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All Journal Jurnal Ilmu Farmasi dan Farmasi Klinik (Journal of Pharmaceutical Science and Clinical Pharmacy) Jurnal Farmasi dan Sains Indonesia (JFSI) Jurnal DiMas (Jurnal Pengabdian Kepada Masyarakat) Media Farmasi Indonesia
Ririn Suharsanti
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health Other

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Pembuatan Olahan Toga Sirup Herbal Masyarakat Di Kelurahan Colo Kecamatan Dawe Kudus Lilies Wahyu Ariani; Ririn Suharsanti; Yustisia Dian Advistasari; Rika Sebtiana Kristantri; Wahyu Wulandari
Jurnal Dimas Vol 4 No 1 (2022): Jurnal Pengabdian Kepada Masyrakat
Publisher : Jurnal DiMas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53359/dimas.v4i1.34

Abstract

Masyarakat di kawasan Pegunungan Muria, Kecamatan Dawe, Kabupaten Kudus, selain sebagai petani kopi juga banyak menanam Tanaman Obat Keluarga (TOGA) di lingkungan sekitarnya. Banyaknya toga yang ditanam oleh masyarakat dapat dikembangkan menjadi suatu produk yang dapat dipasarkan melalui pasar wisata yang ada di wilayah Colo sebagai tempat wisata religi. Salah satu jenis pelatihan dari Pengabdian masyarakat adalah pelatihan pembuatan minuman kesehatan berbasis herbal sirup empon-empon yang bisa dijual di tempat wisata religi Colo. Kegiatan PKM ini dilaksanakan pada bulan Oktober 2021 dengan metode yang digunakan dalam kegiatan ini meliputi ceramah, tanya jawab, dan demonstrasi. Kegiatan ini melibatkan dosen dengan berbagi tugas sebagai fasilitator, Instruktur sebagai pendemonstrasi, Ibu lurah sebagai perwakilan masyarakat untuk sambutan, serta kader ibu-ibu PKK sebagai peserta. Kegiatan yang diawali dengan pemaparan materi pelatihan oleh Tim PKM, dilanjutkan dengan pendampingan praktek pembuatan minuman kesehatan berbasis herbal. Target kegiatan PKM ini adalah meningkatnya keterampilan kader ibu-ibu PKK peserta pelatihan dalam pembuatan minuman kesehatan berbasis herbal. Kata Kunci: Kelurahan Colo; TOGA; Sirup Herbal Empon-empon
PENGARUH GAYA HIDUP TERHADAP KENAIKAN TEKANAN DARAH DI KOTA SEMARANG Erna Prasetyaningrum; Ririn Suharsanti
Media Farmasi Indonesia Vol. 12 No. 1 (2017): Media Farmasi Indonesia
Publisher : SEKOLAH TINGGI ILMU FARMASI YAYASAN PHARMASI SEMARANG

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Abstract

ABSTRACT One of the degenerative diseases causing death was cardiovascular diseases. Hypertension is a major risk factor for cardiovascular found in 14% of the Indonesian population. Many risk factors that cause hypertension are lifestyle habits such as smoking, drinking alcohol, fatty foods. The aim of research is to know the correlation between the lifestyle of the community blood pressure rise in Semarang. Research is a non-experimental research. The variables studied are gender, age, smoking behavior, relish eating fried foods, offal, fat, drinking sodas and coffee. The research subject is Jatisari village community Mijen Subdistrict, District Limbangan boja and Muktiharjo Tlogosari Semarang. The number of subjects are 54 people, at least 20 years old. Collecting data is carried out using interview techniques and measurement of blood is performed pressure using a sphygmomanometer. Data were analyzed by descriptive analytic. The results showed that increased blood pressure in people Semarang based on gender male by 29.6%, amounting to 70.4% of women, by the age of 20-30 years was 1.8%, 30-40 th of 3.7 %, 7.5% 40-50 years old, 50-60 years old 31.5%, 60-70 years old amounted to 35.2%,> 70 th by 20.4%, amounting to 20.7% of smoking, eating fries 44.6%, eating offal of 5.4%, 11.9% fat meal, drink soft drinks by 3.3%, coffee by 20.7%, 6.5% high-salt foods. The education related to the symptoms, risk factors, treatment of hypertension and prevention of complications through printed and electronic media can prevent hypertension or other complications.
KARAKTERISTIK FISIK DAN INDEKS IRITASI PADA SEDIAAN SHOOTING GEL KOMBINASI LIDAH BUAYADAN BUAH ANGGUR Ririn Suharsanti; Lilies Wahyu Ariyani
Media Farmasi Indonesia Vol. 13 No. 1 (2018): Media Farmasi Indonesia
Publisher : SEKOLAH TINGGI ILMU FARMASI YAYASAN PHARMASI SEMARANG

