their derivatives and herb gotukola contain lead compound triterfenoid saponin that are asiatikoside, flavonoids, phytosterols, madecassid acid, madecassoside, asiatic acid and amino acids are thought to have properties as fertilizer hair. This study was conduced to determine whether the combination of the water extract of green tea leaves and herb gotukola has activity as a hair fertilizer and combination which has the most optimum activity. Test hair fertilizer activities include the rate of hair growth, hair growth acceleration and the weight of the hair. In this study used three combinations are combination 1 ( the water extract of green tea leaves and 5% water gotukola herb extract 2.5%), combination 2 (the water extract of green tea leaf extract 7.5% and 2.5% water gotukola herb) and combination 3 (the water extract of green tea leaves and 5% water gotukola herb extract 7.5%). The results showed the combination of the water extract of green tea leaves and water extract herb gotukola has activity as fertilizer hair and extract the most optimum combination is a combination of 1 with a concentration of water extract of green tea leaves (5%) and water extract of the herb gotukola (2.5%) the rate of hair growth 2.689 cm in 28 days, accelerated hair growth 0.128 cm / day and the hair weighs 0.1938 grams in 28 days.
ANALISIS ADVERSE DRUG REACTIONS OBAT ANTI RETROVIRAL PADA PENGOBATAN PASIEN HIV/AIDS DI RSUD GUNUNG JATI CIREBON TAHUN 2013 Hidayati, Nur Rahmi; Abdillah, Syamsudin; A. Keban, Sesilia
Pharmaciana Vol 6, No 1 (2016): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (262.144 KB) | DOI: 10.12928/pharmaciana.v6i1.3327

Abstract

Acquired Immunodeficiency Syndrome (AIDS) is a disease caused by infection with Human Immunodeficiency Virus (HIV). The pharmacology treatment for the infection was antiretroviral therapy. The problem from the use of antiretroviral drugs (ARV) is the emergence of unwanted drug reactions (adverse drug reaction). The purpose of this study was to identify and analyze the incidence of adverse drug reactions from the use of antiretroviral drugs in the treatment of patients with HIV / AIDS that occurred in RSUD Gunung Jati Cirebon. This study involves 122 patients. Data were obtained from medical records and patient interview form. The data were evaluated with a descriptive analysis of demographic profile of patients and the percentage of adverse drug reaction (ADR) The results showed an adverse drug reaction (ADR) on the use of antiretroviral drugs in the treatment of patients with HIV / AIDS in RSUD Gunung Jati Cirebon. ARV regimens are the most widely used is the combination of Zidovudine + Lamivudine + Nevirapine / Efavirenz (AZT + 3TC + EFV) as much as 31.2% (38 people). Duration of therapy ARV in Seroja Clinic RSUD Gunung Jati Cirebon most is> 2 years - 4 years 28.7% (35 people). Types of adverse drug reaction (ADR), which occurs in the use of antiretroviral drugs in the treatment of patients with HIV / AIDS in RSUD Gunung Jati Cirebon include: headache (22.1%), fatigue (6.8%), anemia (9.3%), itching (14.4%), nausea / vomiting (20.1%), diarrhea (7.2%), lipodystrophy (2.0%), rash (11.3%), skin discoloration (1.6%), neuropathy (1.6%) and sleep disorders (3.6%).
HUBUNGAN TINGKAT PENGETAHUAN DENGAN KEPATUHAN BEROBAT DI KLINIK PROGRAM TERAPI RUMATAN METADON DI PUSKESMAS PARAKAN KABUPATEN TEMANGGUNG Martiani, Sari Dwi; Yati, Heni Lutfi; K, Tiara Mega
Pharmaciana Vol 6, No 1 (2016): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (396.826 KB) | DOI: 10.12928/pharmaciana.v6i1.2828