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Abstract

ABSTRACT Shooting gel is one of cosmetic preparations that work to overcome dry skin. High active ingredients in shooting gel are considered able to rehydrate the skin, especially dry skin. In this research will be formulated shooting gel preparation with active ingredients ofAloe vera and grapes. The famous Aloe vera helps to moisturize the skin while the grapes also contain active compounds that are efficacious as antioxidants that are good for the skin. Therefore, the combination of these two active ingredients should be developed on the shooting gel preparation. This study aims to see the spread, stickiness, pH, viscosity, irritation of shooting gel with variations of concentration of active ingredients of Aloe vera and grapes. This research was started with formulation of shooting gel preparation with combination concentration of active ingredient 80% (FI); 85% (FII); 90% (FIII). Shooting gel is evaluated physical characteristics with parameters spreadibility, adhesivity,viscosity and pH. It was also evaluated the irritation index of the skin using male rats. The data obtained were analyzed with different 95% confidence level test to know the existence of significant difference between treatment groups. The experimental results of shooting gel physical characteristics showed that the concentration variation did not affect the adhesivity (p> 0.05) but affects pH, viscosity and spreadibility (p <0.05). Shooting gel with all three concentrations did not irritate the skin of male rats.
UJI AKTIVITAS ANTIJAMUR EKSTRAK ETANOL DAUN SOM JAWA TERHADAP PERTUMBUHAN Candida albicans UNTUK MENJAMIN MUTU PENGGUNAAN SEBAGAI OBAT HERBAL ANTIKEPUTIHAN Ririn Suharsanti; F.X. Sulistyanto Wibowo
Media Farmasi Indonesia Vol. 11 No. 2 (2016): Media Farmasi Indonesia
Publisher : SEKOLAH TINGGI ILMU FARMASI YAYASAN PHARMASI SEMARANG

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Abstract

ABSTRACT Empirically, leaves and roots of som Java (Talinum triangulare (Jacq.) Willd) has been used as a whiteness medicinal drug efficacious. This study aims to better ensure the quality of ethanolic leaf extract som Java as whiteness herbal medicine based test antifungal activity against Candida albicans growth. The method used was agar diffusion method with PDA (Potatoes Dextrose Agar) were inoculated Candida albicans, then filled with test compounds antimicrobials that are reconstituted with the solvent DMSO extract concentration, incubated for 3x24 hours at a temperature of 25°C, observations were made by measuring the inhibition zone around sinks. Antifungal activity test showed inhibition zone began to extract the solvent DMSO concentration of 40% amounting to 1.380 ± 0.028, increasing the concentration of the inhibitory zones is increasing as well. This is due to the increasing concentration, it also increase the active substance content which are within the extract that can serve as an antifungal
POTENSI TABIR SURYA SERTA KANDUNGAN FENOLIK DAN FLAVONOID TOTAL EKSTRAK ETANOL DAUN JATI CINA (Cassia Angustifolia) PADA BERBAGAI KONSENTRASI PELARUT Ririn Suharsanti; Lilies Wahyu Ariani
Media Farmasi Indonesia Vol. 14 No. 1 (2019): Media Farmasi Indonesia
Publisher : SEKOLAH TINGGI ILMU FARMASI YAYASAN PHARMASI SEMARANG