Abstract

Psycho active substance abuse is a common problem throughout the world, and it is associated with the increase of mortality and morbidity. One of substitution therapy program is methadone maintenance therapy program. The main problem is most of patients stop following the maintenance program before they feel the therapeutic effects of it. Compliance in taking daily medication is the focus in achieving the health status of patients. The research objective is to determine the relationship between the knowledge level with methadone maintenance therapy program in the public health center of Parakan, District of Temanggung. The research method was cross sectional approach. The population in this study were all patients of methadone maintenance therapy program in the public health centers of Parakan, District of Temanggung. Samples on this research were 31 patients and they are all active on methadone maintenance therapy program in the public health center of Parakan, District of Temanggung. Data analysis was performed using Chi Square (x2) formula correlation test. The results show there is a relationship between knowledge level with methadone maintenance therapy program in the public health center of Parakan, District of Temanggung with p value 0.001, with 13 respondents (42%) are in a good level of knowledge category and methadone treatment in obidiance catagory is 11 respondents (35.5%). It is concluded that there is a relationship between methadone maintenance therapy program in the public health center of Parakan, District of Temanggung.
AKTIVITAS ANTIOKSIDAN EKSTRAK Andrographis paniculata (Burm.f.) Ness DENGAN DUA PERBEDAAN PENGUAPAN Rais, Ichwan Ridwan
Pharmaciana Vol 6, No 1 (2016): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (601.322 KB) | DOI: 10.12928/pharmaciana.v6i1.3226

Abstract

Andrographis paniculata (Burm.f.) Ness is one of the native tradisional medicine in Indonesia which contain active flavonoid. It has potential activity as antioxidant, antibacterial, and inflammation. Antioxidant sensitive to light and heat. Flavonoid antioxidant activity could be decline by heat and oxidation. We can find these caution while evaporate the liquid solvent with heating in conventional evaporation to get dry extract. One of the conventional evaporation instrument is Rotary Evaporator. Other evaporation system, lyophillization is alternative to evaporate solvent without heat. This system uses instrument called Freeze Dryer. Present study about antioxidant activity influenced by two different evaporation using IC50 determination in DPPH oxidation proved that evaporation difference could change antioxidant ability. The result shows freeze dryer evaporation result with 17.06% of extract yield and 585.730 µg/mL IC50 value better than rotary evaporator with 24.96% of extract yield and 792.196 µg/mL IC50 value in solvent evaporate ability and antioxidant activity.
UJI AKTIVITAS KOMBINASI EKSTRAK AIR LIDAH BUAYA ( Aloe vera L.) DAN AKAR MANIS (Glycyrrhiza glabra L.) SEBAGAI PENYUBUR RAMBUT Indriaty, Sulistiorini; Indrawati, Teti; Taurhesia, Shelly
Pharmaciana Vol 6, No 1 (2016): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (405.054 KB) | DOI: 10.12928/pharmaciana.v6i1.3235

Abstract

Aloe vera (Aloe vera L.) contains amino acids, vitamins, folic acid, and liquorice (Glycyrrhiza glabra L) containing glisirizin, and flavonoids, which have properties as fertilizer hair. This study aims to obtain a combination of extracts with activity most optimal fertilizer hair, made 3 combination with a combination of 1 (the water extract of liquorice concentration of 2.5% and 7.5% aloe vera), a combination of 2 (the water extract of liquorice concentrations of 2, 5% and 2.5% aloe vera), and combinations of 3 (the water extract of liquorice concentration of 5% and 7.5% aloe vera). Testing the activity of hair growth is done by measuring the rate of hair growth, hair growth acceleration and weight of rabbit hair for 28 days. Rabbit hair growth results showed the combination 1 has an average length of the largest hair with hair growth rate value of 2.97 cm, accelerated hair growth amounted to 0.15 cm / day on day 7 and weighing 0.13 gram hair.
PENGARUH PEMBERIAN EKSTRAK ETANOL DAUN KELOR (Moringa oleifera L.) TERHADAP AKTIVITAS ANALGESIK DAN ANTIINFLAMASI MELALUI EKSPRESI ENZIM SIKLOOKSIGENASE Sulistyawati, Rini; Pratiwi, Pramita Yulli
Pharmaciana Vol 6, No 1 (2016): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (17.566 KB) | DOI: 10.12928/pharmaciana.v6i1.3043