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Abstract

Daun jati cina yang biasa dikenal sebagai pelangsing memiliki kandungan senyawa fenolik yang cukup tinggi. Adanya kandungan fenolik ini membuat daun jati cina menarik untuk digali lebih lanjut potensinya sebagai tabir surya. Penelitian ini bertujuan untuk membandingkan kandungan fenolik total dan flavonoid total serta potensi tabir surya dengan nilai sun protection factor (SPF), persen transmisi eritema (% Te) dan persen transmisi pigmentasi (% Tp) daun jati cina yang dimaserasi menggunakan pelarut etanol 50%, 70% dan 96%. Metode penetapan kadar fenolik total menggunakan Folin-Ciocalteu dengan standar asam galat sedangkan flavonoid total menggunakan AlCl3 dengan standar rutin. Penentuan nilai SPF, % Te dan % Tp menggunakan metode spektrofotometri Uv-Vis. Hasil pengukuran total fenolik ekuivalen asam galat dan total flavonoid ekuivalen rutin pada pelarut etanol 50%, 70% dan 96% berturut turut adalah 7,10 mg EAG (ekivalen asam galat)/g dan 65,10 mg ER (ekivalen rutin)/g; 7,96 mg EAG/g dan 23,16 mg ER/g serta 14,83 mg EAG/g dan 155,17 mg ER/g. Ekstraksi dengan pelarut etanol 96% mampu menarik senyawa fenolik dan flavonoid tertinggi dibandingkan yang lain. Nilai SPF pada pelarut etanol 50%, 70% dan 96% berturut turut adalah 17,63; 15,88 dan 23,89. Nilai % Te dan % Tp pada pelarut etanol 50%, 70% dan 96% berturut turut adalah 6,29% dan 3,64%; 9,51% dan 7,00% serta 1,91% dan 0,97%. Nilai SPF daun jati cina pada semua konsentrasi pelarut etanol memiliki kategori ultra karena berada pada nilai di atas 15 dengan nilai SPF terbaik pada ekstraksi dengan pelarut etanol 96%. Nilai hasil %Te dan %Tp ekstraksi daun jati cina dengan pelarut etanol 96% dikatakan paling baik menahan kulit untuk mencegah kemerahan (eritema) dan menahan penggelapan kulit (pigmentasi) dengan kategori ekstra proteksi.
KADAL IRAN (ETHANOL CONTENT NIRA SIWALAN (Borassus flabellifer)) WITH GC-MS (GAS CHROMATOGRAPHY MASS SPECTROMETRY) ANALYSIS Maria Ulfa; Retno Yuni Astuti; Rizky Bachrul Alam; Ririn Suharsanti
Media Farmasi Indonesia Vol. 14 No. 2 (2019): Media Farmasi Indonesia
Publisher : SEKOLAH TINGGI ILMU FARMASI YAYASAN PHARMASI SEMARANG

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Abstract

There are many siwalan saplings among the people who utilize various kinds of fruit,leaves, nira siwalan. However, many people like the fruit and the water. In this case, legenlontar or other names nira siwalan can produce ethanol from siwalan flowers. So that, frommany people using nira only as a drink and so far some people produce nira on a small scale.Nira is a liquid that contains certain sugar levels, namely sucrose, glucose, fructose andcarbohydrates, which have an average acidity level of 6-7 and smell nice. This study aims todetermine the amount of ethanol content contained in nira siwalan and determine the effect ofstorage time on ethanol levels in nira siwalan. Samples of nira siwalan both original andbulk were fermented for 3 days, 6 days, and 9 days and then distilled at a temperature of78.37 ° C. Determination of ethanol content in the distillate results was carried out usingGCMS (Gas Chromatography Mass Spectrometry). The results of this study are the originalethanol content of nira siwalan at storage of 3.6.9 consecutive days, namely 0.27%, 0.91%,and 1.02%. While the results of the bulk ethanol juice of the siwalan level at storage of 3,6.9days were obtained ethanol levels respectively ie 32.05%, 39.99% and 44.42%. From thisstudy it can be concluded that the ethanol content in bulk nira siwalan is more than theoriginal nira siwalan.
UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL, AIR BUNCIS (Phaseolus vulgaris L.) DAN FRAKSI-FRAKSINYA TERHADAP PERTUMBUHAN BAKTERI Staphylococcus aureus Yosua Bayu Kristianto; Indah Sulistyarini; Ririn Suharsanti
Media Farmasi Indonesia Vol. 14 No. 2 (2019): Media Farmasi Indonesia
Publisher : SEKOLAH TINGGI ILMU FARMASI YAYASAN PHARMASI SEMARANG

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Abstract

Infection is a disease caused by the entry of a pathogenic microorganism in the body'stissues. One of the bacteria that can cause infection is Staphylococcus aureus. Beans are oneof the plants that contain alkaloids, flavonoids and saponins. Which is believed to inhibit thegrowth of Staphylococcus aureus bacteria. This study aims to determine the antibacterialactivity of extracts and its fraction on the growth of Staphylococcus aureus bacteria atconcentrations of 5%, 10%, and 15%. Bean powder was remacerated with 70% ethanol for 3days, and the extract obtained was subjected to fractionation with n-hexane, ethyl acetate,and water using a separating funnel. The antibacterial activity on the extract and eachfraction was made with a concentration of 5, 10, and 15% using the agar well method.Dimethyl Sulphoxide (DMSO) as a negative control and ciprofloxacin 0.005% as a positivecontrol. Antibacterial activity was measured using the inhibition zone diameter of bacterialgrowth. The results showed that the average inhibition zone diameter of ethanol extract, nhexanefraction and ethyl acetate fraction of beans at concentration of 5%, 10% and 15%respectively were of 0.842; 0.935 and 1.042 cm. The n-hexane fraction is 0.595; 0.787; and0.947 cm. Ethyl acetate fraction of 0.926; 1,008 and 1,049 cm. Whereas the water fractiondoes not provide antibacterial activity. The contact bioautography test results showed thatalkaloid compounds, flavonoids and saponins were able to inhibit the growth ofStaphylococcus aureus bacteria. The conclusions of this study are ethanol extract, n-hexanefraction, and ethyl acetate fraction of chickpeas having antibacterial activity againstStaphylococcus aureus bacteria, but the water fraction has no antibacterial activity against S.aureus; there was a significant difference (p <0.05) between the extract, n-hexane fraction,ethyl acetate fraction and water fraction.
PEMANFAATAN EKSTRAK ETANOL DAUN SOM JAWA SEBAGAI OBAT HERBAL ANTIKEPUTIHAN DALAM SEDIAAN SABUN CAIR Erna Prasetyaningrum; Ririn Suharsanti; Wahyuning Setyani
Jurnal Ilmu Farmasi dan Farmasi Klinik Prosiding Seminar Nasional "Perkembangan Terbaru Pemanfaatan Herbal Sebagai Agen Preventif Pada Tera
Publisher : Universitas Wahid Hasyim Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (199.308 KB) | DOI: 10.31942/jiffk.v0i0.1206