Abstract

Kelor (Moringa oleifera L.) contains flavonoid as a major of bioactive constituent. Quercetin as a flvonoid group inhibits COX-2 in inflammatory process. This study aimed to determine the effect of etanol extract of the kelor leaves on the analgesics and antiiinflamatory in mice. Etanol extract of the kelor leaves were evaluated for analgesics activity through writhing assay test at doses of 12.5; 25 and 50 mg/kgBW using  Swiss albino mice. On the other hand antiinflammatory assay was performed by carrageenan induced paw edema of the etanol extract of the kelor leaves at 35; 70 and 140 mg/kgBW. Aspirin and sodiumdiclofenac were employeed as a standard for analgesic and antiinflammatory studies respectively. The result of the analysis show that etanol extract of the kelor leaves at doses 25 and 50 mg/kgBW decrease the number of writhing so that it have an analgesic power of 76.41±2.73% and 80.41±5.20%. Etanol extract of the kelor leaves at dosage 140 mg/kgBW show 24.30±2.960% antiinflammatory power and 46.37±6.434% on decreased COX-2 expression.
STUDI KINETIKA ADSORPSI Al-MCM 41 TERHADAP METILEN BIRU Ahda, Mustofa; Sutarno, Sutarno; Kunarti, Eko Sri
Pharmaciana Vol 6, No 1 (2016): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (338.665 KB) | DOI: 10.12928/pharmaciana.v6i1.3290

Abstract

The synthesis and kinetics studies of Al-MCM 41 of the methylene blue adsorption have been done. The observations of the adsorption kinetics are very important parameter in the adsorption process. This is the higher of adsorption kinetics tend to faster adsorption process. The results of characterization of Al-MCM 41 have a wall thickness is 15.173 Å, Pore Volume Pore is 0.584 cm3/g, Pore Diameter is 30.446 Å, Surface Area is 995.513 m2/g. The results of the adsorption kinetics of Al-MCM 41 to  methylene blue adsorption follows pseudo second order with coefficient of determination (r2) value of 0.999 and the value of adsorption rate constant of Al-MCM 41 is 10-2 g.mg-1.min-1.

Page 1 of 3 | Total Record : 28


Filter by Year

2016 2016


Filter By Issues
All Issue Vol 14, No 1 (2024): Pharmaciana Vol 13, No 3 (2023): Pharmaciana Vol 13, No 2 (2023): Pharmaciana Vol 13, No 1 (2023): Pharmaciana Vol 12, No 3 (2022): Pharmaciana Vol 12, No 2 (2022): Pharmaciana Vol 12, No 1 (2022): Pharmaciana Vol 11, No 3 (2021): Pharmaciana Vol 11, No 2 (2021): Pharmaciana Vol 11, No 1 (2021): Pharmaciana Vol 10, No 3 (2020): Pharmaciana Vol 10, No 2 (2020): Pharmaciana Vol 10, No 1 (2020): Pharmaciana Vol 9, No 2 (2019): Pharmaciana Vol 9, No 1 (2019): Pharmaciana Vol 8, No 2 (2018): Pharmaciana Vol 8, No 2 (2018): Pharmaciana Vol 8, No 1 (2018): Pharmaciana Vol 8, No 1 (2018): Pharmaciana Vol 7, No 2 (2017): Pharmaciana Vol 7, No 2 (2017): Pharmaciana Vol 7, No 1 (2017): Pharmaciana Vol 7, No 1 (2017): Pharmaciana Vol 6, No 2 (2016): Pharmaciana Vol 6, No 2 (2016): Pharmaciana Vol 6, No 1 (2016): Pharmaciana Vol 6, No 1 (2016): Pharmaciana Vol 5, No 1 (2015): Pharmaciana Vol 5 No 1, 2015 Vol 5, No 2 (2015): Pharmaciana Vol 5, No 2 (2015): Pharmaciana Vol 5, No 1 (2015): Pharmaciana Vol 5, No 1 (2015): Pharmaciana Vol 4, No 2 (2014): Pharmaciana Vol 4, No 2 (2014): Pharmaciana Vol 4, No 1 (2014): Pharmaciana Vol 4, No 1 (2014): Pharmaciana Vol 3, No 2 (2013): Pharmaciana Vol 3, No 2 (2013): Pharmaciana Vol 3, No 1 (2013): Pharmaciana Vol 3, No 1: Mei 2013 Vol 3, No 1 (2013): Pharmaciana Vol 2, No 2 (2012): Pharmaciana Vol 2, No 2 (2012): Pharmaciana Vol 2, No 2: November 2012 Vol 2, No 1: Mei 2012 Vol 2, No 1 (2012): Pharmaciana Vol 2, No 1 (2012): Pharmaciana Vol 1, No 2 (2011): Pharmaciana Vol 1, No 2: November 2011 Vol 1, No 2 (2011): Pharmaciana Vol 1, No 1 (2011): Pharmaciana Vol 1, No 1 (2011): Pharmaciana Vol 1, No 1: Mei 2011 More Issue