Abstract

ABSTRAK Telah dilakukan penelitian mengenai formulasi sabun cair dengan ekstrak daun som jawa berbagai konsentrasi. Penelitian ini bertujuan untuk mengetahui kualitas ekstrak etanol daun som jawa sebagai obat herbal antikeputihan dalam sediaan sabun cair, mengetahui aktivitas antijamur sediaan terhadap Candida albicans dan mengetahui konsentrasi ekstrak daun som jawa yang efektif sebagai bahan jamur dalam sediaan sabun cair. Pengujian kualitas sabun cair telah disesuaikan dengan aturan Standar Nasional Indonesia (SNI) yang meliputi pengamatan skrining fitokimia, organoleptis, pH, viskositas, bj selama waktu penyimpanan. Dari hasil penelitian kestabilan fisika, kimia dan mikrobiologi diketahui bahwa sabun cair ekstrak daun som jawa relatif stabil selama penyimpanan. Hasil penelitian menyimpulkan bahwa uji organoleptis dari sediaan kurang nyaman jika dipakai karena bau dan warna yang tidak menarik. Sedangkan pada uji pH konsentrasi 30%,40% dan 50% memenuhi persyaratan lebih dari 8, viskositas dan bobot jenis sediaan memenuhi syarat lebih dari 1,01-1,10. Uji aktivitas antijamur menunjukkan hasil yang positif pada konsentrasi 40% dan 50 % yang diujikan. Kata kunci: antijamur, antikeputihan, Candida albicans, daun som jawa, sabun cair
STANDARISASI EKSTRAK DAUN SOM JAWA (Talinum paniculatum (Jacq) Gaertn) UNTUK MENJAMIN MUTU PENGGUNAAN SEBAGAI OBAT HERBAL Ririn Suharsanti; FX Sulistyanto Wibowo
Jurnal Ilmu Farmasi dan Farmasi Klinik Prosiding Seminar Nasional "Perkembangan Terbaru Pemanfaatan Herbal Sebagai Agen Preventif Pada Tera
Publisher : Universitas Wahid Hasyim Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (215.621 KB) | DOI: 10.31942/jiffk.v0i0.1221

Abstract

ABSTRAK Daun som jawa diketahui sebagai tanaman obat di Indonesia yang memiliki aktivitas biologi sebagai antibakteri, antiinflamasi, dan memperlancar ASI. Agar dapat digunakan sebagai bahan aktif sediaan obat, perlu dilakukan standarisasi ekstrak untuk menjamin mutu dan keamanannya. Standarisasi ekstrak etanol daun som jawa telah dilakukan sesuai dengan metode standarisasi dari literatur meliputi penentuan parameter spesifik dan non spesifik. Hasil penelitian menunjukkan bahwa ekstrak etanol  karakteristik berupa ekstrak kental berwarna hijau kecoklatan, rasa pahit dan berbau khas, mengandung kadar senyawa yang larut dalam air sebesar 36,71 ± 1,36%, kadar senyawa yang larut dalam etanol sebesar 18,62 ± 1,76%, kadar air sebesar 11,77 ± 1,64%, kadar abu sebesar 27,57 ± 0,98%, kadar abu tidak larut asam sebesar 27,57 ± 0,98%, berat jenis ekstrak sebesar 0,90412 ± 0,0008 sampai 1,22260 ± 0,0001, total cemaran bakteri < 1x106 koloni/g dan kapang < 2x104 koloni/g dan kadar logam berat Pb ≤ 10,0 ppm. Ekstrak etanol daun som jawa telah memenuhi syarat sebagai ekstrak terstandar sehingga dapat menjadi acuan dalam identifikasi dan kontrol kualitas. Kata kunci : Daun som jawa, parameter spesifik, parameter non spesifik, standarisasi
Co-Authors A. Ariani Hesti Wulan Achmad wildan Christina Astutiningsih Dwi Hadi Setya Palupi Erlita verdia M Erlita Verdia M. erna prasetyaningrum F.X. Sulistyanto Wibowo FX Sulistyanto Wibowo Indah Sulistyarini Kristantri, Rika Sebtiana Lilies Wahyu Ariani Lilies Wahyu Ariani Lilies Wahyu Ariyani M. Ryan Radix Maria Ulfa Retno Yuni Astuti Rika Sebtiana Rika Sebtiana K Rizky Bachrul Alam Wahyu Wulandari Wahyuning Setyani Wulan Kartika Sari Yosua Bayu Kristianto Yustisia Dian Advistasari